Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Santiago Apartment Hotel

See all 617 Hotels in Santiago
Altura Suites

Altura Suites

Merced 562, 317 B, Santiago
3.0 out of 5.0
4.1 out of 5 (778 reviews)
Cheap and cheerful and centralWonderful location in the center of the old city, walked everywhere. First impression was disappointing, entrance, reception, hallway but the rooms (4) were lovely and in good order though not pristine, everything clean and neat. Great to have a suite with a kitchen and a big grocery store just beneath ...
  8 Oct 2017

C$57

C$57
Acero Apartment

Acero Apartment

San Francisco 335, Santiago
3.0 out of 5.0
4.1 out of 5 (102 reviews)
Confortable, Close to City Center,Confortable, Close to City Center, Staff available to answer questions, Fast Internet Available.
  12 Oct 2017

C$51

C$51
Chileapart.com

Chileapart.com

Merced 562, Of. 819-A, Santiago
3.0 out of 5.0
4.1 out of 5 (164 reviews)
Perfect location for a Great StayTen day stay in Santiago, before heading south. First thing is that the hotel staff are very friendly and helpful. The rooms are laid out well. There is even a fairly large well stocked grocery store located on the street level of the building. Being in the heart of El Centro district, everything ...
  9 Mar 2017

C$65

C$65
Lastarria Santiago Suite

Lastarria Santiago Suite

Padre Luis de Valdivia 339, Santiago
3.0 out of 5.0
4.3 out of 5 (63 reviews)
Great apartment close to lots of activitiesGreat apartment, spacious with great wifi, walking distance to lots of amenities, parks & museums. Located in a trendy spot with lots of great restaurants nearby.
  3 Nov 2017

C$76

C$76
Bellavista Apartments

Bellavista Apartments

Dardignac 28, Santiago
3.5 out of 5.0
4.3 out of 5 (108 reviews)
Stay to recover from jetlag This Aparthotel met our needs perfectly. It was well situated for saleable restaurants and market for self catering. Also good metro and bus links to the rest of Santiago. We will stay there again in 5 weeks on the way home.
  5 Oct 2017

C$84

C$84
Pinos Azules

Pinos Azules

Obispo Orrego, 52, Santiago
2.5 out of 5.0
3.9 out of 5 (17 reviews)
Alto Lyon Departamentos

Alto Lyon Departamentos

Nueva de Lyon 170, Santiago
3.5 out of 5.0
3.9 out of 5 (17 reviews)
Excellent all roundExcellent location, great staff. Highly recommend.
  5 Sep 2016
La Casa Roja

La Casa Roja

Agustinas 2113, Santiago
2.0 out of 5.0
3.6 out of 5 (28 reviews)
Great private room and fun crowd!This was a perfect first spot on my trip to Chile. I was travelling solo and wanted to find somewhere with lots of energy and Casa Roja has it! People are partying all night so keep that in mind if it's not what you want. I stayed in a private room with a private bathroom and both were really big, ...
  21 Feb 2016

C$59

C$59
San Ignacio Suite Apartments

San Ignacio Suite Apartments

Paseo Huerfanos 547, Santiago
3.0 out of 5.0
4.1 out of 5 (39 reviews)
HugeNot a hotel as such but comfy and well situated in the centre close all sites
  27 Apr 2015

C$92

C$92
VO Bellas Artes Apartment

VO Bellas Artes Apartment

Santo Domingo 664 oficina 607-A, Santiago
3.5 out of 5.0
3.6 out of 5 (140 reviews)
Great bargainReally enjoyed my stay, good location, nice secure building, all good!
  27 Aug 2015

C$98

C$98
Map

Recently booked Santiago hotels

Rukaza Lastarria
3.0 out of 5.0
Last booking: 24 minutes ago
Holiday Inn Santiago - Airport Terminal
3.5 out of 5.0
Last booking: 28 minutes ago
NH Collection Plaza Santiago
4.0 out of 5.0
Last booking: 2 hours ago
Hotel Manquehue Aeropuerto
3.5 out of 5.0
Last booking: 3 hours ago
Hilton Garden Inn Santiago Airport
3.5 out of 5.0
Last booking: 5 hours ago
Hotel Cumbres Lastarria
4.0 out of 5.0
Last booking: 5 hours ago
Hotel Plaza San Francisco
4.0 out of 5.0
Last booking: 6 hours ago
Mercure Santiago Centro
3.5 out of 5.0
Last booking: 6 hours ago
Bellavista Apartments
3.5 out of 5.0
Last booking: 6 hours ago

Pocket Guide: Apartment Hotel in Santiago

Search for hotels in Santiago on Expedia. You can easily find your hotels in Santiago using one of the methods below:

  • View our selection of featured hotels in Santiago
  • Use the map to find hotels in the Santiago neighborhood you prefer
  • Use the filters to see hotels in a specific area of Santiago, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Santiago
  • Enter your travel dates to view the best deals on hotels in Santiago - while they last