Title: Santiago Este Vacation Rentals : Short-Term Rentals for 2025 | Expedia.ca [Santiago Este Travel Guide](https://expedia.ca/Santiago-Este.dx829297293743108096)[Hotels in Santiago Este](https://expedia.ca/Santiago-Este-Hotels.d829297293743108096.Travel-Guide-Hotels)[Santiago Este Car Rentals](https://expedia.ca/Car-Rentals-In-Santiago-Este.d829297293743108096.Car-Rental-Guide)[Santiago Este Vacation Packages](https://expedia.ca/Santiago-Este.d829297293743108096.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Santiago Este Vacation Rentals - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=829297293743108096&startDate=2025-11-21&endDate=2025-11-23&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=829297293743108096&startDate=2026-01-02&endDate=2026-01-04&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=829297293743108096&startDate=2026-01-30&endDate=2026-02-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=829297293743108096&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Vacation Rentals in Santiago Este ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantiago-Este-Vacation-Rentals.d829297293743108096.Travel-Guide-VacationRentals)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantiago-Este-Vacation-Rentals.d829297293743108096.Travel-Guide-VacationRentals) ## Top Santiago Este Hotel Reviews ![Hotel Mykonos Panama](//images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/cdb98b1d_y.jpg) ### Hotel Mykonos Panama 10/10 Excellent "Great room, great food and great price" [](https://expedia.ca/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information) ![HOTEL VISTA LAGO](//images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/4e3dd11f_y.jpg) ### HOTEL VISTA LAGO 10/10 Excellent "El lugar es muy tranquilo, las habitaciones cómodas y la comida muy buena " [](https://expedia.ca/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information) ![Hotel Gran David](//images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/5966cf9c_y.jpg) ### Hotel Gran David 10/10 Excellent "Clean and cozy room. Nice hotel with beautiful interior gardens which make you feel like being in one big hacienda. Excellent and friendly staff ." [](https://expedia.ca/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information) ![Hotel Galería](//images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/7a530baa_y.jpg) ### Hotel Galería 10/10 Excellent "Clean room and great breakfast. My kids enjoyed the pool." [](https://expedia.ca/Santiago-Hotels-Hotel-Galeria.h27570722.Hotel-Information) ![HOTEL PLAZA COROTÚ](//images.trvl-media.com/lodging/112000000/111280000/111276700/111276682/1a9e698d_y.jpg) ### HOTEL PLAZA COROTÚ 10/10 Excellent "They will wash and laundry for a reasonable fee." [](https://expedia.ca/Santiago-Hotels-HOTEL-PLAZA-COROTU.h111276682.Hotel-Information) ## Find out more about Santiago Este **Everything you need to know about** **Santiago Este** **vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santiago Este vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santiago Este vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.  **Santiago Este vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Santiago Este. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santiago Este vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santiago Este vacation rentals we have selected for you start as low as per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Santiago Este rentals** At Expedia, we put the best Santiago Este vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top Santiago Este rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santiago Este vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santiago Este. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - [Vancouver Vacation Rentals](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals](https://www.expedia.ca/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Tofino Vacation Rentals](https://www.expedia.ca/Tofino-Vacation-Rentals.d6094955.Travel-Guide-VacationRentals) - [Calgary Vacation Rentals](https://www.expedia.ca/Calgary-Vacation-Rentals.d178245.Travel-Guide-VacationRentals) - [Costa Rica Vacation Rentals](https://www.expedia.ca/Destinations-In-Costa-Rica.d42.Vacation-Rental-Destinations) - [Vancouver Island Vacation Rentals](https://www.expedia.ca/Vancouver-Island-Vacation-Rentals.d6058387.Travel-Guide-VacationRentals) - [Puerto Vallarta Vacation Rentals](https://www.expedia.ca/Puerto-Vallarta-Vacation-Rentals.d180016.Travel-Guide-VacationRentals) - [Hawaii Vacation Rentals](https://www.expedia.ca/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Toronto Vacation Rentals](https://www.expedia.ca/Toronto-Vacation-Rentals.d178314.Travel-Guide-VacationRentals) - [Banff Vacation Rentals](https://www.expedia.ca/Banff-Vacation-Rentals.d10550.Travel-Guide-VacationRentals) - [Penticton Vacation Rentals](https://www.expedia.ca/Penticton-Vacation-Rentals.d4135.Travel-Guide-VacationRentals) - [Osoyoos Vacation Rentals](https://www.expedia.ca/Osoyoos-Vacation-Rentals.d181782.Travel-Guide-VacationRentals) - [Mont Tremblant Vacation