--- title: "Book The Best Hotels in Santo Antônio das Missões for 2026 from CA $48 - Fully Refundable Options - Expedia" description: "Book the best hotels in Santo Antônio das Missões in 2026. Compare room rates, hotel reviews and availability. Most hotels are fully refundable." canonical: "https://www.expedia.ca/Santo-Antonio-Das-Missoes-Hotels.d553248634664620111.Travel-Guide-Hotels" language: en-CA market: CA currency: CAD prices_as_of: 2026-11-14T09:47:51Z --- Plan your trip - [Santo Antônio das Missões Travel Guide](https://www.expedia.ca/Santo-Antonio-Das-Missoes.dx553248634664620111) - [Flights to Santo Antônio das Missões](https://www.expedia.ca/Cheap-Flights-To-Santo-Antonio-Das-Missoes.d553248634664620111.Travel-Guide-Flights) - [Car Rentals in Santo Antônio das Missões](https://www.expedia.ca/Car-Rentals-In-Santo-Antonio-Das-Missoes.d553248634664620111.Car-Rental-Guide) - [Santo Antônio das Missões Vacation Packages](https://www.expedia.ca/Santo-Antonio-Das-Missoes.d553248634664620111.Destination-Travel-Guides) - [Vacation Rentals in Santo Antônio das Missões](https://www.expedia.ca/Santo-Antonio-Das-Missoes-Vacation-Rentals.d553248634664620111.Travel-Guide-VacationRentals) # Find hotels in Santo Antônio das Missões from CA $48 ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santo Antônio das Missões [Pet friendly](https://www.expedia.ca/Hotel-Search?destination=Santo%20Antônio%20das%20Missões,%20Rio%20Grande%20do%20Sul,%20Brazil®ionId=553248634664620111&latLong=-28.51179,-55.229005&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&amenities=PETS) [Pool](https://www.expedia.ca/Hotel-Search?destination=Santo%20Antônio%20das%20Missões,%20Rio%20Grande%20do%20Sul,%20Brazil®ionId=553248634664620111&latLong=-28.51179,-55.229005&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&amenities=POOL) [Apart­ment](https://www.expedia.ca/Hotel-Search?destination=Santo%20Antônio%20das%20Missões,%20Rio%20Grande%20do%20Sul,%20Brazil®ionId=553248634664620111&latLong=-28.51179,-55.229005&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=APARTMENT) [Family friendly](https://www.expedia.ca/Hotel-Search?destination=Santo%20Antônio%20das%20Missões,%20Rio%20Grande%20do%20Sul,%20Brazil®ionId=553248634664620111&latLong=-28.51179,-55.229005&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&travelerType=family%5Ffriendly) [Condo](https://www.expedia.ca/Hotel-Search?destination=Santo%20Antônio%20das%20Missões,%20Rio%20Grande%20do%20Sul,%20Brazil®ionId=553248634664620111&latLong=-28.51179,-55.229005&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=CONDO) [Waterpark](https://www.expedia.ca/Hotel-Search?destination=Santo%20Antônio%20das%20Missões,%20Rio%20Grande%20do%20Sul,%20Brazil®ionId=553248634664620111&latLong=-28.51179,-55.229005&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&amenities=WATER%5FPARK) ## Check prices for these dates [Check prices for these dates, December 14–15, 2026](https://www.expedia.ca/Hotel-Search?regionId=553248634664620111&startDate=2026-12-14&endDate=2026-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) [View in a map](https://www.expedia.ca/Hotel-Search?regionId=553248634664620111&stayLength=1&daysInFuture=30&pwaOverlay=map) ## Our top choices for Santo Antônio das Missões hotels ### [1\. Hotel El Caminito](https://www.expedia.ca/Sao-Borja-Hotels-Hotel-El-Caminito.h120547179.Hotel-Information) ![A colorful building with multiple sections, each painted in different bright colors.](https://images.trvl-media.com/lodging/121000000/120550000/120547200/120547179/64f6129c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: São Borja - Guest rating: 8.6/10 (Excellent, 29 reviews) - Price: CA $95, CA $100 total, includes taxes & fees, Nov 18 - Nov 19 - Review: Achei precária a higienização, pois nosso banheiro tinha calo na parede, na área do chuveiro. Os lençóis estavam amassados, como se já tivessem sido usados. Quero acreditar na recepcionista, que afirmou que era resultado lavagem, por isso ficaram assim., by Juceanita M ### [2\. Sitio Preserva](https://www.expedia.ca/Sao-Borja-Hotels-Sitio-Preserva.h75209962.Hotel-Information) ![A room with red plastic chairs and tables, colorful drapes, and a striped balloon decoration.](https://images.trvl-media.com/lodging/76000000/75210000/75210000/75209962/f51989a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: São Borja - Guest rating: 2/10 (1 review) - Price: CA $49, CA $51 total, includes taxes & fees, Dec 13 - Dec 14 - Review: Sofri um golpe ao tentar me hospedar nesse lugar. Confirmaram a reserva pelo site do hotels.com, mas quando cheguei no local disseram que não havia vagas. Contestei a cobrança via operadora do cartão de crédito, pois o atendimento do site desligou na minha cara, o profissional Mahmud me fez esperar muito tempo e não resolveu meu problema., by Vinícius Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://www.expedia.ca/Hotel-Search?startDate=2026-11-28&endDate=2026-11-29®ionId=553248634664620111&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Frequently Asked Questions ### What is the best area to stay in Santo Antônio Das Missões? The best area to stay in Santo Antônio Das Missões is generally in the town centre, as it offers the most convenient access to local amenities and the main square. The town centre, particularly around Praça Matriz (the main square), is the hub of activity. Here, you'll find the primary church, local shops, and a selection of eateries. The streets are laid out in a grid pattern, making it easy to navigate on foot. Most of the town's services are concentrated within a few blocks of the square. For travellers interested in experiencing local life and having everything within walking distance, staying in the town centre is ideal. You'll be close to the local markets, where you can find regional products, and the main church, which is a focal point for the community. ### When is the best time to go to Santo Antônio Das Missões? The best time to visit Santo Antônio Das Missões is during the drier, cooler months between April and September. This period avoids the intense heat and humidity of the summer, as well as the heavier rainfall. You'll find the weather more comfortable for exploring the area's natural beauty and historical sites. For those interested in cultural events, local festivals often take place during the cooler months, offering a glimpse into the region's traditions. Couples looking for a relaxing getaway will appreciate the pleasant weather for leisurely strolls and outdoor activities without the discomfort of high temperatures. It's a great time for enjoying the scenic landscapes and the more tranquil pace of life. Families travelling with children will also find this period ideal. ### Can I cancel my hotel reservation on Expedia? You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santo Antônio das Missões. ### How much is the nightly rate at a Santo Antônio das Missões hotel? Prices for hotels in Santo Antônio das Missões often vary, but you can find a great deal from CA $48 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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