Title: The 10 Best Hotels Near Sierra Vista Regional Medical Center, San Luis Obispo from CA $99 | Expedia.ca

  

[Foothill Travel Guide](https://expedia.ca/San-Luis-Obispo-Foothill.dx896141079926198272)[Sierra Vista Regional Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Sierra-Vista-Regional-Medical-Center.d553248621560543927.Car-Rental-Guide)[Sierra Vista Regional Medical Center Vacations](https://expedia.ca/Sierra-Vista-Regional-Medical-Center-Foothill.d553248621560543927.Vacation-Attraction)

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# Find hotels near Sierra Vista Regional Medical Center, San Luis Obispo from CA $99

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## Check prices for these dates

Tonight

[Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=553248621560543927&startDate=2025-10-12&endDate=2025-10-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=553248621560543927&startDate=2025-10-13&endDate=2025-10-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248621560543927&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248621560543927&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Top Hotels Close to Sierra Vista Regional Medical Center

![Junior Suite, City View | Terrace/patio](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/881d3938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/2123b0db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/cb924494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/41e3049f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Petit Soleil

1.3 km from Sierra Vista Regional Medical Center

9.8/10

Exceptional

(247)

"Our stay was wonderful, highly recommend!"

CA $213

CA $242 total

includes taxes & fees

Oct 29 - Oct 30

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Petit-Soleil.h102995602.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/65dca818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/6eb0f757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/b42da2cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Suites Downtown San Luis Obispo

1.3 km from Sierra Vista Regional Medical Center

9.4/10

Exceptional

(1240)

"Very nice stay. "

CA $177

CA $230 total

includes taxes & fees

Nov 10 - Nov 11

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/f3abfe0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/88590a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Paseo King Room](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/0c2ec67b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Morro Suite | Living area](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel San Luis Obispo

Downtown San Luis Obispo, 1.3 km from Sierra Vista Regional Medical Center

9.6/10

Exceptional

(530)

"Great location. "

CA $458

CA $520 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information)

![Egyptian cotton sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/2000000/1060000/1054700/1054670/45b50682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1054700/1054670/2fcd8b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/2000000/1060000/1054700/1054670/bb34347e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/2000000/1060000/1054700/1054670/5f3b3687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Luis Creek Lodge

1.4 km from Sierra Vista Regional Medical Center

9.4/10

Exceptional

(1000)

"Nice rooms, good staff and tasty breakfast "

CA $181

CA $231 total

includes taxes & fees

Nov 3 - Nov 4

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-San-Luis-Creek-Lodge.h1054670.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/99fa5dc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/b8f67749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/51fe5539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/d050f4c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

1.4 km from Sierra Vista Regional Medical Center

9.0/10

Wonderful

(1752)

"Great place to stay in San Luis Obispo, close to downtown"

CA $187

CA $213 total

includes taxes & fees

Nov 10 - Nov 11

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/462ce0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/cd19526e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/880cde75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apple Farm

1.5 km from Sierra Vista Regional Medical Center

9.0/10

Wonderful

(1505)

"Great place will stay again! "

CA $150

CA $210 total

includes taxes & fees

Oct 13 - Oct 14

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/03ecb72d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/a7600fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/3327b2cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/b2c7c1b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Wayfarer San Luis Obispo, Tapestry Collection by Hilton

1.3 km from Sierra Vista Regional Medical Center

9.0/10

Wonderful

(1004)

"Great place to stay when visiting my son. "

CA $165

CA $195 total

includes taxes & fees

Nov 10 - Nov 11

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Wayfarer-San-Luis-Obispo.h19984.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/f5b74a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/a36ab0c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/ab6971ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hiking](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/821d7298.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Cuesta Inn, BW Signature Collection

1.4 km from Sierra Vista Regional Medical Center

8.8/10

Excellent

(1065)

"Our stay was wonderful!"

