Title: Book The Best Hotels in Santa María Centro for 2026 from CA $138 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Santa María Centro](https://expedia.ca/Santa-Maria-Centro-Vacation-Rentals.d553248635923647958.Travel-Guide-VacationRentals)[Santa María Centro Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Maria-Centro.d553248635923647958.Car-Rental-Guide)[Santa María Centro Vacation Packages](https://expedia.ca/Santa-Maria-Centro.d553248635923647958.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Apr 5 - Apr 6](https://www.expedia.ca/Hotel-Search?regionId=553248635923647958&startDate=2026-04-05&endDate=2026-04-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 6 - Apr 7](https://www.expedia.ca/Hotel-Search?regionId=553248635923647958&startDate=2026-04-06&endDate=2026-04-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=553248635923647958&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=553248635923647958&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa María Centro hotels ![Outdoor spa tub](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/eae29abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/7c52245d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/w3248h3120x0y0-30cfe3d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/fe30d3b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amerian Rafaela Hotel [](https://www.expedia.ca/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) Rafaela 9.0/10 Wonderful (47 reviews) "Nice hotel and staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix CA $138 CA $138 total Apr 27 - Apr 28 [](https://www.expedia.ca/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-19&endDate=2026-04-20®ionId=553248635923647958&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Centro-Hotels.d553248635923647958.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Centro-Hotels.d553248635923647958.Travel-Guide-Hotels) ## Top Santa María Centro Hotel Reviews ## More cheap stays in Santa María Centro ![Parra Hotel& Suites](https://images.trvl-media.com/lodging/16000000/15470000/15462700/15462633/02bbafda_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Parra Hotel& Suites BV. SANTA FE 554,Rafaela, Santa Fe, Argentina Rafaela Santa Fe Province [Get rates](https://expedia.ca/Hotel-Search?startDate=19%2F04%2F2026&endDate=20%2F04%2F2026&selected=15462633&PinnedHotelID=15462633&HadPinnedHotel=true®ionId=553248635923647958) [](https://expedia.ca/Rafaela-Hotels-Parra-Hotel-Suites.h15462633.Hotel-Information) ![PARRA HOTEL AND SUITES](https://images.trvl-media.com/lodging/127000000/126530000/126529800/126529772/813bf13a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### PARRA HOTEL AND SUITES 554 Bv. Sta. Fe Rafaela Santa Fe [Get rates](https://expedia.ca/Hotel-Search?startDate=19%2F04%2F2026&endDate=20%2F04%2F2026&selected=126529772&PinnedHotelID=126529772&HadPinnedHotel=true®ionId=553248635923647958) [](https://expedia.ca/Rafaela-Hotels-PARRA-HOTEL-AND-SUITES.h126529772.Hotel-Information) ![Hotel Campo Alegre](https://images.trvl-media.com/lodging/119000000/118160000/118152900/118152802/2dc6794e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Campo Alegre Ruta 34 km 224 Rafaela Santa Fe Province [Get rates](https://expedia.ca/Hotel-Search?startDate=19%2F04%2F2026&endDate=20%2F04%2F2026&selected=118152802&PinnedHotelID=118152802&HadPinnedHotel=true®ionId=553248635923647958) [](https://expedia.ca/Rafaela-Hotels-Hotel-Campo-Alegre.h118152802.Hotel-Information) ![Hotel Toscano](https://images.trvl-media.com/lodging/119000000/118010000/118000100/118000033/542b749e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Toscano Av Santa Fe 442 Rafaela Santa Fe Province [Get rates](https://expedia.ca/Hotel-Search?startDate=19%2F04%2F2026&endDate=20%2F04%2F2026&selected=118000033&PinnedHotelID=118000033&HadPinnedHotel=true®ionId=553248635923647958) [](https://expedia.ca/Rafaela-Hotels-Hotel-Toscano.h118000033.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santa María Centro? > This central area is the heart of Santa María Centro and is very convenient for visitors. It's characterised by its tree-lined streets, historic buildings, and a good selection of shops, eateries, and services. Plaza San Martín is a key landmark, a large, well-maintained park that often hosts local events and provides a pleasant green space in the city centre. Avenida General San Martín, a main thoroughfare, runs through this district and is where you'll find many of the city's businesses and hotels. > > > Couples will find this central location ideal for a relaxing and enjoyable stay. You'll be within easy walking distance of quality restaurants, local cafes, and boutique shops, superb for an evening stroll. The proximity to Plaza San Martín also offers a pleasant spot for a quiet afternoon. > > > For solo travellers, staying in the centre offers convenience and ease of access to the city's amenities. You can easily navigate on foot to explore local attractions, and there are public transport options available if you wish to venture further afield. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa María Centro hotel booking with Expedia? ### How much is the nightly rate at a Santa María Centro hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Angélica Hotels ](https://www.expedia.ca/Angelica-Hotels.d553248635924012085.Travel-Guide-Hotels) - [Ataliva Hotels ](https://www.expedia.ca/Ataliva-Hotels.d553248635924012203.Travel-Guide-Hotels) - [Bauer y Sigel Hotels ](https://www.expedia.ca/Bauer-Y-Sigel-Hotels.d553248635924011523.Travel-Guide-Hotels) - [Bigand Hotels ](https://www.expedia.ca/Bigand-Hotels.d553248635924011810.Travel-Guide-Hotels) - [Campo Piaggio Hotels ](https://www.expedia.ca/Campo-Piaggio-Hotels.d553248635923281277.Travel-Guide-Hotels) - [Colonia Belgrano Hotels ](https://www.expedia.ca/Colonia-Belgrano-Hotels.d553248635924012267.Travel-Guide-Hotels) - 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