Title: Book the Best ADVENTURE Hotels in Serenity Bay in 2025 | Expedia.ca [Serenity Bay Travel Guide](https://expedia.ca/Seneca-Serenity-Bay.dx553248635976468572)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Serenity Bay Car Rentals](https://expedia.ca/Car-Rentals-In-Serenity-Bay.d553248635976468572.Car-Rental-Guide)[Serenity Bay Vacations](https://expedia.ca/Serenity-Bay.d553248635976468572.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels & Resorts for Couples in Serenity Bay, SC from CA $111 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Serenity Bay Hotels & Resorts for Couples Tonight [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-13&endDate=2025-10-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-14&endDate=2025-10-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Serenity Bay Hotels & Resorts for Couples ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-050d425f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center Clemson 8.2/10 Very good (1013) "Great value and great hotel. We would stay there again. " CA $118 CA $131 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/83901eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/188dc421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson Seneca 8.4/10 Very good (620) "Convenient for Clemson visits." CA $125 CA $137 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/a2328ab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/0d515bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/9f5c16fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/64be157e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Clemson Clemson 7.0/10 Good (191) "Great place " CA $105 CA $116 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Clemson-Hotels-Days-Inn-By-Wyndham-Clemson.h15694.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/101000000/100420000/100410200/100410134/58906081.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/101000000/100420000/100410200/100410134/w891h1124x0y1-02793021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100420000/100410200/100410134/w886h1109x0y0-ae2d673d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/101000000/100420000/100410200/100410134/w1706h2155x0y0-531ef83c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Key's Stylish Charm Salem 10/10 Exceptional (1) "The condo was clean and comfortable. Everything we could possibly need was provided. The host was very responsive. We would definitely stay there again. " CA $190 CA $524 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Salem-Hotels-Keowee-Keys-Stylish-Charm.h100410134.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/106000000/105490000/105489100/105489096/96f9fed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105490000/105489100/105489096/dd0e647b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/106000000/105490000/105489100/105489096/baee0ed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/106000000/105490000/105489100/105489096/c1201b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Glamping with a partial lake view, 30 minutes to Clemson University Westminster 9.4/10 Exceptional (14) "Host great communication. Good location. Lake and pool access is .5 miles away from location. Bed is a little uncomfortable. Overall good place to stay for a few nights " CA $125 CA $283 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Westminster-Hotels-Glamping-With-A-Partial-Lake-View.h105489096.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/65000000/64690000/64687300/64687226/8ceb08a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/65000000/64690000/64687300/64687226/c9a2cf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/65000000/64690000/64687300/64687226/43b0dbae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/65000000/64690000/64687300/64687226/a760a8ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Key ~ Cozy Condo ~ Golf Course View - Amenities Salem 10/10 Exceptional (70) "Very nice and clean place to stay, definitely will be back. Excellent communication. " CA $208 CA $515 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Salem-Hotels-Gated-Keowee-Key-Condo-11th-Hole-Balcony-View-Resort-Amenities.h64687226.Hotel-Information) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/67000000/66310000/66300700/66300616/c0d3ca74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66310000/66300700/66300616/0a3efce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66310000/66300700/66300616/307c0c11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66310000/66300700/66300616/7ca3dd80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson House 1 mile from University & Stadium! Clemson 9.6/10 Exceptional (24) "Great accommodations, easy to find. Perfect for our trip. " CA $202 CA $476 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Clemson-Hotels-Clemson-House-1-Mile-From-University-Stadium.h66300616.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/116000000/115160000/115150900/115150808/522b0143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/116000000/115160000/115150900/115150808/ba81f4a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115160000/115150900/115150808/fa96f227.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115160000/115150900/115150808/24117b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Cove Cabin on Lake Hartwell in Townville SC Townville 10/10 Exceptional (8) "Very nice place, and people, would go again." CA $151 CA $246 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Townville-Hotels-Enchanting-1-Bedroom-Cabin-In-Townville.h115150808.Hotel-Information) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/9f69229a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/79b68f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/56ab80ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/dac98c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Seneca / Clemson Area Seneca 6.8/10 (704) "Friendly staff easy check-in. " CA $101 CA $111 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/77000000/76720000/76719400/76719386/a81ad05f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/77000000/76720000/76719400/76719386/1c8955be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/77000000/76720000/76719400/76719386/38db4a14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/77000000/76720000/76719400/76719386/e121f69f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake & Mountain Resort Escape-Pools, Golf, Boat Salem 9.8/10 Exceptional (43) "Perfect place for our stay. Stocked with everything we needed. Tarah was attentive and extremely friendly. Can’t wait to stay again !!!" CA $207 CA $747 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Golf-Mountain-Retreat.h76719386.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-27&endDate=2025-10-28®ionId=553248635976468572&adults=2&nearby_group=recreation&sort=RECOMMENDED&openPlayBack=true) ## Top Serenity Bay Hotel Reviews ![Days Inn by Wyndham Seneca / Clemson Area](//images.trvl-media.com/lodging/1000000/20000/14900/14854/9f69229a_y.jpg) ### Days Inn by Wyndham Seneca / Clemson Area 10/10 Excellent "Friendly staff easy check-in. 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