Rentals](https://www.expedia.ca/Mont-Tremblant-Vacation-Rentals.d55374.Travel-Guide-VacationRentals) - [Big White Ski Resort Vacation Rentals](https://www.expedia.ca/Big-White-Ski-Resort-Vacation-Rentals.d6058319.Travel-Guide-VacationRentals) - [Ontario Vacation Rentals](https://www.expedia.ca/Destinations-In-Ontario.d11178.Vacation-Rental-Destinations) - [British Columbia Vacation Rentals](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations) - [Prince Edward Island Vacation Rentals](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations) - [Québec Vacation Rentals](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals) ## Frequently asked questions ### Can I find vacation rentals in Santiago Este? > Yes, we offer vacation rentals near the most popular sights in Santiago Este, or you can go with a more secluded option if you want a relaxing place to stay. ### What are some of the best vacation home rentals that Santiago Este has to offer? > [Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone](https://www.expedia.ca/Santiago-Hotels-Charming-2-Bedroom-House-In-Amazing-Santiago-With-AC.h109329235.Hotel-Information): This vacation home rental outside of Santiago Este has air-conditioning and a Smart TV to help you feel perfectly comfortable in your new surroundings. Kitchen amenities like a stovetop and a microwave can make your vacation run smoothly. ### What’s there to see and do in Santiago Este? > While exploring the area, visit family-friendly sights like Parque Acuatico Italia Guadalupe Panama, or get outside and enjoy nature at Sarigua National Park. Escuela Normal Juan Demostenes Arosemena and Stella Sierra Regional Museum are a couple of places you'll find in the larger area. ### What’s a vacation rental in Santiago Este like? > Vacation rentals are privately owned accommodations you can reserve for several days or more in Santiago Este. Vacation rentals offer extras such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, a vacation rental can provide a sense of privacy away from shared hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for a family trip. ### Expedia's Latest Trends Hotels - [Hotels with Free Airport Shuttle in Panama City](https://expedia.ca/Panama-City-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d2897-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels in Almirante](https://expedia.ca/Almirante-Hotels.d6245958.Travel-Guide-Hotels) - [Hotels near Banff National Park](https://expedia.ca/Banff-National-Park-Hotels.0-l602291-0.Travel-Guide-Filter-Hotels) - [Hotels in Panama City](https://expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels) - [All Inclusive Resorts and Hotels in Rio Hato](https://expedia.ca/Rio-Hato-Hotels-All-Inclusive-Hotel.0-0-d6246042-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Hotels in Bocas del Toro](https://expedia.ca/Bocas-Del-Toro-Hotels.d6023445.Travel-Guide-Hotels) Flights - [Flights to Italy](https://expedia.ca/Destinations-In-Italy.d86.Flight-Destinations) - [Flights from Kitchener (YKF) to Calgary (YYC)](https://expedia.ca/lp/flights/ykf/yyc/kitchener-to-calgary) - [Flights to Colon](https://expedia.ca/Cheap-Flights-To-Colon.d601867.Travel-Guide-Flights) - [Flights to Boca Chica](https://expedia.ca/Cheap-Flights-To-Boca-Chica.d6198033.Travel-Guide-Flights) - [Flights to Chepo](https://expedia.ca/Cheap-Flights-To-Chepo.d553248622834396118.Travel-Guide-Flights) - [Flights to Toronto](https://expedia.ca/Cheap-Flights-To-Toronto.d178314.Travel-Guide-Flights) - [Flights from Mumbai (BOM) to Toronto (YYZ)](https://expedia.ca/lp/flights/bom/yyz/mumbai-to-toronto) - [Flights to Rio Hato](https://expedia.ca/Cheap-Flights-To-Rio-Hato.d6246042.Travel-Guide-Flights) - [Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights) - [Flights to Bocas del Toro](https://expedia.ca/Cheap-Flights-To-Bocas-Del-Toro.d6023445.Travel-Guide-Flights) Cars - [Car rentals in Panama City](https://expedia.ca/Car-Rentals-In-Panama-City.d2897.Car-Rental-Guide) - [Car rentals in Rio Hato](https://expedia.ca/Car-Rentals-In-Rio-Hato.d6246042.Car-Rental-Guide) - [Car rentals in David](https://expedia.ca/Car-Rentals-In-David.d500195.Car-Rental-Guide) Activities - [Things to do in Santa Clara](https://expedia.ca/Things-To-Do-In-Santa-Clara.d553248623287315690.Travel-Guide-Activities) - [Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities) - [Things to do in Bocas del Toro](https://expedia.ca/Things-To-Do-In-Bocas-Del-Toro.d6023445.Travel-Guide-Activities) - [Things to do in Colon](https://expedia.ca/Things-To-Do-In-Colon.d601867.Travel-Guide-Activities) - [Things to do in Rio Hato](https://expedia.ca/Things-To-Do-In-Rio-Hato.d6246042.Travel-Guide-Activities) Packages - [Bocas del Toro Vacations](https://expedia.ca/Bocas-Del-Toro.d6023445.Destination-Travel-Guides) - [Rio Hato Vacations](https://expedia.ca/Rio-Hato.d6246042.Destination-Travel-Guides) - [Panama City Vacations](https://expedia.ca/Panama-City.d2897.Destination-Travel-Guides) General - [Visit Boquete](https://expedia.ca/Boquete.dx500194) - [Visit El Valle de Anton](https://expedia.ca/El-Valle-De-Anton.dx6053180) - [Visit Panama City](https://expedia.ca/Panama-City.dx2897) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)