Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Santorini Island Business Hotels

See all 965 Hotels in Santorini Island
Dream Island Hotel

Dream Island Hotel

Fira, Santorini
3.5 out of 5.0
Hotel Thira

Hotel Thira

Fira, Santorini
1.5 out of 5.0
Romantic Spa Resort

Romantic Spa Resort

Agiou Athanasiou, Santorini
3.5 out of 5.0
Hotel Mathios Village

Hotel Mathios Village

Akrotiri Village, Santorini
3.5 out of 5.0
9 Muses Santorini Resort

9 Muses Santorini Resort

Perivolos Emporiou, Santorini
5.0 out of 5.0
Abyssanto Suites & Spa

Abyssanto Suites & Spa

Imerovigli, Santorini
3.5 out of 5.0
Acropole Sunrise

Acropole Sunrise

Agiou Pagratiou, Santorini
3.5 out of 5.0
Acroterra Rosa

Acroterra Rosa

Akrotiri, Santorini
5.0 out of 5.0
Aegean Plaza Hotel

Aegean Plaza Hotel

Kamari, Santorini
4.0 out of 5.0
Map

Recently booked Santorini Island hotels

Ira Hotel & Spa
4.5 out of 5.0
Last booking: 1 minute ago
Astarte Suites
5.0 out of 5.0
Last booking: 41 minutes ago
Mill Houses Elegant Suites
4.5 out of 5.0
Last booking: 44 minutes ago
Kima Villa
3.0 out of 5.0
Last booking: 48 minutes ago
Santorini Princess Luxury Spa Hotel
5.0 out of 5.0
Last booking: 1 hour ago
Nikos Villas Hotel in Oia Santorini
3.5 out of 5.0
Last booking: 1 hour ago
Zacharakis Studios
2.5 out of 5.0
Last booking: 1 hour ago
Anthonas Apartments
3.5 out of 5.0
Last booking: 1 hour ago
Fava Eco Residences
4.0 out of 5.0
Last booking: 1 hour ago

Pocket Guide: Business Hotels in Santorini Island

Search for hotels in Santorini Island on Expedia. You can easily find your hotels in Santorini Island using one of the methods below:

  • View our selection of featured hotels in Santorini Island
  • Use the map to find hotels in the Santorini Island neighborhood you prefer
  • Use the filters to see hotels in a specific area of Santorini Island, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Santorini Island
  • Enter your travel dates to view the best deals on hotels in Santorini Island - while they last