Title: Book the Best BUSINESS Hotels in Second Mesa in 2026 | Expedia.ca

[Second Mesa Travel Guide](https://expedia.ca/Second-Mesa.dx553248624339242280)[Hotels in Second Mesa](https://expedia.ca/Second-Mesa-Hotels.d553248624339242280.Travel-Guide-Hotels)[Vacation Rentals in Second Mesa](https://expedia.ca/Second-Mesa-Vacation-Rentals.d553248624339242280.Travel-Guide-VacationRentals)[Second Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-Second-Mesa.d553248624339242280.Car-Rental-Guide)[Second Mesa Vacation Packages](https://expedia.ca/Second-Mesa.d553248624339242280.Destination-Travel-Guides)

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# Find Business Hotels in Second Mesa, AZ from CA $173

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## Check availability on Second Mesa Business Hotels

Tonight

[Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Dec 23 - Dec 24](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248624339242280&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

No exact matches found, but these alternatives could be just right

## Recommended hotels in Second Mesa

![Restaurant](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/3974928f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/f66ebcfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/05f397bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Kitchenette, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/c5665f0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hopi Cultural Center

[](https://www.expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information)

Second Mesa

8.4/10

Very good

(346)

"grateful this hotel is available in this remote area"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denver

CA $171

CA $173 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-05&endDate=2026-01-06&regionId=553248624339242280&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Second Mesa Hotel Reviews

![Hopi Cultural Center](https://images.trvl-media.com/lodging/18000000/17070000/17067800/17067718/3974928f_y.jpg)

### Hopi Cultural Center

10/10 Excellent

"It was a really nice stay I really appreciate and admire that they waited for me to check in late after driving from Buckeye AZ. The staff in both the hotel and restaurant where very professional in thier appearance and their demeanor was very friendly along with comforting. Thanks staff keep up the good work if I could I would give you all a grade A+ "

[](https://expedia.ca/Second-Mesa-Hotels-Hopi-Cultural-Center.h17067718.Hotel-Information)

## Frequently asked questions

### Which hotels to stay in Second Mesa as a business traveler?

> Guests have praised the rooms for being both comfortable and clean, which is essential for a restful night after a busy day of meetings. The friendly and helpful staff further enhance the overall experience, ensuring that your needs are met promptly and efficiently.
> 
>   
> Additionally, the Hopi Cultural Center provides free self-parking, a convenience that is particularly beneficial for those travelling with a vehicle.

### How much does a business hotel in Second Mesa cost?

### Which area of Second Mesa is best to stay in for business?

> For those travelling with colleagues or clients, the proximity to meeting spaces and communal areas enhances networking opportunities. The serene surroundings allow for a productive atmosphere while offering a chance to explore the breathtaking views of the mesas.
> 
>   
> If you're a solo traveller looking for a quiet retreat after a busy day, staying near the cultural centre provides a peaceful environment. You can unwind by enjoying local art and taking leisurely walks around the area, enriching your experience while still focusing on your professional commitments.

### What are the best Second Mesa business hotels with meeting rooms?

> For those needing space to conduct meetings, the Hopi Cultural Center features multiple meeting rooms, making it a practical option for corporate gatherings. Additionally, you can enjoy complimentary WiFi throughout the property, allowing for seamless connectivity and communication during your stay.
> 
>   
> Guests have praised the friendly and helpful staff, adding a personal touch to your business experience. Plus, with free self-parking available, you can easily access your vehicle without any added hassle, making your journey to and from meetings more convenient.

### What business amenities should I look for in a hotel in Second Mesa?

### How can I save on a business hotel in Second Mesa with Expedia?

### Can I cancel my business hotel reservation on Expedia?

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