Santiago Vacation Packages

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Your Santiago Vacation

Enjoy the urban city of Santiago with a tailor-made Santiago vacation package and immerse yourself in all it can offer. From its rich history and cultural experiences to its lively atmosphere, prepare to fall for the unique charms of this vibrant destination. Parque Acuatico Italia Guadalupe Panama, Catedral of Santiago Apostol and Plaza Banconal are just some of the sights you'll want to see during your trip to Santiago. A few quick clicks is all it takes to put together the perfect Santiago vacation on Expedia.

Top Santiago Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Aug 16 - Aug 23
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to Panama City (PTY)
9/10 Wonderful! (932 reviews)
Love the location and the restaurant inside the hotel was phenomenal.

Reviewed on Jul. 11, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
per person
Sep 15 - Sep 22
found 14 hours ago
Roundtrip flight included
Toronto (YYZ) to Panama City (PTY)
No reviews
La Coralina Island House

La Coralina Island House

3.5 out of 5
Save 100% on your flight
per person
Sep 15 - Sep 22
found 14 hours ago
Roundtrip flight included
Toronto (YYZ) to Panama City (PTY)
9.4/10 Exceptional! (82 reviews)
Wow! This resort is absolutely amazing! Bekar went above and beyond for us! He even brought in a TV to the lobby so we could watch the NHL playoff game! Food is 10/10 as well. We will definitely go back!

Reviewed on May 18, 2025

The Sands by Wynwood House

The Sands by Wynwood House

2 out of 5
Calidonia
Save 100% on your flight
per person
Oct 9 - Oct 12
found 12 hours ago
Roundtrip flight included
Montreal (YUL) to Panama City (PTY)
No reviews
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
Sep 22 - Sep 29
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Panama City (PTY)
8.8/10 Excellent! (143 reviews)
Good place for relax and enjoy good vacations with the family

Reviewed on Apr. 6, 2025

Ready to book your vacation to Santiago?

 

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Santiago Hotel Deals

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is CA $96 per night from Jul 17 to Jul 18
CA $96
CA $106 total
Jul 17 - Jul 18
includes taxes & fees
8.4/10 Very Good! (310 reviews)
"I did not like the stale smell in the room when I entered it and the smell was persistent."

Reviewed on Jun. 12, 2025

Hotel Gran David
HOTEL PLAZA COROTÚ

HOTEL PLAZA COROTÚ

2 out of 5
Carr. Panamericana, Santiago, Provincia de Veraguas
9/10 Wonderful! (19 reviews)
"They will wash and laundry for a reasonable fee."

Reviewed on Feb. 24, 2025

Get rates
HOTEL PLAZA COROTÚ
Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

2 out of 5
Santiago
Get rates
Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone
See all 12 properties in Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Discover the most popular places to visit in Santiago

Escuela Normal Juan Demostenes Arosemena

Explore the campus of Escuela Normal Juan Demostenes Arosemena, during your trip to Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.

Escuela Normal Juan Demostenes Arosemena

Frequently asked questions

How much does a Santiago vacation package cost?
You can pick up a vacation package to this top destination from CA $1,670 on Expedia. But how much your vacation to Santiago costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Santiago?
September, October and November are great times to look for cheap Santiago vacation packages. Travelling in less busy periods means you can usually find lower prices on accommodations and flights.
How many days is enough for Santiago?
The ideal duration for your Santiago vacation depends on what you'd like to do and see. Generally, a few days to a week will give you enough time to check out all the main sights and discover some hidden treasures along the way.
Is it worth booking a vacation package to Santiago?
Well known for its shopping, culture and a host of other highlights, you can be certain Santiago is a good vacation destination. Some of the most popular attractions to stick on your to-do list? Visit Parque Acuatico Italia Guadalupe Panama and Escuela Normal Juan Demostenes Arosemena during your Santiago vacation.
How to find the best Santiago package deals?
Finding a cheap Santiago package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a couple of filters and browse what's available. You can personalize your search by "Amenities," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most pocket-friendly Santiago package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider travelling on a weekday, when prices are usually lower.
Is it cheaper to book a Santiago vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll generally snag a better deal than booking each component individually. And you'll still get the freedom to create a customized Santiago vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Santiago?
If you're planning a spur-of-the-moment Santiago getaway, check out our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can find sensational deals on your flights and hotels by booking well in advance.
How to plan a trip to Santiago?

  1. Choose when to go: Check your schedule and get packing. Your preferred season and the type of activities on offer will also help you decide when to escape to Santiago.
  2. Calculate your budget: Ensure you have enough money to cover everything from food and transportation to activities and flights. Your hotel will likely be the largest expense during your trip to Santiago.
  3. Set the duration of your trip: Start by compiling a list of the activities and attractions you want to get to in Santiago. Then, estimate how long you'll need for each, along with any travel time.
  4. Bundle your flights and hotel: Epic destination, check. Length of stay, check. All that's left is to choose a Santiago vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.