Title: Book the Best BUSINESS Hotels in South Carolina Midlands in 2026 | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.ca/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in South Carolina Midlands, SC from CA $97 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Midlands Business Hotels Tonight [Dec 2 - Dec 3](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top South Carolina Midlands Business Hotels ![Breakfast and dinner served](https://images.trvl-media.com/lodging/18000000/17370000/17370000/17369973/9eb183a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17370000/17370000/17369973/e288e3a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17370000/17370000/17369973/485b8fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17370000/17370000/17369973/7f5dfdba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Columbia Cayce Cayce 9.0/10 Wonderful (649) "Quite place with small restraunt and bar" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jordan CA $141 CA $157 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Columbia-Hotels-Courtyard-By-Marriott-Columbia-Cayce.h17369973.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee Santee 8.0/10 Very good (1405) "The best stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terez CA $112 CA $124 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/c7afe694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/22e67acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/0ea8f0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area Florence 9.2/10 Wonderful (1171) "Enjoyed our stay there. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathy CA $138 CA $155 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/ebea43b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence Florence 8.8/10 Excellent (2465) "Room clean, nice hot water in tub and friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $87 CA $97 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/bee831df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/cbc9a37d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown Florence 8.8/10 Excellent (1014) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michaelle CA $140 CA $157 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/a4197341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/7b01c436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg Orangeburg 9.2/10 Wonderful (1010) "Staff was friendly, room was clean and quiet. recommend this property." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet CA $144 CA $160 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/22eb9cd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/a2c60bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/16ca8b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 Florence 9.0/10 Wonderful (807) "Clean room, courteous staff and easy access to and from highway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe CA $144 CA $162 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/0f2c01c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/45d8f751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/0a695ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Columbia/Harbison Columbia 9.0/10 Wonderful (1852) "great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ben CA $111 CA $124 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/24000000/23710000/23704200/23704165/2c0ae9c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23710000/23704200/23704165/3d870b01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/24000000/23710000/23704200/23704165/7a53262d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/24000000/23710000/23704200/23704165/ac69232d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Charlotte - Ballantyne by IHG Ballantyne 8.8/10 Excellent (1024) "Room was clean staff was pleasant close to lots of stores and food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $85 CA $98 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Charlotte-Hotels-Holiday-Inn-Express-Suites-Charlotte-Ballantyne.h23704165.