Title: The 10 Best Hotels Near Sierra Vista Regional Medical Center, San Luis Obispo from CA $93 | Expedia.ca [Foothill Travel Guide](https://expedia.ca/San-Luis-Obispo-Foothill.dx896141079926198272)[Sierra Vista Regional Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Sierra-Vista-Regional-Medical-Center.d553248621560543927.Car-Rental-Guide)[Sierra Vista Regional Medical Center Vacations](https://expedia.ca/Sierra-Vista-Regional-Medical-Center-Foothill.d553248621560543927.Vacation-Attraction) ![SanLuisObispo_SierraVistaRegionalMedicalCenter_553248621560543927_05](https://images.trvl-media.com/place/553248621560543927/2b263ee2-026f-4c4c-9957-3138d4a9edaa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Sierra Vista Regional Medical Center, San Luis Obispo from CA $93 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=553248621560543927&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=553248621560543927&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248621560543927&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248621560543927&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Sierra Vista Regional Medical Center hotels ![Terrace/patio](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/fd8ba1ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/0b48154e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed | Living area](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/afc93282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/cb924494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Petit Soleil [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Petit-Soleil.h102995602.Hotel-Information) MoJo, 1.3 km from Sierra Vista Regional Medical Center 9.8/10 Exceptional (274) "Clean and comfy rooms." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Michelle CA $185 CA $210 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Petit-Soleil.h102995602.Hotel-Information) ![Outdoor pool, open 10:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/b42da2cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/4d8de4d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/95b309ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Suites Downtown San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) 1.3 km from Sierra Vista Regional Medical Center 9.4/10 Exceptional (1296) "Value for money, location, and two room configuration is excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $163 CA $213 total includes taxes & fees Jan 13 - Jan 14, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/088fc1a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/3f29ecb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/bdb8f309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Morro Suite | Living area](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) Downtown San Luis Obispo, 1.3 km from Sierra Vista Regional Medical Center 9.4/10 Exceptional (548) "Beautiful room and nice rooftop bar!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chizuru CA $408 CA $463 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1054700/1054670/1ddc5743.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1060000/1054700/1054670/350ca783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/2000000/1060000/1054700/1054670/29a06016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1060000/1054700/1054670/11ba2762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Luis Creek Lodge [](https://www.expedia.ca/San-Luis-Obispo-Hotels-San-Luis-Creek-Lodge.h1054670.Hotel-Information) 1.4 km from Sierra Vista Regional Medical Center 9.4/10 Exceptional (1004) "Beautiful cozy room, great staff, good location, clean and modern. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rasa CA $191 CA $243 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-San-Luis-Creek-Lodge.h1054670.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/7399029a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/2bdb5b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/a3615cf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5540000/5531300/5531224/c28bd6d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Granada Hotel & Bistro [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Granada-Hotel-Bistro.h5531224.Hotel-Information) Downtown San Luis Obispo, 1.5 km from Sierra Vista Regional Medical Center 9.2/10 Wonderful (802) "Excellent service. Rooms were beautiful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria Esther Nicole CA $255 CA $290 total includes taxes & fees Jan 14 - Jan 15, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Granada-Hotel-Bistro.h5531224.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/22fcbd4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/e0c265d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/42ac20df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/8a3ff3f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CERRO, Autograph Collection [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) Downtown San Luis Obispo, 1.6 km from Sierra Vista Regional Medical Center 9.2/10 Wonderful (468) "We had a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ADALBERT CA $253 CA $335 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/0fb1832a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily cooked-to-order breakfast](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/4091ad0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 Queen Bed](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/35aa9a41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/26000000/25840000/25838300/25838284/9702c09d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden Street Inn, A Kirkwood Collection Hotel [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Garden-Street-Inn.h25838284.Hotel-Information) Downtown San Luis Obispo, 1.7 km from Sierra Vista Regional Medical Center 9.2/10 Wonderful (722) "Very nice place. Comfortable and clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) richard CA $200 CA $227 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Garden-Street-Inn.h25838284.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/99fa5dc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/d0e886ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/d050f4c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/51fe5539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown [](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) 1.4 km from Sierra Vista Regional Medical Center 9.0/10 Wonderful (1804) "Staff was very friendly. Room was clean and location was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $158 CA $180 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/3327b2cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/a309b8f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/a70e012f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/a7600fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wayfarer San Luis Obispo, Tapestry Collection by Hilton [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Wayfarer-San-Luis-Obispo.h19984.Hotel-Information) 1.3 km from Sierra Vista Regional Medical Center 9.0/10 Wonderful (1000) "Great location and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $154 CA $181 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Wayfarer-San-Luis-Obispo.h19984.