Title: Santee Vacation Home Rentals from CA $184: Search Top Private Vacation Homes for Rent | Expedia.ca [Santee Travel Guide](https://expedia.ca/Santee.dx9953)[Hotels in Santee](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.ca/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.ca/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d9953.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/271db9a9db85f6f3488271b71d2f238f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Santee Vacation Rentals ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-11-07&endDate=2025-11-09&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-12-05&endDate=2025-12-07&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2026-01-02&endDate=2026-01-04&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Santee Vacation Homes ![Smart TV, offices](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/dc99579a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/431d124d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/10896652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/339c1207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! Santee 10/10 Exceptional (36) "Me and my husband had a great stay. Our 2 4 legged furry boys loved the yard so much. Would definitely stay again. " CA $141 CA $460 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109530000/109522600/109522588/4470744c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109530000/109522600/109522588/61053f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, printers](https://images.trvl-media.com/lodging/110000000/109530000/109522600/109522588/cf36fe26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, printers](https://images.trvl-media.com/lodging/110000000/109530000/109522600/109522588/0dbecbd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton Summerton CA $212 CA $446 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Summerton-Hotels-Charming-2-Bedroom-Townhome-With-AC-And-WiFi-In-Peaceful-Summerton.h109522588.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/d8b442d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1199h1600x1y0-b1f9af42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1200h1600x1y0-32d57d04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1197h1600x0y0-a4a4fa86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful brick home w/ large porch and 3 bedrooms Bowman 8.8/10 Excellent (3) "Nice and quiet property. It served us well for the weekend " CA $207 CA $391 total includes taxes & fees Oct 11 - Oct 12 [](https://www.expedia.ca/Beautiful-Brick-Home-W-Large-Porch-And-3-Bedrooms.h112528151.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/55000000/54180000/54171600/54171514/cebbaa06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/55000000/54180000/54171600/54171514/7f847335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/55000000/54180000/54171600/54171514/0ddde0a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/55000000/54180000/54171600/54171514/3ed00b84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. Eutawville 10/10 Exceptional (39) "Excellent place to stay. Nice and cozy spot. Neighbors are very nice as well. Very clean and neat place " CA $226 CA $432 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Eutawville-Hotels-Vrbo-Property.h54171514.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/df0d5860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/d3922896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/85826adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, table tennis](https://images.trvl-media.com/lodging/120000000/119470000/119463700/119463617/b1457367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Turtle Cove - Lake Living on Lake Marion Summerton CA $172 CA $592 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Summerton-Hotels-Turtle-Cove-Lake-Living-On-Lake-Marion.h119463617.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/fe01674b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, internet, bed sheets](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/fb6ca264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/dd305957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104530000/104523100/104523088/a30c8a2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sweet Marion - Dock + Boat Ramp + Hot Tub! Summerton 8.6/10 Excellent (15) "Group of us older guys went for a golf weekend at Santee. The house was great and we really enjoyed our stay." CA $173 CA $655 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Summerton-Hotels-Sweet-Marion-Dock-Boat-Ramp-Hot-Tub.h104523088.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/16d477ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/29eea974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/d113ea29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/115000000/114220000/114216100/114216027/a01795f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston Holly Hill 10/10 Exceptional (4) "Excellent stay! We will definitely be staying here again! Love this place! " CA $174 CA $224 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Holly-Hill-Hotels-Charming-2-Bedroom-Cottage-Close-To-I26-And-I95-1-Hr-From-Charleston.h114216027.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/bee5a8ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/65da7b16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/9589b5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/115000000/114290000/114282900/114282854/2f19f48d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern apartment overlooking historic downtown Elloree, SC. Elloree CA $103 CA $184 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Elloree-Hotels-Modern-Apartment-Overlooking-Historic-Downtown-Elloree.h114282854.Hotel-Information) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/119000000/118860000/118855900/118855890/ea2b2ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/119000000/118860000/118855900/118855890/53e826e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/119000000/118860000/118855900/118855890/347463eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118860000/118855900/118855890/4d90f882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4BD | 3BTH | Pool | HotTub | Games |5Miles to I-95 Elloree CA $190 CA $709 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Elloree-Hotels-4BD-3BTH-Pool-HotTub-Games-5Miles-To-I-95.h118855890.