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0b9239a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/51d8f371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC Florence 9.0/10 Wonderful (2217) "Friendly and efficient staff and a nice room for my overnight stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carole CA $132 CA $147 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=6057938&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_6057938) ## Top South Carolina Midlands Hotel Reviews ![Baymont by Wyndham Columbia Fort Jackson](https://images.trvl-media.com/lodging/1000000/580000/574500/574461/c68af965_y.jpg) ### Baymont by Wyndham Columbia Fort Jackson 10/10 Excellent "Yes" [](https://expedia.ca/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Fort-Jackson.h574461.Hotel-Information) ![Courtyard by Marriott Columbia Downtown at USC](https://images.trvl-media.com/lodging/1000000/10000/2300/2289/w3996h2667x0y0-8dd1e3e0_y.jpg) ### Courtyard by Marriott Columbia Downtown at USC 10/10 Excellent "Fast service and great perks!" [](https://expedia.ca/Columbia-Hotels-Courtyard-By-Marriott-Columbia-Downtown-At-USC.h2289.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "We stay here on our way to our vacation property every year. The staff is courteous, professional & always helpful. The rooms are nice, beds comfy, & it’s clean. " [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Exelent" [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Clean room and my vehicle was safe. A+" [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![ La Quinta Inn by Wyndham Columbia NE/Fort Jackson](https://images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50_y.jpg) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson 10/10 Excellent "Clean room staff was great housekeeping wonderful " [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Sleep Inn Columbia](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf_y.jpg) ### Sleep Inn Columbia 10/10 Excellent "Staff was wonderful and the room was clean and had all necessary amenities included " [](https://expedia.ca/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information) ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "Awesome location!" [](https://expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, SC](https://images.trvl-media.com/lodging/1000000/210000/202900/202867/04e820c9_y.jpg) ### Country Inn & Suites by Radisson, Columbia, SC 10/10 Excellent "Will stay again" [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h202867.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in South Carolina Midlands cost? > You can expect to pay between CA $97 and CA $162 per night for business-friendly hotels in South Carolina Midlands. Epic deals on stays that cater to work-related guests are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the best business-friendly hotels in South Carolina Midlands? > There are multiple business-friendly hotels in South Carolina Midlands with a total average guest review rating of 8.7, so you're sure to discover a place that suits your needs. Basing yourself in Columbia? [Staybridge Suites Columbia, an IHG Hotel](https://www.expedia.ca/Columbia-Hotels-Staybridge-Suites-Columbia.h2246543.Hotel-Information) is popular with corporate travellers. This 3-stars option offers conveniences like a barbecue grill and a swimming pool. [Hampton Inn Columbia I-26/Harbison Blvd.](https://www.expedia.ca/Columbia-Hotels-Hampton-Inn-Columbia-I-26Harbison-Blvd.h42875.Hotel-Information) also scores top marks from business guests. Take advantage of complimentary use of a nearby fitness centre and a swimming pool at this 2.5-stars property in Columbia. ### How many business-friendly hotels are there in South Carolina Midlands? > When your next meeting or networking event takes you someplace in South Carolina Midlands, you'll have 268 business-friendly hotels to choose from. ### What are the best cheap business-friendly hotels in South Carolina Midlands? > That depends on where in South Carolina Midlands your journey is taking you. If your destination is Columbia, [Hampton Inn Columbia I-26/Harbison Blvd.](https://www.expedia.ca/Columbia-Hotels-Hampton-Inn-Columbia-I-26Harbison-Blvd.h42875.Hotel-Information) meets the needs of business travellers at an affordable price. A terrace and pool sun loungers are among its many conveniences. On your way to Florence? Consider staying at [Hampton Inn & Suites Florence Centre](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information). A swimming pool and WiFi help make this cheaper property a top choice for corporate guests. Business-friendly