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/880cde75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/1e66a09e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/462ce0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apple Farm [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) 1.5 km from Sierra Vista Regional Medical Center 9.0/10 Wonderful (1571) "Love the rooms, great atmosphere for a fun trip. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) R CA $111 CA $165 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/ec6a1c5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/4fde0a7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/36e3cc0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/17b80a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avenue Inn Downtown San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Avenue-Inn-Downtown-San-Luis-Obispo.h67485.Hotel-Information) Lower Higuera, 2 km from Sierra Vista Regional Medical Center 9.0/10 Wonderful (1134) "Good room, nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) annamalai CA $99 CA $113 total includes taxes & fees Jan 13 - Jan 14, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Avenue-Inn-Downtown-San-Luis-Obispo.h67485.Hotel-Information) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/45433961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/63206dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Madonna Suite | Bathroom](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/a4e68773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madonna Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) 3 km from Sierra Vista Regional Medical Center 9.2/10 Wonderful (1328) "Great place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caeli CA $189 CA $262 total includes taxes & fees Jan 13 - Jan 14, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/ab6971ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/a36ab0c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/8aa04456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/34824bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cuesta Inn, BW Signature Collection [](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information) 1.4 km from Sierra Vista Regional Medical Center 8.8/10 Excellent (1080) "Clean room, nice staff, good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Irene CA $160 CA $181 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/2000000/1160000/1151800/1151757/45830d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1160000/1151800/1151757/fcd86481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/2000000/1160000/1151800/1151757/0a965bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/2000000/1160000/1151800/1151757/fa728569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peach Tree Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Peach-Tree-Inn.h1151757.Hotel-Information) 1.4 km from Sierra Vista Regional Medical Center 8.8/10 Excellent (1000) "Very cordial staff, great rooms and location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chad CA $123 CA $149 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Peach-Tree-Inn.h1151757.Hotel-Information) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520604/b76c2fa4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520604/a02c42f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520604/30d40c6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Bathroom](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520604/9f863d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunbeam Motel [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sunbeam-Motel.h9520604.Hotel-Information) 1.3 km from Sierra Vista Regional Medical Center 8.2/10 Very good (757) "Had a great stay. Very communicative. Great and comfortable rooms. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Toby CA $99 CA $113 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sunbeam-Motel.h9520604.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/910000/901600/901557/f012dd57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/901600/901557/003610ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/910000/901600/901557/272e6eb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/910000/901600/901557/be9d82c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Buena Vista [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Buena-Vista.h901557.Hotel-Information) 1.4 km from Sierra Vista Regional Medical Center 8.2/10 Very good (881) "The staff was very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tomiyasu [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Buena-Vista.h901557.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/10000/2800/2779/2215a2c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/2800/2779/a544bde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/10000/2800/2779/8d5b8366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/2800/2779/16bfa6a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### University Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-University-Inn.h2779.Hotel-Information) 1.3 km from Sierra Vista Regional Medical Center 8.0/10 Very good (1001) "love the place close to everything and very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) eduardo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-University-Inn.h2779.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/7c513494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/b3e0f714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Multiple Beds, Kitchen](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/4fd722dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/040df98c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sands Inn & Suites [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sands-Inn-Suites.h2202688.Hotel-Information) 1.4 km from Sierra Vista Regional Medical Center 8.0/10 Very good (444) "Great time " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marissa [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sands-Inn-Suites.h2202688.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/f50d5d30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking, Mountain View | Bathroom](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/2c1008e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Mountain View](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/aa0be56d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mountain view](https://images.trvl-media.com/lodging/1000000/130000/123600/123502/ed30dacd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mission Inn San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Mission-Inn-San-Luis-Obispo.h123502.Hotel-Information) 1.5 km from Sierra Vista Regional Medical Center 7.8/10 Good (898) "room was very clean and staff very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonia CA $86 CA $113 total includes taxes & fees Jan 10 - Jan 11, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Mission-Inn-San-Luis-Obispo.h123502.