CA $163

CA $185 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/780d8f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cozy Queen, Accessible](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/e23aec53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/c28bd6d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/e72b7525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Granada Hotel & Bistro

Downtown San Luis Obispo, 1.5 km from Sierra Vista Regional Medical Center

9.2/10

Wonderful

(786)

"Super cute boutique hotel with cozy rooms and a cute bar and restaurant downstairs. Upstairs has a pretty patio with coffee in the morning. "

CA $311

CA $354 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Granada-Hotel-Bistro.h5531224.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/2000000/1160000/1151800/1151757/e5e41848.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast area](https://images.trvl-media.com/lodging/2000000/1160000/1151800/1151757/fa728569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/2000000/1160000/1151800/1151757/fcd86481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1160000/1151800/1151757/4b6152bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Peach Tree Inn

1.4 km from Sierra Vista Regional Medical Center

8.8/10

Excellent

(1001)

"Very cordial staff, great rooms and location."

CA $139

CA $167 total

includes taxes & fees

Oct 13 - Oct 14

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Peach-Tree-Inn.h1151757.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/0fb1832a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/bd13f21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily cooked-to-order breakfast](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/f7ad1a0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, 1 Queen Bed](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/35aa9a41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Garden Street Inn, A Kirkwood Collection Hotel

Downtown San Luis Obispo, 1.7 km from Sierra Vista Regional Medical Center

9.2/10

Wonderful

(703)

"My stay at this hotel was wonderful. The staff was always friendly and helpful, the facilities were clean and well-maintained, and the location was perfect. The room was comfortable and had everything I needed. I would definitely recommend it and stay again."

CA $301

CA $342 total

includes taxes & fees

Oct 13 - Oct 14

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Garden-Street-Inn.h25838284.Hotel-Information)

![Sundeck](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/18ffa136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/41f2d375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/42ac20df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/786b3840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HOTEL CERRO, Autograph Collection

Downtown San Luis Obispo, 1.6 km from Sierra Vista Regional Medical Center

9.2/10

Wonderful

(460)

"We had a great stay"

CA $283

CA $369 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information)

![Breakfast area](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367217/68109ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367217/b9bf9c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367217/deafdb97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367217/f95ba810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Luis Inn And Suites

Foothill, 0.7 km from Sierra Vista Regional Medical Center

7.0/10

Good

(314)

"Room was reasonable, clean and staff was helpful."

CA $62

CA $110 total

includes taxes & fees

Nov 4 - Nov 5

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-San-Luis-Inn-And-Suites.h1367217.Hotel-Information)

![Standard Room, 1 Queen Bed](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520604/0ebb120a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520604/88ef4719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520604/b76c2fa4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds | Bathroom](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520604/9f863d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sunbeam Motel

1.3 km from Sierra Vista Regional Medical Center

8.2/10

Very good

(745)

"Great location, small number of units allows for quick check in, reasonable."

CA $111

CA $126 total

includes taxes & fees

Oct 15 - Oct 16

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sunbeam-Motel.h9520604.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/10000/2800/2779/2215a2c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2800/2779/5e3505c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/10000/2800/2779/8d5b8366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/2800/2779/a4b18a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### University Inn

1.3 km from Sierra Vista Regional Medical Center

8.0/10

Very good

(1006)

"Nice clean place near restaurants and the college. Staff was great!"

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-University-Inn.h2779.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/910000/901600/901557/f012dd57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/901600/901557/003610ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/910000/901600/901557/f3525962.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![40-inch flat-screen TV with cable channels](https://images.trvl-media.com/lodging/1000000/910000/901600/901557/48dcf176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Buena Vista

1.4 km from Sierra Vista Regional Medical Center

8.2/10

Very good

(856)

"Super easy check in and enjoyed my stay"

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Buena-Vista.h901557.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/b3e0f714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, Multiple Beds, Kitchen](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/b7784842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, Multiple Beds, Kitchen | Private kitchen](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/ee1d2d73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/7c513494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sands Inn & Suites

1.4 km from Sierra Vista Regional Medical Center

8.0/10

Very good

(373)

"This place was spacious and super clean. Would stay again "

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sands-Inn-Suites.h2202688.Hotel-Information)

![Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/ec6a1c5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/4fde0a7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/36e3cc0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/ea926815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Avenue Inn Downtown San Luis Obispo

2 km from Sierra Vista Regional Medical Center

9.0/10

Wonderful

(1106)

"Great location, smaller room but nice facilities."