hotels start from CA $97 a night, so your next work trip doesn't have to cost a lot. Want to see the sights of South Carolina Midlands without the high admission prices? Take time out from your business commitments to visit free attractions like [Trinity Episcopal Cathedral](https://www.expedia.ca/Trinity-Episcopal-Cathedral-Downtown-Columbia.d553248621532657318.Vacation-Attraction) in Columbia. Florence also has plenty of things to do that don't cost anything, including [Florence Museum](https://www.expedia.ca/Florence-Museum-Florence.d6162137.Vacation-Attraction). This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the top business-friendly motels in South Carolina Midlands? > If your South Carolina Midlands business visit includes Columbia, check in to [Days Inn by Wyndham Columbia](https://www.expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Columbia.h532027.Hotel-Information). Around 6 kilometres northwest of the downtown area and offering a swimming pool and a terrace, it's popular with corporate guests. Alternatively, work comfortably from [America's Best Inn Columbia](https://www.expedia.ca/Columbia-Hotels-Americas-Best-Inn-Columbia.h18676.Hotel-Information). A balcony and front desk services are among the conveniences at this property, located around 6 kilometres northwest of the centre of Columbia.There's no shortage of things to keep you entertained during your downtime in Columbia. [Riverbanks Zoo and Garden](https://www.expedia.ca/Riverbanks-Zoo-And-Garden-Columbia.d6082673.Vacation-Attraction) and [Township Auditorium](https://www.expedia.ca/Township-Auditorium-Downtown-Columbia.d553248621532657321.Vacation-Attraction) should be on your travel itinerary. ### Are there any family-friendly hotels in South Carolina Midlands that are also business friendly? > If you're travelling for business in South Carolina Midlands and bringing family along with you, Expedia will help you find a cozy and convenient stay. [Hampton Inn Columbia I-26/Harbison Blvd.](https://www.expedia.ca/Columbia-Hotels-Hampton-Inn-Columbia-I-26Harbison-Blvd.h42875.Hotel-Information) in Columbia is the perfect option for those juggling work and pleasure. This 2.5-stars hotel offers all the amenities you need, like a playground and complimentary breakfast. [Holiday Inn Columbia - Downtown, an IHG Hotel](https://www.expedia.ca/Columbia-Hotels-Holiday-Inn-Columbia-Downtown.h36264221.Hotel-Information) is another good choice in Columbia. You'll be able to combine corporate travel and quality time with your family at this 3-stars property. Laundry facilities and housekeeping services are among the numerous conveniences here. There are plenty of exciting things to do with your little travellers in Columbia. [Riverbanks Zoo and Garden](https://www.expedia.ca/Riverbanks-Zoo-And-Garden-Columbia.d6082673.Vacation-Attraction) and [South Carolina State Museum](https://www.expedia.ca/South-Carolina-State-Museum-Downtown-Columbia.d6082675.Vacation-Attraction) offer a memorable day out. ### Why book your business-friendly hotel in South Carolina Midlands with Expedia? > Expedia is here to help you find a fabulous business-friendly hotel when work takes you out of town. From free WiFi and parking to on-site cafés and restaurants, our stays have the things you need to get the job done. ### How can I find cheap business-friendly hotels in South Carolina Midlands? > Expedia can help you narrow down your search for cheap business-friendly hotels in South Carolina Midlands. Simply go to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work effectively and comfortably, like free WiFi and included breakfast. You can also choose your preferred star rating and budget to keep costs to a minimum. ### What is there to do in South Carolina Midlands near my business-friendly hotel? > You'll discover plenty of things to keep you entertained in South Carolina Midlands. If you're making your way to Columbia, drop by [Riverbanks Zoo and Garden](https://www.expedia.ca/Riverbanks-Zoo-And-Garden-Columbia.d6082673.Vacation-Attraction), [Township Auditorium](https://www.expedia.ca/Township-Auditorium-Downtown-Columbia.d553248621532657321.Vacation-Attraction) and [South Carolina State Museum](https://www.expedia.ca/South-Carolina-State-Museum-Downtown-Columbia.d6082675.Vacation-Attraction). Packing your suitcases for Florence? [Florence Museum](https://www.expedia.ca/Florence-Museum-Florence.d6162137.Vacation-Attraction), [Mcleod Regional Medical Centre](https://www.expedia.ca/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) and [Florence National Cemetery](https://www.expedia.ca/Florence-National-Cemetery-Florence.d553248621532657341.Vacation-Attraction) are top attractions here. