Title: 10 Best Hotels in Serra Mesa, San Diego for 2025 | Expedia.ca [Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Serra Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Serra-Mesa.d553248635953501652.Car-Rental-Guide)[Serra Mesa Vacations](https://expedia.ca/Serra-Mesa.d553248635953501652.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Serra Mesa, San Diego ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Serra Mesa Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&lodging=APART_HOTEL) Resort [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&lodging=HOTEL_RESORT) Spa [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&amenities=SPA_ON_SITE) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&amenities=OCEAN_VIEW) Pool [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&lodging=APARTMENT) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&travelerType=family_friendly) Condo [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&lodging=CONDO) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&amenities=PETS) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&amenities=WATER_PARK) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&lodging=COTTAGE) ## Check prices for these dates Tonight [Oct 4 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-04&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Serra Mesa hotels and places to stay ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with digital channels, TV](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/d5ea2f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/5142b853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/88f9cd22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham San Diego Bayside 9.9 km from Serra Mesa 8.4/10 Very good (5958) "Great stay near the airport." CA $212 CA $287 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/60472bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/d85ecd0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/23e38216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hard Rock Hotel San Diego Gaslamp Quarter, 10.8 km from Serra Mesa 9.0/10 Wonderful (2974) "Loved staying here. Will definitely stay again " CA $250 CA $354 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/a314a493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/881441d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/63587042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Diego Gaslamp Quarter Gaslamp Quarter, 10.1 km from Serra Mesa 8.8/10 Excellent (1873) "would definitely stay again!" CA $157 CA $182 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2540b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/99024d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/a3c5905c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort 19.1 km from Serra Mesa 8.8/10 Excellent (1037) "Beautiful quiet hotel." CA $278 CA $372 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/a5cb77af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/8bb8fc35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/91baa1e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Marina Gateway Hotel 16.1 km from Serra Mesa 9.2/10 Wonderful (3299) "Great hotel" CA $180 CA $198 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/43298e98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/038c4b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/f7c3fa7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/289d71c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Suites by Wyndham San Diego/Hotel Circle Area 4.8 km from Serra Mesa 6.2/10 (1011) "comfortable, easy access, friendly staff" CA $106 CA $121 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/San-Diego-Hotels-Ramada-Suites-By-Wyndham-San-Diego.h11553.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/54935ba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/23c18b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/4d9ff339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/ddc5f050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gaslamp Plaza Suites Gaslamp Quarter, 10 km from Serra Mesa 8.8/10 Excellent (1007) "Had a great stay " CA $151 CA $171 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/San-Diego-Hotels-Gaslamp-Plaza-Suites.h16266.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/ce3fee83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/d9883b91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/c6debcd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/e3d5bf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Horton Grand, Downtown/Gaslamp Quarter 10.5 km from Serra Mesa 9.0/10 Wonderful (2584) "Great location and lovely staff. " CA $186 CA $253 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-The-Horton-Grand.h11026.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/75ec9582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/589f8e80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/f8b10da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sofia Hotel 10 km from Serra Mesa 8.4/10 Very good (1591) "Close to a lot of areas, would stay here again." CA $139 CA $195 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/4877ef6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/3a963240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/7bb755a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/1194fa32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cordova Hotel on Coronado Island 13.9 km from Serra Mesa 8.8/10 Excellent (1003) "We love this hotel. It gives a feel of having your own apartment on the island. The rooms is are clean and comfortable. The staff is welcoming and accommodating. The location is perfect. Close walking distance to the beach, dining, shopping, as well as the famous Del across the street. " CA $250 CA $317 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Coronado-Hotels-El-Cordova-Hotel-On-Coronado-Island.h11395.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/243b93bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/8f3ed06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/d154e491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/7f37543f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bristol Hotel San Diego 9.9 km from Serra Mesa 8.4/10 Very good (1385) "Very nice staff from check in, clean rooms, quiet and comfortable. " CA $186 CA $216 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/7442075b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/8077fd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa 5.7 km from Serra Mesa 9.2/10 Wonderful (2879) "Great stay overall" CA $250 CA $287 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/236157bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/e45ffdb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/dc860349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/8114cbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Pensione Hotel Little Italy, 9.3 km from Serra Mesa 8.6/10 Excellent (1865) "Great place to stay they are right in the middle of everything " CA $187 CA $213 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/San-Diego-Hotels-La-Pensione-Hotel.h914373.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3456147f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 2 Queen Beds, Accessible, Non Smoking (Mobility/Hearing Impaired)](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/30557300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Kitchenette](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/eff77449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego Hotel Circle 5.4 km from Serra Mesa 8.0/10 Very good (2345) "We loved our stay, great price, very clean and excellent location! " CA $137 CA $157 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![2 outdoor pools, a heated pool, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/01ecd568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/2c4c818b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/444d7583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Dana on Mission Bay 10.1 km from Serra Mesa 8.8/10 Excellent (3754) "Great stay! " CA $189 CA $245 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Premium bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/c31e05e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/89fdb8c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/ec632047.