Title: São Tomé Island Guest Houses from CA $104 | Expedia.ca [São Tomé Island Travel Guide](https://expedia.ca/Sao-Tome-Island.dx3486)[Hotels in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Hotels.d3486.Travel-Guide-Hotels)[Vacation Rentals in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Vacation-Rentals.d3486.Travel-Guide-VacationRentals)[Flights to São Tomé Island](https://expedia.ca/Cheap-Flights-To-Sao-Tome-Island.d3486.Travel-Guide-Flights)[São Tomé Island Car Rentals](https://expedia.ca/Car-Rentals-In-Sao-Tome-Island.d3486.Car-Rental-Guide)[São Tomé Island Vacation Packages](https://expedia.ca/Sao-Tome-Island.d3486.Destination-Travel-Guides) ![Nice place, good food... Quite difficult to reach, you need a good car...](https://images.trvl-media.com/place/553248621565299214/edf5448a-52b1-44ed-852d-bc5327dd1c36.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Fabrice Récalt ![](https://images.trvl-media.com/place/553248621565299214/edf5448a-52b1-44ed-852d-bc5327dd1c36.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 24 - Apr 26](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-05-22&endDate=2026-05-24&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for São Tomé Island guest houses ![On the beach](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/c133a29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/19a68080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/27e015d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/61594a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residêncial Tamarindos [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information) Guadalupe 8.6/10 Excellent (14 reviews) "Couldn’t have had better hosts Perfect location for great hikes and waterfalls Many thanks to Marlena and Betty who made our visit memorable x" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maria [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information) ![Bungalow](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/afa4170d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/b8ac8133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic House | Living area](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/6ff4185a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/a9f64453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guest House Quinta Natural [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) Trindade 10/10 Exceptional (1 review) [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/e065a121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/a9318aac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/27ea3314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Corner](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/fc229a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de Ferias [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information) São Tomé 8.8/10 Excellent (6 reviews) "I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member." ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Lars Roland CA $29 CA $104 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-06&endDate=2026-04-07®ionId=3486&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSao-Tome-Island-Guest-Houses.d3486-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSao-Tome-Island-Guest-Houses.d3486-aaGuestHouses.Travel-Guide-Accommodation) ## Top São Tomé Island Hotel Reviews ![Omali São Tomé – Principe Collection](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a_y.jpg) ### Omali São Tomé – Principe Collection 10/10 Excellent "Lovely hotel, staff and location. Very close to airport as well Recommend highly" [](https://expedia.ca/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Porcelana Hotel](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/3a896a59_y.jpg) ### Porcelana Hotel 10/10 Excellent "Great value for price. Nice staff. Excellent breakfast." [](https://expedia.ca/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information) ![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44_y.jpg) ### Pestana São Tomé 10/10 Excellent "Wonderful stay, great staff, easy, relaxing delightful." [](https://expedia.ca/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) ![N Guembú Nature Resort](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/87364023_y.jpg) ### N Guembú Nature Resort 8/10 Good "The property requires some renovation works." [](https://expedia.ca/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information) ![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e_y.jpg) ### Hotel Kenito 10/10 Excellent "Exceptional" [](https://expedia.ca/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) ![CAMPISMO PRAIA GRANDE](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/03f83718_y.jpg) ### CAMPISMO PRAIA GRANDE 10/10 Excellent "A little piece of paradise on an amazing beach. " [](https://expedia.ca/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information) ## Find out more about São Tomé Island ## São Tomé Island Guest Houses information | Number of reviews | 14 | | ----------------- | -------------- | | Accommodation | 9 Guest Houses | | Lowest Price | CA $104 | | Highest Price | CA $104 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [All Inclusive Resorts and in São Tomé and Príncipe ](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-All-Inclusive-Hotel.0-0-d156-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Hotel Hotels in São Tomé and Príncipe ](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Beach-Hotel.0-0-d156-tBeachHotel.Hotel-Filter-Destinations) - [Boutique Hotels in São Tomé and Príncipe ](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Boutique-Hotel.0-0-d156-tBoutiqueHotel.Hotel-Filter-Destinations) - [Business Hotels in São Tomé and Príncipe ](https://www.expedia.ca/Destinations-In-Sao-Tome-And-Principe-Business-Hotel.0-0-d156-tBusinessHotel.Hotel-Filter-Destinations) - 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