Title: Book the Best Seneca Hotels with smoking rooms in 2025 from CA $98 | Expedia.ca [Hotels in Seneca](https://expedia.ca/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.ca/Seneca.d6548.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/29e46f4f8050a1df2512f3a6a1598c99.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Cindy Keese # Find Smoking Hotels in Seneca, SC from CA $98 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Seneca Hotels with smoking rooms Tonight [Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-23&endDate=2025-10-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Seneca Hotels with smoking rooms ![Exterior](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, desk, laptop workspace](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/52f82f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/313b57b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/877edfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Seneca-Clemson Area Seneca 9.4/10 Exceptional (648) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $206 CA $226 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/441edd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7cb8ae6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/f49d90aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Anderson Anderson 7.6/10 Good (1033) "Rooms were clean, the property was well kept, complimentary breakfast and location is close to everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla CA $88 CA $98 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1130000/1122900/1122844/db913408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/2000000/1130000/1122900/1122844/18d3da59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Jetted Tub) | Bathroom](https://images.trvl-media.com/lodging/2000000/1130000/1122900/1122844/cca88344.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1130000/1122900/1122844/2620d800.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Hartwell Hartwell 9.2/10 Wonderful (326) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $148 CA $177 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Hartwell-Hotels-Hampton-Inn-Hartwell.h1122844.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/a2328ab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/64be157e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/9f5c16fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/11cd707b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Clemson Clemson 7.0/10 Good (193) "Rooms were clean. Check in was easy. TV and AC both worked great. Conveniently located to dining and shopping options. No issues or complaints. Would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean CA $112 CA $124 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Clemson-Hotels-Days-Inn-By-Wyndham-Clemson.h15694.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/e75c3696.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/937af897.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/3e9b7ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/4d4777ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Anderson North I-85 Anderson 7.4/10 Good (41) "Great service and very helpful employees" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Braden CA $104 CA $115 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Anderson-Hotels-Woodspring-Suites-Anderson-North-I-85.h114348655.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/3e16f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/10c576cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/1c4bc101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson Clemson 8.0/10 Very good (1009) "Very nice staff and great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberley CA $105 CA $117 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/b60fead8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/13ba386f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/5a22cd65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/3a6df04f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Anderson Clemson Anderson 7.0/10 Good (823) "Clean room | Staff | Parking | Family-friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vladimir CA $101 CA $112 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Anderson-Hotels-Baymont-By-Wyndham-Anderson-Clemson.h533878.Hotel-Information) ![Free continental breakfast on weekdays](https://images.trvl-media.com/lodging/11000000/10580000/10570900/10570815/f3f791d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10580000/10570900/10570815/e4895a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/11000000/10580000/10570900/10570815/d326e9f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10580000/10570900/10570815/1b233f02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn & Suites Walhalla Walhalla 7.6/10 Good (171) "Comfortable, clean, convenient and well located near nature interests in the area. Perfect for our stay to do white water raft on the Chatooga. Great shower and comfortable beds." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl CA $126 CA $140 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Walhalla-Hotels-Rodeway-Inn-Suites.h10570815.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/620a9c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/87ef0209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/d2634e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/aacced25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Anderson 7.8/10 Good (304) "Good size room and convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick CA $90 CA $99 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Anderson-Hotels-Rodeway-Inn.h4584724.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/17400/17354/7301d79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17400/17354/a87ed015.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/20000/17400/17354/7afb6524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17400/17354/d11baafa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Lavonia 7.8/10 Good (133) "It is a nice hote, very close to the interstate. It is perfect for a rest and a quiet night " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fernando CA $111 CA $134 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Lavonia-Hotels-Rodeway-Inn.h17354.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07®ionId=6548&adults=2&property_amenities_group_explore=designated_smoking_areas&sort=RECOMMENDED&openPlayBack=true) ## Top Seneca Hotel Reviews ![Hampton Inn & Suites Seneca-Clemson Area](//images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 10/10 Excellent "All good. 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