CA $104

CA $119 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Avenue-Inn-Downtown-San-Luis-Obispo.h67485.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/582169ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/e3169684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Spa](https://images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/bb3d241b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/368c910b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Inn at San Luis Obispo

1.4 km from Sierra Vista Regional Medical Center

7.6/10

Good

(1010)

"awesome place "

CA $87

CA $99 total

includes taxes & fees

Nov 10 - Nov 11

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Inn-At-San-Luis-Obispo.h12356430.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/f50d5d30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Double Beds, Non Smoking, Mountain View | Bathroom](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/822ae52d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/ad148dfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/0243af7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mission Inn San Luis Obispo

1.5 km from Sierra Vista Regional Medical Center

7.8/10

Good

(877)

"Good value for the price compared to the other adjacent properties. "

CA $238

CA $286 total

includes taxes & fees

Oct 18 - Oct 19

[](https://www.expedia.ca/San-Luis-Obispo-Hotels-Mission-Inn-San-Luis-Obispo.h123502.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27&regionId=553248621560543927&adults=2&sort=RECOMMENDED&openPlayBack=true)

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[Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSierra-Vista-Regional-Medical-Center-Hotels.0-l553248621560543927-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSierra-Vista-Regional-Medical-Center-Hotels.0-l553248621560543927-0.Travel-Guide-Filter-Hotels)

## Top Sierra Vista Regional Medical Center Hotel Reviews

![Hotel Buena Vista](//images.trvl-media.com/lodging/1000000/910000/901600/901557/f012dd57_y.jpg)

### Hotel Buena Vista

10/10 Excellent

"Older hotel with updated features. Nice, clean, and comfy. Conveniently located, great for a quick family trip or stay over."

[](https://expedia.ca/San-Luis-Obispo-Hotels-Hotel-Buena-Vista.h901557.Hotel-Information)

![La Cuesta Inn, BW Signature Collection](//images.trvl-media.com/lodging/1000000/20000/14400/14372/f5b74a44_y.jpg)

### La Cuesta Inn, BW Signature Collection

10/10 Excellent

"Better front desk snacks would be nice. "

[](https://expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information)

![Inn at San Luis Obispo](//images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/582169ce_y.jpg)

### Inn at San Luis Obispo

10/10 Excellent

"Welcoming "

[](https://expedia.ca/San-Luis-Obispo-Hotels-Inn-At-San-Luis-Obispo.h12356430.Hotel-Information)

![Hotel San Luis Obispo](//images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/f3abfe0f_y.jpg)

### Hotel San Luis Obispo

10/10 Excellent

"The location was great for access to downtown SLO and the rooms are spacious. Nice amenities such as robes, slippers, water and coffee. The staff were friendly and helpful. One suggestion is to avoid room facing the pool. There’s some area not in the hotel that seems to play music most of the day and you can hear it. "

[](https://expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information)

![Avenue Inn Downtown San Luis Obispo](//images.trvl-media.com/lodging/1000000/70000/67500/67485/ec6a1c5f_y.jpg)

### Avenue Inn Downtown San Luis Obispo

10/10 Excellent

"Nice place and affordable "

[](https://expedia.ca/San-Luis-Obispo-Hotels-Avenue-Inn-Downtown-San-Luis-Obispo.h67485.Hotel-Information)

![La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown](//images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/99fa5dc7_y.jpg)

### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

10/10 Excellent

"Clean, great breakfast, comfortable beds, large workout room"

[](https://expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information)

![The Wayfarer San Luis Obispo, Tapestry Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/20000/19984/03ecb72d_y.jpg)

### The Wayfarer San Luis Obispo, Tapestry Collection by Hilton

10/10 Excellent

"Nice quit clean welcoming hotel "

