Title: Book the Best BUSINESS Hotels in Santa Susana in 2025 | Expedia.ca [Vacation Rentals in Simi Valley](https://expedia.ca/Simi-Valley-Vacation-Rentals.d6894.Travel-Guide-VacationRentals)[Flights to Simi Valley](https://expedia.ca/Cheap-Flights-To-Simi-Valley.d6894.Travel-Guide-Flights)[Things to do in Simi Valley](https://expedia.ca/Things-To-Do-In-Simi-Valley.d6894.Travel-Guide-Activities)[Santa Susana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Susana.d6340842.Car-Rental-Guide)[Santa Susana Vacations](https://expedia.ca/Santa-Susana.d6340842.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/b896caa52309cedbebd5afbd9a25ceff.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Santa Susana, CA from CA $121 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Susana Business Hotels Tonight [Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6340842&startDate=2025-10-11&endDate=2025-10-12&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=6340842&startDate=2025-10-12&endDate=2025-10-13&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6340842&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6340842&startDate=2025-10-24&endDate=2025-10-26&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Susana Business Hotels ![Exterior](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144930/3f960f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144930/3b3dded0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144930/e2a6e935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144930/6d270227.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Suites Los Angeles Simi Valley Santa Susana 7.2/10 Good (1006) "We stayed there for two nights and the place was quiet, clean and the breakfast was good." CA $145 CA $163 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Simi-Valley-Hotels-Extended-Stay-America-Suites-Los-Angeles-Simi-Valley.h1144930.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/80cbfa59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/1bab978a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/f95d530d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/140c9052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Anza - A Calabasas Hotel Calabasas 8.6/10 Excellent (258) "We have booked here many many times and enjoy each time love the surrounding town everything walkable if you want to or drivable if you feel up to it" CA $156 CA $176 total includes taxes & fees Nov 8 - Nov 9 [](https://www.expedia.ca/Los-Angeles-Hotels-The-Anza-A-Calabasas-Hotel.h3917.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/9847c5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/c97d28a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/a75616a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/637112b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Santa Clarita - Valencia Stevenson Ranch 9.2/10 Wonderful (1861) "Good location and great front desk staff" CA $175 CA $197 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Los-Angeles-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Clarita-Valencia.h1550158.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/70000000/69320000/69317300/69317258/d30765bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/70000000/69320000/69317300/69317258/d8da694c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/70000000/69320000/69317300/69317258/5475202b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/70000000/69320000/69317300/69317258/160ef368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Calabasas - Malibu Calabasas 9.4/10 Exceptional (1225) "This hotel is wonderful...very friendly staff from check in to restaurant staff.. Beautiful hotel and kind staff... " CA $189 CA $212 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Los-Angeles-Hotels-Cambria-Hotel-Calabasas-Malibu.h69317258.Hotel-Information) ![Family House, Garden View](https://images.trvl-media.com/lodging/122000000/121400000/121397600/121397563/296da465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Garden View](https://images.trvl-media.com/lodging/122000000/121400000/121397600/121397563/b28def7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Parking](https://images.trvl-media.com/lodging/122000000/121400000/121397600/121397563/eb014148.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/122000000/121400000/121397600/121397563/a6e81de2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Zuma by Oraklus Western Malibu CA $1,751 CA $2,644 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Los-Angeles-Hotels-Casa-Zuma-By-Oraklus.h121397563.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/ada3792d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/6108abdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/97aadd13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/9068376b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Valencia - Santa Clarita by IHG Valencia 9.4/10 Exceptional (1013) "Great stay " CA $156 CA $175 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Los-Angeles-Hotels-Holiday-Inn-Express-Suites-Valencia-Santa-Clarita.h54081573.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/12900/12864/b049f617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/12900/12864/d2490f99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12864/10234be3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 11:00 AM to 7:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/12900/12864/47bb56b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Los Angeles/Santa Clarita Stevenson Ranch 8.8/10 Excellent (1673) "GREAT HOTEL, GREAT LOCATION!!!" CA $150 CA $168 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Los-Angeles-Hotels-Hampton-Inn-Los-Angeles-Santa-Clarita.h12864.Hotel-Information) ![Room, 2 Queen Beds, Balcony, Pool View | View from room](https://images.trvl-media.com/lodging/2000000/1640000/1632200/1632124/f3e32b0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1632200/1632124/62498977.