Title: Book the Best Serenity Bay LUXURY Hotels - Upscale Hotels in Serenity Bay, Seneca | Expedia.ca

  

[Serenity Bay Travel Guide](https://expedia.ca/Seneca-Serenity-Bay.dx553248635976468572)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Serenity Bay Car Rentals](https://expedia.ca/Car-Rentals-In-Serenity-Bay.d553248635976468572.Car-Rental-Guide)[Serenity Bay Vacations](https://expedia.ca/Serenity-Bay.d553248635976468572.Destination-Travel-Guides)

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# Find Luxury Hotels in Serenity Bay, Seneca

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## Check availability on Serenity Bay Luxury Hotels

Tonight

[Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-22&endDate=2025-10-23&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-23&endDate=2025-10-24&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Top Serenity Bay Luxury Hotels

## Top Serenity Bay Hotel Reviews

![Quality Inn Seneca Clemson Area US-123](//images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg)

### Quality Inn Seneca Clemson Area US-123

10/10 Excellent

"Ok"

[](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

## Frequently asked questions

### Are you searching for the perfect hotel for your luxury getaway to Serenity Bay?

> Expedia can help you get a flight to Greenville-Spartanburg Intl. Airport (GSP) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a trip, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Serenity Bay offers. Serenity Bay has some interesting things to see and do including Lake Keowee, so you might want to take in the local sights during your visit.

### What's there to see and do in Serenity Bay?

> Enjoy Serenity Bay with a stop at Lake Keowee, Keowee Key Golf Course, and Stumphouse Mountain Tunnel. If you have extra time while you're in the area, you might want to stop by Whitewater Lake and Littlejohn Coliseum.

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