Title: Book the Best BUSINESS Hotels in South Carolina Lowcountry in 2026 | Expedia.ca [South Carolina Lowcountry Travel Guide](https://expedia.ca/South-Carolina-Lowcountry.dx553248635975748945)[Hotels in South Carolina Lowcountry](https://expedia.ca/South-Carolina-Lowcountry-Hotels.d553248635975748945.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Lowcountry](https://expedia.ca/South-Carolina-Lowcountry-Vacation-Rentals.d553248635975748945.Travel-Guide-VacationRentals)[Flights to South Carolina Lowcountry](https://expedia.ca/Cheap-Flights-To-South-Carolina-Lowcountry.d553248635975748945.Travel-Guide-Flights)[Things to do in South Carolina Lowcountry](https://expedia.ca/Things-To-Do-In-South-Carolina-Lowcountry.d553248635975748945.Travel-Guide-Activities)[South Carolina Lowcountry Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Lowcountry.d553248635975748945.Car-Rental-Guide)[South Carolina Lowcountry Vacation Packages](https://expedia.ca/South-Carolina-Lowcountry.d553248635975748945.Destination-Travel-Guides) ![We saw a sign for some church ruins. How could I not go? These ruins are owned by a private owner and can be walked around free of charge. Known also as the Sheldon Church or Old Sheldon Church, the building was originally known as Prince William's Parish Church. The church was built as a chapel of ease in the English Georgian style, using the Roman Tuscan or Doric order, between 1745 and 1753. The traditional understanding is that Prince William's was burned by the British in 1779 during the Revolutionary War, rebuilt in 1826, and then burned again in 1865 during the Civil War:](https://images.trvl-media.com/place/12111/0b8d55d2-2a0a-45fe-a9a1-0f2d7b12db09.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michael Schuier # Find Business Hotels in South Carolina Lowcountry, SC - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Lowcountry Business Hotels Tonight [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=553248635975748945&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 20 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635975748945&startDate=2025-12-20&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635975748945&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635975748945&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for South Carolina Lowcountry business-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/975ff0d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/714de801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/2ac82115.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Electric vehicle charging station](https://images.trvl-media.com/lodging/1000000/30000/24300/24264/20a9a8fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Point South [](https://www.expedia.ca/Beaufort-Hotels-Best-Western-Point-South.h24264.Hotel-Information) Yemassee 8.0/10 Very good (1001) "the room was very clean. nice quiet place to sleep. the grounds were well maintained. great bargain for the price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonia CA $110 CA $125 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Beaufort-Hotels-Best-Western-Point-South.h24264.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/1000000/20000/14500/14431/e30ea668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14500/14431/w3837h2557x3y3-450c152e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; southern cuisine, alfresco dining ](https://images.trvl-media.com/lodging/1000000/20000/14500/14431/w3837h2557x3y3-fb1107cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14500/14431/w3837h2560x3y0-9d5ef433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Savannah [](https://www.expedia.ca/Savannah-Hotels-Hyatt-Regency-Savannah.h14431.Hotel-Information) Historic Downtown Savannah 9.0/10 Wonderful (3536) "Great hotel with great access to the river walk." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $146 CA $216 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Savannah-Hotels-Hyatt-Regency-Savannah.h14431.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1370000/1367200/1367198/w3840h2556x0y4-01951b4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1370000/1367200/1367198/w3837h2557x3y3-ca77fba1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/2000000/1370000/1367200/1367198/f4a4fe6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Non Smoking (Bathtub)](https://images.trvl-media.com/lodging/2000000/1370000/1367200/1367198/w3837h2556x3y4-35e45fdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Richmond Hill Inn [](https://www.expedia.ca/Savannah-Hotels-Best-Western-Plus-Richmond-Hill-Inn.h1367198.Hotel-Information) Richmond Hill 8.8/10 Excellent (1502) "Clean, comfortable room with a nice staff and breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank CA $109 CA $132 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Savannah-Hotels-Best-Western-Plus-Richmond-Hill-Inn.h1367198.Hotel-Information) ![Arcade](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/ee35661b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach bar](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/672e8e1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/5dfa0010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to midnight, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/f7f42667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beach House Resort Hilton Head [](https://www.expedia.ca/Hilton-Head-Island-Hotels-Beach-House-Hilton-Head.h20657.Hotel-Information) South End 8.8/10 Excellent (1003) "Clean room , friendly staff, great beach access " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theodore CA $149 CA $221 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Hilton-Head-Island-Hotels-Beach-House-Hilton-Head.h20657.