--- title: "Book The Best Hotels in Santiago del Río for 2026 - Fully Refundable Options - Expedia" description: "Book the best hotels in Santiago del Río in 2026. Compare room rates, hotel reviews and availability. Most hotels are fully refundable." canonical: "https://www.expedia.ca/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels" language: en-CA market: CA currency: CAD prices_as_of: 2026-11-13T01:24:12Z --- Plan your trip - [Santiago del Río Travel Guide](https://www.expedia.ca/Santiago-Del-Rio.dx553248635640665145) - [Flights to Santiago del Río](https://www.expedia.ca/Cheap-Flights-To-Santiago-Del-Rio.d553248635640665145.Travel-Guide-Flights) - [Car Rentals in Santiago del Río](https://www.expedia.ca/Car-Rentals-In-Santiago-Del-Rio.d553248635640665145.Car-Rental-Guide) - [Santiago del Río Vacation Packages](https://www.expedia.ca/Santiago-Del-Rio.d553248635640665145.Destination-Travel-Guides) - [Vacation Rentals in Santiago del Río](https://www.expedia.ca/Santiago-Del-Rio-Vacation-Rentals.d553248635640665145.Travel-Guide-VacationRentals) # Find hotels in Santiago del Río ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santiago del Río [Apart­ment](https://www.expedia.ca/Hotel-Search?destination=Santiago%20del%20Río,%20Oaxaca,%20Mexico®ionId=553248635640665145&latLong=17.430839,-98.101384&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&lodging=APARTMENT) [Condo](https://www.expedia.ca/Hotel-Search?destination=Santiago%20del%20Río,%20Oaxaca,%20Mexico®ionId=553248635640665145&latLong=17.430839,-98.101384&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&lodging=CONDO) [Waterpark](https://www.expedia.ca/Hotel-Search?destination=Santiago%20del%20Río,%20Oaxaca,%20Mexico®ionId=553248635640665145&latLong=17.430839,-98.101384&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=WATER%5FPARK) ## Check prices for these dates [Check prices for these dates, December 13–14, 2026](https://www.expedia.ca/Hotel-Search?regionId=553248635640665145&startDate=2026-12-13&endDate=2026-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) [View in a map](https://www.expedia.ca/Hotel-Search?regionId=553248635640665145&stayLength=1&daysInFuture=30&pwaOverlay=map) ## Frequently Asked Questions ### What is the best area to stay in Santiago Del Río? The best area to stay in Santiago Del Río is the Historic Centre, also known as Centro, for its convenience and access to the city's main attractions. This neighbourhood is the heart of Santiago Del Río and is very walkable. It's centred around the Zócalo, the main square, which is surrounded by the Cathedral and the Government Palace. The streets branching off the Zócalo, particularly Avenida Independencia and Calle Macedonio Alcalá (a pedestrian-only street), are lined with shops, restaurants, and galleries housed in historic buildings. Couples will find the Historic Centre particularly appealing. You'll be within easy walking distance of cultural sites like the Templo de Santo Domingo de Guzmán and the Museo de las Culturas de Oaxaca. Many hotels in this area offer beautiful courtyards and rooftop terraces, superb for enjoying the city's atmosphere in the evenings. For those looking for a slightly more residential feel while still being very central, the Reforma neighbourhood is an excellent option. It's just a short taxi ride or a pleasant walk north of the Historic Centre. Reforma offers a good selection of modern hotels and a more relaxed pace, with pleasant tree-lined streets and a variety of dining options. ### When is the best time to go to Santiago Del Río? The best time to visit Santiago Del Río is during the dry season, which runs from October to May, with the peak months being November to February. During these months, you'll experience pleasant, warm days with clear skies and very little rain. The average daytime temperatures hover around 25-30°C (77-86°F), making it comfortable for exploring the outdoors and enjoying the local sights. The evenings are cooler, often dropping to around 15-20°C (59-68°F), so a light jacket or jumper is a good idea. This period is ideal for travellers who want to make the most of Santiago Del Río's natural beauty and cultural offerings without the interruption of heavy downpours. It's superb for hiking in the nearby mountains, visiting coffee plantations, or simply enjoying the town's charming streets and plazas. You'll find it easier to get around, and outdoor activities like market visits and al fresco dining are much more enjoyable. While the dry season is generally considered the best, it's also the most popular, so you might find more visitors and slightly higher prices, especially around major holidays like