Title: Book the Best BUSINESS Hotels in São Tomé Island in 2025 | Expedia.ca [São Tomé Island Travel Guide](https://expedia.ca/Sao-Tome-Island.dx3486)[Hotels in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Hotels.d3486.Travel-Guide-Hotels)[Vacation Rentals in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Vacation-Rentals.d3486.Travel-Guide-VacationRentals)[Flights to São Tomé Island](https://expedia.ca/Cheap-Flights-To-Sao-Tome-Island.d3486.Travel-Guide-Flights)[Things to do in São Tomé Island](https://expedia.ca/Things-To-Do-In-Sao-Tome-Island.d3486.Travel-Guide-Activities)[São Tomé Island Car Rentals](https://expedia.ca/Car-Rentals-In-Sao-Tome-Island.d3486.Car-Rental-Guide)[São Tomé Island Vacation Packages](https://expedia.ca/Sao-Tome-Island.d3486.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/6bd54b7b17061af058501372a92d6b86.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in São Tomé Island ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on São Tomé Island Business Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2025-10-25&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top São Tomé Island Business Hotels ![View from property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/741e11cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/1d47642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/7d8ab7b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omali São Tomé – Principe Collection São Tomé 9.4/10 Exceptional (59) "The employees really make the property a superstar. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mona CA $278 CA $331 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/0767273b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room, 2 Single Beds](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/ed868ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, towels](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/184b1734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/54c71534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Praia Accommodation São Tomé 7.2/10 Good (17) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $177 CA $203 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/bab20d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/e6d4a2d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Twin Room](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/42171940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/c4101405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SH Boutique Hotel São Tomé 8.6/10 Excellent (10) "Staff were very accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Simon Peter CA $111 CA $130 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/10340e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/4d41d0ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, Partial Sea View](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/2db5e3ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/1ba9ed4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Kriola São Tomé 9.0/10 Wonderful (4) "Loved the mermaids in the pool" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Eduardo Jorge Bettencourt da CA $66 CA $128 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Sao-Tome-Hotels-Hotel-Kriola.h106989405.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/3031ec18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/29be8553.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/d212df21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/5242c321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Praia São Tomé 7.6/10 Good (17) "This place is way over priced for no wifi and linens that seemed like they were done in the River and dried on the rocks as most São Toméans must do Not for over $150 I’ve had better everything for $15 a night in west and central Africa And no matter how much you ask for help they just smile. D DO NOTHING" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tonya CA $226 CA $264 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information) ![Coffee shop](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5e2988d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/709afd60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5c6a7fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/fc496aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Central São Tomé 8.2/10 Very good (24) "Great value. Great location. Ok breakfast. Overall good value for money" ![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg) Elisabeth CA $78 CA $90 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information) ![Bungalow](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/e4d8c6e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/b8ac8133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic House | In-room dining](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/4670fd80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/2d9f01d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guest House Quinta Natural Trindade 10/10 Exceptional (1) CA $76 CA $110 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08®ionId=3486&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top São Tomé Island Hotel Reviews ![Omali São Tomé – Principe Collection](//images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203_y.jpg) ### Omali São Tomé – Principe Collection 8/10 Good "It’s a great resort, with friendly staff who " [](https://expedia.ca/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Pestana São Tomé](//images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/ea6ea619_y.jpg) ### Pestana São Tomé 8/10 Good "Good choice in São Tomé city." [](https://expedia.ca/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in São Tomé Island with Expedia? > We're here to help you find a great business-friendly hotel when work takes you away from home. From free parking and WiFi to gyms and on-site restaurants, our stays come with the conveniences you'll need to get the job done. ### How can I find cheap business-friendly hotels in São Tomé Island? > Expedia can help you easily locate cheap business-friendly hotels in São Tomé Island. Simply go to our "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably, like included breakfast and free WiFi. You can also choose your budget and preferred star rating to keep costs under control. ### What is there to do in São Tomé Island near my business-friendly hotel? > São Tomé Island has enough sights and experiences to keep you entertained for weeks, starting with [Amelia Lagoon](https://www.expedia.ca/Amelia-Lagoon-Sao-Tome-Island.d759204977395933184.Vacation-Attraction). [São Nicolau Waterfall](https://www.expedia.ca/Sao-Nicolau-Waterfall-Sao-Tome-Island.d759203956928720896.Vacation-Attraction), [Pico São Tomé](https://www.expedia.ca/Pico-Sao-Tome-Sao-Tome-Island.d553248621532481757.Vacation-Attraction) and [Bom Sucesso Botanical Garden](https://www.expedia.ca/Bom-Sucesso-Botanical-Garden-Sao-Tome-Island.d759204479230058496.Vacation-Attraction) are other impressive attractions. If your business trip keeps you hanging around town a little longer, [Paroquia da Santissima Trindade](https://www.expedia.ca/Paroquia-Da-Santissima-Trindade-Sao-Tome-Island.d759205957222326272.Vacation-Attraction) and [Batepa Church](https://www.expedia.ca/Batepa-Church-Sao-Tome-Island.d759204152024014848.Vacation-Attraction) are great additions to your itinerary. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [All Inclusive Resorts and in São Tomé and Príncipe](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-All-Inclusive-Hotel.0-0-d156-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Hotel Hotels in São Tomé and Príncipe](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Beach-Hotel.0-0-d156-tBeachHotel.Hotel-Filter-Destinations) - [Boutique Hotels in São Tomé and Príncipe](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Boutique-Hotel.0-0-d156-tBoutiqueHotel.Hotel-Filter-Destinations) - 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