Title: Scott County Vacation Home Rentals from CA $142: Search Top Private Vacation Homes for Rent | Expedia.ca [Scott County Hotels](https://expedia.ca/Destinations-In-Scott-County.d553248635976434022.Hotel-Destinations)[Vacation Rentals in Scott County](https://expedia.ca/Destinations-In-Scott-County.d553248635976434022.Vacation-Rental-Destinations)[Scott County Car Rentals](https://expedia.ca/Destinations-In-Scott-County.d553248635976434022.Car-Rental-Destinations)[Scott County Vacations](https://expedia.ca/Scott-County.d553248635976434022.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/5577d4f4e06a1f16f36627e14e747edc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Kurt Easterwood # Scott County Vacation Rentals ## Compare and save ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976434022&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976434022&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976434022&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976434022&startDate=2025-12-12&endDate=2025-12-14&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Featured Vacation Homes in Scott County ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/927199d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/ad11073b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Blue Cottage on Spanish Cape Girardeau 8.6/10 Excellent (43) "We enjoy every time we stay here . We have stayed her many times. There is some repairs that need to be done . Also I think there needs to be a better way to cook besides a microwave. " CA $114 CA $142 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/29617056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/c59bcf0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/ec557893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/6b76cbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space Cape Girardeau 10/10 Exceptional (144) "Beautiful house. Great stay. Would definitely stay again!" CA $211 CA $344 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) ![WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/8f220eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/d10dae1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/w1320h1756x0y0-48d6becd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118740000/118735000/118734902/w1320h989x0y0-73e73ec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom with AC, WiFi in lovely Jonesboro Jonesboro 10/10 Exceptional (1) "Our stay at 1898 was lovely!! Clean and comfortable! Will stay again when we head back south to visit family! Thank you!!! " CA $169 CA $375 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Jonesboro-Hotels-Charming-2-Bedroom-With-AC.h118734902.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/b002a425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/6a5a3c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/c93cba87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/66471bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau Cape Girardeau 10/10 Exceptional (23) "Group of ladies came and loved this little gem. Chip was a wonderful and gracious host. Fresh flowers and snacks were waiting for us! The history that comes with the property is amazing. Can’t say enough good things and would definitely stay again." [](https://www.expedia.ca/Cape-Girardeau-Hotels-Remodeled-1920s-Dutch-Colonial-Revival-In-Downtown-Cape-Girardeau.h76544096.Hotel-Information) ![Smart TV, fireplace, stereo](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/65f4c520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/w995h683x16y0-2dd69499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/1c277e81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/64000000/63170000/63162900/63162828/de8fdc64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dexter Homestead. Very Cozy & NEW Remodel ! Dexter 8.0/10 Very good (26) "What a relaxing stay! Nicely decorated house, plenty of space, and we appreciated the covered parking. " CA $125 CA $276 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Dexter-Hotels-Dexter-Homestead-Very-Cozy-NEW-Remodel.h63162828.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/d510bdd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/25fbc7e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/db0f0531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout. Tamms 10/10 Exceptional (22) "Great place to stay. " [](https://www.expedia.ca/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/95000000/95000000/94995100/94995011/7c85a256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/95000000/95000000/94995100/94995011/f263ed8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/95000000/95000000/94995100/94995011/3744ed36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/95000000/94995100/94995011/fd9228ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi Cape Girardeau 10/10 Exceptional (8) "We thoroughly enjoyed the property. Very unique and fun. " [](https://www.expedia.ca/Cape-Girardeau-Hotels-Historic-Victorian-Walkable-To-Downtown-Cape-Girardeau-King-Bed-Fast-Wifi.h94995011.Hotel-Information) ![Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/114000000/113360000/113359900/113359853/bd0192f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/114000000/113360000/113359900/113359853/1a6d79fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/114000000/113360000/113359900/113359853/726bdd5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113360000/113359900/113359853/9e23b0dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super cute family friendly 3-bedroom house in Cape Girardeau with AC, WiFi Cape Girardeau [](https://www.expedia.ca/Cape-Girardeau-Hotels-Super-Cute-Family-Friendly-3-Bedroom-House-In-Cape-Girardeau-With-AC.h113359853.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/bcbc8581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/5e48ce91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/7298889d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/81932f13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool Cape Girardeau 8.8/10 Excellent (34) "Abbie was an amazing hostess. She was great with communicating with our group and made our stay awesome. She was very accommodating and made sure we had everything we needed to make our trip perfect. The house and pool were great. We were very pleased. " CA $190 CA $299 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/ebfa2413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/48d5828e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/1dbbb19d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, music library, stereo](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/9a37fcb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban 2-bedroom Escape in Downtown Cape Girardeau Cape Girardeau 10/10 Exceptional (6) "We had the best girls’ getaway here! The place was super clean and well decorated. We had everything we needed, and the host was friendly and quick to respond. The location was perfect—lots of shops, restaurants, and even a spa all within walking distance. We couldn’t have asked for a better spot!" [](https://www.expedia.ca/Cape-Girardeau-Hotels-Urban-2-Bedroom-Escape-In-Downtown-Cape-Girardeau.h109929505.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/2cc8556c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/77eb14c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/67038c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/07e510a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More Cape Girardeau 9.6/10 Exceptional (7) "Nice place, great times" CA $378 CA $614 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Cape-Girardeau-Hotels-4-Bedroom-Home-2-King-Beds.h111971489.