Title: South Carolina Midlands Vacation Home Rentals from CA $185: Search Top Private Vacation Homes for Rent | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.ca/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-02-06&endDate=2026-02-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 15 - May 17](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina Midlands vacation homes ![Smart TV](https://images.trvl-media.com/lodging/73000000/72690000/72689700/72689621/af14135a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/73000000/72690000/72689700/72689621/3e6edc10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/73000000/72690000/72689700/72689621/c754668a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/73000000/72690000/72689700/72689621/7170aea3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Turquoise Door in Town of Lexington [](https://www.expedia.ca/Lexington-Hotels-The-Turquoise-Door-In-Town-Of-Lexington.h72689621.Hotel-Information) Lexington 9.8/10 Exceptional (118 reviews) "Clean comfy rental near good restaurants, stores and Lake Murray damn. Centrally located. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sue S. CA $112 CA $388 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Lexington-Hotels-The-Turquoise-Door-In-Town-Of-Lexington.h72689621.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/73000000/72130000/72125100/72125029/w506h683x259y0-d0dc36b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/73000000/72130000/72125100/72125029/w506h683x259y0-7c735ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/73000000/72130000/72125100/72125029/67ee2258_edited_5bc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72130000/72125100/72125029/8db8afd1_edited_d288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden Cottage [](https://www.expedia.ca/Camden-Hotels-Camden-Cottage.h72125029.Hotel-Information) Camden 10/10 Exceptional (56 reviews) "Charming cottage on a beautiful property, super dog friendly and the owner is absolutely fantastic about responding to any questions or concerns, 100% would recommend and would stay again!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul H. CA $153 CA $264 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Camden-Hotels-Camden-Cottage.h72125029.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/80000000/79670000/79668500/79668437/c148491e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/80000000/79670000/79668500/79668437/d862c686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, printers](https://images.trvl-media.com/lodging/80000000/79670000/79668500/79668437/24f777ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, printers](https://images.trvl-media.com/lodging/80000000/79670000/79668500/79668437/e827b164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walking distance from one of South Carolina's top Medical centers. [](https://www.expedia.ca/Florence-Hotels-Walking-Distance-From-One-Of-South-Carolinas-Top-Medical-Centers.h79668437.Hotel-Information) Florence 9.8/10 Exceptional (42 reviews) "The house was beautiful. We would stay there again!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie L. CA $186 CA $323 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Florence-Hotels-Walking-Distance-From-One-Of-South-Carolinas-Top-Medical-Centers.h79668437.Hotel-Information) ![Smart TV, books](https://images.trvl-media.com/lodging/95000000/94800000/94795100/94795059/6cc0ea0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94800000/94795100/94795059/d976ad14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/95000000/94800000/94795100/94795059/1f22847e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, shampoo](https://images.trvl-media.com/lodging/95000000/94800000/94795100/94795059/bd28d6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peaceful Farm Getaway [](https://www.expedia.ca/Mullins-Hotels-Peaceful-Farm-Getaway.h94795059.Hotel-Information) Mullins 10/10 Exceptional (32 reviews) "Excellent Space. Loved It." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rodney CA $187 CA $292 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Mullins-Hotels-Peaceful-Farm-Getaway.h94795059.Hotel-Information) ![Smart TV, computer monitors](https://images.trvl-media.com/lodging/93000000/92810000/92806500/92806448/b2ce0693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, computer monitors](https://images.trvl-media.com/lodging/93000000/92810000/92806500/92806448/2b0cffeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/93000000/92810000/92806500/92806448/115f070a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/93000000/92810000/92806500/92806448/c7b580cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Restful Retreat | 1Bed/1Bth Home | King Bed | Luxury Bath [](https://www.expedia.ca/Rock-Hill-Hotels-The-Restful-Retreat-1Bed1Bth-Home-King-Bed-Luxury-Bath.h92806448.Hotel-Information) Old Town Rock Hill 9.8/10 Exceptional (9 reviews) "We enjoyed our stay. The house was clean and comfortable. It was convenient to the college. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carolyn P. CA $82 CA $428 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Rock-Hill-Hotels-The-Restful-Retreat-1Bed1Bth-Home-King-Bed-Luxury-Bath.h92806448.Hotel-Information) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/80000000/79210000/79209800/79209711/ab2ac921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/80000000/79210000/79209800/79209711/2a2ac9f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/80000000/79210000/79209800/79209711/3b88798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/80000000/79210000/79209800/79209711/w1008h1540x0y0-a7d452e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Last Resort at Martins Landing [](https://www.expedia.ca/Prosperity-Hotels-The-Last-Resort-At-Martins-Landing.h79209711.Hotel-Information) Hollands Landing 9.8/10 Exceptional (36 reviews) "Great place to stay for a Lake Murray get away!