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/53d75480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staypineapple, Hotel Z, Gaslamp San Diego Gaslamp Quarter, 10.4 km from Serra Mesa 9.4/10 Exceptional (1001) "Great staff and clean rooms" CA $208 CA $281 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/San-Diego-Hotels-Staypineapple.h11486063.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/470000/460500/460447/0a2f5260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/470000/460500/460447/e3e7c4f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Bay View | View from room](https://images.trvl-media.com/lodging/1000000/470000/460500/460447/fd8eb6a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/470000/460500/460447/e8e82f93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Glorietta Bay Inn Coronado Island 13.9 km from Serra Mesa 8.6/10 Excellent (1001) "Great location" CA $276 CA $370 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Coronado-Hotels-Glorietta-Bay-Inn-Coronado-Island.h460447.Hotel-Information) ![Standard Room, 1 King Bed, Smoking](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/2b01136a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/e71b90b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/325ce31e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Smoking](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/1e9b6911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego-East/El Cajon 17.7 km from Serra Mesa 7.6/10 Good (1004) "Place was nice and comfy. Decent stay at a very genuine price. " CA $110 CA $121 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/El-Cajon-Hotels-Days-Inn-By-Wyndham-San-Diego-EastEl-Cajon.h1175963.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/d0638ef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/b8a10ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Queen Bed with Sofa bed](https://images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/73e1a4c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/ff1db9c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Boutique Hotel Little Italy, 9.3 km from Serra Mesa 8.6/10 Excellent (1246) "Great hotel and excellent location!" CA $136 CA $154 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/San-Diego-Hotels-Urban-Boutique-Hotel.h7341280.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/37cb1415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/1f20ac82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/676f55ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bay Club Hotel & Marina 12.6 km from Serra Mesa 9.0/10 Wonderful (2983) "Fantastic location, friendly staff great rooms" CA $187 CA $215 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-18&endDate=2025-10-19®ionId=553248635953501652&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Serra Mesa Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. - Downtown San Diego - Gaslamp Quarter - Pacific Beach - Mission Beach - Ocean Beach ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481093-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476416-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480743-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476415-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=800123) ![Downtown San Diego map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:yfwfEzeejUaMaj%40fa%40k%5CbLaPx%40qOkGcWu%40i%5B%60DgKrIcFdRgF%7CrAsAHjJvK%60IqKjOFzR%7EP%7CI%7BH%7CO%7CIfNma%40hn%40%7B%40fIe%5ChZma%40t%40o%40kSei%40E_FfEiEnLwEd%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cs9sAV_TcaQK48f0iT1-t86hPRE=) ### Downtown San Diego Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options. [See properties](https://www.expedia.ca/Hotel-Search?regionId=800123) ![Gaslamp Quarter showing street scenes, night scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22037-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/475000/475881-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480435-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480422-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480432-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6130021) ![Gaslamp Quarter map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mmtfEh%7CbjUAwJqIDCm%5B%60x%40OmEpJ%7DPD%40zAiE%40A_B%7BEBFj%5B_HH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=68cMX7ldk9-J6tcepLMBQKKwvpY=) ### Gaslamp Quarter Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6130021) ![Pacific Beach Park showing a sandy beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152283-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes rugged coastline, a coastal town and surfing](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152049-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a sandy beach and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152293-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152300-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes a beach bar and drinks or beverages](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152301-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6185751) ![Pacific Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:agfgEvyujUgHcNcG%60IiBwN%7BKtBkf%40inCoKyIyEoFcHy%40aKoT%60mBq_B%7Cl%40aZb%40xB%7DAlAuMdQsExHkAvMbB%7CVpV_F%7CGrk%40tPgDhDlTbMbDlZu%40%60V%7EDxQfMtAlJg%40xH_GxEkRnGkUrA%7DP%60IiFbTv%40lR%60J%7CNcKjBzCfUec%40%60L%7BUxIkP%60IuM%7CH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5FbBeekgWkepp0jnCE7WEy_Qh88=) ### Pacific Beach Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6185751) ![Belmont Park which includes a garden and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22160-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park featuring street scenes and rides as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22159-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park which includes a city, rides and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22161-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187064-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park ![Belmont Park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187072-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635998112279) ![Mission Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ec%7DfE%7CgujU_Die%40%7BAYqk%40sBclAvBeNh%40wNtAcg%40%60H_DqUxGwAlD%7EF%60Dm%40v%40%40Bb%40tDIhRqFnGs%40nEBzOdBzF%40xI%7DAvNwH%60BMfBZt%40m%40EhIzJy%40hNJI%7DIrBvAjErA%7EJb%40%7CMcEjJsFzArBfF%7EcA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hFrZWtAC8u-2IGYk_Bcs7ztzP5Q=) ### Mission Beach Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635998112279) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481019-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480252-San-Diego-City.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481012-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481011-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481016-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=177689) ![Ocean Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eq%7CfEneujUqO%7ByCl%5CdMdL%7B%40pnB%60%60BoUlb%40crB%60I&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=lCc_uj9JIfh1kP738Xl1bJJqo_A=) ### Ocean Beach Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego. [See properties](https://www.expedia.ca/Hotel-Search?regionId=177689) ## Top Serra Mesa Hotel Reviews ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Stay was excellent room always cleaned and beds made promptly. Room was very spacious and view of the bay with balcony amazing. Location is excellent." [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Pendry San Diego](//images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Hotel is pretty and is in a great location to be able to walk to shops, restaurants and bars " [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "It was centrally located,. I had private car and they had parking in. It was perfect for me, the rooms were comfortable and clean. Pretty view." [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Clean room" [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Thanks " [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![The Sofia Hotel](//images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Clean