Title: Book the Best BUSINESS Hotels in Second Mesa in 2025 | Expedia.ca [Second Mesa Travel Guide](https://expedia.ca/Second-Mesa.dx553248624339242280)[Hotels in Second Mesa](https://expedia.ca/Second-Mesa-Hotels.d553248624339242280.Travel-Guide-Hotels)[Vacation Rentals in Second Mesa](https://expedia.ca/Second-Mesa-Vacation-Rentals.d553248624339242280.Travel-Guide-VacationRentals)[Things to do in Second Mesa](https://expedia.ca/Things-To-Do-In-Second-Mesa.d553248624339242280.Travel-Guide-Activities)[Second Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Second-Mesa.d553248624339242280.Car-Rental-Guide)[Second Mesa Vacation Packages](https://expedia.ca/Second-Mesa.d553248624339242280.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/197d2580a91a6b51818947d18e1a7a81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Yasser Hamid Syed # Find Business Hotels in Second Mesa, AZ from CA $175 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Second Mesa Business Hotels Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Second Mesa Business Hotels We don't have any properties that match your exact search [See all properties in Second Mesa](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=553248624339242280&adults=2) ## Recommended hotels in Second Mesa ![Restaurant](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/3974928f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Kitchenette, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/c5665f0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/05f397bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/c344ed36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hopi Cultural Center Second Mesa 8.2/10 Very good (342) "grateful this hotel is available in this remote area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denver CA $173 CA $175 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=553248624339242280&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Second Mesa Hotel Reviews ![Hopi Cultural Center](//images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/3974928f_y.jpg) ### Hopi Cultural Center 10/10 Excellent "A unique olace to stay on our way to the Grand Canyon. lean, quiet, and a nice restaurant with a selection of Hopi food." [](https://expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information) ## Frequently asked questions ### Which hotels to stay in Second Mesa as a business traveler? > For business travellers seeking a comfortable stay in Second Mesa, the [Hopi Cultural Center](https://www.expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information) is an excellent choice. This hotel is known for its welcoming atmosphere and offers free WiFi, making it easy to stay connected during your trip. > > > > Guests have praised the rooms for being both comfortable and clean, which is essential for a restful night after a busy day of meetings. The friendly and helpful staff further enhance the overall experience, ensuring that your needs are met promptly and efficiently. > > > > Additionally, the Hopi Cultural Center provides free self-parking, a convenience that is particularly beneficial for those travelling with a vehicle. ### How much does a business hotel in Second Mesa cost? > Take advantage of staying in a business hotel in Second Mesa, with plenty of hotels from CA $175 offering top amenities. If you're leaning toward a little luxury, prices can rise, and vary here depending on the location, season, and hotel amenities. ### Which area of Second Mesa is best to stay in for business? > Second Mesa, Arizona, is a captivating destination known for its rich Hopi culture and stunning desert landscapes. For business travellers, the best area to stay is near the Hopi Cultural Center. This location not only provides convenient access to key business facilities but also immerses you in the unique heritage of the Hopi people. The centre features a restaurant, a gift shop, and a museum that offers a fascinating insight into local traditions, making it superb for a blend of work and leisure. > > > > For those travelling with colleagues or clients, the proximity to meeting spaces and communal areas enhances networking opportunities. The serene surroundings allow for a productive atmosphere while offering a chance to explore the breathtaking views of the mesas. > > > > If you're a solo traveller looking for a quiet retreat after a busy day, staying near the cultural centre provides a peaceful environment. You can unwind by enjoying local art and taking leisurely walks around the area, enriching your experience while still focusing on your professional commitments. ### What are the best Second Mesa business hotels with meeting rooms? > The [Hopi Cultural Center](https://www.expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information) is an excellent choice for business travellers seeking a comfortable and functional stay in Second Mesa. With an excellent traveller rating of 8.2, this hotel is popular for its comfortable and clean rooms, ensuring you have a restful environment to recharge after a busy day of meetings. > > > > For those needing space to conduct meetings, the Hopi Cultural Center features multiple meeting rooms, making it a practical option for corporate gatherings. Additionally, you can enjoy complimentary WiFi throughout the property, allowing for seamless connectivity and communication during your stay. > > > > Guests have praised the friendly and helpful staff, adding a personal touch to your business experience. Plus, with free self-parking available, you can easily access your vehicle without any added hassle, making your journey to and from meetings more convenient. ### What business amenities should I look for in a hotel in Second Mesa? > When choosing a hotel for business travel in Second Mesa, it's important to find one that supports both productivity and comfort. Having reliable, high-speed Wi-Fi and a comfortable workspace in your room can make it much easier to stay focused and connected. Many hotels also offer business centres and meeting rooms, which are perfect for networking and hosting meetings. 24/7 front desk service and security provide added convenience and peace of mind, while amenities like an on-site fitness centre, dining options, and laundry services help balance work with relaxation. Additionally, easy access to public transportation or on-site parking ensures a smooth, hassle-free experience. ### How can I save on a business hotel in Second Mesa with Expedia? > [One Key™](https://www.expedia.ca/welcome-one-key) members always get our best prices. Find our best Second Mesa business hotel deals by joining Expedia's free travel rewards program. As a member, you can unlock instant savings and member perks when you're logged in. Typically, booking in advance will help you save on your business hotel booking. But, if you're making a last-minute reservation, be sure to check for last-minute deals. ### Can I cancel my business hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right business hotel in Second Mesa for you. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Hotels near Coal Mine Canyon](https://www.expedia.ca/Coal-Mine-Canyon-Hotels.0-l6295487-0.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Navajo County](https://www.expedia.ca/Destinations-In-Navajo-County-Beach-Hotel.0-0-d553248635976431975-tBeachHotel.Hotel-Filter-Destinations) - [Luxury Hotels in Navajo County](https://www.expedia.ca/Destinations-In-Navajo-County-Luxury-Hotel.0-0-d553248635976431975-tLuxuryHotel.Hotel-Filter-Destinations) - [Pet-Friendly Hotels in Navajo County](https://www.expedia.ca/Destinations-In-Navajo-County-Pet-Friendly-Hotel.0-0-d553248635976431975-tPetfriendlyHotel.Hotel-Filter-Destinations) - [Navajo County Hotels](https://www.expedia.ca/Destinations-In-Navajo-County.d553248635976431975.Hotel-Destinations) - 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