Title: Visit Santiago Sur: Best of Santiago Sur Tourism | Expedia Travel Guide - Expedia.ca [Hotels in Santiago Sur](https://expedia.ca/Santiago-Sur-Hotels.d829297894222729216.Travel-Guide-Hotels)[Vacation Rentals in Santiago Sur](https://expedia.ca/Santiago-Sur-Vacation-Rentals.d829297894222729216.Travel-Guide-VacationRentals)[Santiago Sur Car Rentals](https://expedia.ca/Car-Rentals-In-Santiago-Sur.d829297894222729216.Car-Rental-Guide)[Santiago Sur Vacation Packages](https://expedia.ca/Santiago-Sur.d829297894222729216.Destination-Travel-Guides) # Santiago Sur ## Travel Guide ## Visit Santiago Sur - Santiago Sur Hotel Deals - Vacation Rentals in Santiago Sur ![Cabañas Palma Real](https://images.trvl-media.com/lodging/111000000/110250000/110247200/110247155/d9e9c65b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cabañas Palma Real Las Colomas, Santiago Sur via principal Santiago Sur Provincia de Veraguas CA $81 CA $103 total Dec 28 - Dec 29 includes taxes & fees Stay at this cabin in Santiago Sur. Enjoy free WiFi, free parking, and a garden. [](https://expedia.ca/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=110247155&PinnedHotelID=110247155&HadPinnedHotel=true®ionId=829297894222729216) ![Hotel Mykonos Panama](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/cdb98b1d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Mykonos Panama Panamerican Highway Nuevo Santiago Veraguas CA $116 CA $128 total Dec 25 - Dec 26 includes taxes & fees Book a stay at this spa hotel in Nuevo Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Plaza Banconal and Omar Torrijos Herrera ... 8.8/10 Excellent! (539 reviews) Everything was great! Reviewed on Dec 17, 2025 [](https://expedia.ca/Hotel-Search?startDate=25%2F12%2F2025&endDate=26%2F12%2F2025&selected=5270392&PinnedHotelID=5270392&HadPinnedHotel=true®ionId=829297894222729216) ![Hotel Gran David](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/5966cf9c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Gran David Vía Interamericana Santiago Veraguas CA $90 CA $101 total Dec 31 - Jan 1, 2026 includes taxes & fees Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ... 8.4/10 Very Good! (353 reviews) Everything was very good Reviewed on Nov 22, 2025 [](https://expedia.ca/Hotel-Search?startDate=31%2F12%2F2025&endDate=01%2F01%2F2026&selected=12003378&PinnedHotelID=12003378&HadPinnedHotel=true®ionId=829297894222729216) [See all 54 properties in Santiago Sur](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=829297894222729216) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Cabañas Palma Real](https://images.trvl-media.com/lodging/111000000/110250000/110247200/110247155/d9e9c65b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cabañas Palma Real Las Colomas, Santiago Sur via principal Santiago Sur Provincia de Veraguas Stay at this cabin in Santiago Sur. Enjoy free WiFi, free parking, and a garden. [](https://expedia.ca/Santiago-Sur-Hotels-Cabanas-Palma-Real.h110247155.Hotel-Information) ![Cozy Villa with private pool, 5 min walk to a secluded beach, family friendly](https://images.trvl-media.com/lodging/97000000/96790000/96789700/96789678/4b321a7d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cozy Villa with private pool, 5 min walk to a secluded beach, family friendly Santa Catalina Provincia de Veraguas Stay at this villa in Santa Catalina. Enjoy free WiFi, private pools, and a garden. Popular attractions Lagartero Beach and Estero Beach are located nearby. 9.8/10 Exceptional! (10 reviews) Destination Paradise was exactly what we were looking for!Dawn and Alie were amazing hosts, responding quickly to any requests.It was fully equipped making it a perfect choice for a relaxing 10 day vacation.Pool was refreshing. Birds incredible!We definitely plan to return soon. Reviewed on Nov 30, 2025 [](https://expedia.ca/Hicaco-Hotels-Cozy-Villa-With-Private-Pool.h96789678.Hotel-Information) ![Kooteja Santa Catalina KAÏSA](https://images.trvl-media.com/lodging/114000000/113050000/113049400/113049390/c002e6d0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Kooteja Santa Catalina KAÏSA lagartero, panama Hicaco Provincia de Veraguas Stay at this cabin in Hicaco. Enjoy free WiFi, free parking, and air conditioning. Popular attractions Lagartero Beach and Estero Beach are located nearby. 8/10 Very Good! (1 review) The system to get in the cabin is pretty clever, and the place looked nice. Yet, I would have appreciated instructions on where to leave the money and also if the grass around the cabin was lower or cut. Reviewed on May 2, 2025 [](https://expedia.ca/Hicaco-Hotels-Kooteja-Santa-Catalina-KAISA.h113049390.Hotel-Information) [See all properties in Santiago Sur](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=829297894222729216&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santiago Sur hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297894222729216&startDate=2025-12-24&endDate=2025-12-25)[Dec 24 - Dec 25](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297894222729216&startDate=2025-12-24&endDate=2025-12-25) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297894222729216&startDate=2025-12-25&endDate=2025-12-26)[Dec 25 - Dec 26](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297894222729216&startDate=2025-12-25&endDate=2025-12-26) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297894222729216&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)[Dec 26 - Dec 28](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297894222729216&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297894222729216&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026)[Jan 2 - Jan 4](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297894222729216&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [Atalaya Hotels ](https://www.expedia.ca/Atalaya-Hotels.d3000007476.Travel-Guide-Hotels) - [Veraguas Hotels ](https://www.expedia.ca/Destinations-In-Veraguas.d6246233.Hotel-Destinations) - [El Marañon Hotels ](https://www.expedia.ca/El-Maranon-Hotels.d829298061130866688.Travel-Guide-Hotels) - [Isla Cebaco Hotels ](https://www.expedia.ca/Isla-Cebaco-Hotels.d553248633876799007.Travel-Guide-Hotels) - 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