Title: Book the Best Second Mesa FAMILY FRIENDLY Hotels from CA $176 - Kid-Friendly Hotels in Second Mesa, AZ | Expedia.ca [Second Mesa Travel Guide](https://expedia.ca/Second-Mesa.dx553248624339242280)[Hotels in Second Mesa](https://expedia.ca/Second-Mesa-Hotels.d553248624339242280.Travel-Guide-Hotels)[Vacation Rentals in Second Mesa](https://expedia.ca/Second-Mesa-Vacation-Rentals.d553248624339242280.Travel-Guide-VacationRentals)[Things to do in Second Mesa](https://expedia.ca/Things-To-Do-In-Second-Mesa.d553248624339242280.Travel-Guide-Activities)[Second Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Second-Mesa.d553248624339242280.Car-Rental-Guide)[Second Mesa Vacation Packages](https://expedia.ca/Second-Mesa.d553248624339242280.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/197d2580a91a6b51818947d18e1a7a81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Yasser Hamid Syed # Find Family Hotels in Second Mesa, AZ from CA $176 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Second Mesa Family Hotels Tonight [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Tomorrow [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-11-03&endDate=2025-11-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) ## Top Second Mesa Family Hotels ![Restaurant](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/3974928f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Kitchenette, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/c5665f0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/c344ed36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/f66ebcfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hopi Cultural Center Second Mesa 8.2/10 Very good (342) "grateful this hotel is available in this remote area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denver CA $174 CA $176 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=553248624339242280&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Second Mesa Hotel Reviews ![Hopi Cultural Center](//images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/3974928f_y.jpg) ### Hopi Cultural Center 10/10 Excellent "A unique olace to stay on our way to the Grand Canyon. lean, quiet, and a nice restaurant with a selection of Hopi food." [](https://expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information) ## Frequently asked questions ### What's Second Mesa like for family-friendly vacations? > The culturally rich destination of Second Mesa is a great choice if you've been thinking about a vacation with the kids. The excursions and restaurants are just a few things that make this an attractive spot for a family vacation. ### When's the best time to book a family-friendly vacation in Second Mesa? > The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and December with an average of 38°F. Average annual precipitation for Second Mesa is 6 inches. ### What's there to see and do with your family in Second Mesa? > While you and your family are visiting Second Mesa, you might want to get outside and enjoy the great outdoors at spots like Painted Desert. 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