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Travis D. CA $156 CA $318 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Prosperity-Hotels-The-Last-Resort-At-Martins-Landing.h79209711.Hotel-Information) ![Smart TV, offices](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/c321e70e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/42ada466.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/431d124d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, offices](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/61772a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! [](https://www.expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) Santee 10/10 Exceptional (37 reviews) "Great house, very modern interior. Very clean. Close to town. We’ll definitely book the house on our fishing trip. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John H. CA $115 CA $426 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/73000000/72960000/72957100/72957050/7b7e316d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/73000000/72960000/72957100/72957050/99a914ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/73000000/72960000/72957100/72957050/efcd81d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/73000000/72960000/72957100/72957050/0695327c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boho Bliss |2 Bd/1Bth Top Floor Unit | King Beds | 5 Min. Walk to Winthrop [](https://www.expedia.ca/Rock-Hill-Hotels-Boho-Bliss-2-Bd1Bth-Top-Floor-Unit-2-King-Beds-5-Min-Walk-To-Winthrop.h72957050.Hotel-Information) Old Town Rock Hill 9.4/10 Exceptional (18 reviews) "My daughters loved the big comfy beds. Nice stay. Will visit this place again. Highly recommend. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa L. CA $101 CA $495 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Rock-Hill-Hotels-Boho-Bliss-2-Bd1Bth-Top-Floor-Unit-2-King-Beds-5-Min-Walk-To-Winthrop.h72957050.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108750000/108744800/108744751/372f30d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108750000/108744800/108744751/8d6c5a7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108750000/108744800/108744751/1a32ab0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108750000/108744800/108744751/0e61c35e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1972 Airstream luxury tiny living at it's best in Columbia near Lake Murray! [](https://www.expedia.ca/Columbia-Hotels-1972-Airstream-Luxury-Tiny-Living-At-Its-Best-In-Columbia-Near-Lake-Murray.h108744751.Hotel-Information) Columbia 9.8/10 Exceptional (30 reviews) "We enjoy our stay at this quaint quiet place. Loved the outdoor sitting area and the airstream was clean an cutely decorated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marian A. CA $149 CA $220 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Columbia-Hotels-1972-Airstream-Luxury-Tiny-Living-At-Its-Best-In-Columbia-Near-Lake-Murray.h108744751.Hotel-Information) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/76000000/75300000/75299000/75298908/23b3af6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/76000000/75300000/75299000/75298908/6fe0bb6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/76000000/75300000/75299000/75298908/fb3dae07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/76000000/75300000/75299000/75298908/969bc03f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Little Lemon Studio | King Bed | Office Space | Walk to Winthrop [](https://www.expedia.ca/Rock-Hill-Hotels-The-Little-Lemon-Studio-King-Bed-Office-Space-Walk-To-Winthrop.h75298908.Hotel-Information) Old Town Rock Hill 9.0/10 Wonderful (8 reviews) "Will return to this location, Very very well kept and nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos Mario CA $77 CA $403 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Rock-Hill-Hotels-The-Little-Lemon-Studio-King-Bed-Office-Space-Walk-To-Winthrop.h75298908.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/125000000/124200000/124199400/124199362/2dbcbdc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/125000000/124200000/124199400/124199362/100da31e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124200000/124199400/124199362/3011628a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124200000/124199400/124199362/06303571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bluebell Cottage - Renovated, No Checkout Instructions, Close to Downtown [](https://www.expedia.ca/Aiken-Hotels-Bluebell-Cottage-Renovated.h124199362.Hotel-Information) Aiken 10/10 Exceptional (1 review) "Our hosts were wonderful, touched base a few times to make sure had everything we needed. The home was more than we anticipated, and everything we could asked for and more. The yard gave our kids space to run around and get some energy out after our long journey. Thank you for making our first stay a wonderful experience. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) S M. CA $122 CA $405 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Aiken-Hotels-Bluebell-Cottage-Renovated.h124199362.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122390000/122388900/122388876/7d131b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, computer monitors](https://images.trvl-media.com/lodging/123000000/122390000/122388900/122388876/634d28bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/123000000/122390000/122388900/122388876/848c1a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/123000000/122390000/122388900/122388876/319892ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rock Hill Stay, Play, and Stroll [](https://www.expedia.ca/Rock-Hill-Hotels-Rock-Hill-Stay.h122388876.Hotel-Information) Old Town Rock Hill 10/10 Exceptional (3 reviews) "Cute and comfy! The jack-and-jill closet was great for our kids' sense of "security" (aka access to parents), too. Great location, too. Walking to Knowledge Perk n the mornings was a treat!