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/e3169684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/698025ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/dc659891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/13000000/12360000/12356500/12356430/fe6547ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn at San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Inn-At-San-Luis-Obispo.h12356430.Hotel-Information) 1.4 km from Sierra Vista Regional Medical Center 7.6/10 Good (1002) "The Inn was a terrific location for a visit to Cal Poly. The hotel was quiet and clean and a good value. We would definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig CA $82 CA $93 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Inn-At-San-Luis-Obispo.h12356430.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29®ionId=553248621560543927&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Sierra Vista Regional Medical Center Hotel Reviews ![Apple Farm](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg) ### Apple Farm 10/10 Excellent "Beautiful location and lovely rooms! Enjoy " [](https://expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Petit Soleil](https://images.trvl-media.com/lodging/103000000/103000000/102995700/102995602/881d3938_y.jpg) ### Petit Soleil 10/10 Excellent "Rooms recently remodeled, clean with large screen tv." [](https://expedia.ca/San-Luis-Obispo-Hotels-Petit-Soleil.h102995602.Hotel-Information) ![La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/99fa5dc7_y.jpg) ### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown 10/10 Excellent "great" [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) ![Madonna Inn](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "Always such a joy" [](https://expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Sands Inn & Suites](https://images.trvl-media.com/lodging/3000000/2210000/2202700/2202688/b3e0f714_y.jpg) ### Sands Inn & Suites 10/10 Excellent "Bed very comfortable and a very beautiful room." [](https://expedia.ca/San-Luis-Obispo-Hotels-Sands-Inn-Suites.h2202688.Hotel-Information) ![Quality Suites Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291_y.jpg) ### Quality Suites Downtown San Luis Obispo 10/10 Excellent "The suites were very spacious and the beds comfortable, even the pull out. The location is excellent. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ![La Cuesta Inn, BW Signature Collection](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/f5b74a44_y.jpg) ### La Cuesta Inn, BW Signature Collection 10/10 Excellent "Staff, clean, hot shower" [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information) ![The Wayfarer San Luis Obispo, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/20000/19984/03ecb72d_y.jpg) ### The Wayfarer San Luis Obispo, Tapestry Collection by Hilton 10/10 Excellent "Clean room and excellent staff " [](https://expedia.ca/San-Luis-Obispo-Hotels-The-Wayfarer-San-Luis-Obispo.h19984.Hotel-Information) ![Hotel San Luis Obispo](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871_y.jpg) ### Hotel San Luis Obispo 10/10 Excellent "Staff very nice, understanding and Helpful" [](https://expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) ## Hotels near other Sierra Vista Regional Medical Center attractions ![SanLuisObispo_SantaRosaPark_553248635118923043_04](https://images.trvl-media.com/place/553248635118923043/aa4f8f03-ea1b-4348-8e60-5a0ddda0e582.jpg) ### Santa Rosa Park After visiting Santa Rosa Park, make a plan to see the other sights and activities in San Luis Obispo. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635118923043) ![SanLuisObispo_AlexGSpanosStadium_6089189_02](https://images.trvl-media.com/place/6089189/8ed898b9-63e4-40a9-864a-4d34a3d4d975.jpg) ### Alex G. Spanos Stadium Catch an event at Alex G. Spanos Stadium, and enjoy other activities in San Luis Obispo such as biking. Discover the beautiful sunsets and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6089189) ![SanLuisObispo_CaliforniaPolytechnicStateUniversity_6063425_06](https://images.trvl-media.com/place/6063425/bd4f943a-5356-45b6-8d12-9a135733567b.jpg) ### California Polytechnic State University, San Luis Obispo 4.6/5 (1,257 reviews) Explore the campus of California Polytechnic State University, San Luis Obispo during your visit to San Luis Obispo. Stroll along the area's seaside, or simply savor its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6063425) ![SanLuisObispo_SanLuisObispoCountyLibrary_553248621555611788_01](https://images.trvl-media.com/place/553248621555611788/4e3fbeed-6fda-4ef8-8253-d99f7ba83011.jpg) ### San Luis Obispo County Library After visiting San Luis Obispo County Library, make a plan to see the other sights and activities in San Luis Obispo. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621555611788) ![Fremont Theatre in San Luis Obispo, California - #ArtDeco #architecture](https://images.trvl-media.com/place/6046822/71a9e6f1-5b80-4352-be43-c30f43c01082.jpg) Photo by Marjorie Stevens ### Fremont Theater 4.1/5 (119 reviews) You can make plans for a show at Fremont Theater on your trip to San Luis Obispo. Wander the beautiful beaches or discover the area's beautiful sunsets. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6089183) ### Robert A. Mott Athletics Center Catch an event at Robert A. Mott Athletics Center during your trip to San Luis Obispo. Discover the area's wineries and its acclaimed art scene. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=693562773884764160) ### Performing Arts Center You can enjoy a show at Performing Arts Center during your stay in San Luis Obispo. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621556207176) ### San Luis Obispo Little Theatre You can make plans for a show at San Luis Obispo Little Theatre on your trip to San Luis Obispo. Discover the beautiful sunsets in this family-friendly area, or enjoy its biking trails. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532640004) ## Frequently asked questions ### What's the area like around Sierra Vista Regional Medical Center? ### What's the best hotel to stay near Sierra Vista Regional Medical Center? ### How many hotels will I be able to find close to Sierra Vista Regional Medical Center? ### If I need to cancel the hotel reservation for my stay near Sierra Vista Regional Medical Center, will I receive a refund? ### What can I see and do near Sierra Vista Regional Medical Center? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [4 Star Hotels in San Luis Obispo ](https://www.expedia.ca/4Star-San-Luis-Obispo-Hotels.s40-0-d6046822.Travel-Guide-Filter-Hotels) - [Hotels near Avila Beach Golf Resort ](https://www.expedia.ca/Avila-Beach-Golf-Resort-Hotels.0-l6185491-0.Travel-Guide-Filter-Hotels) - [Hotels near Avila Beach ](https://www.expedia.ca/Avila-Beach-Hotels.0-l712618179538735104-0.Travel-Guide-Filter-Hotels) - 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