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Allen University](https://www.expedia.ca/Allen-University-Hotels.0-l6245638-0.Travel-Guide-Filter-Hotels) - [B&B in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Bed-And-Breakfast.d553248634998974994-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Guest-Houses.d553248634998974994-aaGuestHouses.Travel-Guide-Accommodation) - [Arcadia Lakes Hotels](https://www.expedia.ca/Arcadia-Lakes-Hotels.d553248634998974994.Travel-Guide-Hotels) - [Inns in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Inns.d553248634998974994-aaInns.Travel-Guide-Accommodation) - [Hotels near Benedict College](https://www.expedia.ca/Benedict-College-Hotels.0-l553248635056398076-0.Travel-Guide-Filter-Hotels) - [Apartments in Blythewood](https://www.expedia.ca/Blythewood-Apartments.d180657-aaApartments.Travel-Guide-Accommodation) - [B&B in Blythewood](https://www.expedia.ca/Blythewood-Bed-And-Breakfast.d180657-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Casino Hotels in Blythewood](https://www.expedia.ca/Blythewood-Hotels-Casino-Hotel.0-0-d180657-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Blythewood](https://www.expedia.ca/Blythewood-Hotels-Cheap-Hotels.0-0-d180657-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Blythewood](https://www.expedia.ca/Blythewood-Hotels-Luxury-Hotel.0-0-d180657-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Blythewood](https://www.expedia.ca/Blythewood-Hotels-Pet-Friendly-Hotel.0-0-d180657-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Blythewood Hotels](https://www.expedia.ca/Blythewood-Hotels.d180657.Travel-Guide-Hotels) - [Vacation Homes in Blythewood](https://www.expedia.ca/Blythewood-Private-Vacation-Homes.d180657-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Guest Houses in Cedar Creek](https://www.expedia.ca/Cedar-Creek-Guest-Houses.d553248635975849474-aaGuestHouses.Travel-Guide-Accommodation) - [Columbia Hotels](https://www.expedia.ca/Columbia-Hotels.d764.Travel-Guide-Hotels) - [Hotels near Columbia Place Mall](https://www.expedia.ca/Columbia-Place-Mall-Hotels.0-l6157985-0.Travel-Guide-Filter-Hotels) - [B&B in Dentsville](https://www.expedia.ca/Dentsville-Bed-And-Breakfast.d6345142-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Dentsville](https://www.expedia.ca/Dentsville-Hotels-Cheap-Hotels.0-0-d6345142-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Dentsville](https://www.expedia.ca/Dentsville-Hotels-Hotel-With-Pool.0-0-d6345142-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Dentsville](https://www.expedia.ca/Dentsville-Hotels-Hotels-With-Indoor-Pool.0-0-d6345142-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Dentsville](https://www.expedia.ca/Dentsville-Hotels-Pet-Friendly-Hotel.0-0-d6345142-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Dentsville Hotels](https://www.expedia.ca/Dentsville-Hotels.d6345142.Travel-Guide-Hotels) - [Vacation Homes in Dentsville](https://www.expedia.ca/Dentsville-Private-Vacation-Homes.d6345142-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Hotels with a Pool in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - [Hotels with Free Airport Shuttle in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Airport-Shuttle.0-0-d242-tHotelswithFreeAirportShuttle.Hotel-Filter-Destinations) - [Hotels with Free Breakfast in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Breakfast.0-0-d242-tHotelswithFreeBreakfast.Hotel-Filter-Destinations) - [Hotels with Free Parking in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Parking.0-0-d242-tHotelswithFreeParking.Hotel-Filter-Destinations) - [Hotels with Tennis Courts in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Tennis-Courts.0-0-d242-tHotelswithTennisCourts.Hotel-Filter-Destinations) - [Lgbt Friendly Hotels in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-LGBT-Friendly-Hotel.0-0-d242-tLGBTFriendlyHotel.Hotel-Filter-Destinations) - [Scuba Diving Hotels in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Scuba-Diving-Vacations.0-0-d242-tscubadivingvacations.Hotel-Filter-Destinations) - [Aparthotels