Title: Book the Best Serra Highlands LUXURY Hotels - Upscale Hotels in Serra Highlands, San Francisco | Expedia.ca [Serra Highlands Travel Guide](https://expedia.ca/San-Francisco-Serra-Highlands.dx553248635976474545)[Vacation Rentals in San Francisco](https://expedia.ca/San-Francisco-Vacation-Rentals.d178305.Travel-Guide-VacationRentals)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Serra Highlands Car Rentals](https://expedia.ca/Car-Rentals-In-Serra-Highlands.d553248635976474545.Car-Rental-Guide)[Serra Highlands Vacations](https://expedia.ca/Serra-Highlands.d553248635976474545.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Serra Highlands, San Francisco ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Serra Highlands Luxury Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976474545&startDate=2025-10-24&endDate=2025-10-25&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976474545&startDate=2025-10-25&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976474545&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976474545&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Serra Highlands Luxury Hotels ## Top Serra Highlands Hotel Reviews ![Hotel Riu Plaza Fisherman's Wharf](//images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "We had a very nice room and enjoyed a very large breakfast before heading out to tackle the city." [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Hyatt Centric Fisherman's Wharf San Francisco](//images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg) ### Hyatt Centric Fisherman's Wharf San Francisco 10/10 Excellent "very nice staff" [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Handlery Union Square Hotel](//images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "Fanastic to stay here for our 2nd stay in the city after venturing inland for a few days, it was great to be able to relax by the pool and chill to recharge before a couple more days of sightseeing prior to returning home. The room was big and well appointed." [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Hyatt Regency San Francisco Downtown SOMA ](//images.trvl-media.com/lodging/1000000/10000/500/491/5e565895_y.jpg) ### Hyatt Regency San Francisco Downtown SOMA 10/10 Excellent "Property was excellent " [](https://expedia.ca/San-Francisco-Hotels-The-Park-Central-San-Francisco-Hyatt-Affiliated-Hotel.h491.Hotel-Information) ![Best Western Plus Grosvenor Airport Hotel](//images.trvl-media.com/lodging/1000000/10000/7700/7635/062e9dfe_y.jpg) ### Best Western Plus Grosvenor Airport Hotel 10/10 Excellent "The staff was friendly and checked us in promptly. The room was clean and neat, very spacious. We had a very pleasant stay and our checkout was fast and simple. I would absolutely recommend this hotel! " [](https://expedia.ca/San-Francisco-Hotels-Best-Western-Plus-Grosvenor-Airport-Hotel.h7635.Hotel-Information) ![Club Quarters Hotel in San Francisco](//images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "Nice hotel would stay a" [](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Hyatt Regency San Francisco](//images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc_y.jpg) ### Hyatt Regency San Francisco 10/10 Excellent "The stay was nice. The room was clean. The only thing i would recommend is that the bar area open early on Sundays during nfl season. When you get off your flight you want to wind down and have a cocktail available. Also maybe putting water and coffee in the lobby complementary. Also open the club regency on Sunda for viewing and pictures. " [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information) ![DoubleTree by Hilton Hotel Berkeley Marina](//images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg) ### DoubleTree by Hilton Hotel Berkeley Marina 10/10 Excellent "The parking fee is too high, something else is good " [](https://expedia.ca/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![Fairmont San Francisco](//images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "Nice views!" [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ## Frequently asked questions ### Are you searching for the perfect hotel for your luxury trip to Serra Highlands? > Use Expedia to arrange your flight to San Francisco Intl. Airport (SFO) airport or Oakland Intl. Airport (OAK) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a vacation, so we make it easy to find what you want to make your stay special. If you want an upscale hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Serra Highlands offers. ### What's there to see and do in Serra Highlands? > Experience all that Serra Highlands has to offer when you visit Pier 39, Chase Center, and Oracle Park. 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[Waterpark Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Waterpark-Hotels.0-0-d178305-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in San Francisco](https://www.expedia.ca/San-Francisco-Hotels-Wedding-Hotels.0-0-d178305-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Serramonte](https://www.expedia.ca/Serramonte-San-Francisco-Hotels-Boutique-Hotel.0-n553248635976469617-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Serramonte](https://www.expedia.ca/Serramonte-San-Francisco-Hotels-Couples-Resorts-Hotels.0-n553248635976469617-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Serramonte](https://www.expedia.ca/Serramonte-San-Francisco-Hotels-Hotels-With-Free-Airport-Shuttle.0-n553248635976469617-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Sunshine Gardens](https://www.expedia.ca/Sunshine-Gardens-San-Francisco-Hotels-Beach-Hotel.0-n553248635976470279-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Sunshine Gardens](https://www.expedia.ca/Sunshine-Gardens-San-Francisco-Hotels-Mountain-Hotels.0-n553248635976470279-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Beach-Hotel.0-0-d506142-tBeachHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Cheap-Hotels.0-0-d506142-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Couples-Resorts-Hotels.0-0-d506142-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Family-Hotel.0-0-d506142-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Historic-Hotel.0-0-d506142-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Hotel-With-Pool.0-0-d506142-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-LGBT-Friendly-Hotel.0-0-d506142-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Luxury-Hotel.0-0-d506142-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Pet-Friendly-Hotel.0-0-d506142-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Ski-Hotel.0-0-d506142-tSkiHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Spa-Hotel.0-0-d506142-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotels with Childcare in Union Square](https://www.expedia.ca/Union-Square-San-Francisco-Hotels-Hotels-With-Childcare.0-n800129-0-tHotelswithChildcare.Travel-Guide-Filter-Hotels) - [Book Hotels in Serra Highlands on Expedia.com](https://www.expedia.com/Serra-Highlands-San-Francisco-Hotels-Luxury-Hotel.0-n553248635976474545-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)