Title: Book the Best BUSINESS Hotels in Serrano in 2025 | Expedia.ca [Serrano Travel Guide](https://expedia.ca/Bonita-Springs-Serrano.dx553248635976473313)[Vacation Rentals in Bonita Springs](https://expedia.ca/Bonita-Springs-Vacation-Rentals.d6403.Travel-Guide-VacationRentals)[Flights to Bonita Springs](https://expedia.ca/Cheap-Flights-To-Bonita-Springs.d6403.Travel-Guide-Flights)[Things to do in Bonita Springs](https://expedia.ca/Things-To-Do-In-Bonita-Springs.d6403.Travel-Guide-Activities)[Serrano Car Rentals](https://expedia.ca/Car-Rentals-In-Serrano.d553248635976473313.Car-Rental-Guide)[Serrano Vacations](https://expedia.ca/Serrano.d553248635976473313.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Serrano, FL from CA $97 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Serrano Business Hotels Tonight [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=553248635976473313&startDate=2025-09-29&endDate=2025-09-30&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976473313&startDate=2025-09-30&endDate=2025-10-01&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976473313&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976473313&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Serrano Business Hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/a9620a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/d254153a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/a0f722c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/bb6d486e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Trianon Bonita Bay Bonita Bay 9.2/10 Wonderful (1678) "Great location , very nice place , good restaurants" CA $98 CA $110 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Naples-Hotels-Trianon-Bonita-Bay.h40858.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/159000/158967/2bbde5c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/160000/159000/158967/fbf201ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/160000/159000/158967/ec833164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/159000/158967/1d4afbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Bonita Springs Naples N. Bonita Shores 9.0/10 Wonderful (1154) "Spacious room, very clean, and friendly staff." CA $127 CA $142 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Naples-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Bonita-Springs-Naples-N.h158967.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/49000000/48990000/48980100/48980077/98e32444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/49000000/48990000/48980100/48980077/00a97ad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/49000000/48990000/48980100/48980077/2da48eb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/49000000/48990000/48980100/48980077/e26fbeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Fort Myers Airport by IHG Daniels Corridor 9.6/10 Exceptional (1011) "Great place to stay." CA $130 CA $145 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Fort-Myers-Southeast.h48980077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102600/102510/9ccc434b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/110000/102600/102510/8f3834e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102600/102510/3cfa5c53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/110000/102600/102510/39f96720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Naples South I-75 by IHG Rural Estates 8.8/10 Excellent (719) "Very clean and family friendly " CA $121 CA $135 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Naples-Hotels-Holiday-Inn-Express-Naples-South-I-75.h102510.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/83cb6bb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/e00a9bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/2c14a98f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/432e75cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Fort Myers Sanibel Fort Myers 8.6/10 Excellent (1010) "We loved the staff attitude and the excellent breakfast." CA $121 CA $135 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Fort-Myers-Hotels-Residence-Inn-By-Marriott-Fort-Myers-Sanibel.h2625745.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/890000/890000/889926/59782bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/890000/890000/889926/a82503c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/890000/890000/889926/a3379f7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/890000/890000/889926/d8c9e7db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel Naples Downtown - 5th Avenue East Naples 9.0/10 Wonderful (1016) "Very nice Hotel, for a quick getaway" CA $84 CA $97 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Naples-Hotels-Holiday-Inn-Express-Hotel-Suites-Naples-Downtown-5th-Ave.h889926.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/60000000/59670000/59660600/59660502/4c6b3377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/60000000/59670000/59660600/59660502/23a6ac26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/60000000/59670000/59660600/59660502/256ff2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, memory foam beds, desk](https://images.trvl-media.com/lodging/60000000/59670000/59660600/59660502/79660a63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Bonita Springs Bonita Springs 9.2/10 Wonderful (423) "Great stay. " CA $138 CA $154 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Naples-Hotels-Fairfield-Inn-Suites-By-Marriott-Bonita-Springs.h59660502.