Title: South Carolina Midlands Guest Houses | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.ca/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/183000/183997-State-House.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in South Carolina Midlands ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-17&endDate=2025-10-19&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-07&endDate=2025-11-09&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-12-05&endDate=2025-12-07&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select South Carolina Midlands Guest Houses ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/27000000/26610000/26603100/26603084/53422b43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/27000000/26610000/26603100/26603084/7f3da249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26610000/26603100/26603084/0c253bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/27000000/26610000/26603100/26603084/be4b7b0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Burch's Carriage House Society Hill 9.8/10 Exceptional (30) "This pet friendly accomodation was perfect for my trip to South Carolina! Will definitely be booking this again on my next trip to the area." CA $119 CA $214 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Society-Hill-Hotels-Burchs-Carriage-House.h26603084.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/101000000/100670000/100666500/100666449/1a619b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100670000/100666500/100666449/24f1cf86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/101000000/100670000/100666500/100666449/651d6dac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100670000/100666500/100666449/4daf1448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wren\`s Nest | 1BR 2BA Guesthouse Earlewood 10/10 Exceptional (4) "Wonderful, well appointed, restful retreat. We stayed for USC Family weekend and found this to be convenient for getting to and from campus without too much traffic. Would definitely stay again. The outdoor setting is beautiful. Wish we had been around longer to enjoy it" CA $174 CA $398 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Columbia-Hotels-The-Wren-1BR-2BA-Guesthouse.h100666449.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111620000/111619300/111619253/d61c103b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, offices](https://images.trvl-media.com/lodging/112000000/111620000/111619300/111619253/7268081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111620000/111619300/111619253/9dd4c5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/112000000/111620000/111619300/111619253/a109e72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casita - COLA & Hot Tub Downtown Columbia 9.8/10 Exceptional (6) "Nice and quiet spot to relax and unwind." CA $162 CA $282 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Columbia-Hotels-Casita-COLA-Hot-Tub.h111619253.Hotel-Information) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100190000/100186000/100185994/9f077566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100190000/100186000/100185994/52ed3441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100190000/100186000/100185994/b3f5aa6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/101000000/100190000/100186000/100185994/4044fefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amazing Studio Guesthouse, in beautiful Columbia Lake community suburb. Lake Carolina 10/10 Exceptional (9) "We were in the area for a family wedding and this was the closest we could get to the venue area (about 15-20min north). It was a nice, quiet, clean spot to relax between the events. The bed was cozy and the kitchen was well-equipped. Our two-year-old loved the big projector screen for some morning Ms Rachel videos! ;) Raul was easy to communicate with and super helpful. Neighborhood is quiet and we enjoyed walks with our kiddo (sadly he didn't get much playtime at the park with everything going... CA $168 CA $219 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Columbia-Hotels-Amazing-Studio-Guesthouse.h100185994.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/71000000/70070000/70060600/70060537/e459bc7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/71000000/70070000/70060600/70060537/2aabbd2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70070000/70060600/70060537/9ea95753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/71000000/70070000/70060600/70060537/57359d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 818 Queen St · Relaxing Cozy Apartment in Downtown Cola Downtown Columbia 9.6/10 Exceptional (8) "We stayed here for family weekend at UofSC and it was perfect! Great location, safe area and very comfortable. Will definitely stay here again!" CA $130 CA $331 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Columbia-Hotels-818-Queen-St-Relaxing-Cozy-Apartment-In-Downtown-Cola.h70060537.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2490000/2480500/2480442/52a01cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City Room](https://images.trvl-media.com/lodging/3000000/2490000/2480500/2480442/5b0c51e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/3000000/2490000/2480500/2480442/cf019b3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/3000000/2490000/2480500/2480442/6218bff3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Queen Anne Inn Olde Town Augusta 8.0/10 Very good (88) "The property was close to theater venues and restaurant options. I felt safe in the neighborhood. The hosts were knowledgeable and accommodating. I will stay again " CA $210 CA $253 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Augusta-Hotels-The-Queen-Anne-Inn.h2480442.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/101000000/100390000/100387000/100386972/w1199h799x1y1-7cb15f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100390000/100387000/100386972/fed869a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100390000/100387000/100386972/eea0182d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/101000000/100390000/100387000/100386972/w1199h799x1y1-b7714f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 bedroom, 1 bathroom sleeps max 4 guests with the sleeping arrangements being a king bed and futon that sleeps 2 Summerville 10/10 Exceptional (5) "We loved this cottage and the location! The host was very responsive and helpful when we had questions. This location is perfectly located—great food and walking on the beautiful campus were so close." CA $91 CA $379 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Augusta-Hotels-1-Bedroom.h100386972.