in Eau Claire](https://www.expedia.ca/Eau-Claire-Apart-Hotels.d6344268-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Eau Claire](https://www.expedia.ca/Eau-Claire-Bed-And-Breakfast.d6344268-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Eau Claire](https://www.expedia.ca/Eau-Claire-Guest-Houses.d6344268-aaGuestHouses.Travel-Guide-Accommodation) - [Eau Claire Hotels](https://www.expedia.ca/Eau-Claire-Hotels.d6344268.Travel-Guide-Hotels) - [Inns in Eau Claire](https://www.expedia.ca/Eau-Claire-Inns.d6344268-aaInns.Travel-Guide-Accommodation) - [Motels in Eau Claire](https://www.expedia.ca/Eau-Claire-Motels.d6344268-aaMotels.Travel-Guide-Accommodation) - [Vacation Homes in Eau Claire](https://www.expedia.ca/Eau-Claire-Private-Vacation-Homes.d6344268-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [B&B in Elgin](https://www.expedia.ca/Elgin-Bed-And-Breakfast.d6051125-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Elgin](https://www.expedia.ca/Elgin-Cabins.d6051125-aaCabins.Travel-Guide-Accommodation) - [Castles in Elgin](https://www.expedia.ca/Elgin-Castles.d6051125-aaCastles.Travel-Guide-Accommodation) - [Guest Houses in Elgin](https://www.expedia.ca/Elgin-Guest-Houses.d6051125-aaGuestHouses.Travel-Guide-Accommodation) - [Cheap Hotels in Elgin](https://www.expedia.ca/Elgin-Hotels-Cheap-Hotels.0-0-d6051125-tCheapHotels.Travel-Guide-Filter-Hotels) - [Elgin Hotels](https://www.expedia.ca/Elgin-Hotels.d6051125.Travel-Guide-Hotels) - [Inns in Elgin](https://www.expedia.ca/Elgin-Inns.d6051125-aaInns.Travel-Guide-Accommodation) - [Farmstay in Forest Acres](https://www.expedia.ca/Forest-Acres-Agritourism.d553248634998960051-aaAgritourism.Travel-Guide-Accommodation) - [Cheap Hotels in Forest Acres](https://www.expedia.ca/Forest-Acres-Hotels-Cheap-Hotels.0-0-d553248634998960051-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Forest Acres](https://www.expedia.ca/Forest-Acres-Hotels-Luxury-Hotel.0-0-d553248634998960051-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Forest Acres Hotels](https://www.expedia.ca/Forest-Acres-Hotels.d553248634998960051.Travel-Guide-Hotels) - [Hotels near Fort Jackson](https://www.expedia.ca/Fort-Jackson-Hotels.0-l6145263-0.Travel-Guide-Filter-Hotels) - [Hotels near Hilton Field](https://www.expedia.ca/Hilton-Field-Hotels.0-l553248628697942700-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Killian](https://www.expedia.ca/Killian-Hotels-Cheap-Hotels.0-0-d553248635975872238-tCheapHotels.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Killian](https://www.expedia.ca/Killian-Hotels-LGBT-Friendly-Hotel.0-0-d553248635975872238-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Killian Hotels](https://www.expedia.ca/Killian-Hotels.d553248635975872238.Travel-Guide-Hotels) - [Pet-Friendly Hotels in Lake Carolina](https://www.expedia.ca/Lake-Carolina-Columbia-Hotels-Pet-Friendly-Hotel.0-n553248635976478007-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Lake Carolina](https://www.expedia.ca/Lake-Carolina-Columbia-Hotels-Spa-Hotel.0-n553248635976478007-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Lake Carolina Hotels](https://www.expedia.ca/Lake-Carolina-Columbia-Hotels.0-n553248635976478007-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Lyon Street](https://www.expedia.ca/Lyon-Street-Columbia-Hotels-Boutique-Hotel.0-n896347438500220928-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Lyon Street](https://www.expedia.ca/Lyon-Street-Columbia-Hotels-Motel-6.0-n896347438500220928-0--bMotel6.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Lyon Street](https://www.expedia.ca/Lyon-Street-Columbia-Hotels-Red-Roof-Inn.0-n896347438500220928-0--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Casino Hotels in Melrose Heights](https://www.expedia.ca/Melrose-Heights-Columbia-Hotels-Casino-Hotel.0-n896347640074293248-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Old Shandon](https://www.expedia.ca/Old-Shandon-Columbia-Hotels-Spa-Hotel.0-n6346757-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotels near Palmetto Health Richland Hospital](https://www.expedia.ca/Palmetto-Health-Richland-Hospital-Hotels.0-l6220759-0.