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/74000000/73250000/73241700/73241636/d1793f5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/74000000/73250000/73241700/73241636/w1787h960x0y0-328ad9de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/74000000/73250000/73241700/73241636/5ea71602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/74000000/73250000/73241700/73241636/2aaac254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quaint, Beautiful Home next to SEMO and Hospital Cape Girardeau 9.8/10 Exceptional (40) "Great stay, great location! " [](https://www.expedia.ca/Cape-Girardeau-Hotels-Quaint.h73241636.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/w1179h2041x0y495-85de3d2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/w1179h722x0y917-d1ed59ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/b1eb2df2_edited_275e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107910000/107909400/107909366/631b4eca_edited_1098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house near downtown Cape Girardeau 10/10 Exceptional (2) "My husband and I along with one other couple stayed here while in Cape for a wedding. The location was nice and was a short distance for driving or Ubering around town. The price was great!! Highly recommend." [](https://www.expedia.ca/Cape-Girardeau-Hotels-Charming-3-Bedroom-House-Near-Downtown.h107909366.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88620000/88611300/88611252/1c9cad7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88620000/88611300/88611252/cad6a7f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/89000000/88620000/88611300/88611252/900daa82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88620000/88611300/88611252/2bacb634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Steps to Southeast Hospital - Fast Wifi - King Bed Cape Girardeau 10/10 Exceptional (6) "This was the perfect place for us to have a small group weekend getaway! All the beds were comfy! High quality sheets! Very clean! " [](https://www.expedia.ca/Cape-Girardeau-Hotels-Steps-To-Southeast-Hospital-Fast-Wifi-King-Bed.h88611252.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115550000/115546400/115546303/89e8488f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/116000000/115550000/115546400/115546303/5cb710cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/116000000/115550000/115546400/115546303/98a53ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/116000000/115550000/115546400/115546303/3d070bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury 4BR w/ King Bed | Fast Wi-Fi | Private Yard Jackson 10/10 Exceptional (2) "The house was absolutely perfect. Very accommodating, Had everything we needed and more. Would definitely recommend and would rent again!!" [](https://www.expedia.ca/Jackson-Hotels-Luxury-4BR-W-King-Bed-Fast-Wi-Fi-Private-Yard.h115546303.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611639/54402f57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611639/2bc6390a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611639/9f8ae2ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611639/e1c62c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic 2-Story Foursquare Home - C.1847 - River Views - Fast Wifi Cape Girardeau 9.6/10 Exceptional (15) "Wonderful older house with great updates! Beds were comfortable and the yard lovely. " [](https://www.expedia.ca/Cape-Girardeau-Hotels-Historic-2-Story-Foursquare-Home-C1847-River-Views-Fast-Wifi.h88611639.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88620000/88611400/88611380/0ed40912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/89000000/88620000/88611400/88611380/4799a9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88620000/88611400/88611380/fb43e012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88620000/88611400/88611380/e01181cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi Cape Girardeau 10/10 Exceptional (4) "The property was nice, spacious, and easy access to everything! We enjoyed our stay!" [](https://www.expedia.ca/Cape-Girardeau-Hotels-Large-Home-Next-To-Southeast-Hospital-2-King-Beds-Fast-Wifi.h88611380.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/dc959c59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/f42a73b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/beddceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103710000/103701400/103701368/54de22e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Next Door to Mercy Hospital - Pet Friendly - Fast Wifi Cape Girardeau 8.0/10 Very good (5) "Great place for our family to have a quick get together in short notice." CA $230 CA $560 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Next-Door-To-Mercy-Hospital-Pet-Friendly-Fast-Wifi.h103701368.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112320000/112311900/112311879/45e4d2a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/113000000/112320000/112311900/112311879/90578d24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/113000000/112320000/112311900/112311879/3e320692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112320000/112311900/112311879/81048764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom house in delightful Jackson with AC, WiFi Jackson 10/10 Exceptional (5) "Nice clean property second stay." [](https://www.expedia.ca/Jackson-Hotels-Charming-2-Bedroom-House-In-Delightful-Jackson-With-AC.h112311879.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/a162857d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/5bee6b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/ac265433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/1be1ed6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house in delightful Advance with AC, WiFi Advance 10/10 Exceptional (4) "Lovely, clean home. Close to family for visit." [](https://www.expedia.ca/Advance-Hotels-Charming-3-Bedroom-House-In-Delightful-Advance-With-AC.h103362449.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31®ionId=553248635976434022&adults=2&lodging=VACATION_HOME&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FScott-County-Private-Vacation-Homes.d553248635976434022-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FScott-County-Private-Vacation-Homes.d553248635976434022-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Scott County Hotel Reviews ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Room was a bit on the small side, but comfortable." [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Very clean felt safe" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Great staff " [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Very clean room as were all the facilities I used...Staff very friendly & helpful. " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Clean room. " [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased. " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Best Western Plus Sikeston](//images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Room was clean and relaxing." [](https://expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Country Yard Inn and Suite](//images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182_y.jpg) ### Country Yard Inn and Suite 8/10 Good "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." [](https://expedia.ca/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe " [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ## Find out more about Scott County ## Scott County Vacation Homes information | Number of reviews | 371 | | --- | --- | | Accommodation | 38 Vacation Homes | | Lowest Price | CA $142 | | Highest Price | CA $614 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [B&B in Advance](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Lodges in Advance](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - [Motels in Advance](https://www.expedia.ca/Advance-Motels.d553248634983475122-aaMotels.Travel-Guide-Accommodation) - [Apartments in Baker](https://www.expedia.ca/Baker-Apartments.d553248634983252914-aaApartments.Travel-Guide-Accommodation) - [Apartments in Bell City](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - 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