Title: Hotels by Marriott Hotels & Resorts in Serra Mesa from CA $221 | Expedia.ca [Serra Mesa Travel Guide](https://expedia.ca/San-Diego-Serra-Mesa.dx553248635953501652)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Serra Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Serra-Mesa.d553248635953501652.Car-Rental-Guide)[Serra Mesa Vacations](https://expedia.ca/Serra-Mesa.d553248635953501652.Destination-Travel-Guides) ![Aerial view of house in Serra Mesa City in San Diego, California, USA. Green Dry Valley and Villas](https://images.trvl-media.com/place/553248635953501652/8894c002-237b-4878-9643-a4c10cba19ad.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Marriott Hotels & Resorts in Serra Mesa from CA $221 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635953501652&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Serra Mesa Marriott Hotels & Resorts ![2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/5488e3f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/80be4d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/eb8b9673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Marquis San Diego Marina Downtown San Diego 9.2/10 Wonderful (1941) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Farzana CA $220 CA $328 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/8400/8332/21e561fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/8400/8332/4d5866ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/8400/8332/d7a43de0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/8400/8332/d6460a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Marriott Mission Valley Mission Valley 8.8/10 Excellent (1005) "Great room and staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mario CA $192 CA $221 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Mission-Valley.h8332.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/04fbf5a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/a35bbd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/0e02d545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, City View](https://images.trvl-media.com/lodging/1000000/10000/1500/1466/1be27cfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Marriott Gaslamp Quarter Downtown San Diego 8.6/10 Excellent (1588) "All was very nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim CA $199 CA $231 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Gaslamp-Quarter.h1466.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/d7035e73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/ca374c23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/9de84bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Marriott La Jolla University City 8.6/10 Excellent (2172) "Very nice hotel and clean rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Noor CA $215 CA $247 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![3 outdoor pools, open 6:00 AM to 11:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/25300/25270/1a75e8af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/30000/25300/25270/a12b6b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/30000/25300/25270/7c3f6748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, open 6:00 AM to 11:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/25300/25270/0390f2fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coronado Island Marriott Resort & Spa Bayside 8.4/10 Very good (1002) "Excellent service and staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $293 CA $404 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Coronado-Hotels-Coronado-Island-Marriott-Resort-Spa.h25270.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/807600/807521/8d1301b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/810000/807600/807521/bd6ac666.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/810000/807600/807521/c5a858d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/810000/807600/807521/067a05c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Marriott Del Mar Carmel Valley 8.6/10 Excellent (1001) "Highly recommend very comfortable and great staff and excellent service and amazing room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Salomeh CA $234 CA $267 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Diego-Hotels-San-Diego-Marriott-Del-Mar.h807521.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-24&endDate=2025-12-25®ionId=553248635953501652&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSerra-Mesa-San-Diego-Hotels-Marriott-Hotels-Resorts.0-n553248635953501652-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSerra-Mesa-San-Diego-Hotels-Marriott-Hotels-Resorts.0-n553248635953501652-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) ## Top Serra Mesa Hotel Reviews ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Quiet and clean room! Comfortable bed! Friendly staff at check-in! It was wonderful!" [](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Magical" [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "These guy do a terrific job always love coming here. The staff is so friendly and accommodating. We will be back " [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "good" [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Embassy Suites by Hilton San Diego La Jolla](https://images.trvl-media.com/lodging/1000000/10000/8500/8434/49079311_y.jpg) ### Embassy Suites by Hilton San Diego La Jolla 10/10 Excellent "I stayed here every time we would come down here when I was younger on family trips. Now I’m back years later with my boyfriend everything was Perfect and great service all around " [](https://expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-La-Jolla.h8434.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "clean room" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Legacy Resort Hotel & Spa](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego." [](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "The room was great! Loved the view! Staff was so nice! Room service does a great job at making virgin piña colada’s! Great location! only one complaint is it’s a little loud but it quiet down after 10! " [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Hampton Inn & Suites by Hilton San Diego SeaWorld](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "What a great staff on all shifts. I mean everyone was helpful and didn’t have no hesitation to answering questions! They weren’t rude in any way! Great service!!!!! Thank you!!!!" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ## Find out more about Serra Mesa ## Serra Mesa Hotels Guide Expedia.ca offers a selection of 9043 hotels in Serra Mesa. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Serra Mesa. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Serra Mesa neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Serra Mesa, San Diego now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Hilton Hotels in Altadena ](https://www.expedia.ca/Altadena-San-Diego-Hotels-Hilton-Hotels.0-n553248635976472078-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Bay Ho ](https://www.expedia.ca/Bay-Ho-San-Diego-Hotels-Marriott-Hotels-Resorts.0-n553248635976471756-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Birdland Hotels ](https://www.expedia.ca/Birdland-San-Diego-Hotels.0-n553248635976479135-0.Travel-Guide-Filter-Hotels) - [Noble House Hotels in Central San Diego ](https://www.expedia.ca/Central-San-Diego-Hotels-Noble-House.0-0-d6056570--bNobleHouse.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Central San Diego ](https://www.expedia.ca/Central-San-Diego-Hotels-Wyndham-Hotels.0-0-d6056570--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Fiesta Island ](https://www.expedia.ca/Fiesta-Island-Hotels-La-Quinta-Inn-Suites.0-0-d553248621555611981--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - 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