Title: Hotels by La Quinta Inn & Suites in South Carolina Midlands from CA $122 | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.ca/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by La Quinta Inn & Suites in South Carolina Midlands from CA $122 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 26 - Nov 27](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-26&endDate=2025-11-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 27 - Nov 28](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-27&endDate=2025-11-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Carolina Midlands La Quinta Inn & Suites Hotels ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/d2e2f4b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/6255d302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/0d6ac1ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson Columbia 8.8/10 Excellent (1759) "Very nice staff and a great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jefferson CA $123 CA $138 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/33d87b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/32cfa9c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/470d616b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Columbia SE / Fort Jackson Columbia 7.6/10 Good (1011) "Great breakfast and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jean CA $109 CA $122 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/26a37b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/cfa61c33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/7d3e14d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/27000000/26600000/26598800/26598714/aa45ff7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rock Hill Rock Hill 8.8/10 Excellent (1071) "Great breakfast options, nice room and comfortable bed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $119 CA $132 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Rock-Hill-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rock-Hill.h26598714.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/38be55ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f63ba12c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/c105915a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence Florence 8.0/10 Very good (1690) "Friendly staff, clean just what I was looking for!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradford CA $138 CA $154 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11®ionId=6057938&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Hotels-La-Quinta-Inn-Suites.0-0-d6057938--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Hotels-La-Quinta-Inn-Suites.0-0-d6057938--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top South Carolina Midlands Hotel Reviews ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "The room was very clean!" [](https://expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "Good stay. Clean room. Temperature well-controlled by ac unit. Kids enjoyed breakfast. Friendly service at check-in and check-out." [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "Great hotel! Super clean and staff is so friendly." [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "Room was clean, bed was OK (too firm for our liking), breakfast was ok. Very nice place to stay overnight during our travels. " [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Tru by Hilton Rock Hill](https://images.trvl-media.com/lodging/43000000/42840000/42839800/42839781/b8c73c34_y.jpg) ### Tru by Hilton Rock Hill 10/10 Excellent "Very modern, clean, and lots of amenities. We will definitely stay here again." [](https://expedia.ca/Rock-Hill-Hotels-Tru-By-Hilton-Rock-Hill.h42839781.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Love everything " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Cambria Hotel Columbia Downtown The Vista](https://images.trvl-media.com/lodging/77000000/76600000/76599300/76599223/e2b9c83a_y.jpg) ### Cambria Hotel Columbia Downtown The Vista 10/10 Excellent "Breakfast was good and hotel felt modernized!" [](https://expedia.ca/Columbia-Hotels-Cambria-Hotel-Columbia-Downtown-The-Vista.h76599223.Hotel-Information) ![Baymont by Wyndham Columbia Fort Jackson](https://images.trvl-media.com/lodging/1000000/580000/574500/574461/c68af965_y.jpg) ### Baymont by Wyndham Columbia Fort Jackson 10/10 Excellent "The rooms were clean, staff was great, they let us stay in our cold room u" [](https://expedia.ca/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Fort-Jackson.h574461.Hotel-Information) ![Tru By Hilton Columbia Greystone](https://images.trvl-media.com/lodging/40000000/39640000/39637100/39637010/38e4995a_y.jpg) ### Tru By Hilton Columbia Greystone 10/10 Excellent "The staff is friendly, the room is clean, and there is always good coffee in the lobby!" 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[Visit Lake Carolina](https://www.expedia.ca/Columbia-Lake-Carolina.dx553248635976478007) - [Visit Forest Acres](https://www.expedia.ca/Forest-Acres.dx553248634998960051) - [Visit Killian](https://www.expedia.ca/Killian.dx553248635975872238) - [Avis Rental Cars in Blythewood](https://www.expedia.ca/Avis-Car-Rentals-In-Blythewood.d180657-c41.Car-Rental-Guide-Suppliers) - [Car rental Elgin](https://www.expedia.ca/Car-Rentals-In-Elgin.d6051125.Car-Rental-Guide) - [Blythewood Vacation Rentals](https://www.expedia.ca/Blythewood-Vacation-Rentals.d180657.Travel-Guide-VacationRentals) - [Book La Quinta Inn & Suites in South Carolina Midlands on Expedia.com](https://www.expedia.com/South-Carolina-Midlands-Hotels-La-Quinta-Inn-Suites.0-0-d6057938--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)