room, friendly staff " [](https://expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "We stayed for 9 nights and had an awesome time! Staff was friendly and accommodating. " [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Great ocean view located right on wide beach. Hotel is awesome." [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "The Manchester Grand Hyatt is our go to hotel in San Diego due to its convenient location by the Seaport Village and many restaurants and shops. We have stayed there several times and always enjoy the scenic views from our room and the hospitality of the hotel staff. The breakfast buffet has a large variety of offerings including an omelette station. The MarketOne Cafe downstairs has many items including delicious pastries and other food and drink items. It is always a great experience to stay at the Manchester Grand Hyatt in San Diego." [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ## Find out more about Serra Mesa ### Top reasons to visit Serra Mesa - **Outdoor Activities:** Serra Mesa offers a variety of outdoor adventures, including scenic drives, urban parks, and picnic areas, perfect for family outings. - **Nearby Beaches:** Just a short drive away, Mission Beach provides a stunning coastal experience for relaxation and fun in the sun. - **Cultural Experiences:** Engage with the local community through cultural activities and explore the area's rich history. - **Serra Mesa Recreation Center:** A hub for fun and leisure activities suitable for all ages. - **Family-Friendly Accommodations:** Enjoy a range of budget-friendly hotels and modern amenities catering to families and travellers alike. ### Find great hotels near Serra Mesa Discover a variety of hotel accommodations in Serra Mesa, San Diego, designed to suit every traveler's needs. Whether you seek adventure, a business-friendly environment, or a pet-friendly getaway, you'll find modern amenities and family-oriented options. Enjoy the charm of the Serra Mesa community with its inviting family homes, and make your stay memorable with convenient access to local attractions and the serene Murray Ridge Rd. - **[Wyndham San Diego Bayside:](https://www.expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information)** This 4-star hotel offers a business-friendly atmosphere with a touch of adventure, perfect for travellers seeking both productivity and recreational fun. Located 9.7km from Serra Mesa, it features extensive business amenities, including accessible meeting spaces and a dedicated business centre. Guests can indulge in various adventure sports nearby, such as kayaking, snorkeling, and sailing. The hotel is also pet-friendly, welcoming dogs and cats, with special amenities for service animals. Its unique blend of corporate facilities and outdoor activities makes it an excellent choice for both business and pleasure. - **[Days Inn by Wyndham San Diego Hotel Circle:](https://www.expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information)** A family-oriented 3-star hotel located 4.8km from Serra Mesa, Days Inn is known for its welcoming atmosphere, particularly for LGBTQIA travellers. This hotel provides a comfortable environment for families, offering amenities like free cribs for children. It also accommodates pets, allowing dogs with a waived fee for service animals. Guests appreciate the proximity to family-friendly attractions and the inclusive atmosphere, making it an ideal choice for those travelling with loved ones or looking for a welcoming getaway. - **[Best Western Seven Seas:](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)** Located 4.8km from Serra Mesa, this 3-star hotel caters to families and business travellers alike, offering a range of amenities to suit diverse needs. The hotel features accessible business facilities, including a business centre and meeting rooms, alongside recreational activities such as hiking and parasailing. Best Western Seven Seas is also family-friendly, providing cribs and ensuring a welcoming environment for children. Its combination of business amenities and family-oriented services ensures a comfortable and enjoyable stay for all guests. ### Where to stay near Serra Mesa Serra Mesa, a charming neighbourhood in San Diego, offers a delightful blend of outdoor adventures and family-friendly experiences. Explore the nearby Sorrento Mesa for its scenic parks and recreational areas, perfect for picnics and leisurely walks. The community is known for its welcoming atmosphere and budget-friendly options, making it an ideal base for excursions to nearby historical sites and attractions in Southern California. Enjoy the vibrant spirit of Serra Mesa and its surrounding areas during your visit. - **[San Diego:](https://www.expedia.ca/San-Diego-Hotels.d3073.Travel-Guide-Hotels)** As a vibrant city, San Diego is the heart of the region, with Serra Mesa nestled within its boundaries. Known for its beautiful beaches, outdoor activities, and family-friendly attractions, San Diego offers a year-round appeal. Visitors can explore iconic landmarks like theme parks and family beaches, making it perfect for family vacations. The city's diverse shopping centres and resorts add to its allure, ensuring a memorable travel experience filled with sun and fun. - **[Birdland:](https://www.expedia.ca/Birdland-San-Diego-Hotels.0-n553248635976479135-0.Travel-Guide-Filter-Hotels)** Just 1.6km from Serra Mesa, Birdland is a charming neighbourhood that invites outdoor enthusiasts and families alike. With its welcoming atmosphere, Birdland is a great spot for leisurely strolls along the bay and fun days at the beach. The area features diverse shopping options, including local malls and educational venues. Visitors flock here especially during the summer months, taking advantage of the warm weather while soaking in the scenic views and vibrant community vibe. - **[Mission Valley East:](https://www.expedia.ca/Mission-Valley-East-San-Diego-Hotels.0-n553248635976473513-0.Travel-Guide-Filter-Hotels)** Located 3.2km from Serra Mesa, Mission Valley East is a bustling neighbourhood that boasts a mix of family-friendly activities and business-themed experiences. This area is known for its shopping centres and malls, providing ample opportunities for retail therapy. With landmarks like sports facilities and stadiums nearby, it’s an excellent destination for sports enthusiasts. The vibrant streets and convenient access to city attractions make Mission Valley East a must-visit for those looking to explore San Diego’s dynamic urban life. ### Things to do near Serra Mesa Serra Mesa is an ideal spot for outdoor family vacations, offering a variety of activities and attractions. You can enjoy scenic drives and outdoor exploration, as well as relax at picnic areas. Nearby, Mission Beach provides a beautiful coastal experience, while shopping centres and malls cater to your retail needs. Whether you're seeking mountain adventures or a day at the beach, Serra Mesa has something for everyone. **Shopping** [Fashion Valley Mall](https://www.expedia.ca/Fashion-Valley-Mall-Hotels.0-l6168368-0.Travel-Guide-Filter-Hotels), located 4.8km from Serra Mesa, offers a vibrant shopping experience with entertainment and family-friendly options. Similarly, [Mission Valley Mall](https://www.expedia.ca/Mission-Valley-Mall-Hotels.0-l6168371-0.Travel-Guide-Filter-Hotels), just 3.2km away, provides a mix of business and leisure. Don't miss [Little Saigon](https://www.expedia.ca/Little-Saigon-Hotels.0-l717669176008921088-0.Travel-Guide-Filter-Hotels), 6.4km from Serra Mesa, for unique gifts and souvenirs. **Recreation** At [Riverwalk Golf Club](https://www.expedia.ca/Riverwalk-Golf-Club-Hotels.0-l6230056-0.Travel-Guide-Filter-Hotels), enjoy a round of golf amidst beautiful landscapes, perfect for relaxation and outdoor fun. Nearby, [Petco Park](https://www.expedia.ca/Petco-Park-Hotels.0-l6034816-0.Travel-Guide-Filter-Hotels) offers thrilling sports experiences, while [The Rady Shell at Jacobs Park](https://www.expedia.ca/The-Rady-Shell-At-Jacobs-Park-Hotels.0-l786334869552062464-0.Travel-Guide-Filter-Hotels) provides vibrant musical performances, blending entertainment with a lively atmosphere just a short drive away. **Adventure** At the Aztec Tennis Center, located 6.4km from Serra Mesa, you can enjoy thrilling matches surrounded by vibrant energy. The Barnes Tennis Center, 11.3km away, offers a lively atmosphere for passionate players. Experience a dynamic setting at the Urban Village Tennis Center, also 6.4km from Serra Mesa. **Nightlife** In Serra Mesa, the vibrant nightlife includes the [San Diego Civic Theatre](https://www.expedia.ca/San-Diego-Civic-Theatre-Hotels.0-l553248621555611975-0.Travel-Guide-Filter-Hotels), showcasing engaging performances just 9.7km away, and the charming [Balboa Park Carousel](https://www.expedia.ca/Balboa-Park-Carousel-Hotels.0-l6230108-0.Travel-Guide-Filter-Hotels), offering delightful outdoor fun 8.0km away. For adventure seekers, [Boomers San Diego](https://www.expedia.ca/Boomers-San-Diego-Hotels.0-l553248621555611938-0.Travel-Guide-Filter-Hotels) is an exciting arcade experience located 4.8km away. *\*Distances are measured in a straight line; actual driving distances may vary depending on the route.