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96930000/96929600/96929542/a2675737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/97000000/96930000/96929600/96929542/9b2fb814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/97000000/96930000/96929600/96929542/d68596bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Studio, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/97000000/96930000/96929600/96929542/ce7db9d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Premier Suites - Fort Myers - Airport Daniels Corridor 8.8/10 Excellent (699) "Great place to stay nice and clean" CA $95 CA $106 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Fort-Myers-Hotels-Extended-Stay-America-Premier-Suites-Fort-Myers-Airport.h96929542.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/26500/26474/37900b17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26500/26474/83d91e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26500/26474/71e2403e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard room with two double beds](https://images.trvl-media.com/lodging/1000000/30000/26500/26474/268480b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Naples Central Central Naples 8.6/10 Excellent (1013) "Family hotel, recommended" CA $113 CA $126 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Naples-Hotels-Hampton-Inn-Naples-Central.h26474.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/a69cd385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/9ecc1017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/fe3aa003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/088bfb58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG Fort Myers Beach 9.4/10 Exceptional (1005) "Easy to get to, easy check in, pleasant staff, good breakfast, easy checkout, clean rooms." CA $127 CA $141 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-13&endDate=2025-10-14®ionId=553248635976473313&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Serrano Hotel Reviews ![La Quinta Inn & Suites by Wyndham Naples Downtown](//images.trvl-media.com/lodging/1000000/30000/24700/24612/1d33d843_y.jpg) ### La Quinta Inn & Suites by Wyndham Naples Downtown 10/10 Excellent "Everything was fine" [](https://expedia.ca/Naples-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Naples-Downtown.h24612.Hotel-Information) ![The Ritz-Carlton, Naples](//images.trvl-media.com/lodging/1000000/20000/10500/10494/88b021de_y.jpg) ### The Ritz-Carlton, Naples 10/10 Excellent "Wonderful stay" [](https://expedia.ca/Naples-Hotels-The-Ritz-Carlton.h10494.Hotel-Information) ![Hyatt House Naples/5th Avenue](//images.trvl-media.com/lodging/13000000/12810000/12805400/12805323/b4e7afd1_y.jpg) ### Hyatt House Naples/5th Avenue 10/10 Excellent "Friendly staff, nice rooms very clean hotel" [](https://expedia.ca/Naples-Hotels-Hyatt-House-Naples5th-Avenue.h12805323.Hotel-Information) ![Sanibel Island Beach Resort](//images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Beach access, rooms clean. Had a family with small children next to our room. If the stay is for adults only, maybe put families in another area or adults too." [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Naples Grande Beach Resort](//images.trvl-media.com/lodging/1000000/20000/15900/15898/65da812e_y.jpg) ### Naples Grande Beach Resort 10/10 Excellent "Beautiful hotel with friendly staff. Room was clean and comfortable. Fitness center is massive and nicely kept. Grounds and amenities are beautiful. We will be back for a longer stay next time we are in the area. Thanks for everything. " [](https://expedia.ca/Naples-Hotels-Naples-Grande-Beach-Resort.h15898.Hotel-Information) ![Bayfront Inn Fifth Avenue](//images.trvl-media.com/lodging/1000000/30000/22800/22721/a0622d4c_y.jpg) ### Bayfront Inn Fifth Avenue 10/10 Excellent "Great service. Great location. Very clean. " [](https://expedia.ca/Naples-Hotels-Bayfront-Inn-Fifth-Avenue.h22721.Hotel-Information) ![Compass by Margaritaville Hotel Naples](//images.trvl-media.com/lodging/1000000/550000/543700/543614/16d35331_y.jpg) ### Compass by Margaritaville Hotel Naples 10/10 Excellent "Perfect" [](https://expedia.ca/Naples-Hotels-Compass-By-Margaritaville-Naples.h543614.Hotel-Information) ![Lani Kai Beachfront Resort](//images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "Love the property, parking not so much. " [](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Inn on Fifth](//images.trvl-media.com/lodging/1000000/90000/85000/84910/7138f29c_y.jpg) ### Inn on Fifth 10/10 Excellent "The only thing that was not perfect is that they are valet only. I don’t prefer that as my wife and I prefer to go in and out pretty regularly." 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[Luxury Hotels in Southeast Florida](https://www.expedia.ca/Southeast-Florida-Hotels-Luxury-Hotel.0-0-d6047949-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Southeast Florida](https://www.expedia.ca/Southeast-Florida-Hotels-Oceanfront-Hotels.0-0-d6047949-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Florida](https://www.expedia.ca/Southeast-Florida-Hotels-Romantic-Hotel.0-0-d6047949-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Scuba Diving Hotels in Southeast Florida](https://www.expedia.ca/Southeast-Florida-Hotels-Scuba-Diving-Vacations.0-0-d6047949-tscubadivingvacations.Travel-Guide-Filter-Hotels) - [Spa Hotels in Southeast Florida](https://www.expedia.ca/Southeast-Florida-Hotels-Spa-Hotel.0-0-d6047949-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Southeast Florida](https://www.expedia.ca/Southeast-Florida-Hotels-Waterpark-Hotels.0-0-d6047949-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Hotels with Bar in Venice](https://www.expedia.ca/Venice-Hotels-Hotels-With-Bar.0-0-d10285-tHotelswithBar.Travel-Guide-Filter-Hotels) - 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