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/114000000/113030000/113026400/113026382/bd88e0b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/114000000/113030000/113026400/113026382/fab3138f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113030000/113026400/113026382/09c89483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113030000/113026400/113026382/c4f59ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reel Haven on the Water: Modern + Comfy Home! Eutawville 6.0/10 (4) "Perfect place for a weekend fishing trip. Owner was responsive. Slept 6 easily. Only stayed one night but was a perfect fit" CA $124 CA $525 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Eutawville-Hotels-Reel-Haven-On-The-Water-Modern-Comfy-Home.h113026382.Hotel-Information) ![1 bedroom, in-room safe, WiFi, bed sheets](https://images.trvl-media.com/lodging/88000000/87980000/87972600/87972565/fb69157a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, bathrobes, towels](https://images.trvl-media.com/lodging/88000000/87980000/87972600/87972565/w449h683x288y0-8fb90fc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, bathrobes, towels](https://images.trvl-media.com/lodging/88000000/87980000/87972600/87972565/fe737fd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87980000/87972600/87972565/w449h683x287y0-8c43cd49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private entrance charming room with clawfoot tub. Elloree 4.0/10 (1) "This pains me to write because this could’ve been a great little stopping point, however the bathtub was actually filthy. It smelled like urine and there is a dark grey film that needs to be scrubbed off. I get that old tubs can have stains but these are not stains and could’ve been removed with cleaner and elbow grease. I had camped for a week and just wanted to take a nice hot bath; I did not get to take one. Also I would add a sign for the cottage because it was confusing as to which door it... CA $209 CA $300 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Elloree-Hotels-Private-Entrance-Charming-Room-With-Clawfoot-Tub.h87972565.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-21&endDate=2025-10-22®ionId=9953&adults=2&lodging=VACATION_HOME&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Private-Vacation-Homes.d9953-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Private-Vacation-Homes.d9953-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Santee Hotel Reviews ![Fairfield Inn & Suites by Marriott Santee](//images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 10/10 Excellent "Clean room. Great Staff " [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Tru By Hilton Santee](//images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "Everything was great! Room 319 AC was a little nosy but we really enjoyed our overnight stay. Staff are super friendly and very helpful!" [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!](//images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/dc99579a_y.jpg) ### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! 10/10 Excellent "Great house, very modern interior. Very clean. Close to town. We’ll definitely book the house on our fishing trip. " [](https://expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) ![Hampton Inn Santee-I-95](//images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "We had a nice and courteous and friendly. Bed was comfortable " [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Baymont by Wyndham Santee](//images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 10/10 Excellent "Quiet " [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Travelodge by Wyndham Santee](//images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg) ### Travelodge by Wyndham Santee 10/10 Excellent "The property is old. The room was clean but dated. Plumbing fixtures all need to replaced. Great for an overnight stay and the value, however, I would not bring my wife there." [](https://expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Holiday Inn Santee by IHG](//images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg) ### Holiday Inn Santee by IHG 10/10 Excellent "Easy, convenient, clesn" [](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Quality Inn & Suites](//images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053_y.jpg) ### Quality Inn & Suites 10/10 Excellent "Great place. Excellent people. Great service" [](https://expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Ramada by Wyndham Santee I-95](//images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6_y.jpg) ### Ramada by Wyndham Santee I-95 10/10 Excellent "The grounds and property were clean and you could tell they take pride in what they're offering." [](https://expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ## Find out more about Santee ## Santee Vacation Homes information | Number of reviews | 96 | | --- | --- | | Accommodation | 68 Vacation Homes | | Lowest Price | CA $184 | | Highest Price | CA $655 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Manning](https://www.expedia.ca/5Star-Manning-Hotels.s50-0-d8454.Travel-Guide-Filter-Hotels) - [B&B in Bowman](https://www.expedia.ca/Bowman-Bed-And-Breakfast.d553248634998681915-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Red Roof Inn Hotels in Bowman](https://www.expedia.ca/Bowman-Hotels-Red-Roof-Inn.0-0-d553248634998681915--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Bowman Hotels](https://www.expedia.ca/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Apartments in Brookdale](https://www.expedia.ca/Brookdale-Apartments.d553248634999003908-aaApartments.Travel-Guide-Accommodation) - 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