Title: Book the Best BUSINESS Hotels in Santa Susana in 2025 | Expedia.ca [Vacation Rentals in Simi Valley](https://expedia.ca/Simi-Valley-Vacation-Rentals.d6894.Travel-Guide-VacationRentals)[Flights to Simi Valley](https://expedia.ca/Cheap-Flights-To-Simi-Valley.d6894.Travel-Guide-Flights)[Things to do in Simi Valley](https://expedia.ca/Things-To-Do-In-Simi-Valley.d6894.Travel-Guide-Activities)[Santa Susana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Susana.d6340842.Car-Rental-Guide)[Santa Susana Vacations](https://expedia.ca/Santa-Susana.d6340842.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/b896caa52309cedbebd5afbd9a25ceff.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Santa Susana, CA from CA $121 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Susana Business Hotels Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6340842&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6340842&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6340842&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6340842&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Santa Susana Business Hotels ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144930/468ddd7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144930/415b2a11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144930/3ada8d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/2000000/1150000/1145000/1144930/e2a6e935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Suites Los Angeles Simi Valley Santa Susana 7.4/10 Good (1000) "We stayed there for two nights and the place was quiet, clean and the breakfast was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ignacio CA $132 CA $148 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Simi-Valley-Hotels-Extended-Stay-America-Suites-Los-Angeles-Simi-Valley.h1144930.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/80cbfa59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/1bab978a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/140c9052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/e3e4b41f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Anza - A Calabasas Hotel Calabasas 8.6/10 Excellent (310) "Good sized room, quiet, comfortable bed and good sized bathroom. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) steven CA $171 CA $191 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Los-Angeles-Hotels-The-Anza-A-Calabasas-Hotel.h3917.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/70000000/69320000/69317300/69317258/d30765bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/70000000/69320000/69317300/69317258/160ef368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, desk, laptop workspace](https://images.trvl-media.com/lodging/70000000/69320000/69317300/69317258/b3d1ec78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/70000000/69320000/69317300/69317258/5475202b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Calabasas - Malibu Calabasas 9.4/10 Exceptional (1240) "It was a very peaceful stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Taylor CA $188 CA $211 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Los-Angeles-Hotels-Cambria-Hotel-Calabasas-Malibu.h69317258.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/9847c5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/c97d28a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/29937a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/a75616a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Santa Clarita - Valencia Stevenson Ranch 9.2/10 Wonderful (1864) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $174 CA $196 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Los-Angeles-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Clarita-Valencia.h1550158.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/ada3792d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/97aadd13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/6108abdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/e1f92b50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Valencia - Santa Clarita by IHG Valencia 9.4/10 Exceptional (1033) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $159 CA $178 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Los-Angeles-Hotels-Holiday-Inn-Express-Suites-Valencia-Santa-Clarita.h54081573.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/12900/12864/b049f617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12864/10234be3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12864/1bb2f524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/12900/12864/d2490f99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Los Angeles/Santa Clarita Stevenson Ranch 8.8/10 Excellent (1702) "Good breakfast and helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander CA $144 CA $161 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Los-Angeles-Hotels-Hampton-Inn-Los-Angeles-Santa-Clarita.h12864.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/110000/103200/103128/cc4b3f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/110000/103200/103128/0008261d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden view](https://images.trvl-media.com/lodging/1000000/110000/103200/103128/ae5ac418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/110000/103200/103128/f84aa418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Valencia Valencia 9.0/10 Wonderful (1178) "Excellent property good staff and great restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $201 CA $225 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Los-Angeles-Hotels-Hyatt-Regency-Valencia.h103128.Hotel-Information) ![Queen Room](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/8aac443d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/dc40480e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Room](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/w1995h1333x0y0-5ffd0ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Room | Bathroom](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/699d89eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santa Clarita Motel Newhall 8.8/10 Excellent (1027) "Clean and good place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yasir CA $107 CA $121 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Los-Angeles-Hotels-Santa-Clarita-Motel.h84912.