Title: South Carolina Midlands Guest Houses from CA $210 | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/183000/183997-State-House.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in South Carolina Midlands from CA $210 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-09-26&endDate=2025-09-28&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-03&endDate=2025-10-05&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-17&endDate=2025-10-19&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select South Carolina Midlands Guest Houses ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100190000/100186000/100185994/9f077566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100190000/100186000/100185994/bb8d6d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/101000000/100190000/100186000/100185994/4044fefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100190000/100186000/100185994/b3f5aa6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amazing Studio Guesthouse, in beautiful Columbia Lake community suburb. Lake Carolina 10/10 Exceptional (9) "We were in the area for a family wedding and this was the closest we could get to the venue area (about 15-20min north). It was a nice, quiet, clean spot to relax between the events. The bed was cozy and the kitchen was well-equipped. Our two-year-old loved the big projector screen for some morning Ms Rachel videos! ;) Raul was easy to communicate with and super helpful. Neighborhood is quiet and we enjoyed walks with our kiddo (sadly he didn't get much playtime at the park with everything going... CA $165 CA $215 total includes taxes & fees Sep 21 - Sep 22 [](https://www.expedia.ca/Columbia-Hotels-Amazing-Studio-Guesthouse.h100185994.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111620000/111619300/111619253/d61c103b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, offices](https://images.trvl-media.com/lodging/112000000/111620000/111619300/111619253/7268081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, offices](https://images.trvl-media.com/lodging/112000000/111620000/111619300/111619253/4b9ebd7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111620000/111619300/111619253/9dd4c5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casita - COLA & Hot Tub Downtown Columbia 9.8/10 Exceptional (6) "Nice and quiet spot to relax and unwind." CA $159 CA $272 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Columbia-Hotels-Casita-COLA-Hot-Tub.h111619253.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/101000000/100670000/100666500/100666449/7588d0fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100670000/100666500/100666449/86896549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100670000/100666500/100666449/1e93f019.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/101000000/100670000/100666500/100666449/89cec47c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wren's Nest | 1BR 2BA Guesthouse Earlewood 10/10 Exceptional (2) "We loved the property and will definitely stay again if the opportunity arises." [](https://www.expedia.ca/Columbia-Hotels-The-Wren-1BR-2BA-Guesthouse.h100666449.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/71000000/70070000/70060600/70060537/e459bc7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70070000/70060600/70060537/9ea95753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/71000000/70070000/70060600/70060537/57359d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/71000000/70070000/70060600/70060537/2aabbd2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 818 Queen St · Relaxing Cozy Apartment in Downtown Cola Downtown Columbia 9.6/10 Exceptional (7) "We stayed here for family weekend at UofSC and it was perfect! Great location, safe area and very comfortable. Will definitely stay here again!" [](https://www.expedia.ca/Columbia-Hotels-818-Queen-St-Relaxing-Cozy-Apartment-In-Downtown-Cola.h70060537.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/110000000/109610000/109608400/109608359/2e1bdb4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109610000/109608400/109608359/ad8ae37f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109610000/109608400/109608359/35f50241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/110000000/109610000/109608400/109608359/8964d08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Full Kitchen, Wi-Fi, TV, Washer & Dryer Downtown Columbia 8.0/10 Very good (1) "Very quiet and comfortable! Clean an very cozy! Very relaxing " [](https://www.expedia.ca/Columbia-Hotels-Full-Kitchen.h109608359.Hotel-Information) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/27000000/26610000/26603100/26603084/53422b43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/27000000/26610000/26603100/26603084/74f7ccb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/27000000/26610000/26603100/26603084/be4b7b0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26610000/26603100/26603084/0c253bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Burch's