[](https://expedia.ca/San-Luis-Obispo-Hotels-The-Wayfarer-San-Luis-Obispo.h19984.Hotel-Information)

![Quality Suites Downtown San Luis Obispo](//images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291_y.jpg)

### Quality Suites Downtown San Luis Obispo

10/10 Excellent

"Nice "

[](https://expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information)

![Madonna Inn](//images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg)

### Madonna Inn

10/10 Excellent

"We stayed in the honeymoon suite and it was definitely worth it"

[](https://expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information)

## Hotels near other Sierra Vista Regional Medical Center attractions

[](https://www.expedia.ca/Santa-Rosa-Park-Hotels.0-l553248635118923043-0.Travel-Guide-Filter-Hotels)

![SanLuisObispo_SantaRosaPark_553248635118923043_01](https://images.trvl-media.com/place/553248635118923043/ed849bbb-c7aa-4534-8fca-765959e55240.jpg)

### Santa Rosa Park

After visiting Santa Rosa Park, make a plan to see the other sights and activities in San Luis Obispo. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635118923043)

[](https://www.expedia.ca/Alex-G-Spanos-Stadium-Hotels.0-l6089189-0.Travel-Guide-Filter-Hotels)

![SanLuisObispo_AlexGSpanosStadium_6089189_02](https://images.trvl-media.com/place/6089189/8ed898b9-63e4-40a9-864a-4d34a3d4d975.jpg)

### Alex G. Spanos Stadium

Catch an event at Alex G. Spanos Stadium, and enjoy other activities in San Luis Obispo such as biking. Discover the beautiful sunsets and top-notch restaurants in this family-friendly area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6089189)

[](https://www.expedia.ca/California-Polytechnic-State-University-Hotels.0-l6063425-0.Travel-Guide-Filter-Hotels)

![SanLuisObispo_CaliforniaPolytechnicStateUniversity_6063425_06](https://images.trvl-media.com/place/6063425/bd4f943a-5356-45b6-8d12-9a135733567b.jpg)

### California Polytechnic State University, San Luis Obispo

4.6/5 (1,257 reviews)

Explore the campus of California Polytechnic State University, San Luis Obispo during your visit to San Luis Obispo. Stroll along the area's seaside, or simply savor its top-notch restaurants.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6063425)

[](https://www.expedia.ca/San-Luis-Obispo-County-Library-Hotels.0-l553248621555611788-0.Travel-Guide-Filter-Hotels)

![SanLuisObispo_SanLuisObispoCountyLibrary_553248621555611788_01](https://images.trvl-media.com/place/553248621555611788/4e3fbeed-6fda-4ef8-8253-d99f7ba83011.jpg)

### San Luis Obispo County Library

After visiting San Luis Obispo County Library, make a plan to see the other sights and activities in San Luis Obispo. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621555611788)

[](https://www.expedia.ca/Fremont-Theater-Hotels.0-l6089183-0.Travel-Guide-Filter-Hotels)

![An amazing Art Deco preserved movie theatre. #Details](https://images.trvl-media.com/place/6046822/bb2b89d1-2195-4492-ae45-9d7974c324b8.jpg)

Photo by Marjorie Stevens

### Fremont Theater

4.1/5 (119 reviews)

You can make plans for a show at Fremont Theater on your trip to San Luis Obispo. Wander the beautiful beaches or discover the area's beautiful sunsets.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6089183)

[](https://www.expedia.ca/Robert-A-Mott-Athletics-Center-Hotels.0-l693562773884764160-0.Travel-Guide-Filter-Hotels)

### Robert A. Mott Athletics Center

Catch an event at Robert A. Mott Athletics Center during your trip to San Luis Obispo. Discover the area's charming cafes and its acclaimed theater scene.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=693562773884764160)

[](https://www.expedia.ca/Performing-Arts-Center-Hotels.0-l553248621556207176-0.Travel-Guide-Filter-Hotels)

### Performing Arts Center

You can enjoy a show at Performing Arts Center during your stay in San Luis Obispo. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621556207176)

