Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Santorini Island Business Hotels

See all 909 Hotels in Santorini Island
Hotel Thira

Hotel Thira

Fira, Santorini
1.0 out of 5.0
4.4 out of 5 (23 reviews)
Centrally located to the 'shopping mecca' If you want to shop up a storm then this is the hotel fro you! The family run hotel is in walking distance to the central shopping area as well as the area along the coast to view the most amazing sunsets. The simple wholesome breakfasts prepare you for a day of adventure ...try the local yoghurt ...
  2 Oct 2017

C$78

C$78
Romantic Spa Resort

Romantic Spa Resort

Agiou Athanasiou, Santorini
3.0 out of 5.0
4.0 out of 5 (26 reviews)
Ok hotel with pool.Ok hotel with pool. Slightly off the beaten track but walkable into town. Bring a torch if out in the dark. Staff very helpful.
  27 Apr 2017
Dream Island Hotel

Dream Island Hotel

Fira, Santorini
3.0 out of 5.0
4.8 out of 5 (57 reviews)
Brilliant family run hotel!The hotel is beautiful and over looks the east side of the sea. Started with the hotel picking us up from the airport and returning us (for no extra charge). The rooms are lovely and spacious, also very very clean! They provide pool towels by the pool. It's only a left turn out of the hotel and 4-5minute ...
  1 Oct 2017

C$132

C$132
Hotel Mathios Village

Hotel Mathios Village

Akrotiri Village, Santorini
3.0 out of 5.0
4.2 out of 5 (136 reviews)
A Hotel to return toWe had a wonderful stay at this hotel. The owner and his staff could not have been more friendly or helpful. Mama's cooking was good and their was a good selection of food. Everything was catered for, nothing was too much trouble.
  14 Sep 2017

C$84

C$84
9 Muses Santorini Resort

9 Muses Santorini Resort

Perivolos Emporiou, Santorini
5.0 out of 5.0
3.2 out of 5 (13 reviews)
Beautiful hotel with superb swimming poolHotel staff were pleasant, accommodating and very helpful in terms of sight seeing. 10-15min walk to the black beach also.
  3 Aug 2017
Abyssanto Suites & Spa

Abyssanto Suites & Spa

Imerovigli, Santorini
3.0 out of 5.0
4.6 out of 5 (38 reviews)
Amazing hotel and more extraordinary service!From the moment I got to the hotel, the staff was eager to help me plan the best days of my trip Inn santorini! My room was gorgeous and the view was unforgettable!! I would sdreonutiy recommend you stay here! Staff will make sure they accommodate you in the best way they can! Daily breakfast on ...
  13 Oct 2017

C$249

C$249
Acropole Sunrise

Acropole Sunrise

Agiou Pagratiou, Santorini
3.0 out of 5.0
4.4 out of 5 (11 reviews)
We enjoyed our stay at the Acropole Sunrise. The staff were first of all fantastic. The elevated position of the hotel allows you to see the sea from the hotel with the backdrop of the mountain behind you. The room included a fridge for those who would like to keep chilled drinks and food during ...
  20 May 2017
Acroterra Rosa

Acroterra Rosa

Akrotiri, Santorini
4.0 out of 5.0
4.9 out of 5 (32 reviews)
First class service and luxury. Superb staff, outstanding location, superior luxury all in one perfect location.
  29 Aug 2017
Aegean Plaza Hotel

Aegean Plaza Hotel

Kamari, Santorini
4.0 out of 5.0
3.8 out of 5 (21 reviews)
Atractive hotel and grounds close to bars etc Week long holiday with group of friends. Nice resort and beach better than anticipated. Many restaurants include beach bed and umbrella when you book lunch. Hotel pools are good but were more crowded towards end of our holiday. We booked a junior suite and were more than satisfied with space and ...
  12 Jul 2017
Map

Recently booked Santorini Island hotels

Dana Villas
4.0 out of 5.0
Last booking: 9 minutes ago
Dreams Luxury Suites
5.0 out of 5.0
Last booking: 1 hour ago
Mill Houses Elegant Suites
4.0 out of 5.0
Last booking: 2 hours ago
Santorini Princess Luxury Spa Hotel
5.0 out of 5.0
Last booking: 3 hours ago
Filotera Suites
4.0 out of 5.0
Last booking: 8 hours ago
Aqua Luxury Suites
4.0 out of 5.0
Last booking: 9 hours ago
Hotel Sunny Villas
4.0 out of 5.0
Last booking: 14 hours ago
Porto Fira Suites
4.0 out of 5.0
Last booking: 20 hours ago
Anny Studios Perissa Beach
3.0 out of 5.0
Last booking: 21 hours ago

Business Hotel Guide in Santorini Island

Work, play, and everything in between: Combine the best of every world with our selection of business hotels in Santorini Island. Inspired by the needs of the most discerning business traveler, these so-luxe spots provide everything you require to focus on your work and relax after a long afternoon of conference calls and face-to-face meetings.

You’ll get access to high-tech amenities, comfortable meeting rooms and a bevy of just-for-you services. Plus, when the day’s work is done, you can unwind in business class style with the upscale restaurants, in-room amenities, and top entertainment options.

Whether you’re searching for the sleekest executive business hotel in Santorini Island or want to find an unassuming spot near the office, our discounts and cheap deals will help you choose the perfect location for your unique needs. Browse our offerings to learn more about each business travel hotel in Santorini Island, and then pack your briefcase for a productive — and surprisingly fun — work trip.