* ### Booking tips and Expedia advantages for Serra Mesa To save money on your trip to Serra Mesa, consider visiting from November to January when accommodation prices are lower, especially on Tuesdays. Avoid Saturdays for your stay as they tend to be pricier. Use Expedia's search tool to filter for budget-friendly options, including Eco-certified hotels. You can also save by bundling your hotel, flights, and activities through Expedia packages. Additionally, explore free activities in the area to enhance your experience without breaking the bank. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Serra Mesa are November to January, where the prices are slightly lower. This is in comparison to June to August, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Serra Mesa is Tuesday. The most expensive day to stay around Serra Mesa is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and type of accommodation. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels currently available. To find the best prices and offers, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save some dollars by combining your Serra Mesa hotel reservation with your flights and activities through an Expedia package. ### Find the best attractions near Serra Mesa Serra Mesa is perfect for outdoor family vacations, offering various attractions like modern colleges, urban parks, and private gardens. Visitors can enjoy cultural experiences and outdoor activities, making it an ideal destination for families. Don't miss the Serra Mesa Recreation Center, which provides additional opportunities for fun and leisure. With its blend of nature and community, Serra Mesa promises a delightful getaway for tourists seeking both relaxation and adventure. - **[Mission Bay:](https://www.expedia.ca/Mission-Bay-Hotels.0-l6185904-0.Travel-Guide-Filter-Hotels)** Located 8.0km from Serra Mesa, Mission Bay offers a stunning waterfront experience with sandy beaches, lush parks, and breathtaking sunsets. It's perfect for outdoor activities like kayaking, paddleboarding, or simply relaxing by the shore. - **[Balboa Park:](https://www.expedia.ca/Balboa-Park-Hotels.0-l507458-0.Travel-Guide-Filter-Hotels)** Also 8.0km away, Balboa Park is a sprawling urban oasis featuring beautiful gardens, walking paths, and world-class museums. This cultural hub is ideal for leisurely strolls and enjoying art and nature. - **[Hotel Circle:](https://www.expedia.ca/Hotel-Circle-Hotels.0-l6270979-0.Travel-Guide-Filter-Hotels)** Just 4.8km from Serra Mesa, Hotel Circle is a bustling street lined with various hotels, dining options, and entertainment venues, giving you a taste of San Diego's vibrant city life. ### Best time to go to Serra Mesa The best time to visit Serra Mesa is dependant on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are average and weather is sunny with no rain. February is its coolest month on average. At this time, visitor numbers are average and weather is sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 57.4°F (14.1°C) | Light Rain | Sunny | Moderately Low | Slightly Low | | February | 56.8°F (13.8°C) | Light Rain | Sunny | Average | Average | | March | 58.1°F (14.5°C) | No Rain | Mostly Sunny | Moderately High | Average | | April | 60.6°F (15.9°C) | No Rain | Sunny | Average | Average | | May | 62.6°F (17.0°C) | No Rain | Sunny | Average | Average | | June | 66.4°F (19.1°C) | No Rain | Sunny | Moderately High | Slightly High | | July | 70.5°F (21.4°C) | No Rain | Sunny | Moderately High | Slightly High | | August | 72.3°F (22.4°C) | No Rain | Sunny | Average | Slightly High | | September | 72.0°F (22.2°C) | No Rain | Sunny | Average | Average | | October | 68.2°F (20.1°C) | No Rain | Sunny | Moderately Low | Average | | November | 62.6°F (17.0°C) | No Rain | Sunny | Moderately Low | Slightly Low | | December | 57.4°F (14.1°C) | Light Rain | Mostly Sunny | Average | Slightly Low | ### The nearest major airports for your trip to Serra Mesa When visiting Serra Mesa in San Diego, California, the primary airport options are San Diego International Airport ([SAN](https://www.expedia.ca/San-Diego-Intl-Airport-Hotels.0-aSAN-0.Travel-Guide-Filter-Hotels)) and Tijuana's General Abelardo L. Rodriguez International Airport ([TIJ](https://www.expedia.ca/General-Abelardo-L-Rodriguez-Intl-Airport-Hotels.0-aTIJ-0.Travel-Guide-Filter-Hotels)). SAN is situated 9.7km away, with nearby hotels like the 5-star [Pendry San Diego](https://www.expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) and [The US Grant](https://www.expedia.ca/San-Diego-Hotels-THE-US-GRANT.h10802.Hotel-Information), both within 4.8km. Montgomery Field ([MYF](https://www.expedia.ca/Montgomery-Field-Airport-Hotels.0-aMYF-0.Travel-Guide-Filter-Hotels)) is only 0.9.7km from Serra Mesa, and the [Fairmont Grand Del Mar](https://www.expedia.ca/San-Diego-Hotels-Fairmont-Grand-Del-Mar.h1779742.Hotel-Information) is a notable 5-star option 14.5km away. For those considering TIJ, it is 32.2km from Serra Mesa, with excellent accommodations like the 4.5-star [Quartz Hotel & SPA](https://www.expedia.ca/Tijuana-Hotels-Quartz-Hotel-SPA.h36996325.Hotel-Information), also 4.8km from the airport. ## Frequently asked questions ### What are the best hotels in Serra Mesa that travellers recommend? > [Springhill Suites San Diego Mission Valley](https://www.expedia.ca/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) stands out as an exceptional choice for travellers, earning an excellent review score of 9.0. This hotel offers spacious suites that provide a comfortable base for your adventures in San Diego. Guests rave about the complimentary breakfast options, which are superb for fueling up before a day of adventure. The outdoor pool and fitness facilities cater to both relaxation and active pursuits, making it an ideal stay for couples and families alike. > > > > Families will find the [TownePlace Suites by Marriott San Diego Central](https://www.expedia.ca/San-Diego-Hotels-TownePlace-Suites-By-Marriott-San-Diego-Central.h30450040.Hotel-Information) to be a particularly appealing option, also rated at 9.0. With amenities like a fully-equipped kitchen and an outdoor pool, this hotel makes it easy to enjoy a home-away-from-home experience. The buffet breakfast is a hit among parents and kids, ensuring everyone starts their day on a tasty note. Plus, the nearby rock climbing and mountain biking opportunities add a dash of adventure for the more active families. > > > > For those seeking a vibrant atmosphere, [Town and Country San Diego](https://www.expedia.ca/San-Diego-Hotels-Town-And-Country-San-Diego.h21394.Hotel-Information) offers an engaging experience with a review score of 8.6. This family-friendly resort features a heated pool with a waterslide and playground, making it a fantastic option for those traveling with children. The proximity to local attractions and shopping ensures that both parents and kids will have plenty to do during their stay. > > > > Business travellers will appreciate the [Courtyard by Marriott San Diego Central](https://www.expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Central.h854424.Hotel-Information), which also holds an 8.6 rating. With a focus on convenience, this hotel offers early check-in options, a business centre, and fitness facilities that cater to professionals on the go. The outdoor pool area provides a refreshing way to unwind after a busy day of meetings, ensuring a balanced stay. > > > > Lastly, for those looking for a blend of comfort