Title: Book the Best BUSINESS Hotels in São Tomé Island in 2025 | Expedia.ca [São Tomé Island Travel Guide](https://expedia.ca/Sao-Tome-Island.dx3486)[Hotels in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Hotels.d3486.Travel-Guide-Hotels)[Vacation Rentals in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Vacation-Rentals.d3486.Travel-Guide-VacationRentals)[Flights to São Tomé Island](https://expedia.ca/Cheap-Flights-To-Sao-Tome-Island.d3486.Travel-Guide-Flights)[Things to do in São Tomé Island](https://expedia.ca/Things-To-Do-In-Sao-Tome-Island.d3486.Travel-Guide-Activities)[São Tomé Island Car Rentals](https://expedia.ca/Car-Rentals-In-Sao-Tome-Island.d3486.Car-Rental-Guide)[São Tomé Island Vacation Packages](https://expedia.ca/Sao-Tome-Island.d3486.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/6bd54b7b17061af058501372a92d6b86.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in São Tomé Island ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on São Tomé Island Business Hotels Tonight [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2025-10-07&endDate=2025-10-08&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2025-10-08&endDate=2025-10-09&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top São Tomé Island Business Hotels ![View from property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/741e11cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/1d47642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/fca34520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omali São Tomé – Principe Collection São Tomé 9.4/10 Exceptional (59) "The employees really make the property a superstar. " CA $279 CA $333 total includes taxes & fees Oct 18 - Oct 19 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Bungalow](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/e4d8c6e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/c5269885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/b8ac8133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic House | In-room dining](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/4670fd80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guest House Quinta Natural Trindade 10/10 Exceptional (1) CA $77 CA $111 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/0767273b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/46f82fa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/54c71534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room, 2 Single Beds](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/ed868ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Praia Accommodation São Tomé 7.2/10 Good (17) "Great place to stay " CA $177 CA $204 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/10340e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/1ba9ed4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, Partial Sea View](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/2db5e3ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/a0b55f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Kriola São Tomé 8.8/10 Excellent (3) "Loved the mermaids in the pool" CA $66 CA $129 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Sao-Tome-Hotels-Hotel-Kriola.h106989405.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6d211eb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/5dc4d7b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/863b6444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6e33456d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sweet Guest House São Tomé 8.8/10 Excellent (45) "Very clean and very well-maintained property" CA $70 CA $81 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Sweet-Guest-House.h12336226.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/3031ec18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/74d1540a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/d212df21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/29be8553.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Praia São Tomé 7.6/10 Good (17) "This place is way over priced for no wifi and linens that seemed like they were done in the River and dried on the rocks as most São Toméans must do Not for over $150 I’ve had better everything for $15 a night in west and central Africa And no matter how much you ask for help they just smile. D DO NOTHING" CA $224 CA $262 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information) ![Coffee shop](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5e2988d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5c6a7fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, City View](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/03eea49c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/fc496aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Central São Tomé 8.2/10 Very good (24) "This is an excellent centrally located well-kept hotel. Close to supermarket, restaurant and sites of interest in town, Friendly staff but language can be a bit of an issue" CA $78 CA $90 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/bab20d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/c4101405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/e6d4a2d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Twin Room](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/42171940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SH Boutique Hotel São Tomé 8.6/10 Excellent (10) "Staff were very accommodating " CA $110 CA $129 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-21&endDate=2025-10-22®ionId=3486&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top São Tomé Island Hotel Reviews ![Omali São Tomé – Principe Collection](//images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203_y.jpg) ### Omali São Tomé – Principe Collection 8/10 Good "It’s a great resort, with friendly staff who " [](https://expedia.ca/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Pestana São Tomé](//images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/ea6ea619_y.jpg) ### Pestana São Tomé 8/10 Good "Good choice in São Tomé city." [](https://expedia.ca/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in São Tomé Island with Expedia? > We're here to help you find a great business-friendly hotel when work takes you away from home. From free parking and WiFi to gyms and on-site restaurants, our stays come with the conveniences you'll need to get the job done. ### How can I find cheap business-friendly hotels in São Tomé Island? > Expedia can help you easily locate cheap business-friendly hotels in São Tomé Island. Simply go to our "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably, like included breakfast and free WiFi. You can also choose your budget and preferred star rating to keep costs under control. ### What is there to do in São Tomé Island near my business-friendly hotel? > São Tomé Island has enough sights and experiences to keep you entertained for weeks, starting with [Amelia Lagoon](https://www.expedia.ca/Amelia-Lagoon-Sao-Tome-Island.d759204977395933184.Vacation-Attraction). [São Nicolau Waterfall](https://www.expedia.ca/Sao-Nicolau-Waterfall-Sao-Tome-Island.d759203956928720896.Vacation-Attraction), [Pico São Tomé](https://www.expedia.ca/Pico-Sao-Tome-Sao-Tome-Island.d553248621532481757.Vacation-Attraction) and [Bom Sucesso Botanical Garden](https://www.expedia.ca/Bom-Sucesso-Botanical-Garden-Sao-Tome-Island.d759204479230058496.Vacation-Attraction) are other impressive attractions. If your business trip keeps you hanging around town a little longer, [Paroquia da Santissima Trindade](https://www.expedia.ca/Paroquia-Da-Santissima-Trindade-Sao-Tome-Island.d759205957222326272.Vacation-Attraction) and [Batepa Church](https://www.expedia.ca/Batepa-Church-Sao-Tome-Island.d759204152024014848.Vacation-Attraction) are great additions to your itinerary. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [All Inclusive Resorts and in São Tomé and Príncipe](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-All-Inclusive-Hotel.0-0-d156-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Hotel Hotels in São Tomé and Príncipe](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Beach-Hotel.0-0-d156-tBeachHotel.Hotel-Filter-Destinations) - [Boutique Hotels in São Tomé and Príncipe](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Boutique-Hotel.0-0-d156-tBoutiqueHotel.Hotel-Filter-Destinations) - 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