Title: Scott County Vacation Home Rentals from CA $143: Search Top Private Vacation Homes for Rent | Expedia.ca [Scott County Hotels](https://expedia.ca/Destinations-In-Scott-County.d553248635976434022.Hotel-Destinations)[Vacation Rentals in Scott County](https://expedia.ca/Destinations-In-Scott-County.d553248635976434022.Vacation-Rental-Destinations)[Scott County Car Rentals](https://expedia.ca/Destinations-In-Scott-County.d553248635976434022.Car-Rental-Destinations)[Scott County Vacations](https://expedia.ca/Scott-County.d553248635976434022.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/5577d4f4e06a1f16f36627e14e747edc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Kurt Easterwood # Scott County Vacation Rentals ## Compare and save - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976434022&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976434022&startDate=2025-11-21&endDate=2025-11-23&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248635976434022&startDate=2025-12-05&endDate=2025-12-07&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976434022&startDate=2026-01-02&endDate=2026-01-04&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cities in Scott County ![](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Sikeston [](https://expedia.ca/Sikeston-Private-Vacation-Homes.d6058766-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Featured Vacation Homes in Scott County ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/29617056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/ec557893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/c59bcf0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space Cape Girardeau 10/10 Exceptional (145) "Three generations found rest,beauty,& joy at Serenity South. Thoughtful touches,beautiful gardens and Cape charm made this more than a stay-it became a treasured memory. We were so appreciative of the details, the fresh flowers, homemade cookies, the coffeemaker upstairs and the books and games. The beds were all comfortable. We enjoyed this historical home and our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linden S. CA $211 CA $344 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/ebfa2413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, music library, stereo](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/9a37fcb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/48d5828e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/cf643107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban 2-bedroom Escape in Downtown Cape Girardeau Cape Girardeau 10/10 Exceptional (7) "We had the best girls’ getaway here! The place was super clean and well decorated. We had everything we needed, and the host was friendly and quick to respond. The location was perfect—lots of shops, restaurants, and even a spa all within walking distance. We couldn’t have asked for a better spot!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric B. [](https://www.expedia.ca/Cape-Girardeau-Hotels-Urban-2-Bedroom-Escape-In-Downtown-Cape-Girardeau.h109929505.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/1e8bea93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/ad11073b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Blue Cottage on Spanish Cape Girardeau 8.6/10 Excellent (46) "We stayed here to visit our two children going to SEMO. Everything about the place was perfect for a couple. The place was cute and the location was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth G. CA $114 CA $143 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120670000/120661800/120661701/7d35641a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/121000000/120670000/120661800/120661701/75249d64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120670000/120661800/120661701/d7c65aa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/121000000/120670000/120661800/120661701/da9b2a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau Cape Girardeau 10/10 Exceptional (1) "House is conveniently located close to campus. Plenty of room for us and we had a great stay. Highly recommend. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas C. [](https://www.expedia.ca/Cape-Girardeau-Hotels-3-Bedroom-3-Full-Bath-In-Beautiful-Historic-District-Downtown-Cape-Girardeau.h120661701.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/b002a425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/66471bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/6a5a3c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/1e923d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau Cape Girardeau 10/10 Exceptional (26) "Lovely home perfect for our weekend celebrating our daughter’s graduation. Chip was an excellent host, even found us champagne flutes! Beds were comfortable, house was clean and nicely decorated. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jill B. [](https://www.expedia.ca/Cape-Girardeau-Hotels-Remodeled-1920s-Dutch-Colonial-Revival-In-Downtown-Cape-Girardeau.h76544096.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/74000000/73250000/73241700/73241636/d1793f5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/74000000/73250000/73241700/73241636/5ea71602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/74000000/73250000/73241700/73241636/w1787h960x0y0-328ad9de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/74000000/73250000/73241700/73241636/2aaac254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quaint, Beautiful Home next to SEMO and Hospital Cape Girardeau 9.8/10 Exceptional (41) "Quaint, little property with roomy accommodations. So much better than 4 people sharing a hotel room…everyone had their own space. The location was convenient, quiet and the neighborhood felt safe." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily G. [](https://www.expedia.ca/Cape-Girardeau-Hotels-Quaint.h73241636.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/113000000/112630000/112624300/112624271/403251a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112630000/112624300/112624271/a7405e78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/113000000/112630000/112624300/112624271/02b08ccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, toilet paper](https://images.trvl-media.com/lodging/113000000/112630000/112624300/112624271/35b4ae99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy upstairs unit in Cape Girardeau Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Cozy-Upstairs-Unit-In-Cape-Girardeau.h112624271.