Santiago Vacation Packages
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Your Santiago Vacation
Enjoy the urban city of Santiago with a tailor-made Santiago vacation package and immerse yourself in all it can offer. From its rich history and cultural experiences to its lively atmosphere, prepare to fall for the unique charms of this vibrant destination. Parque Acuatico Italia Guadalupe Panama, Catedral of Santiago Apostol and Plaza Banconal are just some of the sights you'll want to see during your trip to Santiago. A few quick clicks is all it takes to put together the perfect Santiago vacation on Expedia.
Top Santiago Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City
San Francisco
CA $1,198
per person
Nov 8 - Nov 14
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
8.6/10 Excellent! (1,719 reviews)
The property is totally different like the pictures and rating on line the rooms are very old bathroom fixtures leaking no A/C on the commons areas apparently years ago go this hotel was one of the best ones but not anymore staff unprofessional people I really have a very bad experience on this hotel highly not recommended for staying and the prices are similar like RIU Hilton Marriott unfortunately in my trip those hotels wasn't booked
Reviewed on Sep 30, 2026
Central Hotel Panama Casco Viejo
Casco Viejo
CA $1,861
per person
Nov 8 - Nov 14
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
9/10 Wonderful! (1,007 reviews)
Beautiful hotel, amazing food, and even better staff. Everyone went above and beyond to genuinely make us feel welcome, and you could tell they took a lot of pride in the hotel and their roles.
A special thank you to Jose Luis, Victor, Felix, and the rest of the restaurant staff. They were excellent and a big part of what made our stay so enjoyable.
We will definitely be staying at Central Hotel again when we’re back in Panama next year. Highly recommend!
Reviewed on Sep 29, 2026
Riande Aeropuerto Hotel & Casino
Tocumen Airport
CA $1,237
per person
Nov 8 - Nov 14
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
8.6/10 Excellent! (1,820 reviews)
Some things were unclear during check in .. However, the overall experience was ok I guess.
Reviewed on Sep 30, 2026
Yoo by Wynwood House
Calidonia
CA $2,804
per person
Dec 23 - Dec 30
found 13 hours ago
Roundtrip flight included
Toronto (YYZ) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.
Reviewed on Jul 26, 2025
Ready to book your vacation to Santiago?
Santiago Hotel Deals
Hotel Gran David
Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
CA $109
CA $119 total
Oct 3 - Oct 4
includes taxes & fees
HOTEL CORPORATIVO PLAZA COROTÚ
Carr. Panamericana Santiago Provincia de Veraguas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santiago attractions
Escuela Normal Juan Demostenes Arosemena
9.2/10 (9 reviews)
Explore the campus of Escuela Normal Juan Demostenes Arosemena, during your trip to Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.
Catedral of Santiago Apostol
8.8/10 (13 reviews)
Find out about the history of Santiago when you take a trip to Catedral of Santiago Apostol. Amble around the area's lakeside or visit its cathedral.
Omar Torrijos Herrera Stadium
8.4/10 (9 reviews)
Catch an event at Omar Torrijos Herrera Stadium during your trip to Santiago. Amble around the area's lakeside or visit its cathedral.
Plaza Banconal
8.6/10 (12 reviews)
You can find the perfect gifts to bring home at Plaza Banconal during your stay in Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.
Frequently asked questions
How much does a Santiago vacation package cost?
You can pick up a vacation package to this top destination from CA $1,198 on Expedia. But how much your vacation to Santiago costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Santiago?
September, October and November are great times to look for cheap Santiago vacation packages. Travelling in less busy periods means you can usually find lower prices on accommodations and flights.
How many days is enough for Santiago?
The ideal duration for your Santiago vacation depends on what you'd like to do and see. Generally, a few days to a week will give you enough time to check out all the main sights and discover some hidden treasures along the way.
Is it worth booking a vacation package to Santiago?
Well known for its shopping, culture and a host of other highlights, you can be certain Santiago is a good vacation destination. Some of the most popular attractions to stick on your to-do list? Visit Parque Acuatico Italia Guadalupe Panama and Escuela Normal Juan Demostenes Arosemena during your Santiago vacation.
How to find the best Santiago package deals?
Finding a cheap Santiago package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a couple of filters and browse what's available. You can personalize your search by "Amenities," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most pocket-friendly Santiago package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider travelling on a weekday, when prices are usually lower.
Is it cheaper to book a Santiago vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll generally snag a better deal than booking each component individually. And you'll still get the freedom to create a customized Santiago vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Santiago?
If you're planning a spur-of-the-moment Santiago getaway, check out our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can find sensational deals on your flights and hotels by booking well in advance.
How to plan a trip to Santiago?
- Choose when to go: Check your schedule and get packing. Your preferred season and the type of activities on offer will also help you decide when to escape to Santiago.
- Calculate your budget: Ensure you have enough money to cover everything from food and transportation to activities and flights. Your hotel will likely be the largest expense during your trip to Santiago.
- Set the duration of your trip: Start by compiling a list of the activities and attractions you want to get to in Santiago. Then, estimate how long you'll need for each, along with any travel time.
- Bundle your flights and hotel: Epic destination, check. Length of stay, check. All that's left is to choose a Santiago vacation package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
