Title: Hotels by Ayres Collection in Santee | Expedia.ca [Santee Travel Guide](https://expedia.ca/Santee.dx6678)[Hotels in Santee](https://expedia.ca/Santee-Hotels.d6678.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.ca/Santee-Vacation-Rentals.d6678.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.ca/Cheap-Flights-To-Santee.d6678.Travel-Guide-Flights)[Things to do in Santee](https://expedia.ca/Things-To-Do-In-Santee.d6678.Travel-Guide-Activities)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d6678.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d6678.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/3073/47ddac67-5969-41c0-8843-96304c5986bd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Ayres Collection in Santee - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 9 - Jan 10](https://www.expedia.ca/Hotel-Search?regionId=6678&startDate=2026-01-09&endDate=2026-01-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 10 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6678&startDate=2026-01-10&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6678&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6678&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels-Ayres-Collection.0-0-d6678--bAyresCollection.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels-Ayres-Collection.0-0-d6678--bAyresCollection.Travel-Guide-Filter-Hotels) ## Top Santee Hotel Reviews ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Can room" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "都很好" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Loved the location and so nice!" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "the staff is great! their service is amazing!" [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](https://images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "We had a great stay. The room was clean, the staff friendly and helpful, and the breakfast was excellent." [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent " Overall great hotel. All staff were very friendly and the Christmas decorations were beautiful. Had a great experience. Would love to come back in the future!!" [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "From the moment we check in the staff was always courteous and attentive to all of our needs. We were even given a wonderful surprise from the Hotel delivered to our suite, a bottle of champagne and desert." [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "great" [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Beautiful views from room 248! Great service throughout our stay from all the departments! Quiet, serenely quiet which we really enjoyed. Everything was clean, spacious, kept up and easy to navigate." 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