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/d510bdd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/db0f0531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/25fbc7e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout. Tamms 10/10 Exceptional (23) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy P. [](https://www.expedia.ca/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/bcbc8581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/81932f13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/7298889d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/1136aaf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool Cape Girardeau 8.8/10 Excellent (34) "Loved this location for our FFA Officer Retreat! Lots of things to do for high school aged students and space to getting planning done for the school year. Loved the outdoor fire pit and pool. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ann P. CA $191 CA $306 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/w1320h1474x0y0-c28d188d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/w1320h1756x0y0-48d6becd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/1dd8c683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/d10dae1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom with AC, WiFi in lovely Jonesboro Jonesboro 10/10 Exceptional (1) "Our stay at 1898 was lovely!! Clean and comfortable! Will stay again when we head back south to visit family! Thank you!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim K. CA $169 CA $377 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Jonesboro-Hotels-Charming-2-Bedroom-With-AC.h118734902.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/2cc8556c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/07e510a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/67038c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/d2b33581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More Cape Girardeau 9.6/10 Exceptional (7) "Nice place, great times" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jace W. CA $378 CA $615 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-4-Bedroom-Home-2-King-Beds.h111971489.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/95000000/95000000/94995100/94995011/7c85a256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/95000000/95000000/94995100/94995011/60f4a6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/95000000/95000000/94995100/94995011/f263ed8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/95000000/95000000/94995100/94995011/3744ed36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi Cape Girardeau 10/10 Exceptional (8) "We came for a weekend family girls trip. Location was great, walkable to everything. Lots of space, clean, had everything we needed. One shower was tricky, but we managed. Thank goodness for two toilets!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina H. [](https://www.expedia.ca/Cape-Girardeau-Hotels-Historic-Victorian-Walkable-To-Downtown-Cape-Girardeau-King-Bed-Fast-Wifi.h94995011.Hotel-Information) ![Smart TV, fireplace, stereo](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/65f4c520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/w995h683x16y0-2dd69499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/de8fdc64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/1c277e81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dexter Homestead. Very Cozy & NEW Remodel ! Dexter 8.0/10 Very good (26) "Plenty of room to move about. Quiet neighborhood. Host took care of all our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barry W. CA $126 CA $275 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Dexter-Hotels-Dexter-Homestead-Very-Cozy-NEW-Remodel.h63162828.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/dc959c59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/beddceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/54de22e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/d1b53ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Next Door to Mercy Hospital - Pet Friendly - Fast Wifi Cape Girardeau 8.0/10 Very good (5) "Very clean and comfortable. I would have like either a bench or chair for my luggage, and I would have liked the door going to the backyard useable. Other from that we very much loved the house." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cleta [](https://www.expedia.ca/Cape-Girardeau-Hotels-Next-Door-To-Mercy-Hospital-Pet-Friendly-Fast-Wifi.h103701368.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88620000/88611300/88611252/1c9cad7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88620000/88611300/88611252/2bacb634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88620000/88611300/88611252/cad6a7f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/89000000/88620000/88611300/88611252/900daa82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Steps to Southeast Hospital - Fast Wifi - King Bed Cape Girardeau 10/10 Exceptional (6) "Everything about the stay was flawless. The instructions and communication prior to arrival were complete and clear. The property was clean, stocked with basic necessities and the location is better than what is in the listing description." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) thomas w. [](https://www.expedia.ca/Cape-Girardeau-Hotels-Steps-To-Southeast-Hospital-Fast-Wifi-King-Bed.h88611252.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88620000/88611400/88611380/0ed40912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88620000/88611400/88611380/e01181cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/89000000/88620000/88611400/88611380/4799a9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88620000/88611400/88611380/fb43e012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi Cape Girardeau 10/10 Exceptional (4) "This was a great place for us to stay while in town for a family emergency. We will be staying here again the next time we visit. Great communication, comfortable beds, clean and fully stocked with supplies." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole L. [](https://www.expedia.ca/Cape-Girardeau-Hotels-Large-Home-Next-To-Southeast-Hospital-2-King-Beds-Fast-Wifi.h88611380.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611639/54402f57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611639/7666626b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611639/e1c62c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611639/9f8ae2ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic 2-Story Foursquare Home - C.1847 - River Views - Fast Wifi Cape Girardeau 9.6/10 Exceptional (15) "Great location, only a few blocks from downtown." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacob J. [](https://www.expedia.ca/Cape-Girardeau-Hotels-Historic-2-Story-Foursquare-Home-C1847-River-Views-Fast-Wifi.h88611639.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/97000000/96120000/96115700/96115627/b69a0fc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/97000000/96120000/96115700/96115627/1ab7c4d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/97000000/96120000/96115700/96115627/42ff5262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96120000/96115700/96115627/2d4328c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Setting & Views - Garage Parking - Fast Wifi Jackson 8.0/10 Very good (1) "Very nice property in a very nice location. Overall a nice place to stay. Pros: 1) House by itself on a large piece of land 2) Very quiet and peaceful 3)House is large with plenty of room 4) Nicely remodeled with very nice furnishings 5) The one bed we slept on was very comfortable 6) Amazing view of the sun coming up over the hill in the mornings Cons: 1) Although newly remodeled, it's still a very old house and the old house smell is crazy strong. I mean VERY strong 2) The smart thermostat... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex M. [](https://www.expedia.ca/Jackson-Hotels-Country-Setting-Views-Garage-Parking-Fast-Wifi.h96115627.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/w1179h2041x0y495-85de3d2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/e6834e40_edited_d3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/631b4eca_edited_1098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/b1eb2df2_edited_275e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house near downtown Cape Girardeau 10/10 Exceptional (2) "My husband and I along with one other couple stayed here while in Cape for a wedding. The location was nice and was a short distance for driving or Ubering around town. The price was great!! Highly recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle U. [](https://www.expedia.ca/Cape-Girardeau-Hotels-Charming-3-Bedroom-House-Near-Downtown.h107909366.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/a162857d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/5bee6b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/1be1ed6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/ac265433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house in delightful Advance with AC, WiFi Advance 10/10 Exceptional (4) "Lovely, clean home. Close to family for visit." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debbie B. [](https://www.expedia.ca/Advance-Hotels-Charming-3-Bedroom-House-In-Delightful-Advance-With-AC.h103362449.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-22&endDate=2025-11-23®ionId=553248635976434022&adults=2&lodging=VACATION_HOME&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FScott-County-Private-Vacation-Homes.d553248635976434022-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FScott-County-Private-Vacation-Homes.d553248635976434022-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Scott County Hotel Reviews ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "1 of the best places ive stayed at! Extremely friendly service, 530 kickback which includes food and cocktails...and a decent breakfast. Room was nice..bed super comfy, pool area clean and nice.. Superb place for the price. Manager on duty was fantastic...all the staff were super friendly. " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The room was clean and comfy. The staf was friendly, courteous and efficient. Many thanks!" [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "Excellent place to stay." [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean room, great location and friendly staff" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "The eggs were fake and the turkey sausage was bad " [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Always great service and awesome accomodations." [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Good breakfast options. Reasonable rate. Clean" [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Great service " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](//images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "Fairly new building in a new area of town. Very convenient as right off the freeway. 2 Q room, typical Fairfield bath setup except a tub/shower instead of shower as we’ve seen in every other Fairfields. Ave size room but adequate. Good cleanliness. Good breakfast, cage free eggs, bacon, sausage, 2 waffle makers, etc, good coffee. We would stay here again if needed. " [](https://expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ## Find out more about Scott County ## Scott County Vacation Homes information | Number of reviews | 382 | | --- | --- | | Accommodation | 38 Vacation Homes | | Lowest Price | CA $143 | | Highest Price | CA $613 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [B&B in Advance](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Lodges in Advance](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - [Motels in Advance](https://www.expedia.ca/Advance-Motels.d553248634983475122-aaMotels.Travel-Guide-Accommodation) - [Apartments in Baker](https://www.expedia.ca/Baker-Apartments.d553248634983252914-aaApartments.Travel-Guide-Accommodation) - [Apartments in Bell City](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - 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