Christmas and Easter. ### Can I cancel my hotel reservation on Expedia? You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santiago del Río. ### How much is the nightly rate at a Santiago del Río hotel? Prices for hotels in Santiago del Río often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - [Lodging](?equalTargetTab=tab-0) - [Packages](?equalTargetTab=tab-1) - [Cars](?equalTargetTab=tab-2) - [Ixpantepec Nieves Hotels](https://www.expedia.ca/Ixpantepec-Nieves-Hotels.d553248635640640405.Travel-Guide-Hotels) - [Santiago Tamazola Hotels](https://www.expedia.ca/Santiago-Tamazola-Hotels.d553248635640637097.Travel-Guide-Hotels) - [Calihualá Hotels](https://www.expedia.ca/Calihuala-Hotels.d553248635640632815.Travel-Guide-Hotels) - [San Juan Bautista Tlachichilco Hotels](https://www.expedia.ca/San-Juan-Bautista-Tlachichilco-Hotels.d553248635640658855.Travel-Guide-Hotels) - [San Sebastián Tecomaxtlahuaca Hotels](https://www.expedia.ca/San-Sebastian-Tecomaxtlahuaca-Hotels.d553248635640660876.Travel-Guide-Hotels) - [Santiago Yucuyachi Hotels](https://www.expedia.ca/Santiago-Yucuyachi-Hotels.d553248635640633085.Travel-Guide-Hotels) - [Visit San Lorenzo Victoria](https://www.expedia.ca/San-Lorenzo-Victoria.dx553248635640642582) - [Visit Santos Reyes Tepejillo](https://www.expedia.ca/Santos-Reyes-Tepejillo.dx553248635640671563) - [Car rental Santiago Juxtlahuaca](https://www.expedia.ca/Car-Rentals-In-Santiago-Juxtlahuaca.d553248635640672179.Car-Rental-Guide) ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/ en-TW: https://www.expedia.com.tw/en/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels es-MX: https://www.expedia.mx/Santiago-Del-Rio-Hoteles.d553248635640665145.Guia-Viajes-Hoteles pt-BR: https://www.expedia.com.br/Santiago-Del-Rio-Hoteis.d553248635640665145.Guia-de-Hoteis en-GB: https://www.expedia.co.uk/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels da-DK: https://www.expedia.dk/Santiago-Del-Rio-Hoteller.d553248635640665145.Rejse-Guide-Hoteller it-IT: https://www.expedia.it/Santiago-Del-Rio-Hotel.d553248635640665145.Guida-Viaggi-Hotel en-IN: https://www.expedia.co.in/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels en-TH: https://www.expedia.co.th/en/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels zh-CN: https://www.expedia.com/cn/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels fi-FI: https://www.expedia.fi/Santiago-Del-Rio-Hotellit.d553248635640665145.Matkaoppaat-hotellit en-CA: https://www.expedia.ca/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels es-ES: https://www.expedia.es/Santiago-Del-Rio-Hoteles.d553248635640665145.Guia-Viajes-Hoteles en-ID: https://www.expedia.co.id/en/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels de-AT: https://www.expedia.at/Santiago-Del-Rio-Hotel.d553248635640665145.Reise-Angebote-Hotels fr-CA: https://www.expedia.ca/fr/Santiago-Del-Rio-Hotel.d553248635640665145.Travel-Guide-Hotels es: https://www.expedia.com/es/Santiago-Del-Rio-Hoteles.d553248635640665145.Guia-Viajes-Hoteles vi-VN: https://www.expedia.com.vn/Santiago-Del-Rio-Hotels.d553248635640665145.Huong-dan-du-lich-Khach-san en-PH: https://www.expedia.com.ph/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels nb-NO: https://www.expedia.no/Santiago-Del-Rio-Hoteller.d553248635640665145.Reise-Guide-Hoteller ja-JP: https://www.expedia.co.jp/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels ar: https://www.expedia.sa/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels th-TH: https://www.expedia.co.th/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels en-IE: https://www.expedia.ie/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels sv-SE: https://www.expedia.se/Santiago-Del-Rio-Hotell.d553248635640665145.Reseguide-Hotell en-AU: https://www.expedia.com.au/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels en-NZ: https://www.expedia.co.nz/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels nl-NL: https://www.expedia.nl/Santiago-Del-Rio-Hotels.d553248635640665145.Reisgids-Hotels en-SG: https://www.expedia.com.sg/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels ko-KR: https://www.expedia.co.kr/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels en-JP: https://www.expedia.co.jp/en/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels es-AR: https://www.expedia.com.ar/Santiago-Del-Rio-Hoteles.d553248635640665145.Guia-de-Hoteles zh-TW: https://www.expedia.com.tw/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels de-DE: https://www.expedia.de/Santiago-Del-Rio-Hotel.d553248635640665145.Reise-Angebote-Hotels en-KR: https://www.expedia.co.kr/en/Santiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels ```