Title: Book the Best Seneca Knolls LUXURY Hotels - Upscale Hotels in Seneca Knolls, NY | Expedia.ca [Seneca Knolls Travel Guide](https://expedia.ca/Seneca-Knolls.dx6343616)[Hotels in Seneca Knolls](https://expedia.ca/Seneca-Knolls-Hotels.d6343616.Travel-Guide-Hotels)[Vacation Rentals in Seneca Knolls](https://expedia.ca/Seneca-Knolls-Vacation-Rentals.d6343616.Travel-Guide-VacationRentals)[Seneca Knolls Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca-Knolls.d6343616.Car-Rental-Guide)[Seneca Knolls Vacation Packages](https://expedia.ca/Seneca-Knolls.d6343616.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Seneca Knolls, NY ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Seneca Knolls Luxury Hotels Tonight [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=6343616&startDate=2025-10-02&endDate=2025-10-03&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 3 - Oct 4](https://www.expedia.ca/Hotel-Search?regionId=6343616&startDate=2025-10-03&endDate=2025-10-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6343616&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6343616&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Seneca Knolls Luxury Hotels ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/21000/20937/c478bc58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21000/20937/745bfedb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/21000/20937/f4ffec8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21000/20937/7c2a3b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Fairgrounds Syracuse 6.4/10 (588) "Located in an isolated area. Room was dated but clean." CA $113 CA $130 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Syracuse-Hotels-Quality-Inn-Suites-Fairgrounds.h20937.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-16&endDate=2025-10-17®ionId=6343616&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Seneca Knolls Hotel Reviews ![Comfort Inn & Suites Syracuse-Carrier Circle](//images.trvl-media.com/lodging/1000000/10000/6600/6554/acd40bf8_y.jpg) ### Comfort Inn & Suites Syracuse-Carrier Circle 10/10 Excellent "This property is conveniently located off the freeway. Quiet area, easy parking and considerate staff. Free breakfast." [](https://expedia.ca/Syracuse-Hotels-Comfort-Inn-Carrier-Circle.h6554.Hotel-Information) ![Super 8 by Wyndham Liverpool/Syracuse North Airport](//images.trvl-media.com/lodging/1000000/70000/66700/66620/53030acf_y.jpg) ### Super 8 by Wyndham Liverpool/Syracuse North Airport 10/10 Excellent "Overall this was a great hotel! I was nervous to stay because the area seemed unsafe but my room was very clean and the staff were very friendly and helped me figure out the airport shuttle! Would stay again!" [](https://expedia.ca/Syracuse-Hotels-Super-8-By-Wyndham-LiverpoolSyracuse-North-Airport.h66620.Hotel-Information) ![Cresthill Suites Syracuse](//images.trvl-media.com/lodging/1000000/810000/803000/802925/a504d309_y.jpg) ### Cresthill Suites Syracuse 10/10 Excellent "Staff was welcoming. Furniture in room was worn and stained." [](https://expedia.ca/Syracuse-Hotels-Cresthill-Suites-Syracuse.h802925.Hotel-Information) ![The Parkview Hotel](//images.trvl-media.com/lodging/2000000/1200000/1191300/1191281/64f322d8_y.jpg) ### The Parkview Hotel 10/10 Excellent "The free breakfast was a pleasant surprise. The location was perfect for our needs. The bed and bedding were comfortable and the room was plenty big enough. The man staffing the breakfast service was very friendly and personable. " [](https://expedia.ca/Syracuse-Hotels-The-Parkview-Hotel.h1191281.Hotel-Information) ![HomeTown Inn by Red Roof East Syracuse](//images.trvl-media.com/lodging/1000000/480000/470900/470895/ac56d3b6_y.jpg) ### HomeTown Inn by Red Roof East Syracuse 10/10 Excellent "The staff is great" [](https://expedia.ca/Syracuse-Hotels-HomeTown-Inn-By-Red-Roof-East-Syracuse.h470895.Hotel-Information) ![Marriott Syracuse Downtown](//images.trvl-media.com/lodging/1000000/30000/22500/22422/8c1f1a41_y.jpg) ### Marriott Syracuse Downtown 10/10 Excellent "It’s a historic hotel and the details are incredible. Also, one of the best and most filling breakfasts I’ve had in quite some time. " [](https://expedia.ca/Syracuse-Hotels-Marriott-Syracuse-Downtown.h22422.Hotel-Information) ![DoubleTree by Hilton Hotel Syracuse](//images.trvl-media.com/lodging/1000000/10000/8400/8393/ffe32c3c_y.jpg) ### DoubleTree by Hilton Hotel Syracuse 10/10 Excellent "Yes" [](https://expedia.ca/Syracuse-Hotels-DoubleTree-By-Hilton-Syracuse.h8393.Hotel-Information) ![Comfort Inn & Suites Liverpool - Syracuse North](//images.trvl-media.com/lodging/1000000/30000/23700/23659/68e8161d_y.jpg) ### Comfort Inn & Suites Liverpool - Syracuse North 10/10 Excellent "Everything was great, thought they had an indoor pool when I booked, clearly I had not looked amenities. " [](https://expedia.ca/Syracuse-Hotels-Comfort-Inn-Suites.h23659.Hotel-Information) ![Days Inn by Wyndham Syracuse](//images.trvl-media.com/lodging/1000000/20000/13000/12918/a81d98b9_y.jpg) ### Days Inn by Wyndham Syracuse 10/10 Excellent "It was convenient to all shopping areas and excursions we ventured out to." [](https://expedia.ca/Syracuse-Hotels-Days-Inn-By-Wyndham-Syracuse.h12918.Hotel-Information) ## Frequently asked questions ### Are you looking for a luxury hotel for your Seneca Knolls vacation? > Use Expedia to help you arrange a flight to Hancock Intl. Airport (SYR) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Seneca Knolls has to offer. During your visit, you might want to enjoy the restaurants which Seneca Knolls is known for. ### When can I expect good weather in Seneca Knolls? > Planning for the weather is an important factor for making your trip to Seneca Knolls a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 66°F, while the coldest months are January and February with an average of 29°F. The snowiest months in Seneca Knolls are February, January, March, and November, with each month seeing an average of 14 inches of snowfall. ### What's there to see and do in Seneca Knolls? > Enjoy all that Seneca Knolls has to offer and visit Onondaga Lake Park, St. Joseph's Health Amphitheater at Lakeview, and Lake Onondaga. 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