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1632200/1632124/f4ab9667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1640000/1632200/1632124/6395c27f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Santa Clarita Valencia Valencia 9.2/10 Wonderful (1016) "Great staff, nice accommodations, convenient location and facilities " CA $165 CA $186 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Los-Angeles-Hotels-Courtyard-By-Marriott-Santa-Clarita-Valencia.h1632124.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/110000/103200/103128/cc4b3f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; alfresco dining](https://images.trvl-media.com/lodging/1000000/110000/103200/103128/7ecace4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/110000/103200/103128/0008261d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden view](https://images.trvl-media.com/lodging/1000000/110000/103200/103128/ae5ac418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Valencia Valencia 9.0/10 Wonderful (1166) "Great relaxing hotel. Food and breakfast was perfect" CA $202 CA $226 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Los-Angeles-Hotels-Hyatt-Regency-Valencia.h103128.Hotel-Information) ![Queen Room](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/8aac443d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Room](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/w1995h1333x0y0-5ffd0ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/dc40480e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/6d78483d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santa Clarita Motel Newhall 8.8/10 Excellent (1012) "Great stay over for our trip to Arizona " CA $108 CA $121 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Los-Angeles-Hotels-Santa-Clarita-Motel.h84912.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6340842&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Susana Hotel Reviews ![Hampton Inn Los Angeles/Santa Clarita](//images.trvl-media.com/lodging/1000000/20000/12900/12864/b049f617_y.jpg) ### Hampton Inn Los Angeles/Santa Clarita 10/10 Excellent "Very clean rooms, quiet, the staff was very friendly and accommodating. We will be making several more trips to this area due to my sister's health and her specialists in this area. So, we have found a place to stay during her surgery and treatments." [](https://expedia.ca/Los-Angeles-Hotels-Hampton-Inn-Los-Angeles-Santa-Clarita.h12864.Hotel-Information) ![Comfort Inn & Suites Near Universal - N. Hollywood - Burbank](//images.trvl-media.com/lodging/2000000/1590000/1588400/1588303/0ccb0c97_y.jpg) ### Comfort Inn & Suites Near Universal - N. Hollywood - Burbank 10/10 Excellent "Nice service " [](https://expedia.ca/Los-Angeles-Hotels-Comfort-Inn-Suites-Near-Universal-N-Hollywood-Burbank.h1588303.Hotel-Information) ![Luskin Hotel](//images.trvl-media.com/lodging/18000000/17840000/17837200/17837136/6458aca2_y.jpg) ### Luskin Hotel 10/10 Excellent "Great " [](https://expedia.ca/Los-Angeles-Hotels-Luskin-Hotel.h17837136.Hotel-Information) ![Holiday Inn Express Van Nuys by IHG](//images.trvl-media.com/lodging/1000000/30000/21600/21558/4a5612d3_y.jpg) ### Holiday Inn Express Van Nuys by IHG 10/10 Excellent "Everything was clean and staff was very polite and helpful and breakfast was great. We are differently staying here again and telling all our friends and family to do so." [](https://expedia.ca/Los-Angeles-Hotels-Holiday-Inn-Express-Van-Nuys.h21558.Hotel-Information) ![Valley Inn](//images.trvl-media.com/lodging/1000000/30000/25500/25485/9ac61f46_y.jpg) ### Valley Inn 10/10 Excellent "It was just right good service " [](https://expedia.ca/Los-Angeles-Hotels-Valley-Inn.h25485.Hotel-Information) ![Studio City Court Yard Hotel](//images.trvl-media.com/lodging/1000000/50000/42500/42444/2e6e17fa_y.jpg) ### Studio City Court Yard Hotel 10/10 Excellent "Clean room nice staff" [](https://expedia.ca/Los-Angeles-Hotels-Studio-City-Court-Yard-Hotel.h42444.Hotel-Information) ![Hotel Angeleno](//images.trvl-media.com/lodging/1000000/30000/21900/21848/c152e381_y.jpg) ### Hotel Angeleno 10/10 Excellent "Good experience, near ucla ,busy breakfast with wait" [](https://expedia.ca/Los-Angeles-Hotels-Hotel-Angeleno.h21848.Hotel-Information) ![Hilton Garden Inn Calabasas](//images.trvl-media.com/lodging/1000000/890000/889300/889222/6b3ea089_y.jpg) ### Hilton Garden Inn Calabasas 10/10 Excellent "The front desk staff super helpful and friendly " [](https://expedia.ca/Los-Angeles-Hotels-Hilton-Garden-Inn-Calabasas.h889222.Hotel-Information) ![Hilton Woodland Hills / Los Angeles](//images.trvl-media.com/lodging/1000000/10000/7400/7317/5c77813d_y.jpg) ### Hilton Woodland Hills / Los Angeles 10/10 Excellent "Very clean. Large room. Very comfortable bed. Great staff! " [](https://expedia.ca/Los-Angeles-Hotels-Hilton-Woodland-Hills-Los-Angeles.h7317.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Santa Susana with Expedia? > Expedia is here to help you find a great business-friendly hotel when you need to travel for work. From conference spaces and meeting rooms to on-site cafés and restaurants, our properties have the things you'll need to settle that big contract. ### How can I find cheap business-friendly hotels in Santa Susana? > When work takes you on the road in Santa Susana, our "business friendly" filter will help you find the perfect hotel. From WiFi to computer stations and concierge services, they come with the amenities you need for a comfortable and productive stay. 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