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1750000/1747300/1747235/79768f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1747300/1747235/f3c4d394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1750000/1747300/1747235/176180a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1750000/1747300/1747235/e979c547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton Valencia Valencia 9.0/10 Wonderful (1001) "Very good breakfast and customer service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorena CA $171 CA $191 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Los-Angeles-Hotels-Embassy-Suites-By-Hilton-Valencia.h1747235.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/1000000/30000/23000/22953/5e8d767f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/1000000/30000/23000/22953/4af35b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23000/22953/be1cd483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/23000/22953/04928d4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Vista Hotel Simi Valley 8.2/10 Very good (1440) "there was some nice restaurants around the property within a mile" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $128 CA $144 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Simi-Valley-Hotels-Grand-Vista-Hotel.h22953.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=6340842&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Susana Hotel Reviews ![Hotel Angeleno](//images.trvl-media.com/lodging/1000000/30000/21900/21848/7bddbf3f_y.jpg) ### Hotel Angeleno 10/10 Excellent "Thanks for all free uber service for sightseeing!" [](https://expedia.ca/Los-Angeles-Hotels-Hotel-Angeleno.h21848.Hotel-Information) ![Palm Garden Hotel](//images.trvl-media.com/lodging/1000000/20000/10300/10241/54ccf1fa_y.jpg) ### Palm Garden Hotel 10/10 Excellent "Amazing " [](https://expedia.ca/Los-Angeles-Hotels-Palm-Garden-Hotel.h10241.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Santa Clarita - Valencia](//images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/9847c5b2_y.jpg) ### La Quinta Inn & Suites by Wyndham Santa Clarita - Valencia 10/10 Excellent "I would like to give a shout out to Mary who worked her magic to get us into a room quickly as we were short on time for a wedding. She met all of our expectations and honored everything we requested (early check-in, 3rd floor) and did so quickly, efficiently, and cheerfully!" [](https://expedia.ca/Los-Angeles-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Clarita-Valencia.h1550158.Hotel-Information) ![Motel 6 Thousand Oaks, CA](//images.trvl-media.com/lodging/1000000/990000/983700/983645/feff5327_y.jpg) ### Motel 6 Thousand Oaks, CA 10/10 Excellent "Motel 6 always been a hit or a miss. This Thousands Oaks motel 6 is one of the best. " [](https://expedia.ca/Los-Angeles-Hotels-Motel-6-Thousand-Oaks.h983645.Hotel-Information) ![Holiday Inn Express Van Nuys by IHG](//images.trvl-media.com/lodging/1000000/30000/21600/21558/4a5612d3_y.jpg) ### Holiday Inn Express Van Nuys by IHG 10/10 Excellent "Clean room,however shower wasnt the cleanest. 5 stars will be returning " [](https://expedia.ca/Los-Angeles-Hotels-Holiday-Inn-Express-Van-Nuys.h21558.Hotel-Information) ![Best Western Valencia/Six Flags Inn & Suites](//images.trvl-media.com/lodging/1000000/910000/908700/908621/99775826_y.jpg) ### Best Western Valencia/Six Flags Inn & Suites 10/10 Excellent "Breakfast was great!" [](https://expedia.ca/Los-Angeles-Hotels-Best-Western-ValenciaSix-Flags-Inn-Suites.h908621.Hotel-Information) ![Hilton Garden Inn Calabasas](//images.trvl-media.com/lodging/1000000/890000/889300/889222/6b3ea089_y.jpg) ### Hilton Garden Inn Calabasas 10/10 Excellent "Great customer service and clean rooms " [](https://expedia.ca/Los-Angeles-Hotels-Hilton-Garden-Inn-Calabasas.h889222.Hotel-Information) ![Best Western Plus Carriage Inn](//images.trvl-media.com/lodging/1000000/10000/4800/4753/dafb2af3_y.jpg) ### Best Western Plus Carriage Inn 10/10 Excellent "I stay here once a month when I come in for a business meeting. It is the best around for the location and service." [](https://expedia.ca/Los-Angeles-Hotels-Best-Western-Plus-Carriage-Inn.h4753.Hotel-Information) ![Valley Inn](//images.trvl-media.com/lodging/1000000/30000/25500/25485/9ac61f46_y.jpg) ### Valley Inn 10/10 Excellent "Area was convenient, close to everything. Walls in the restroom/door could have been wiped down. Shower and room clean. It was a truck stop place but would stay again. " [](https://expedia.ca/Los-Angeles-Hotels-Valley-Inn.h25485.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Santa Susana with Expedia? > Expedia is here to help you find a great business-friendly hotel when you need to travel for work. From conference spaces and meeting rooms to on-site cafés and restaurants, our properties have the things you'll need to settle that big contract. ### How can I find cheap business-friendly hotels in Santa Susana? > When work takes you on the road in Santa Susana, our "business friendly" filter will help you find the perfect hotel. From WiFi to computer stations and concierge services, they come with the amenities you need for a comfortable and productive stay. 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