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick A. CA $139 CA $185 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Rock-Hill-Hotels-Rock-Hill-Stay.h122388876.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/112000000/112000000/111993400/111993338/876e41e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/112000000/111993400/111993338/07159972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/112000000/111993400/111993338/e065578d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/112000000/111993400/111993338/d1a7898e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy and Quiet- Private Upstairs Duplex [](https://www.expedia.ca/Columbia-Hotels-Cozy-And-Quiet-Private-Upstairs-Duplex.h111993338.Hotel-Information) Columbia 10/10 Exceptional (10 reviews) "This duplex was the perfect place for our 3 night stay in SC. Very clean, comfortable and quite as promised. Anna was very nice and provided lots of information about the area. We were they for a show at the arena and when to one of the parks and the zoo. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terri T. CA $118 CA $225 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Columbia-Hotels-Cozy-And-Quiet-Private-Upstairs-Duplex.h111993338.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/124000000/123810000/123806000/123805969/7c0b03d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/124000000/123810000/123806000/123805969/1f7e5aae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/124000000/123810000/123806000/123805969/be0e7ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123810000/123806000/123805969/153943cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Landing at Wheat St.| 2Br in the heart of USC [](https://www.expedia.ca/Columbia-Hotels-The-Landing-At-Wheat-St-2Br-In-The-Heart-Of-USC.h123805969.Hotel-Information) Downtown Columbia CA $146 CA $466 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Columbia-Hotels-The-Landing-At-Wheat-St-2Br-In-The-Heart-Of-USC.h123805969.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/107000000/106280000/106270900/106270871/626e0f3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/107000000/106280000/106270900/106270871/a3bc2b0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106280000/106270900/106270871/28a9cc25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/107000000/106280000/106270900/106270871/1dad1381.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Double King 2bed/2 bath in Downtown Columbia! [](https://www.expedia.ca/Columbia-Hotels-Double-King-2bed2-Bath-In-Downtown-Columbia.h106270871.Hotel-Information) Columbia 9.8/10 Exceptional (8 reviews) "It was perfect and was what was needed for our little get away " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rickey N. CA $142 CA $548 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Columbia-Hotels-Double-King-2bed2-Bath-In-Downtown-Columbia.h106270871.Hotel-Information) ![Smart TV, books](https://images.trvl-media.com/lodging/89000000/88420000/88412500/88412464/74f57715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88420000/88412500/88412464/7158e2f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88420000/88412500/88412464/c1108401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88420000/88412500/88412464/24b230bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fun House/King Bed - Close to Town/Full of Entertainment! [](https://www.expedia.ca/Aiken-Hotels-NEWFun-House-Close-To-TownFull-Of-Entertainment.h88412464.Hotel-Information) Aiken 10/10 Exceptional (43 reviews) "House was very clean! Lots to do! Had an enjoyable stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara M. CA $175 CA $507 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Aiken-Hotels-NEWFun-House-Close-To-TownFull-Of-Entertainment.h88412464.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/92000000/91840000/91839800/91839762/be87065f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91840000/91839800/91839762/e940cb3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91840000/91839800/91839762/w505h683x260y0-4db9bc66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/92000000/91840000/91839800/91839762/1104cd0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Carriage House Suite on the Lake. [](https://www.expedia.ca/Fort-Mill-Hotels-NEW-Luxury-Carriage-House-Suite-On-The-Lake.h91839762.Hotel-Information) Fort Mill 10/10 Exceptional (17 reviews) "Lovely home in quiet neighborhood with stunning views. Can’t wait to visit again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie A. CA $191 CA $243 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Fort-Mill-Hotels-NEW-Luxury-Carriage-House-Suite-On-The-Lake.h91839762.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95130000/95125900/95125824/6400922f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/96000000/95130000/95125900/95125824/af6b0cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/95130000/95125900/95125824/1b08770a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95130000/95125900/95125824/w1024h678x0y3-2f728af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Large late1800's home within walking distance to Opera House and downtown. [](https://www.expedia.ca/Newberry-Hotels-Large-Late1800s-Home-Within-Walking-Distance-To-Opera-House-And-Downtown.h95125824.Hotel-Information) Newberry 9.8/10 Exceptional (38 reviews) "The house worked perfectly for us while we worked in Newberry. Unfortunately, we worked long days so we didn’t get as much time to enjoy it as we could." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dayna J. CA $187 CA $487 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Newberry-Hotels-Large-Late1800s-Home-Within-Walking-Distance-To-Opera-House-And-Downtown.h95125824.Hotel-Information) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/91000000/90360000/90353900/90353835/8a812fae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, offices](https://images.trvl-media.com/lodging/91000000/90360000/90353900/90353835/b06ca267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90360000/90353900/90353835/114f7fef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90360000/90353900/90353835/b756106a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunshine BNB in Downtown Cola- walk to 5 Parks! [](https://www.expedia.ca/Columbia-Hotels-3-Bed-With-Triple-Bunk-Bed-Perfect-For-Kids-In-Downtown-Columbia.h90353835.Hotel-Information) Rosewood 9.4/10 Exceptional (16 reviews) "This beautifully cozy home was such a wonderful stay. Everything was easy to find and the rooms were so cozy. Food choices were close by and its not too far from in town areas." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chasity B. CA $153 CA $589 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Columbia-Hotels-3-Bed-With-Triple-Bunk-Bed-Perfect-For-Kids-In-Downtown-Columbia.h90353835.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/112000000/111920000/111910100/111910025/d8c353af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, foosball, books](https://images.trvl-media.com/lodging/112000000/111920000/111910100/111910025/bce3437b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/112000000/111920000/111910100/111910025/89327cc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/112000000/111920000/111910100/111910025/74ae4d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aralia-5Min. to Williams-Brice/10Min. to Ft.Jackson [](https://www.expedia.ca/Columbia-Hotels-Aralia-5Min-To-Williams-Brice10Mins-To-FtJackson.h111910025.Hotel-Information) Rosewood 9.8/10 Exceptional (7 reviews) "Clean and nice for our family to visit and relax after long days." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer v. CA $160 CA $503 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Columbia-Hotels-Aralia-5Min-To-Williams-Brice10Mins-To-FtJackson.h111910025.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-03&endDate=2026-02-04®ionId=6057938&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=CABIN) Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=APART_HOTEL) Apartments [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=APARTMENT) Villas [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=VILLA) Condos [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=CONDO) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=VACATION_HOME) Cottages [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=COTTAGE) Houseboats [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.ca/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America®ionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Private-Vacation-Homes.d6057938-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Private-Vacation-Homes.d6057938-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top South Carolina Midlands Hotel Reviews ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Everything was so nice and clean. Bed was comfy. Staff was great" [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Wyndham Garden Columbia/Ft. Jackson](https://images.trvl-media.com/lodging/78000000/77820000/77814700/77814689/e6cbdb45_y.jpg) ### Wyndham Garden Columbia/Ft. Jackson 10/10 Excellent "Clean room very quiet will give it a thumbs up and if I ever go back to South Carolina I will stay again " [](https://expedia.ca/Columbia-Hotels-Hotel-Columbia-Inn-Suites.h77814689.Hotel-Information) ![Hyatt Place Columbia/Downtown/The Vista](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690567/c2bace01_y.jpg) ### Hyatt Place Columbia/Downtown/The Vista 10/10 Excellent "The staff was very friendly. Loved the bar and food. Great location for Gamecocks basketball games " [](https://expedia.ca/Columbia-Hotels-Hyatt-Place-ColumbiaDowntownThe-Vista.h8690567.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 10/10 Excellent "The outside of the building is nothing to look at, but the room was modern, clean, had good bathrooms, was spacious. Had a larger refrigerator and a microwave. Very comfortable for an overnight stay. The price was great too" [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "Staff was courteous and room was clean. I would definitely stay here again! " [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "The room was clean and comfortable. The location was excellent and a perfect stop midway to Florida for some weary travelers." [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Tru By Hilton Columbia Downtown](https://images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "Clean room great beds " [](https://expedia.ca/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information) ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "The Graduate is our go to while in Columbia. Great stay." [](https://expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "Extremely clean room very friendly staff breakfast had a great variety" [](https://expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ## Find out more about South Carolina Midlands ## South Carolina Midlands Vacation Homes information | Number of reviews | 521 | | ----------------- | ------------------ | | Accommodation | 837 Vacation Homes | | Lowest Price | CA $185 | | Highest Price | CA $589 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Allen University ](https://www.expedia.ca/Allen-University-Hotels.0-l6245638-0.Travel-Guide-Filter-Hotels) - [B&B in Arcadia Lakes ](https://www.expedia.ca/Arcadia-Lakes-Bed-And-Breakfast.d553248634998974994-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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