and accessibility, the [San Diego Marriott Mission Valley](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Mission-Valley.h8332.Hotel-Information), rated 8.6, provides a welcoming environment. With features such as a rooftop garden and modern meeting facilities, it's well-suited for both leisure and business travellers. The poolside cabanas invite relaxation, while the nearby attractions make it easy to explore the best of San Diego. ### What are the best family hotels in Serra Mesa? > For families seeking a welcoming stay in Serra Mesa, the [Springhill Suites San Diego Mission Valley](https://www.expedia.ca/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) stands out with its excellent amenities tailored for parents and children alike. With a spacious pool area where the kids can splash around, this hotel also offers connecting rooms and cribs for your little ones, ensuring comfort and convenience during your stay. Guests rave about the complimentary breakfast available on weekdays, a great way to fuel up for a day of adventure. > > > > Another fantastic option is the [TownePlace Suites by Marriott San Diego Central](https://www.expedia.ca/San-Diego-Hotels-TownePlace-Suites-By-Marriott-San-Diego-Central.h30450040.Hotel-Information), which boasts similar family-friendly amenities such as connecting rooms and a refreshing pool. The hotel goes the extra mile by providing free meals for children, making dining easier for families. Plus, with amenities like microwaves and dishwashers in the rooms, preparing snacks or meals becomes a breeze. > > > > For a more playful experience, the [Town and Country San Diego](https://www.expedia.ca/San-Diego-Hotels-Town-And-Country-San-Diego.h21394.Hotel-Information) is an ideal choice. This vibrant hotel not only has multiple pools for cooling off but also features a playground and fun games designed especially for children. It even offers a waterslide, making it a hit with the younger guests. With connecting rooms and kids' meals available, it's a family paradise. > > > > Lastly, the [San Diego Marriott Mission Valley](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Mission-Valley.h8332.Hotel-Information) is another excellent family-friendly hotel. It provides connecting rooms and a peaceful garden area, superb for some outdoor family time. With its proximity to nearby theme parks, this hotel adds an adventurous touch to your stay, ensuring that the whole family enjoys their vacation. > > > > Each of these hotels has received positive reviews, making them reliable choices for families looking to balance comfort, adventure, and great value on their trip. ### What are the best spa hotels in Serra Mesa? > For a rejuvenating retreat in Serra Mesa, the [WorldMark San Diego - Mission Valley](https://www.expedia.ca/San-Diego-Hotels-WorldMark-San-Diego-Mission-Valley.h40963.Hotel-Information) is a great choice, receiving a rating of 8.6 from guests. This hotel features accessible spa facilities that make relaxation easy and enjoyable for everyone. With a inviting space and comfortable accommodations, it's an ideal spot for travellers looking to unwind after a day of adventure. > > > > Another option is the [Best Western Seven Seas](https://www.expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information), which offers accessible spa amenities as well, rated at 7.8. This hotel combines convenience and comfort, ensuring guests have a pleasant stay while enjoying the soothing spa services available. ### What hotels in Serra Mesa offer free breakfast? > [Springhill Suites San Diego Mission Valley](https://www.expedia.ca/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) is a fantastic choice for travellers seeking comfort and convenience, especially families. This hotel offers a delightful free continental breakfast, ensuring everyone starts their day off right. With a spacious outdoor pool, it provides a great retreat for kids to splash around while parents unwind. The hotel also features accessible parking and pet-friendly options, suiting a wide range of guests. > > > > Another excellent option is [TownePlace Suites by Marriott San Diego Central](https://www.expedia.ca/San-Diego-Hotels-TownePlace-Suites-By-Marriott-San-Diego-Central.h30450040.Hotel-Information). Here, you can enjoy a complimentary buffet breakfast that will fuel your family's adventures. The outdoor pool is secure and surrounded by sun loungers, making it an inviting space for relaxation. Additionally, the property includes fully-equipped kitchenettes, great for families who prefer to prepare their own meals. > > > > For those traveling without children, the [Homewood Suites by Hilton San Diego Mission Valley/Zoo](https://www.expedia.ca/San-Diego-Hotels-Homewood-Suites-By-Hilton-San-Diego-Mission-ValleyZoo.h13086924.Hotel-Information) offers a more tranquil experience with its premium rooms and a lovely outdoor pool. Couples can enjoy the proximity to local attractions, while still relishing the comforts of home with the in-suite kitchenettes. > > > > Whether you're traveling with family or as a couple, these properties in Serra Mesa provide an array of amenities designed to enhance your stay while ensuring good value for your investment. ### What are the best budget hotels in Serra Mesa? > If you're looking for budget-friendly accommodations in Serra Mesa, the [Springhill Suites San Diego Mission Valley](https://www.expedia.ca/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) stands out as a fantastic option. With a guest review rating of 9.0, this hotel features spacious suites that are great for families seeking a comfortable stay. Enjoy a refreshing dip in the outdoor pool or start your day with a complimentary continental breakfast, which is available on weekends too. Families will appreciate the free cribs and the convenient in-room WiFi, making it easy to stay connected while on vacation. > > > > Another excellent choice is the [TownePlace Suites by Marriott San Diego Central](https://www.expedia.ca/San-Diego-Hotels-TownePlace-Suites-By-Marriott-San-Diego-Central.h30450040.Hotel-Information), also rated 9.0 by travellers. This hotel has a inviting space with ample amenities, including an outdoor pool, kitchen facilities for easy meal prep, and a grocery shopping service. The complimentary breakfast ensures everyone gets a good start to their day before heading off for family adventures. > > > > For those traveling with children, the [Homewood Suites by Hilton San Diego Mission Valley/Zoo](https://www.expedia.ca/San-Diego-Hotels-Homewood-Suites-By-Hilton-San-Diego-Mission-ValleyZoo.h13086924.Hotel-Information), with a rating of 8.4, is another family-friendly option. This hotel features a kitchenette, making it ideal for families who prefer the convenience of preparing their own meals. Plus, the outdoor pool provides a great spot for kids to splash around after a day of exploring the nearby attractions. > > > > If you're traveling as a couple or looking for a more romantic getaway, consider the [Courtyard by Marriott San Diego Central](https://www.expedia.ca/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Central.h854424.Hotel-Information). With a rating of 8.6, this hotel boasts a serene atmosphere, a hot tub for relaxation, and easy access to local attractions, great for couples seeking a blend of comfort and convenience. > > > > In summary, whether you're traveling with kids or looking for a peaceful retreat, Serra Mesa offers budget-friendly options that cater to a variety of needs and preferences. