Title: Book the Best BUSINESS Hotels in South Carolina Lowcountry in 2026 | Expedia.ca [South Carolina Lowcountry Travel Guide](https://expedia.ca/South-Carolina-Lowcountry.dx553248635975748945)[Hotels in South Carolina Lowcountry](https://expedia.ca/South-Carolina-Lowcountry-Hotels.d553248635975748945.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Lowcountry](https://expedia.ca/South-Carolina-Lowcountry-Vacation-Rentals.d553248635975748945.Travel-Guide-VacationRentals)[Flights to South Carolina Lowcountry](https://expedia.ca/Cheap-Flights-To-South-Carolina-Lowcountry.d553248635975748945.Travel-Guide-Flights)[Things to do in South Carolina Lowcountry](https://expedia.ca/Things-To-Do-In-South-Carolina-Lowcountry.d553248635975748945.Travel-Guide-Activities)[South Carolina Lowcountry Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Lowcountry.d553248635975748945.Car-Rental-Guide)[South Carolina Lowcountry Vacation Packages](https://expedia.ca/South-Carolina-Lowcountry.d553248635975748945.Destination-Travel-Guides) ![We saw a sign for some church ruins. How could I not go? These ruins are owned by a private owner and can be walked around free of charge. Known also as the Sheldon Church or Old Sheldon Church, the building was originally known as Prince William's Parish Church. The church was built as a chapel of ease in the English Georgian style, using the Roman Tuscan or Doric order, between 1745 and 1753. The traditional understanding is that Prince William's was burned by the British in 1779 during the Revolutionary War, rebuilt in 1826, and then burned again in 1865 during the Civil War:](https://images.trvl-media.com/place/12111/0b8d55d2-2a0a-45fe-a9a1-0f2d7b12db09.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michael Schuier ![](https://images.trvl-media.com/place/12111/0b8d55d2-2a0a-45fe-a9a1-0f2d7b12db09.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Lowcountry Business Hotels Tonight [Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=553248635975748945&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Feb 7 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975748945&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975748945&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635975748945&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for South Carolina Lowcountry business-friendly hotels ![Arcade](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/ee35661b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to midnight, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/f7f42667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach bar](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/672e8e1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/5dfa0010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beach House Resort Hilton Head [](https://www.expedia.ca/Hilton-Head-Island-Hotels-Beach-House-Hilton-Head.h20657.Hotel-Information) South End 8.8/10 Excellent (1,049 reviews) "Great outdoor seating on the beach with 24hrs fire pit and heated pool" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Utkal CA $154 CA $226 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Hilton-Head-Island-Hotels-Beach-House-Hilton-Head.h20657.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/w3840h2872x0y4-3cb0e9e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/a1982b07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/aa89c6b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/w3837h2561x3y0-d0889314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta Resort Hilton Head Island [](https://www.expedia.ca/Hilton-Head-Hotels-Sonesta-Resort-Hilton-Head-Island.h2618.Hotel-Information) South End 8.6/10 Excellent (1,230 reviews) "Staffs were amazing Great scenery " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nkem CA $152 CA $232 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Hilton-Head-Hotels-Sonesta-Resort-Hilton-Head-Island.h2618.Hotel-Information) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/e398b7e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 2 outdoor pools, open 7:00 AM to 9:30 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/f14a74b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/bc22677e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/590000/583400/583363/484680bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Beachfront Resort & Spa Hilton Head Island [](https://www.expedia.ca/Hilton-Head-Hotels-Marriott-Hilton-Head-Resort-Spa.h583363.Hotel-Information) Mid Island 8.4/10 Very good (1,415 reviews) "Our room was very comfortable and clean. We had an ocean view room and it was amazing looking out at the sunrise and sunset. The desk staff were very warm and friendly and knowledgeable. The valet staff was excellent, especially Joey and Charles. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jill CA $189 CA $261 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Hilton-Head-Hotels-Marriott-Hilton-Head-Resort-Spa.h583363.