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/101000000/100390000/100387000/100386968/w1200h799x0y1-e9b19e72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100390000/100387000/100386968/f9a825c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100390000/100387000/100386968/w1200h799x0y1-308fe4ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100390000/100387000/100386968/07b11d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1 bed 1 bath home that sleeps max 4 guests with sleeping arrangements being a queen bed and a fold out couch that is queen sized. Summerville 9.0/10 Wonderful (4) "Property was very cozy and had everything I needed for a weekend work stay. Super close to restaurants and grocery stores. Excellent neighborhood makes this property a gem." CA $84 CA $368 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Augusta-Hotels-1-Bedroom.h100386968.Hotel-Information) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/84000000/83660000/83655000/83654982/66cad9b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/84000000/83660000/83655000/83654982/345aff30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83660000/83655000/83654982/1234cea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/84000000/83660000/83655000/83654982/a9f50886.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Adorable 2-br guest suite minutes from SouthPark/Uptown Charlotte 9.4/10 Exceptional (12) "Convenient south Charlotte location on a quiet block in an established neighborhood. Perfect little home away from home for our family of four. Kitchenette is sufficient for preparing small meals. Washer/dryer, shower (no bathtub), and large vanity in the bathroom. Nicely decorated throughout.2nd bedroom is connected to the master by a passage door with an exterior double door opening onto the outside deck. There’s no independent thermostat control in this unit so you have to contact the host,... CA $167 CA $402 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Charlotte-Hotels-Adorable-2-Br-Suite-Minutes-From-SouthParkUptown.h83654982.Hotel-Information) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/84000000/83520000/83512700/83512615/1ef53e6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83520000/83512700/83512615/a887b30c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/84000000/83520000/83512700/83512615/22d09eb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/84000000/83520000/83512700/83512615/bb59e8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW! Designer Remodel w King Bed, Fast WiFi Matthews 9.4/10 Exceptional (20) "The place was beautiful will be returning for family gatherings " CA $251 CA $604 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Charlotte-Hotels-NEW-Designer-Remodel-W-King-Bed.h83512615.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-27&endDate=2025-10-28®ionId=6057938&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Guest-Houses.d6057938-aaGuestHouses.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Guest-Houses.d6057938-aaGuestHouses.Travel-Guide-Accommodation) ## Top South Carolina Midlands Hotel Reviews ![Hampton Inn Columbia-I-26 Airport](//images.trvl-media.com/lodging/1000000/10000/7600/7503/e8ace719_y.jpg) ### Hampton Inn Columbia-I-26 Airport 10/10 Excellent "5 stars " [](https://expedia.ca/Columbia-Hotels-Hampton-Inn-Columbia-I-26-Airport.h7503.Hotel-Information) ![Comfort Inn & Suites](//images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites 10/10 Excellent "Friendly staff, clean rooms, comfortable beds, nice breakfast. Just a very nice hotel experience. Will definitely stay here again. " [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![ La Quinta Inn by Wyndham Columbia NE/Fort Jackson](//images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50_y.jpg) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson 10/10 Excellent "It was solid." [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Tru By Hilton Columbia Downtown](//images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "Excellent accomodations. Room was very clean, hotel staff friendly, good breakfast menu. Overall great experience " [](https://expedia.ca/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](//images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Clean excelentt" [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia at Harbison, SC](//images.trvl-media.com/lodging/4000000/3540000/3531500/3531475/df25b656_y.jpg) ### Country Inn & Suites by Radisson, Columbia at Harbison, SC 10/10 Excellent "Staff was friendly and courteous. I felt at home away from home. Thank you for all you do to make your guests feel welcome!" [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h3531475.Hotel-Information) ![Cambria Hotel Columbia Downtown The Vista](//images.trvl-media.com/lodging/77000000/76600000/76599300/76599223/e2b9c83a_y.jpg) ### Cambria Hotel Columbia Downtown The Vista 10/10 Excellent "Clean, clean, accomodating, bar on site friendly staff, convenient parking eith on/out options. Will definitely stay ahain when zo return to S.C." [](https://expedia.ca/Columbia-Hotels-Cambria-Hotel-Columbia-Downtown-The-Vista.h76599223.Hotel-Information) ![Wyndham Garden Columbia/Ft. Jackson](//images.trvl-media.com/lodging/78000000/77820000/77814700/77814689/e6cbdb45_y.jpg) ### Wyndham Garden Columbia/Ft. Jackson 10/10 Excellent "It’s okay except one car noise " [](https://expedia.ca/Columbia-Hotels-Hotel-Columbia-Inn-Suites.h77814689.Hotel-Information) ![Howard Johnson by Wyndham Florence](//images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Clean room" [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ## Find out more about South Carolina Midlands ## South Carolina Midlands Guest Houses information | Number of reviews | | | --- | --- | | Accommodation | Guest Houses | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Allen University](https://www.expedia.ca/Allen-University-Hotels.0-l6245638-0.Travel-Guide-Filter-Hotels) - [B&B in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Bed-And-Breakfast.d553248634998974994-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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