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Serra Mesa hotel for you. ### How can I save on a Serra Mesa hotel booking with Expedia? > With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Serra Mesa hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings. ### How much is the nightly rate at a Serra Mesa hotel? > Hotel prices in Serra Mesa often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels near Adams Avenue Park](https://www.expedia.ca/Adams-Avenue-Park-Hotels.0-l553248621558033903-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Birdland](https://www.expedia.ca/Birdland-San-Diego-Hotels-Cheap-Hotels.0-n553248635976479135-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Birdland Hotels](https://www.expedia.ca/Birdland-San-Diego-Hotels.0-n553248635976479135-0.Travel-Guide-Filter-Hotels) - [Central San Diego Hotels](https://www.expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels) - [Clairemont Mesa East Hotels](https://www.expedia.ca/Clairemont-Mesa-East-San-Diego-Hotels.0-n553248635976471258-0.Travel-Guide-Filter-Hotels) - [Clairemont Mesa Hotels](https://www.expedia.ca/Clairemont-Mesa-San-Diego-Hotels.0-n553248635976469557-0.Travel-Guide-Filter-Hotels) - [Clairemont Hotels](https://www.expedia.ca/Clairemont-San-Diego-Hotels.0-n177692-0.Travel-Guide-Filter-Hotels) - [Hotels near Convoy District](https://www.expedia.ca/Convoy-District-Hotels.0-l797585748502450176-0.Travel-Guide-Filter-Hotels) - [San Diego County Hotels](https://www.expedia.ca/Destinations-In-San-Diego-County.d178304.Hotel-Destinations) - [Hotels near Fashion Valley Mall](https://www.expedia.ca/Fashion-Valley-Mall-Hotels.0-l6168368-0.Travel-Guide-Filter-Hotels) - [Grantville Hotels](https://www.expedia.ca/Grantville-San-Diego-Hotels.0-n553248635976474065-0.Travel-Guide-Filter-Hotels) - [Hotels near Hazard Center Station](https://www.expedia.ca/Hazard-Center-Station-Hotels.d6187043.Travel-Guide-Hotels) - [Hotels near Hotel Circle](https://www.expedia.ca/Hotel-Circle-Hotels.0-l6270979-0.Travel-Guide-Filter-Hotels) - [Kearny Mesa Hotels](https://www.expedia.ca/Kearny-Mesa-San-Diego-Hotels.0-n3000663380-0.Travel-Guide-Filter-Hotels) - [Kensington Hotels](https://www.expedia.ca/Kensington-San-Diego-Hotels.0-n553248635976008172-0.Travel-Guide-Filter-Hotels) - [Linda Vista Hotels](https://www.expedia.ca/Linda-Vista-San-Diego-Hotels.0-n553248635976388645-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission Basilica San Diego de Alcala](https://www.expedia.ca/Mission-Basilica-San-Diego-De-Alcala-Hotels.0-l6128001-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission San Diego Station](https://www.expedia.ca/Mission-San-Diego-Station-Hotels.d6187070.Travel-Guide-Hotels) - [Extended Stay America Hotels in Mission Valley East](https://www.expedia.ca/Mission-Valley-East-San-Diego-Hotels-Extended-Stay-America.0-n553248635976473513-0--bExtendedStayAmerica.Travel-Guide-Filter-Hotels) - [Mission Valley East Hotels](https://www.expedia.ca/Mission-Valley-East-San-Diego-Hotels.0-n553248635976473513-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission Valley Mall](https://www.expedia.ca/Mission-Valley-Mall-Hotels.0-l6168371-0.Travel-Guide-Filter-Hotels) - [Mission Valley Hotels](https://www.expedia.ca/Mission-Valley-San-Diego-Hotels.0-n800124-0.Travel-Guide-Filter-Hotels) - [Mission Valley West Hotels](https://www.expedia.ca/Mission-Valley-West-San-Diego-Hotels.0-n553248635976480019-0.Travel-Guide-Filter-Hotels) - [Hotels near Montgomery Field](https://www.expedia.ca/Montgomery-Field-Airport-Hotels.0-aMYF-0.Travel-Guide-Filter-Hotels) - [Normal Heights Hotels](https://www.expedia.ca/Normal-Heights-San-Diego-Hotels.0-n553248635976007226-0.Travel-Guide-Filter-Hotels) - [Hotels near Qualcomm Stadium Station](https://www.expedia.ca/Qualcomm-Stadium-Station-Hotels.d6187065.Travel-Guide-Hotels) - [Hotels near Rio Vista Station](https://www.expedia.ca/Rio-Vista-Station-Hotels.d6187053.Travel-Guide-Hotels) - [Hotels near Riverwalk Golf Club](https://www.expedia.ca/Riverwalk-Golf-Club-Hotels.0-l6230056-0.Travel-Guide-Filter-Hotels) - [San Diego Hotels](https://www.expedia.ca/San-Diego-Hotels.d3073.Travel-Guide-Hotels) - [Hotels near Snapdragon Stadium](https://www.expedia.ca/Snapdragon-Stadium-Hotels.0-l502539-0.Travel-Guide-Filter-Hotels) - [Tierrasanta Hotels](https://www.expedia.ca/Tierrasanta-San-Diego-Hotels.0-n553248635976007565-0.Travel-Guide-Filter-Hotels) - [University Heights Hotels](https://www.expedia.ca/University-Heights-San-Diego-Hotels.0-n553248635976007534-0.Travel-Guide-Filter-Hotels) - [Flights to San Diego](https://www.expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights) - [Flights from Montgomery Field](https://www.expedia.ca/lp/airports/myf/flights-from-montgomery-field-airport) - [Hopscotch Air Olympia (OLM) to San Diego (MYF) flights](https://www.expedia.ca/lp/flight-routes/hopscotch-air-from-olympia-regional-to-montgomery-field/o2/olm/myf) - [Flights from Alice (ALI) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ali/myf/alice-to-san-diego) - [Flights from Amsterdam (AMS) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ams/myf/amsterdam-to-san-diego) - [Flights from Bakersfield (BFL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bfl/myf/bakersfield-to-san-diego) - [Flights from Bishop (BIH) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bih/myf/bishop-to-san-diego) - [Flights from Bellingham (BLI) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bli/myf/bellingham-to-san-diego) - [Flights from Boston (BOS) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bos/myf/boston-to-san-diego) - [Flights from Burlington (BTV) to San Diego (MYF)](https://www.expedia.ca/lp/flights/btv/myf/burlington-to-san-diego) - [Flights from Borrego Springs (BXS) to San Diego (MYF)](https://www.expedia.ca/lp/flights/bxs/myf/borrego-springs-to-san-diego) - [Flights from Upland (CCB) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ccb/myf/upland-to-san-diego) - [Flights from College Park (CGS) to San Diego (MYF)](https://www.expedia.ca/lp/flights/cgs/myf/college-park-to-san-diego) - [Flights from Clovis (CVN) to San Diego (MYF)](https://www.expedia.ca/lp/flights/cvn/myf/clovis-to-san-diego) - [Flights from Corvallis (CVO) to San Diego (MYF)](https://www.expedia.ca/lp/flights/cvo/myf/corvallis-to-san-diego) - [Flights from Calexico (CXL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/cxl/myf/calexico-to-san-diego) - [Flights from Barstow (DAG) to San Diego (MYF)](https://www.expedia.ca/lp/flights/dag/myf/barstow-to-san-diego) - [Flights from Detroit (DTT) to San Diego (MYF)](https://www.expedia.ca/lp/flights/dtt/myf/detroit-to-san-diego) - [Flights from Detroit (DTW) to San Diego (MYF)](https://www.expedia.ca/lp/flights/dtw/myf/detroit-to-san-diego) - [Flights from Douglas (DUG) to San Diego (MYF)](https://www.expedia.ca/lp/flights/dug/myf/douglas-to-san-diego) - [Flights from Newark Liberty Intl. Airport (EWR) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ewr/myf/newark-liberty-intl-airport-to-san-diego) - [Flights from Fallon (FLX) to San Diego (MYF)](https://www.expedia.ca/lp/flights/flx/myf/fallon-to-san-diego) - [Flights from Sioux Falls (FSD) to San Diego (MYF)](https://www.expedia.ca/lp/flights/fsd/myf/sioux-falls-to-san-diego) - [Flights from Gallup (GUP) to San Diego (MYF)](https://www.expedia.ca/lp/flights/gup/myf/gallup-to-san-diego) - [Flights from Hawthorne (HHR) to San Diego (MYF)](https://www.expedia.ca/lp/flights/hhr/myf/hawthorne-to-san-diego) - [Flights from Hot Springs (HOT) to San Diego (MYF)](https://www.expedia.ca/lp/flights/hot/myf/hot-springs-to-san-diego) - [Flights from Henderson (HSH) to San Diego (MYF)](https://www.expedia.ca/lp/flights/hsh/myf/henderson-to-san-diego) - [Flights from Hayward (HWD) to San Diego (MYF)](https://www.expedia.ca/lp/flights/hwd/myf/hayward-to-san-diego) - [Flights from Indianapolis (IND) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ind/myf/indianapolis-to-san-diego) - [Flights from International Falls (INL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/inl/myf/international-falls-to-san-diego) - [Flights from El Centro (IPL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ipl/myf/el-centro-to-san-diego) - [Flights from New York (JFK) to San Diego (MYF)](https://www.expedia.ca/lp/flights/jfk/myf/new-york-to-san-diego) - [Flights from Los Angeles (LAX) to San Diego (MYF)](https://www.expedia.ca/lp/flights/lax/myf/los-angeles-to-san-diego) - [Flights from Harrisburg (MDT) to San Diego (MYF)](https://www.expedia.ca/lp/flights/mdt/myf/harrisburg-to-san-diego) - [Flights from Mexico City (MEX) to San Diego (MYF)](https://www.expedia.ca/lp/flights/mex/myf/mexico-city-to-san-diego) - [Flights from Milan (MIL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/mil/myf/milan-to-san-diego) - [Flights from Mammoth Lakes (MMH) to San Diego (MYF)](https://www.expedia.ca/lp/flights/mmh/myf/mammoth-lakes-to-san-diego) - [Flights from Modesto (MOD) to San Diego (MYF)](https://www.expedia.ca/lp/flights/mod/myf/modesto-to-san-diego) - [Flights from Oaxaca Intl. (OAX) to San Diego (MYF)](https://www.expedia.ca/lp/flights/oax/myf/oaxaca-intl-to-san-diego) - [Flights from Oceanside (OCN) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ocn/myf/oceanside-to-san-diego) - [Flights