Title: São Tomé Island Vacation Home Rentals from CA $203: Search Top Private Vacation Homes for Rent | Expedia.ca [São Tomé Island Travel Guide](https://expedia.ca/Sao-Tome-Island.dx3486)[Hotels in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Hotels.d3486.Travel-Guide-Hotels)[Vacation Rentals in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Vacation-Rentals.d3486.Travel-Guide-VacationRentals)[Flights to São Tomé Island](https://expedia.ca/Cheap-Flights-To-Sao-Tome-Island.d3486.Travel-Guide-Flights)[São Tomé Island Car Rentals](https://expedia.ca/Car-Rentals-In-Sao-Tome-Island.d3486.Car-Rental-Guide)[São Tomé Island Vacation Packages](https://expedia.ca/Sao-Tome-Island.d3486.Destination-Travel-Guides) ![Nice place, good food... Quite difficult to reach, you need a good car...](https://images.trvl-media.com/place/553248621565299214/edf5448a-52b1-44ed-852d-bc5327dd1c36.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Fabrice Récalt ![](https://images.trvl-media.com/place/553248621565299214/edf5448a-52b1-44ed-852d-bc5327dd1c36.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 19 - Jun 21](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 17 - Jul 19](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for São Tomé Island vacation homes ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/8c12cec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/ee79bee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/ff5a22d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/dfafa2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alojamento Santos Silva [](https://www.expedia.ca/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information) São Tomé CA $430 CA $496 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107460000/107456900/107456850/e6477092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107460000/107456900/107456850/17dae98b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107460000/107456900/107456850/a0b280a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107460000/107456900/107456850/0fcb5962.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### endless horizon - Cozy house in charming Santana with WiFi [](https://www.expedia.ca/Santana-Hotels-Endless-Horizon-Cozy-House-In-Charming-Santana-With-WiFi.h107456850.Hotel-Information) Santana 10/10 Exceptional (1 review) "We really enjoyed our stay at the Endless Horizon. Joao and Alexander were always there to help out with things. We loved the high ceilings and of course the amazing view. The bed was very comfortable and the shower was wonderful; specious and with nice hot water. We would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Silvard K. CA $127 CA $203 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Santana-Hotels-Endless-Horizon-Cozy-House-In-Charming-Santana-With-WiFi.h107456850.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-06&endDate=2026-04-07®ionId=3486&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Villas [](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+Island%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=3486&latLong=0.259533%2C6.621318&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=VILLA) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+Island%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=3486&latLong=0.259533%2C6.621318&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=VACATION_HOME) Apartments [](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+Island%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=3486&latLong=0.259533%2C6.621318&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=APARTMENT) Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+Island%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=3486&latLong=0.259533%2C6.621318&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=APART_HOTEL) Cabins [](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+Island%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=3486&latLong=0.259533%2C6.621318&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=CABIN) Chalets [](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+Island%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=3486&latLong=0.259533%2C6.621318&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSao-Tome-Island-Private-Vacation-Homes.d3486-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSao-Tome-Island-Private-Vacation-Homes.d3486-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top São Tomé Island Hotel Reviews ![Omali São Tomé – Principe Collection](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a_y.jpg) ### Omali São Tomé – Principe Collection 10/10 Excellent "Lovely hotel, staff and location. Very close to airport as well Recommend highly" [](https://expedia.ca/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Porcelana Hotel](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/3a896a59_y.jpg) ### Porcelana Hotel 10/10 Excellent "Great value for price. Nice staff. Excellent breakfast." [](https://expedia.ca/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information) ![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44_y.jpg) ### Pestana São Tomé 10/10 Excellent "Wonderful stay, great staff, easy, relaxing delightful." [](https://expedia.ca/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) ![N Guembú Nature Resort](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/87364023_y.jpg) ### N Guembú Nature Resort 8/10 Good "The property requires some renovation works." [](https://expedia.ca/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information) ![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e_y.jpg) ### Hotel Kenito 10/10 Excellent "Exceptional" [](https://expedia.ca/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) ![CAMPISMO PRAIA GRANDE](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/03f83718_y.jpg) ### CAMPISMO PRAIA GRANDE 10/10 Excellent "A little piece of paradise on an amazing beach. " [](https://expedia.ca/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information) ## Find out more about São Tomé Island ## São Tomé Island Vacation Homes information | Number of reviews | 1 | | ----------------- | ---------------- | | Accommodation | 8 Vacation Homes | | Lowest Price | CA $203 | | Highest Price | CA $496 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [All Inclusive Resorts and in São Tomé and Príncipe ](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-All-Inclusive-Hotel.0-0-d156-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Hotel Hotels in São Tomé and Príncipe ](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Beach-Hotel.0-0-d156-tBeachHotel.Hotel-Filter-Destinations) - [Boutique Hotels in São Tomé and Príncipe ](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Boutique-Hotel.0-0-d156-tBoutiqueHotel.Hotel-Filter-Destinations) - [Business Hotels in São Tomé and Príncipe ](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Business-Hotel.0-0-d156-tBusinessHotel.Hotel-Filter-Destinations) - 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