Title: Book the Best Santo LUXURY Hotels - Upscale Hotels in Santo, TX | Expedia.ca [Hotels in Santo](https://expedia.ca/Santo-Hotels.d3000459245.Travel-Guide-Hotels)[Vacation Rentals in Santo](https://expedia.ca/Santo-Vacation-Rentals.d3000459245.Travel-Guide-VacationRentals)[Santo Car Rentals](https://expedia.ca/Car-Rentals-In-Santo.d3000459245.Car-Rental-Guide)[Santo Vacation Packages](https://expedia.ca/Santo.d3000459245.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Santo, TX ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santo Luxury Hotels Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=3000459245&startDate=2025-10-18&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=3000459245&startDate=2025-10-19&endDate=2025-10-20&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=3000459245&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=3000459245&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Santo Luxury Hotels ## Top Santo Hotel Reviews ![Holiday Inn Express Hotel & Suites Weatherford by IHG](//images.trvl-media.com/lodging/3000000/2370000/2369600/2369575/d90c3f76_y.jpg) ### Holiday Inn Express Hotel & Suites Weatherford by IHG 10/10 Excellent "very clean establishment, wonderfully kind staff, and an absolutely great breakfast with many options" [](https://expedia.ca/Weatherford-Hotels-Holiday-Inn-Express-Hotel-Suites-Weatherford.h2369575.Hotel-Information) ![Weatherford Heritage Inn](//images.trvl-media.com/lodging/1000000/10000/5500/5500/00553c68_y.jpg) ### Weatherford Heritage Inn 10/10 Excellent "Loved my stay. Comfortable bed, clean room. Only bad thing was the sheet/blanket on bed did not keep you warm" [](https://expedia.ca/Weatherford-Hotels-Weatherford-Heritage-Inn.h5500.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury getaway to Santo? > Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Santo offers. ### When can I expect good weather in Santo? > Planning for the weather is an important factor for making your trip to Santo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Santo is 38 inches. ### What's there to see and do in Santo? > Enjoy Santo and visit The Baker Hotel and Spa, Crazy Water Bath House & Spa, and Clark Gardens Botanical Park. 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