from Nogales (OLS) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ols/myf/nogales-to-san-diego) - [Flights from Omaha (OMA) to San Diego (MYF)](https://www.expedia.ca/lp/flights/oma/myf/omaha-to-san-diego) - [Flights from Phoenix (PHX) to San Diego (MYF)](https://www.expedia.ca/lp/flights/phx/myf/phoenix-to-san-diego) - [Flights from Pompano Beach (PPM) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ppm/myf/pompano-beach-to-san-diego) - [Flights from Murrieta (RBK) to San Diego (MYF)](https://www.expedia.ca/lp/flights/rbk/myf/murrieta-to-san-diego) - [Flights from Redding (RDD) to San Diego (MYF)](https://www.expedia.ca/lp/flights/rdd/myf/redding-to-san-diego) - [Flights from Rifle (RIL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ril/myf/rifle-to-san-diego) - [Flights from Mariposa (RMY) to San Diego (MYF)](https://www.expedia.ca/lp/flights/rmy/myf/mariposa-to-san-diego) - [Flights from Reno (RNO) to San Diego (MYF)](https://www.expedia.ca/lp/flights/rno/myf/reno-to-san-diego) - [Flights from Seattle (SEA) to San Diego (MYF)](https://www.expedia.ca/lp/flights/sea/myf/seattle-to-san-diego) - [Flights from San Francisco (SFO) to San Diego (MYF)](https://www.expedia.ca/lp/flights/sfo/myf/san-francisco-to-san-diego) - [Flights from Spearfish (SPF) to San Diego (MYF)](https://www.expedia.ca/lp/flights/spf/myf/spearfish-to-san-diego) - [Flights from San Carlos (SQL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/sql/myf/san-carlos-to-san-diego) - [Flights from Santa Paula (SZP) to San Diego (MYF)](https://www.expedia.ca/lp/flights/szp/myf/santa-paula-to-san-diego) - [Flights from Tacoma (TIW) to San Diego (MYF)](https://www.expedia.ca/lp/flights/tiw/myf/tacoma-to-san-diego) - [Flights from Temple (TPL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/tpl/myf/temple-to-san-diego) - [Flights from Watsonville (WVI) to San Diego (MYF)](https://www.expedia.ca/lp/flights/wvi/myf/watsonville-to-san-diego) - [Flights from Ottawa (YOW) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yow/myf/ottawa-to-san-diego) - [Flights from Montreal (YUL) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yul/myf/montreal-to-san-diego) - [Flights from Yuma (YUM) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yum/myf/yuma-to-san-diego) - [Flights from Vancouver (YVR) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yvr/myf/vancouver-to-san-diego) - [Flights from Vancouver (YVR) to San Diego (SAN)](https://www.expedia.ca/lp/flights/yvr/san/vancouver-to-san-diego) - [Flights from Winnipeg (YWG) to San Diego (MYF)](https://www.expedia.ca/lp/flights/ywg/myf/winnipeg-to-san-diego) - [Flights from Calgary (YYC) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yyc/myf/calgary-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (MYF)](https://www.expedia.ca/lp/flights/yyz/myf/toronto-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (SAN)](https://www.expedia.ca/lp/flights/yyz/san/toronto-to-san-diego) - [Visit Birdland](https://www.expedia.ca/San-Diego-Birdland.dx553248635976479135) - [Rental cars San Diego Intl. airport](https://www.expedia.ca/Car-Rentals-In-San-Diego-Intl.d5128531.Car-Rental-Guide) - [Book Hotels in Serra Mesa on Expedia.com](https://www.expedia.com/Serra-Mesa-San-Diego-Hotels.0-n553248635953501652-0.Travel-Guide-Filter-Hotels) - Explore a world of travel with Expedia ### Hotels in top San Diego neighborhoods - [Hotels in Downtown San Diego](https://expedia.ca/Downtown-San-Diego-San-Diego-Hotels.0-n800123-0.Travel-Guide-Filter-Hotels) - [Hotels in Gaslamp Quarter](https://expedia.ca/Gaslamp-Quarter-San-Diego-Hotels.0-n6130021-0.Travel-Guide-Filter-Hotels) - [Hotels in Pacific Beach](https://expedia.ca/Pacific-Beach-San-Diego-Hotels.0-n6185751-0.Travel-Guide-Filter-Hotels) - [Hotels in Mission Beach](https://expedia.ca/Mission-Beach-San-Diego-Hotels.0-n553248635998112279-0.Travel-Guide-Filter-Hotels) - [Hotels in Ocean Beach](https://expedia.ca/Ocean-Beach-San-Diego-Hotels.0-n177689-0.Travel-Guide-Filter-Hotels) - [Hotels in Point Loma](https://expedia.ca/Point-Loma-San-Diego-Hotels.0-n6171538-0.Travel-Guide-Filter-Hotels) - [Hotels in Mission Valley](https://expedia.ca/Mission-Valley-San-Diego-Hotels.0-n800124-0.Travel-Guide-Filter-Hotels) - [Hotels in Central Mission Beach](https://expedia.ca/Central-Mission-Beach-San-Diego-Hotels.0-n553248635975748394-0.Travel-Guide-Filter-Hotels) - [Hotels in Old Town San Diego](https://expedia.ca/Old-Town-San-Diego-San-Diego-Hotels.0-n6347116-0.Travel-Guide-Filter-Hotels) - [Hotels in Little Italy](https://expedia.ca/Little-Italy-San-Diego-Hotels.0-n6161280-0.Travel-Guide-Filter-Hotels) - [Hotels in North Pacific Beach](https://expedia.ca/North-Pacific-Beach-San-Diego-Hotels.0-n553248635976383450-0.Travel-Guide-Filter-Hotels) - [Hotels in Crown Point](https://expedia.ca/Crown-Point-San-Diego-Hotels.0-n553248635976468673-0.Travel-Guide-Filter-Hotels) - [Hotels in South Mission Beach](https://expedia.ca/South-Mission-Beach-San-Diego-Hotels.0-n553248635975748186-0.Travel-Guide-Filter-Hotels) - [Hotels in North Park](https://expedia.ca/North-Park-San-Diego-Hotels.0-n6346499-0.Travel-Guide-Filter-Hotels) - [Hotels in Carmel Valley](https://expedia.ca/Carmel-Valley-San-Diego-Hotels.0-n553248633938969513-0.Travel-Guide-Filter-Hotels) - [Hotels in East Village](https://expedia.ca/East-Village-San-Diego-Hotels.0-n553248633849130034-0.Travel-Guide-Filter-Hotels) - [Hotels in Hillcrest](https://expedia.ca/Hillcrest-San-Diego-Hotels.0-n6191797-0.Travel-Guide-Filter-Hotels) - [Hotels in University City](https://expedia.ca/University-City-San-Diego-Hotels.0-n553248635976008131-0.Travel-Guide-Filter-Hotels) - [Hotels in Point Loma Heights](https://expedia.ca/Point-Loma-Heights-San-Diego-Hotels.0-n553248632557191746-0.Travel-Guide-Filter-Hotels) - [Hotels in Del Cerro](https://expedia.ca/Del-Cerro-San-Diego-Hotels.0-n553248635976469597-0.Travel-Guide-Filter-Hotels) ### Hotels near popular San Diego Attractions - [Hotels near Stadium Golf Center & Batting Cages](https://expedia.ca/Stadium-Golf-Center-Batting-Cages-Hotels.0-l553248621555611799-0.Travel-Guide-Filter-Hotels) - [Hotels near San Diego Zoo](https://expedia.ca/San-Diego-Zoo-Hotels.0-l502547-0.Travel-Guide-Filter-Hotels) - [Hotels near San Diego Convention Center](https://expedia.ca/San-Diego-Convention-Center-Hotels.0-l6125294-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission Bay](https://expedia.ca/Mission-Bay-Hotels.0-l6185904-0.Travel-Guide-Filter-Hotels) - [Hotels near San Ysidro Border Crossing](https://expedia.ca/San-Ysidro-Border-Crossing-Hotels.0-l553248621551385128-0.Travel-Guide-Filter-Hotels) - [Hotels near Petco Park](https://expedia.ca/Petco-Park-Hotels.0-l6034816-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission Beach](https://expedia.ca/Mission-Beach-Hotels.0-l506109-0.Travel-Guide-Filter-Hotels) - [Hotels near Balboa Park](https://expedia.ca/Balboa-Park-Hotels.0-l507458-0.Travel-Guide-Filter-Hotels) - [Hotels near San Diego State University](https://expedia.ca/San-Diego-State-University-Hotels.0-l502542-0.Travel-Guide-Filter-Hotels) - [Hotels near Hotel Circle](https://expedia.ca/Hotel-Circle-Hotels.0-l6270979-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Serra Mesa - [Vacation Homes in San Diego](https://expedia.ca/San-Diego-Private-Vacation-Homes.d3073-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in San Diego](https://expedia.ca/San-Diego-Apartments.d3073-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in San Diego](https://expedia.ca/San-Diego-Condos.d3073-aaCondos.Travel-Guide-Accommodation) - [Cottages in San Diego](https://expedia.ca/San-Diego-Cottages.d3073-aaCottages.Travel-Guide-Accommodation) - [Villas in San Diego](https://expedia.ca/San-Diego-Villas.d3073-aaVillas.Travel-Guide-Accommodation) - [Guest Houses in San Diego](https://expedia.ca/San-Diego-Guest-Houses.d3073-aaGuestHouses.Travel-Guide-Accommodation) - [Aparthotels in San Diego](https://expedia.ca/San-Diego-Apart-Hotels.d3073-aaApartHotels.Travel-Guide-Accommodation) - [Resorts in San Diego](https://expedia.ca/San-Diego-Resort-Hotels.d3073-aaResortHotels.Travel-Guide-Accommodation) - [Motels in San Diego](https://expedia.ca/San-Diego-Motels.d3073-aaMotels.Travel-Guide-Accommodation) - [Hostels in San Diego](https://expedia.ca/San-Diego-Hostels.d3073-aaHostels.Travel-Guide-Accommodation) - [B&B in San