Title: South Carolina Midlands Villas from CA $107 | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.ca/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-01-30&endDate=2026-02-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 8 - May 10](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in South Carolina Midlands ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2544034c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2a6d6c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/fcf4fdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/5cc0357e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Latta by IHG [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) 9.6/10 Exceptional (538 reviews) "The staff was great and the room was very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark Whitehurst CA $174 CA $189 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0c64863b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0b9239a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) 9.0/10 Wonderful (2,231 reviews) "Room was clean, staff friendly, and the includes breakfast was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha CA $118 CA $132 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/22000/21992/2f1f8cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LCD TV](https://images.trvl-media.com/lodging/1000000/30000/22000/21992/bea66887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard king non smoking](https://images.trvl-media.com/lodging/1000000/30000/22000/21992/b241d6b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/30000/22000/21992/5f4afc1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Rock Hill [](https://www.expedia.ca/Rock-Hill-Hotels-Hampton-Inn-Rock-Hill.h21992.Hotel-Information) 9.2/10 Wonderful (1,002 reviews) "We have stayed here several times and it never disappoints! Room is clean, staff very friendly, and they provide a great breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erma CA $113 CA $125 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Rock-Hill-Hotels-Hampton-Inn-Rock-Hill.h21992.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fad493a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/6df606aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) 9.2/10 Wonderful (1,184 reviews) "Nice staff, clean, , convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kathleen CA $129 CA $144 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/d654e116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) 9.8/10 Exceptional (1,003 reviews) "Clean spacious room, nice amenities and good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $168 CA $187 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/40f69ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/99021580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) 9.2/10 Wonderful (680 reviews) "Stay was great felt so welcomed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse CA $149 CA $165 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/a93e569b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/0e00b7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) 9.0/10 Wonderful (1,002 reviews) "Only stayed for a night, but everything was excellent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nelson CA $139 CA $156 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/e8ed92ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/55a9de69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/0ec38ec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/92000000/91270000/91267900/91267861/df416cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Springhill Suites by Marriott Columbia near Fort Jackson [](https://www.expedia.ca/Columbia-Hotels-Springhill-Suites-By-Marriott-Columbia-Southeast.h91267861.Hotel-Information) 9.4/10 Exceptional (587 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Howard CA $136 CA $152 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/Columbia-Hotels-Springhill-Suites-By-Marriott-Columbia-Southeast.h91267861.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/b50995e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/3fbd24c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/2db4f7f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) 7.8/10 Good (1,000 reviews) "Very Clean and newly renovated. Decent breakfast and helpful staff." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Elizabeth CA $96 CA $107 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1170000/1160800/1160796/bcb0f0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1170000/1160800/1160796/87830651.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/2000000/1170000/1160800/1160796/12c9570f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1170000/1160800/1160796/7cb8c23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Columbia Airport, SC [](https://www.expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1160796.Hotel-Information) 8.4/10 Very good (1,000 reviews) "Clean room, friendly staff, definitely recommend!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron CA $129 CA $143 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1160796.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/d098e4c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/3b39bfd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/ecf8f7be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/549be75d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Newberry by IHG [](https://www.expedia.ca/Newberry-Hotels-Holiday-Inn-Express-Suites-Newberry.h2803681.Hotel-Information) 9.0/10 Wonderful (640 reviews) "Yes the young lady that was taking care of the breakfast was super. She did a great job on the food and keeping the place cleaned. Rooms were very clean. Will definitely be staying again in the future. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patsy CA $163 CA $176 total includes taxes & fees Jan 23 - Jan 24 [](https://www.expedia.ca/Newberry-Hotels-Holiday-Inn-Express-Suites-Newberry.h2803681.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) 8.0/10 Very good (1,424 reviews) "Always a great stay. Clean room, friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $104 CA $116 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/f2adc30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/eb4d1288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) 9.2/10 Wonderful (1,000 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $158 CA $176 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/80c72ac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/f8e60dad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/70afa25a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/1000000/30000/22100/22006/5ac087d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Pointe Rock Hill Near University [](https://www.expedia.ca/Rock-Hill-Hotels-Clarion-Pointe-Rock-Hill-Near-Training-Camp.h22006.Hotel-Information) 8.8/10 Excellent (1,048 reviews) "Stay was good area felt safe, would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean CA $96 CA $107 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Rock-Hill-Hotels-Clarion-Pointe-Rock-Hill-Near-Training-Camp.h22006.