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2310000/2301400/2301351/53753aae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2310000/2301400/2301351/w5568h3709x0y3-363bb482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2310000/2301400/2301351/40bb4025.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2310000/2301400/2301351/524d1aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Charleston Airport/Convention Center [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-Charleston-AirportConvention-Center.h2301351.Hotel-Information) North Charleston 9.4/10 Exceptional (1149) "Clean room, nice staff, amenities were all great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keisha CA $125 CA $150 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Charleston-Hotels-Hyatt-Place-Charleston-AirportConvention-Center.h2301351.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1550000/1540100/1540089/0a108d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1550000/1540100/1540089/068e9b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1550000/1540100/1540089/6d8127d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1550000/1540100/1540089/bf808749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Walterboro [](https://www.expedia.ca/Walterboro-Hotels-Microtel-Inn-Suites-By-Wyndham-Walterboro.h1540089.Hotel-Information) Walterboro 8.0/10 Very good (1000) "Clean, great staff, no eggs or meat at breakfast, small bathroom vanity " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura CA $130 CA $146 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/Walterboro-Hotels-Microtel-Inn-Suites-By-Wyndham-Walterboro.h1540089.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/2876f083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/736730eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/ed4e0dc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/5b388daa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Walterboro I-95 [](https://www.expedia.ca/Walterboro-Hotels-Comfort-Inn-Suites-Walterboro-I-95.h900144.Hotel-Information) Walterboro 8.6/10 Excellent (1000) "Room is clean and staff was very courteous and check in was a breeze. Would stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teddy CA $147 CA $164 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Walterboro-Hotels-Comfort-Inn-Suites-Walterboro-I-95.h900144.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284680/b827ff63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284680/2382de78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284680/b9d099b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284680/76d3abf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Beaufort, SC [](https://www.expedia.ca/Beaufort-Hotels-Tru-By-Hilton-Beaufort.h49284680.Hotel-Information) Beaufort 9.0/10 Wonderful (709) "Awesome stay!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $134 CA $148 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Beaufort-Hotels-Tru-By-Hilton-Beaufort.h49284680.Hotel-Information) ![Suite, 1 King Bed, Non Smoking, Courtyard View](https://images.trvl-media.com/lodging/1000000/20000/16200/16132/f0afd3ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/16200/16132/099c0418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16200/16132/1711686c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible, Bathtub (Pet Friendly)](https://images.trvl-media.com/lodging/1000000/20000/16200/16132/88f97bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Of Walterboro [](https://www.expedia.ca/Walterboro-Hotels-Best-Western-Of-Walterboro.h16132.Hotel-Information) Walterboro 7.6/10 Good (338) "Room was very clean and quiet. Easy check in and check out. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $108 CA $121 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Walterboro-Hotels-Best-Western-Of-Walterboro.h16132.Hotel-Information) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/e398b7e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/484680bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/b222d074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 2 outdoor pools, open 7:00 AM to 9:30 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/f14a74b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Beachfront Resort & Spa Hilton Head Island [](https://www.expedia.ca/Hilton-Head-Hotels-Marriott-Hilton-Head-Resort-Spa.h583363.Hotel-Information) Mid Island 8.4/10 Very good (1396) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ngone Lon CA $191 CA $263 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Hilton-Head-Hotels-Marriott-Hilton-Head-Resort-Spa.h583363.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=553248635975748945&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top South Carolina Lowcountry Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [Condo Resorts in Ashdale ](https://www.expedia.ca/Ashdale-Condominium-Resort.d553248635975873633-aaCondominiumResort.Travel-Guide-Accommodation) - [Guest Houses in Burton ](https://www.expedia.ca/Burton-Guest-Houses.d553248634999352221-aaGuestHouses.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Burton ](https://www.expedia.ca/Burton-Hotels-Beach-Hotel.0-0-d553248634999352221-tBeachHotel.Travel-Guide-Filter-Hotels) - [Burton Hotels ](https://www.expedia.ca/Burton-Hotels.d553248634999352221.Travel-Guide-Hotels) - [Inns in Burton ](https://www.expedia.ca/Burton-Inns.d553248634999352221-aaInns.Travel-Guide-Accommodation) - [Vacation Homes in Burton ](https://www.expedia.ca/Burton-Private-Vacation-Homes.d553248634999352221-aaPrivateVacationHomes.Travel-Guide-Accommodation) - 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