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/2876f083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/736730eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/5b388daa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/ed4e0dc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Walterboro I-95 [](https://www.expedia.ca/Walterboro-Hotels-Comfort-Inn-Suites-Walterboro-I-95.h900144.Hotel-Information) Walterboro 8.6/10 Excellent (1,018 reviews) "Staff is friendly, breakfast was good and rooms were clean and bed so comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Treama CA $134 CA $150 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Walterboro-Hotels-Comfort-Inn-Suites-Walterboro-I-95.h900144.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1550000/1540100/1540089/0a108d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1550000/1540100/1540089/bf808749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1550000/1540100/1540089/068e9b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/2000000/1550000/1540100/1540089/43bf1081.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Walterboro [](https://www.expedia.ca/Walterboro-Hotels-Microtel-Inn-Suites-By-Wyndham-Walterboro.h1540089.Hotel-Information) Walterboro 8.0/10 Very good (1,001 reviews) "Clean room, friendly staff, pet friendly rooms all with a great price! We loved our visit and highly recommend Microtel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $129 CA $144 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Walterboro-Hotels-Microtel-Inn-Suites-By-Wyndham-Walterboro.h1540089.Hotel-Information) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/4f0133cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, 2 poolside bars](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/aced1e4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/4e548057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/c13a70d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Hilton Head Oceanfront Resort [](https://www.expedia.ca/Hilton-Head-Hotels-Omni-Hilton-Head-Oceanfront-Resort.h14690.Hotel-Information) Mid Island 9.0/10 Wonderful (1,000 reviews) "Beautiful room, attentive staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeromy CA $260 CA $351 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Hilton-Head-Hotels-Omni-Hilton-Head-Oceanfront-Resort.h14690.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/e21613a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/f0591267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/fa89684b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Pool View (Walk-In Shower)](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/e3a23a65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hilton Head Island by IHG [](https://www.expedia.ca/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) South End 8.4/10 Very good (402 reviews) "Clean rooms, great location, nice breakfast. It was a nice 1 night stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Agnes CA $127 CA $140 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567230/928e817c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567230/w3837h2557x3y3-79a0a021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567230/4ee8d90d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567230/w3837h2556x3y3-7455dbb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Walterboro [](https://www.expedia.ca/Walterboro-Hotels-Hampton-Inn-Suites-Walterboro.h18567230.Hotel-Information) Walterboro 9.2/10 Wonderful (1,000 reviews) "The hotel look very nice, the staff was very pleasant and the breakfast was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lawrence CA $213 CA $238 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Walterboro-Hotels-Hampton-Inn-Suites-Walterboro.h18567230.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1260000/1256400/1256324/e3f53c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/2000000/1260000/1256400/1256324/2b7ec7a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1260000/1256400/1256324/cb6dafc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/2000000/1260000/1256400/1256324/73edb984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Hardeeville [](https://www.expedia.ca/Hilton-Head-Hotels-Red-Roof-Inn-Hardeeville.h1256324.Hotel-Information) Hardeeville 8.0/10 Very good (1,464 reviews) "Nice place and staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marisa CA $73 CA $83 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Hilton-Head-Hotels-Red-Roof-Inn-Hardeeville.h1256324.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/16300/16225/a9fdb04b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/20000/16300/16225/59a34862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16300/16225/0a636c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16225/15b290ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Sea Island Inn [](https://www.expedia.ca/Beaufort-Hotels-Best-Western-Sea-Island-Inn.h16225.Hotel-Information) Downtown Beaufort 9.6/10 Exceptional (1,001 reviews) "CLEAN ROOM,GREAT BREAKFAST,NICE STAFF" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynda CA $203 CA $224 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Beaufort-Hotels-Best-Western-Sea-Island-Inn.h16225.