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/26a37b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/aa45ff7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/21d6ef64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/cfa61c33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rock Hill [](https://www.expedia.ca/Rock-Hill-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rock-Hill.h26598714.Hotel-Information) 9.0/10 Wonderful (1,091 reviews) "Yes the room was great and the breakfast was great, we will be back." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom CA $123 CA $136 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Rock-Hill-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rock-Hill.h26598714.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e6b95688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/0ca73b4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e4316a7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/27faffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Manning [](https://www.expedia.ca/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) 8.6/10 Excellent (1,001 reviews) "Staff great, room clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeanne CA $114 CA $126 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, Multiple Beds](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ea0c2078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ca4e1745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Florence [](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) 9.0/10 Wonderful (731 reviews) "Clean room, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $141 CA $158 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/5b536f5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/0d6ac1ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/8b9ec04b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) 8.8/10 Excellent (1,829 reviews) "Very friendly staff easy and safe check in." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlene CA $116 CA $130 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/e7174d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (1st Floor) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/f9691b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel in Florence [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) 8.6/10 Excellent (2,542 reviews) "Clean rooms, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suman CA $98 CA $109 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39480000/39474900/39474840/5bafe5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39480000/39474900/39474840/47c4a854.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/40000000/39480000/39474900/39474840/976555a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/40000000/39480000/39474900/39474840/56d0510c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Richburg by IHG [](https://www.expedia.ca/Rock-Hill-Hotels-Holiday-Inn-Express-Richburg.h39474840.Hotel-Information) 9.2/10 Wonderful (649 reviews) "Everything was enjoyable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George CA $150 CA $168 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Rock-Hill-Hotels-Holiday-Inn-Express-Richburg.h39474840.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-31&endDate=2026-02-01®ionId=6057938&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=CABIN) Cottages [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=COTTAGE) Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=APART_HOTEL) Houseboats [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=HOUSE_BOAT) Apartments [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=APARTMENT) Chalets [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=CHALET) Villas [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=VILLA) Condos [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=CONDO) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-19&d2=2026-04-19&lodging=VACATION_HOME) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Villas.d6057938-aaVillas.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Villas.d6057938-aaVillas.Travel-Guide-Accommodation) ## Top South Carolina Midlands Hotel Reviews ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "The room was clean and comfortable. The location was excellent and a perfect stop midway to Florida for some weary travelers." [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Tru By Hilton Columbia Downtown](https://images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "Clean room great beds " [](https://expedia.ca/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information) ![Tru by Hilton Rock Hill](https://images.trvl-media.com/lodging/43000000/42840000/42839800/42839781/b8c73c34_y.jpg) ### Tru by Hilton Rock Hill 10/10 Excellent "Clean, smelled great, very friendly staff & great breakfast" [](https://expedia.ca/Rock-Hill-Hotels-Tru-By-Hilton-Rock-Hill.h42839781.Hotel-Information) ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "The Graduate is our go to while in Columbia. Great stay." [](https://expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Variety of things to eat in the breakfast menu. Plenty of space to park my vehicle " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "Stay was nice had no issues. Very quiet. Great breakfast choices " [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Cambria Hotel Columbia Downtown The Vista](https://images.trvl-media.com/lodging/77000000/76600000/76599300/76599223/e2b9c83a_y.jpg) ### Cambria Hotel Columbia Downtown The Vista 10/10 Excellent "Yes" [](https://expedia.ca/Columbia-Hotels-Cambria-Hotel-Columbia-Downtown-The-Vista.h76599223.Hotel-Information) ![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson 10/10 Excellent "Rooms updated excellent appearance. Room ac had some extra vibration sound to deal with and bat vent fan a little noisy needed to be tightened up. Food good coffee and hot water not enough closer to warm. Arrival erson was more friendly and pleasant compared to check out person. Overall very impressed with room and stay." [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Excellent " [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ## Find out more about South Carolina Midlands ## South Carolina Midlands Villas information | Number of reviews | 22,178 | | ----------------- | -------- | | Accommodation | 0 Villas | | Lowest Price | CA $107 | | Highest Price | CA $189 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Allen University ](https://www.expedia.ca/Allen-University-Hotels.0-l6245638-0.Travel-Guide-Filter-Hotels) - [B&B in Arcadia Lakes ](https://www.expedia.ca/Arcadia-Lakes-Bed-And-Breakfast.d553248634998974994-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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