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Pinehurst](https://www.expedia.ca/Pinehurst-Columbia-Hotels-Hotels-With-Free-Breakfast.0-n896346174504779776-0-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Rosewood](https://www.expedia.ca/Rosewood-Columbia-Hotels-Adults-Only-Resorts.0-n553248635976478188-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Spa Hotels in Rosewood](https://www.expedia.ca/Rosewood-Columbia-Hotels-Spa-Hotel.0-n553248635976478188-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Rosewood](https://www.expedia.ca/Rosewood-Columbia-Hotels-Wedding-Hotels.0-n553248635976478188-0-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Rosewood Hotels](https://www.expedia.ca/Rosewood-Columbia-Hotels.0-n553248635976478188-0.Travel-Guide-Filter-Hotels) - [Sandwood Hotels](https://www.expedia.ca/Sandwood-Hotels.d553248635975866528.Travel-Guide-Hotels) - [Hotels near Segra Park](https://www.expedia.ca/Segra-Park-Hotels.0-l553248635997958829-0.Travel-Guide-Filter-Hotels) - [Hotels near Sesquicentennial State Park](https://www.expedia.ca/Sesquicentennial-State-Park-Hotels.0-l6157980-0.Travel-Guide-Filter-Hotels) - [Shandon Hotels](https://www.expedia.ca/Shandon-Columbia-Hotels.0-n553248635976478434-0.Travel-Guide-Filter-Hotels) - [Hotels near Township Auditorium](https://www.expedia.ca/Township-Auditorium-Hotels.0-l553248621532657321-0.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Waverly](https://www.expedia.ca/Waverly-Columbia-Hotels-Beach-Hotel.0-n6346761-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Waverly](https://www.expedia.ca/Waverly-Columbia-Hotels-Hotel-With-Early-Check-In.0-n6346761-0-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Waverly](https://www.expedia.ca/Waverly-Columbia-Hotels-Oceanfront-Hotels.0-n6346761-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Waverly Hotels](https://www.expedia.ca/Waverly-Columbia-Hotels.0-n6346761-0.Travel-Guide-Filter-Hotels) - [Farmstay in Woodfield](https://www.expedia.ca/Woodfield-Agritourism.d6348005-aaAgritourism.Travel-Guide-Accommodation) - [Apartments in Woodfield](https://www.expedia.ca/Woodfield-Apartments.d6348005-aaApartments.Travel-Guide-Accommodation) - [B&B in Woodfield](https://www.expedia.ca/Woodfield-Bed-And-Breakfast.d6348005-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Woodfield](https://www.expedia.ca/Woodfield-Hotels-Beach-Hotel.0-0-d6348005-tBeachHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Woodfield](https://www.expedia.ca/Woodfield-Hotels-Cheap-Hotels.0-0-d6348005-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Woodfield](https://www.expedia.ca/Woodfield-Hotels-Golf-Hotel.0-0-d6348005-tGolfHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Woodfield](https://www.expedia.ca/Woodfield-Hotels-Luxury-Hotel.0-0-d6348005-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Woodfield](https://www.expedia.ca/Woodfield-Hotels-Pet-Friendly-Hotel.0-0-d6348005-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Woodfield Hotels](https://www.expedia.ca/Woodfield-Hotels.d6348005.Travel-Guide-Hotels) - [Inns in Woodfield](https://www.expedia.ca/Woodfield-Inns.d6348005-aaInns.Travel-Guide-Accommodation) - [Flights to Blythewood](https://www.expedia.ca/Cheap-Flights-To-Blythewood.d180657.Travel-Guide-Flights) - [Flights to Columbia](https://www.expedia.ca/Cheap-Flights-To-Columbia.d764.Travel-Guide-Flights) - [Flights to South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina.d242.Flight-Destinations) - [Flights from Elgin](https://www.expedia.ca/lp/flights/6051125/flights-from-elgin) - [Allen University](https://www.expedia.ca/Allen-University-Downtown-Columbia.d6245638.Vacation-Attraction) - [Visit Blythewood](https://www.expedia.ca/Blythewood.dx180657) - [Visit Lake Carolina](https://www.expedia.ca/Columbia-Lake-Carolina.dx553248635976478007) - [Visit Forest Acres](https://www.expedia.ca/Forest-Acres.dx553248634998960051) - [Visit Killian](https://www.expedia.ca/Killian.dx553248635975872238) - [Avis Rental Cars in Blythewood](https://www.expedia.ca/Avis-Car-Rentals-In-Blythewood.d180657-c41.Car-Rental-Guide-Suppliers) - [Car rental Elgin](https://www.expedia.ca/Car-Rentals-In-Elgin.d6051125.Car-Rental-Guide) - [Blythewood Vacation Rentals](https://www.expedia.ca/Blythewood-Vacation-Rentals.d180657.Travel-Guide-VacationRentals) - [Book Business Hotels in South Carolina Midlands on Expedia.com](https://www.expedia.com/South-Carolina-Midlands-Hotels-Business-Hotel.0-0-d6057938-tBusinessHotel.Travel-Guide-Filter-Hotels)