Diego](https://expedia.ca/San-Diego-Bed-And-Breakfast.d3073-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Houseboats in San Diego](https://expedia.ca/San-Diego-Houseboats.d3073-aaHouseboats.Travel-Guide-Accommodation) - [Inns in San Diego](https://expedia.ca/San-Diego-Inns.d3073-aaInns.Travel-Guide-Accommodation) - [Farmstay in San Diego](https://expedia.ca/San-Diego-Agritourism.d3073-aaAgritourism.Travel-Guide-Accommodation) - [Cabin Rentals in San Diego](https://expedia.ca/San-Diego-Cabins.d3073-aaCabins.Travel-Guide-Accommodation) - [RV Parks in San Diego](https://expedia.ca/San-Diego-RV-Parks.d3073-aaRVParks.Travel-Guide-Accommodation) - [Condo Resorts in San Diego](https://expedia.ca/San-Diego-Condominium-Resort.d3073-aaCondominiumResort.Travel-Guide-Accommodation) - [Residences in San Diego](https://expedia.ca/San-Diego-Residences.d3073-aaResidences.Travel-Guide-Accommodation) ### Hotels Close to Nearby Airports - [Hotels near San Diego Intl. Airport](https://expedia.ca/San-Diego-Intl-Airport-Hotels.0-aSAN-0.Travel-Guide-Filter-Hotels) - [Hotels near Montgomery Field Airport](https://expedia.ca/Montgomery-Field-Airport-Hotels.0-aMYF-0.Travel-Guide-Filter-Hotels) - [Hotels near Gillespie Field Airport](https://expedia.ca/Gillespie-Field-Airport-Hotels.0-aSEE-0.Travel-Guide-Filter-Hotels) - [Hotels near Brown Field Municipal Airport](https://expedia.ca/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Hotels near McClellan-Palomar Airport](https://expedia.ca/McClellan-Palomar-Airport-Hotels.0-aCLD-0.Travel-Guide-Filter-Hotels) - [Hotels near Oceanside Airport](https://expedia.ca/Oceanside-Airport-Hotels.0-aOCN-0.Travel-Guide-Filter-Hotels) ### Serra Mesa Hotels by Star Rating - [2 Star Hotels in Serra Mesa](https://expedia.ca/2Star-Serra-Mesa-San-Diego-Hotels.s20-n553248635953501652-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Serra Mesa](https://expedia.ca/3Star-Serra-Mesa-San-Diego-Hotels.s30-n553248635953501652-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Serra Mesa](https://expedia.ca/4Star-Serra-Mesa-San-Diego-Hotels.s40-n553248635953501652-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Serra Mesa](https://expedia.ca/5Star-Serra-Mesa-San-Diego-Hotels.s50-n553248635953501652-0.Travel-Guide-Filter-Hotels) ### Serra Mesa Hotels by Brand - [Bartell Hotels Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Bartell-Hotels.0-n553248635953501652-0--bBartellHotels.Travel-Guide-Filter-Hotels) - [Best Western Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Best-Western.0-n553248635953501652-0--bBestWestern.Travel-Guide-Filter-Hotels) - [Hilton Hotels Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Hilton-Hotels.0-n553248635953501652-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Independent Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Independent.0-n553248635953501652-0--bIndependent.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-La-Quinta-Inn-Suites.0-n553248635953501652-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Marriott-Hotels-Resorts.0-n553248635953501652-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Motel-6.0-n553248635953501652-0--bMotel6.Travel-Guide-Filter-Hotels) - [Noble House Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Noble-House.0-n553248635953501652-0--bNobleHouse.Travel-Guide-Filter-Hotels) - [Pacifica Hotels Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Pacifica-Hotels.0-n553248635953501652-0--bPacificaHotels.Travel-Guide-Filter-Hotels) - [Preferred Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Preferred.0-n553248635953501652-0--bPreferred.Travel-Guide-Filter-Hotels) - [Wyndham Extra Holidays Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Wyndham-Extra-Holidays.0-n553248635953501652-0--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels) - [Wyndham Hotels Hotels](https://expedia.ca/Serra-Mesa-San-Diego-Hotels-Wyndham-Hotels.0-n553248635953501652-0--bWyndhamHotels.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Best Western Plus Marina Gateway Hotel](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) - [Hilton San Diego Mission Valley](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) - [San Diego Marriott La Jolla](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) - [Hotel del Coronado, Curio Collection by Hilton](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) - [Pendry San Diego](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) - [Bay Club Hotel & Marina](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) - [The Sofia Hotel](https://expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) - [Legacy Resort Hotel & Spa](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) - [Marriott Marquis San Diego Marina](https://expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) - [Sheraton San Diego Resort](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) - [California Suites Hotel](https://expedia.ca/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) - [Hyatt Regency Mission Bay Spa and Marina](https://expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) [See a list of all hotels in San Diego](https://expedia.ca/All-San-Diego-Hotels.d3073.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Serra Mesa on Expedia.com](https://www.expedia.com/Serra-Mesa-San-Diego-Hotels.0-n553248635953501652-0.Travel-Guide-Filter-Hotels) ### Expedia's Latest Trends Hotels - [Ocean Beach hotels](https://expedia.ca/Ocean-Beach-San-Diego-Hotels.0-n177689-0.Travel-Guide-Filter-Hotels) - [Koreatown hotels](https://expedia.ca/Koreatown-Los-Angeles-Hotels.0-n6156068-0.Travel-Guide-Filter-Hotels) - [Union Square hotels](https://expedia.ca/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels) - [Downtown San Diego hotels](https://expedia.ca/Downtown-San-Diego-San-Diego-Hotels.0-n800123-0.Travel-Guide-Filter-Hotels) - [Downtown San Francisco hotels](https://expedia.ca/Downtown-San-Francisco-San-Francisco-Hotels.0-n6151902-0.Travel-Guide-Filter-Hotels) - [Pacific Beach hotels](https://expedia.ca/Pacific-Beach-San-Diego-Hotels.0-n6185751-0.Travel-Guide-Filter-Hotels) - [Mission Valley hotels](https://expedia.ca/Mission-Valley-San-Diego-Hotels.0-n800124-0.Travel-Guide-Filter-Hotels) - [Downtown Palm Springs hotels](https://expedia.ca/Downtown-Palm-Springs-Palm-Springs-Hotels.0-n6289495-0.Travel-Guide-Filter-Hotels) - [Downtown Los Angeles hotels](https://expedia.ca/Downtown-Los-Angeles-Los-Angeles-Hotels.0-n800058-0.Travel-Guide-Filter-Hotels) - [Little Italy hotels](https://expedia.ca/Little-Italy-San-Diego-Hotels.0-n6161280-0.Travel-Guide-Filter-Hotels) - [Gaslamp Quarter hotels](https://expedia.ca/Gaslamp-Quarter-San-Diego-Hotels.0-n6130021-0.Travel-Guide-Filter-Hotels) - [Fisherman's Wharf hotels](https://expedia.ca/Fishermans-Wharf-San-Francisco-Hotels.0-n800128-0.Travel-Guide-Filter-Hotels) - [Old Town San Diego hotels](https://expedia.ca/Old-Town-San-Diego-San-Diego-Hotels.0-n6347116-0.Travel-Guide-Filter-Hotels) - [Hollywood hotels](https://expedia.ca/Hollywood-Los-Angeles-Hotels.0-n8365-0.Travel-Guide-Filter-Hotels) Packages - [Hollywood Vacations](https://expedia.ca/Hollywood.d8365.Destination-Travel-Guides) General - [Visit Hollywood Hills](https://expedia.ca/Los-Angeles-Hollywood-Hills.dx553248635074843803) - [Visit Fisherman's Wharf](https://expedia.ca/San-Francisco-Fishermans-Wharf.dx800128) - [Visit Downtown San Francisco](https://expedia.ca/San-Francisco-Downtown-San-Francisco.dx6151902) - [Visit Bel Air](https://expedia.ca/Los-Angeles-Bel-Air.dx78229) - [Visit Union Square](https://expedia.ca/San-Francisco-Union-Square.dx800129) - [Visit Ocean Beach](https://expedia.ca/San-Diego-Ocean-Beach.dx177689) - [Visit Crenshaw](https://expedia.ca/Los-Angeles-Crenshaw.dx553248635976008502) - [Visit Little Italy](https://expedia.ca/San-Diego-Little-Italy.dx6161280) - [Visit Pacific Beach](https://expedia.ca/San-Diego-Pacific-Beach.dx6185751) - [Visit Old Town San Diego](https://expedia.ca/San-Diego-Old-Town-San-Diego.dx6347116) - [Visit Laurel Canyon](https://expedia.ca/Los-Angeles-Laurel-Canyon.dx553248635976475747) - [Visit Hollywood](https://expedia.ca/Los-Angeles-Hollywood.dx8365) - [Visit Downtown San Diego](https://expedia.ca/San-Diego-Downtown-San-Diego.dx800123) - [Visit Gaslamp Quarter](https://expedia.ca/San-Diego-Gaslamp-Quarter.dx6130021) - [Visit Downtown Los Angeles](https://expedia.ca/Los-Angeles-Downtown-Los-Angeles.dx800058)