[](https://www.expedia.ca/San-Luis-Obispo-Little-Theatre-Hotels.0-l553248621532640004-0.Travel-Guide-Filter-Hotels)

### San Luis Obispo Little Theatre

You can make plans for a show at San Luis Obispo Little Theatre on your trip to San Luis Obispo. Discover the beautiful sunsets in this family-friendly area, or enjoy its biking trails.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532640004)

## Frequently asked questions

### What's the area like around Sierra Vista Regional Medical Center?

> Sierra Vista Regional Medical Center is located in a family-friendly area of San Luis Obispo known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 53 hotels and other accommodations you'll find within a mile.

### What's the best hotel to stay near Sierra Vista Regional Medical Center?

> [Quality Suites Downtown San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.8 mi (1.3 km) from Sierra Vista Regional Medical Center. Other good choices within a short distance include [Apple Farm](https://www.expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) and [La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information).

### How many hotels will I be able to find close to Sierra Vista Regional Medical Center?

> Expedia has 53 hotels and other accommodations within a mile from Sierra Vista Regional Medical Center.

### If I need to cancel the hotel reservation for my stay near Sierra Vista Regional Medical Center, will I receive a refund?

> Yes! Most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals available near Sierra Vista Regional Medical Center.

### What can I see and do near Sierra Vista Regional Medical Center?

> You'll want to browse the collections at History Center of San Luis Obispo County, San Luis Obispo Museum of Art, and San Luis Obispo Railroad Museum. Fremont Theater, Ah Louis Store, and Dallidet Adobe and Gardens are notable landmarks to explore if you're in the area. You can check out the local talent at Performing Arts Center, San Luis Obispo Little Theatre, and Sunset Drive-In Theatre.