Carriage House Society Hill 9.8/10 Exceptional (30) "This pet friendly accomodation was perfect for my trip to South Carolina! Will definitely be booking this again on my next trip to the area." CA $117 CA $210 total includes taxes & fees Sep 21 - Sep 22 [](https://www.expedia.ca/Society-Hill-Hotels-Burchs-Carriage-House.h26603084.Hotel-Information) ![Smart TV, books](https://images.trvl-media.com/lodging/120000000/119050000/119042200/119042171/e8576b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, stovetop, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/120000000/119050000/119042200/119042171/fcf82201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/120000000/119050000/119042200/119042171/fa16f082.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/120000000/119050000/119042200/119042171/cfec452e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### BlueHeronLake-Guesthouse Studio Columbia [](https://www.expedia.ca/Columbia-Hotels-BlueHeronLake-Guesthouse-Studio.h119042171.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-03&endDate=2025-10-04®ionId=6057938&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Guest-Houses.d6057938-aaGuestHouses.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Guest-Houses.d6057938-aaGuestHouses.Travel-Guide-Accommodation) ## Top South Carolina Midlands Hotel Reviews ![Marriott Columbia](//images.trvl-media.com/lodging/1000000/20000/17400/17353/4bcf0c43_y.jpg) ### Marriott Columbia 10/10 Excellent "Convenient located downtown with very nice rooms." [](https://expedia.ca/Columbia-Hotels-Marriott-Columbia.h17353.Hotel-Information) ![ La Quinta Inn by Wyndham Columbia NE/Fort Jackson](//images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50_y.jpg) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson 10/10 Excellent "Very clean and great breakfast " [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Howard Johnson by Wyndham Florence](//images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "The front desk staff were very kind and attentive. The room was spacious and clean! " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Tru By Hilton Columbia Downtown](//images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "The hotel is immaculate! Everything is so clean and new. The breakfast in the morning was delicious!!! Definitely NOT your typical free breakfast! Had many hot items including a breakfast taco bar that amazing!" [](https://expedia.ca/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information) ![Wyndham Garden Columbia/Ft. Jackson](//images.trvl-media.com/lodging/78000000/77820000/77814700/77814689/e6cbdb45_y.jpg) ### Wyndham Garden Columbia/Ft. Jackson 10/10 Excellent "The hotel was clean and very quiet. Easy to get to off the exit. Would definitely stay again " [](https://expedia.ca/Columbia-Hotels-Hotel-Columbia-Inn-Suites.h77814689.Hotel-Information) ![Park Inn by Radisson Florence, SC](//images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "Arrived to stay over night for work, walked in to a very clean modern hotel. Receptionist were very friendly, informative and helpful. Rooms were very clean, and the bed slept amazing. Spacious room, and bathroom. Delicious breakfast! We will be staying here as often as we can when we have to stay over for work. " [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Motel 6 West Columbia, SC - Airport](//images.trvl-media.com/lodging/2000000/1130000/1123200/1123132/d424a6cf_y.jpg) ### Motel 6 West Columbia, SC - Airport 10/10 Excellent "Clean friendly" [](https://expedia.ca/West-Columbia-Hotels-Motel-6-West-Columbia.h1123132.Hotel-Information) ![Graduate by Hilton Columbia SC](//images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "Great place! Really neat decor and feel! Highly recommend for those wanting to be close to campus! " [](https://expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](//images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "Great place to stay while in Columbia!" [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ## Find out more about South Carolina Midlands ## South Carolina Midlands Guest Houses information | Number of reviews | 53 | | --- | --- | | Accommodation | 7 Guest Houses | | Lowest Price | CA $210 | | Highest Price | CA $272 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Allen University](https://www.expedia.ca/Allen-University-Hotels.0-l6245638-0.Travel-Guide-Filter-Hotels) - [B&B in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Bed-And-Breakfast.d553248634998974994-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Guest-Houses.d553248634998974994-aaGuestHouses.Travel-Guide-Accommodation) - [Arcadia Lakes Hotels](https://www.expedia.ca/Arcadia-Lakes-Hotels.d553248634998974994.Travel-Guide-Hotels) - [Inns in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Inns.d553248634998974994-aaInns.Travel-Guide-Accommodation) - 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