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21®ionId=553248635975748945&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top South Carolina Lowcountry Hotel Reviews ![Palmera Inn and Suites](https://images.trvl-media.com/lodging/1000000/570000/564600/564590/28eae64d_y.jpg) ### Palmera Inn and Suites 10/10 Excellent "Pues eso es Great I’m Cleaning" [](https://expedia.ca/Hilton-Head-Hotels-Palmera-Inn-And-Suites.h564590.Hotel-Information) ![Hampton Inn Hilton Head](https://images.trvl-media.com/lodging/1000000/20000/16300/16242/b513d9a5_y.jpg) ### Hampton Inn Hilton Head 10/10 Excellent "The staff was very courteous and helpful. The room was clean." [](https://expedia.ca/Hilton-Head-Hotels-Hampton-Inn-Hilton-Head.h16242.Hotel-Information) ![Comfort Inn & Suites Walterboro I-95](https://images.trvl-media.com/lodging/1000000/910000/900200/900144/12059b6c_y.jpg) ### Comfort Inn & Suites Walterboro I-95 10/10 Excellent "The room was very spacious, clean and beds very comfortable, The staff was especially helpful and friendly. Just a great bargain for the price. Very highly recommended. " [](https://expedia.ca/Walterboro-Hotels-Comfort-Inn-Suites-Walterboro-I-95.h900144.Hotel-Information) ![Holiday Inn Express Hilton Head Island by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/e21613a3_y.jpg) ### Holiday Inn Express Hilton Head Island by IHG 10/10 Excellent "Nice staff. Clean. Great breakfast " [](https://expedia.ca/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) ![Omni Hilton Head Oceanfront Resort](https://images.trvl-media.com/lodging/1000000/20000/14700/14690/c13a70d7_y.jpg) ### Omni Hilton Head Oceanfront Resort 10/10 Excellent "Room was clean quiet and large. The staff was very courteous. Would stay again. " [](https://expedia.ca/Hilton-Head-Hotels-Omni-Hilton-Head-Oceanfront-Resort.h14690.Hotel-Information) ![Sonesta Resort Hilton Head Island](https://images.trvl-media.com/lodging/1000000/10000/2700/2618/220ad345_y.jpg) ### Sonesta Resort Hilton Head Island 10/10 Excellent "Everything about my stay was great...very clean, upscale rooms, friendly and helpful staff. I really enjoyed it." [](https://expedia.ca/Hilton-Head-Hotels-Sonesta-Resort-Hilton-Head-Island.h2618.Hotel-Information) ![Beach House Resort Hilton Head](https://images.trvl-media.com/lodging/1000000/30000/20700/20657/b454fbd2_y.jpg) ### Beach House Resort Hilton Head 10/10 Excellent "This beautiful, relaxing and well appointed one bedroom apartment in Bimini was the perfect stay for my week of diving and exploring here. Upon arrival, it was spotless and welcoming, with what appears to be all new fixtures, appliances, bedding, towels, ample kitchen supplies and furniture. The AC works well but with my January visit, I found it unnecessary to run. The ceiling fan in the bedroom was sufficient and a bonus. They exterior is well maintained and there is a gorgeous lounging area on the waterfront deck. Traveling as a single woman, I felt very safe and secure with the multiple security cameras posted around the complex. There is also a very friendly and helpful property manager on site. My only inquiry all week regarding using the TV was answered immediately, and addressed through the complement of staff and techs that the owner of the property has on hand. I had friends staying nearby at the Resort World hotel, and problems were frequent and late in rectifying - no water pressure, couldn't enter their room and waited up to an hour, at night, for it to be fixed - and this happened twice! For travelers like myself, on a budget but seeking quality accommodations, I hit the jackpot with Bimini Bay View Apartments. Finally, the owner is very responsive, replies immediately, and cares about the guests. I can't recommend this place more highly. Five shiny stars! " [](https://expedia.ca/Hilton-Head-Island-Hotels-Beach-House-Hilton-Head.h20657.Hotel-Information) ![The Westin Hilton Head Island Resort & Spa](https://images.trvl-media.com/lodging/1000000/30000/22200/22170/2c505874_y.jpg) ### The Westin Hilton Head Island Resort & Spa 10/10 Excellent "clean. nice layout" [](https://expedia.ca/Hilton-Head-Hotels-The-Westin-Hilton-Head-Island-Resort-Spa.h22170.Hotel-Information) ![Red Roof Inn Hardeeville](https://images.trvl-media.com/lodging/2000000/1260000/1256400/1256324/cb6dafc3_y.jpg) ### Red Roof Inn Hardeeville 10/10 Excellent "Spacious room, excellent comfortable bed. Nice staff and easy check in" [](https://expedia.ca/Hilton-Head-Hotels-Red-Roof-Inn-Hardeeville.h1256324.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [Condo Resorts in Ashdale ](https://www.expedia.ca/Ashdale-Condominium-Resort.d553248635975873633-aaCondominiumResort.Travel-Guide-Accommodation) - [Guest Houses in Burton ](https://www.expedia.ca/Burton-Guest-Houses.d553248634999352221-aaGuestHouses.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Burton ](https://www.expedia.ca/Burton-Hotels-Beach-Hotel.0-0-d553248634999352221-tBeachHotel.Travel-Guide-Filter-Hotels) - [Burton Hotels ](https://www.expedia.ca/Burton-Hotels.d553248634999352221.Travel-Guide-Hotels) - [Inns in Burton ](https://www.expedia.ca/Burton-Inns.d553248634999352221-aaInns.Travel-Guide-Accommodation) - [Vacation Homes in Burton ](https://www.expedia.ca/Burton-Private-Vacation-Homes.d553248634999352221-aaPrivateVacationHomes.Travel-Guide-Accommodation) - 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