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-   [Beach Hotel Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Beach-Hotel.0-0-d6046822-tBeachHotel.Travel-Guide-Filter-Hotels)
-   [Boutique Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Boutique-Hotel.0-0-d6046822-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
-   [Business Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Business-Hotel.0-0-d6046822-tBusinessHotel.Travel-Guide-Filter-Hotels)
-   [Casino Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Casino-Hotel.0-0-d6046822-tCasinoHotel.Travel-Guide-Filter-Hotels)
-   [Cheap Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Cheap-Hotels.0-0-d6046822-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Family Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Family-Hotel.0-0-d6046822-tFamilyHotel.Travel-Guide-Filter-Hotels)
-   [Golf Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Golf-Hotel.0-0-d6046822-tGolfHotel.Travel-Guide-Filter-Hotels)
-   [Historic Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Historic-Hotel.0-0-d6046822-tHistoricHotel.Travel-Guide-Filter-Hotels)
-   [Honeymoon Resorts and in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Honeymoon-Hotels.0-0-d6046822-tHoneymoonHotels.Travel-Guide-Filter-Hotels)
-   [Hotels with a Pool in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-With-Pool.0-0-d6046822-tHotelwithPool.Travel-Guide-Filter-Hotels)
-   [Hotels with Balconies in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotels-With-Balconies.0-0-d6046822-tHotelswithBalconies.Travel-Guide-Filter-Hotels)
-   [Hotels with Free Airport Shuttle in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d6046822-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels)
-   [Hotels with an Indoor Pool in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotels-With-Indoor-Pool.0-0-d6046822-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels)
-   [Hotels with Kitchenettes in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotels-With-Kitchenettes.0-0-d6046822-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels)
-   [Hotels with Tennis Courts in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotels-With-Tennis-Courts.0-0-d6046822-tHotelswithTennisCourts.Travel-Guide-Filter-Hotels)
-   [Lgbt Friendly Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-LGBT-Friendly-Hotel.0-0-d6046822-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Luxury Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Luxury-Hotel.0-0-d6046822-tLuxuryHotel.Travel-Guide-Filter-Hotels)
-   [Mountain Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Mountain-Hotels.0-0-d6046822-tMountainHotels.Travel-Guide-Filter-Hotels)
-   [Oceanfront Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Oceanfront-Hotels.0-0-d6046822-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
-   [Pacifica Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Pacifica-Hotels.0-0-d6046822--bPacificaHotels.Travel-Guide-Filter-Hotels)
-   [Pet-Friendly Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Pet-Friendly-Hotel.0-0-d6046822-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Spa Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Spa-Hotel.0-0-d6046822-tSpaHotel.Travel-Guide-Filter-Hotels)
-   [Waterpark Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Waterpark-Hotels.0-0-d6046822-tWaterparkHotels.Travel-Guide-Filter-Hotels)
-   [Hotel Wedding Venues Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Wedding-Hotels.0-0-d6046822-tWeddingHotels.Travel-Guide-Filter-Hotels)
-   [Winery Hotels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Hotels-Winery-Hotel.0-0-d6046822-tWineryHotel.Travel-Guide-Filter-Hotels)
-   [San Luis Obispo Hotels](https://www.expedia.ca/San-Luis-Obispo-Hotels.d6046822.Travel-Guide-Hotels)
-   [Hotels near San Luis Obispo Little Theatre](https://www.expedia.ca/San-Luis-Obispo-Little-Theatre-Hotels.0-l553248621532640004-0.Travel-Guide-Filter-Hotels)
-   [Motels in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Motels.d6046822-aaMotels.Travel-Guide-Accommodation)
-   [Resorts in San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Resort-Hotels.d6046822-aaResortHotels.Travel-Guide-Accommodation)
-   [Hotels near San Luis Obispo Station](https://www.expedia.ca/San-Luis-Obispo-Station-Hotels.d6194810.Travel-Guide-Hotels)
-   [Hotels near San Luis Obispo Superior Court](https://www.expedia.ca/San-Luis-Obispo-Superior-Court-Hotels.0-l553248621560543921-0.Travel-Guide-Filter-Hotels)
-   [San Luis Obispo Wine Country Hotels](https://www.expedia.ca/San-Luis-Obispo-Wine-Country-Hotels.d553248621593965865.Travel-Guide-Hotels)
-   [Shell Beach Hotels](https://www.expedia.ca/Shell-Beach-Pismo-Beach-Hotels.0-n55961-0.Travel-Guide-Filter-Hotels)
-   [Sunset Palisades Hotels](https://www.expedia.ca/Sunset-Palisades-Pismo-Beach-Hotels.0-n553248635976479350-0.Travel-Guide-Filter-Hotels)
-   [Hotels near The Spa at Dolphin Bay](https://www.expedia.ca/The-Spa-At-Dolphin-Bay-Hotels.0-l553248621532639992-0.Travel-Guide-Filter-Hotels)

-   [Flights to San Luis Obispo](https://www.expedia.ca/Cheap-Flights-To-San-Luis-Obispo.d6046822.Travel-Guide-Flights)
-   [Flights from San Luis Obispo](https://www.expedia.ca/lp/flights/6046822/flights-from-san-luis-obispo)

-   [Mission San Luis Obispo de Tolosa](https://www.expedia.ca/Mission-San-Luis-Obispo-De-Tolosa-Downtown-San-Luis-Obispo.d6089181.Vacation-Attraction)
-   [Visit Downtown San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo-Downtown-San-Luis-Obispo.dx553248635976479118)
-   [San Luis Obispo Vacations](https://www.expedia.ca/San-Luis-Obispo.d6046822.Destination-Travel-Guides)
-   [Visit San Luis Obispo](https://www.expedia.ca/San-Luis-Obispo.dx6046822)

-   [Car rental San Luis Obispo](https://www.expedia.ca/Car-Rentals-In-San-Luis-Obispo.d6046822.Car-Rental-Guide)

-   [San Luis Obispo Vacation Rentals](https://www.expedia.ca/San-Luis-Obispo-Vacation-Rentals.d6046822.Travel-Guide-VacationRentals)

-   [Things to do in San Luis Obispo](https://www.expedia.ca/Things-To-Do-In-San-Luis-Obispo.d6046822.Travel-Guide-Activities)