Title: Book the Best SHOPPING Hotels in Sikeston in 2026 | Expedia.ca [Hotels in Sikeston](https://expedia.ca/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Vacation Rentals in Sikeston](https://expedia.ca/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)[Flights to Sikeston](https://expedia.ca/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Sikeston Car Rentals](https://expedia.ca/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.ca/Sikeston.d6058766.Destination-Travel-Guides) ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sikeston Shopping Hotels Tonight [Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 7 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6058766&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Sikeston hotels with shopping nearby ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/42667f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston I-55 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1,003 reviews) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $117 CA $133 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/f432dafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/6d0c8b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/564d6e43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) Cape Girardeau 10/10 Exceptional (150 reviews) "Such a great place and location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy H. CA $205 CA $333 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/e8e18ca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/4b9b083c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/de8fdc64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, stereo](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/73866b5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dexter Homestead. Very Cozy & NEW Remodel ! [](https://www.expedia.ca/Dexter-Hotels-Dexter-Homestead-Very-Cozy-NEW-Remodel.h63162828.Hotel-Information) Dexter 7.8/10 Good (30 reviews) "A weekin Dexter at this old, charming house. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan R. CA $122 CA $267 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Dexter-Hotels-Dexter-Homestead-Very-Cozy-NEW-Remodel.h63162828.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/89000000/88870000/88869200/88869111/3d5ec048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88870000/88869200/88869111/60d7d429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/89000000/88870000/88869200/88869111/48434221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88870000/88869200/88869111/853dbdda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail! [](https://www.expedia.ca/Makanda-Hotels-3-Minutes-To-Giant-City-6-Minutes-To-SIU-4-Minutes-To-Shawnee-Winetrail.h88869111.Hotel-Information) Makanda 9.8/10 Exceptional (60 reviews) "Stephen very friendly and accomadations excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Walter H. CA $129 CA $247 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Makanda-Hotels-3-Minutes-To-Giant-City-6-Minutes-To-SIU-4-Minutes-To-Shawnee-Winetrail.h88869111.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/d22aee4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/12dcf221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/2c1a0ed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31190000/31190000/31189922/b0f0a7b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rest, Relax and Renew. Our log cabin experience awaits your arrival. [](https://www.expedia.ca/Anna-Hotels-Rest.h31189922.Hotel-Information) Anna 10/10 Exceptional (405 reviews) "Nice cabin and beautiful scenery! We enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hannah G. CA $160 CA $274 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Anna-Hotels-Rest.h31189922.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/124000000/123430000/123422100/123422053/1d4ebdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/124000000/123430000/123422100/123422053/d46d2628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123430000/123422100/123422053/8bdb44ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123430000/123422100/123422053/249a50ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy and Updated Farmhouse with King Suite [](https://www.expedia.ca/Anna-Hotels-Cozy-And-Updated-Farmhouse-With-King-Suite.h123422053.Hotel-Information) Anna 10/10 Exceptional (1 review) "Older farmhouse but comfy and had everything we needed for our stay. I would recommend without hesitation " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marla K. CA $108 CA $202 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Anna-Hotels-Cozy-And-Updated-Farmhouse-With-King-Suite.h123422053.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27150000/27145300/27145221/05ba3853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/28000000/27150000/27145300/27145221/05da8d7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/28000000/27150000/27145300/27145221/d3b8d0f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/28000000/27150000/27145300/27145221/1a34a819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Contemporary Glamping with Native American Appeal [](https://www.expedia.ca/Anna-Hotels-Contemporary-Glamping-With-Native-American-Appeal.h27145221.Hotel-Information) Anna 9.8/10 Exceptional (157 reviews) "Every Th I was perfect close to the shopping we wanted to and such quiet area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina S. CA $245 CA $453 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Anna-Hotels-Contemporary-Glamping-With-Native-American-Appeal.h27145221.Hotel-Information) ![Smart TV, fireplace, table tennis](https://images.trvl-media.com/lodging/90000000/89790000/89781400/89781354/9fd80641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89790000/89781400/89781354/83753556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/90000000/89790000/89781400/89781354/2352e152.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89790000/89781400/89781354/f5019574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury 4BR Log Cabin Near SIU & Wine Trail [](https://www.expedia.ca/Makanda-Hotels-Luxury-Log-Cabin-Near-SIU.h89781354.Hotel-Information) Makanda 10/10 Exceptional (42 reviews) "The cabin was beautiful and just as described. Location was relaxing and really enjoyed the firepit. Will definitely consider staying again when in the area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marjorie H. CA $587 CA $735 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Makanda-Hotels-Luxury-Log-Cabin-Near-SIU.h89781354.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/809a6239.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/c405b8b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/2fc99c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/118000000/117040000/117036800/117036792/bcefe410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Farm Cottage on 800-Acre Orchard [](https://www.expedia.ca/Alto-Pass-Hotels-Farm-Immersion-Experience-At-Rendleman-Orchards.h117036792.Hotel-Information) Alto Pass 9.8/10 Exceptional (8 reviews) "What an amazing spot! Perfect weekend getaway, close to several hikes in Shawnee and we enjoyed our time on the Rendleman Orchard. Came on a girls trip, but we agreed it would be a great spot for a weekend with our partners and kids. Will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julia S. CA $267 CA $333 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Alto-Pass-Hotels-Farm-Immersion-Experience-At-Rendleman-Orchards.h117036792.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/de7e2348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/d1a4afba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/eab48480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/0c3489d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided [](https://www.expedia.ca/Secluded-In-The-Woods.h89701234.Hotel-Information) Greenville 10/10 Exceptional (6 reviews) "Cute, cozy, private getaway that you won't want to leave!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jade G. CA $209 CA $349 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Secluded-In-The-Woods.h89701234.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21®ionId=6058766&adults=2&location_highlights_explore=shopping&sort=RECOMMENDED&openPlayBack=true) ## Top Sikeston Hotel Reviews ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "The woman who checked us in. She was so helpful!!" [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean room and shower, ruffled hotel toilet paper, dinner buffet, breakfast buffet, hot tub and pool. And pets are welcome. Great service and great value. " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Great breakfast. Clean room Quiet" [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ." [](https://expedia.ca/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "The room was lage and clean. We really enjoyed the free food and drinks provided." [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Clean room,friendly staff,free popcorn and soda for the kids.Very nice,attractive rooms." [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Super 8 by Wyndham Sikeston/Miner Area](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe_y.jpg) ### Super 8 by Wyndham Sikeston/Miner Area 10/10 Excellent "Great Experience " [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg) ### Candlewood Suites Cape Girardeau by IHG 10/10 Excellent "Staff was friendly. Check-in was easy. The room was spotless. " [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Everything was excellent" [](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Cars - [B&B in Advance ](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Advance ](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - [Advance Hotels ](https://www.expedia.ca/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) - [Lodges in Advance ](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - [Motels in Advance ](https://www.expedia.ca/Advance-Motels.d553248634983475122-aaMotels.Travel-Guide-Accommodation) - 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