Title: Book the Best Santa Margarita SPA Resorts from CA $222 - Spa Hotels in Santa Margarita, CA | Expedia.ca [Santa Margarita Travel Guide](https://expedia.ca/Santa-Margarita.dx6150927)[Hotels in Santa Margarita](https://expedia.ca/Santa-Margarita-Hotels.d6150927.Travel-Guide-Hotels)[Vacation Rentals in Santa Margarita](https://expedia.ca/Santa-Margarita-Vacation-Rentals.d6150927.Travel-Guide-VacationRentals)[Santa Margarita Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Margarita.d6150927.Car-Rental-Guide)[Santa Margarita Vacation Packages](https://expedia.ca/Santa-Margarita.d6150927.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/9f107200a31c7a25dda8ed3127198c44.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Mariam Qozi # Find Spa Hotels in Santa Margarita, CA from CA $222 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Margarita Spa Hotels Tonight [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=6150927&startDate=2025-11-03&endDate=2025-11-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6150927&startDate=2025-11-04&endDate=2025-11-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6150927&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6150927&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Margarita Spa Hotels ![Lobby](https://images.trvl-media.com/lodging/31000000/30440000/30434900/30434871/5a66e4d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/31000000/30440000/30434900/30434871/fcbcdcca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/31000000/30440000/30434900/30434871/e828a7b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/31000000/30440000/30434900/30434871/2d4eae32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oxford Suites Paso Robles Paso Robles 9.6/10 Exceptional (1608) "Our stay at the Oxford Suites was great. Clean rooms, comfortable beds and great breakfast selections. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $251 CA $304 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Paso-Robles.h30434871.Hotel-Information) ![Caveman | Bathroom](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/29ce234c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Highway Suite](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/59b09fa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/01a54722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/5a091377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madonna Inn San Luis Obispo 9.2/10 Wonderful (1291) "Absolutely amazing stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zachary A CA $188 CA $262 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/9e66f2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/323aabf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/1d10b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/37000000/36120000/36117600/36117545/4e72b30d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Agrarian Hotel, BW Signature Collection Arroyo Grande 9.6/10 Exceptional (1010) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathy CA $195 CA $222 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-The-Agrarian-Hotel.h36117545.Hotel-Information) ![Yoga](https://images.trvl-media.com/lodging/8000000/7720000/7714700/7714654/9a646e8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Massages](https://images.trvl-media.com/lodging/8000000/7720000/7714700/7714654/ff1e8d96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/8000000/7720000/7714700/7714654/24d78d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/8000000/7720000/7714700/7714654/28305f83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Allegretto Vineyard Resort Paso Robles River Oaks 9.6/10 Exceptional (1443) "Beautiful property wonderful staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerry CA $314 CA $360 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Allegretto-Vineyard-Resort-Paso-Robles.h7714654.Hotel-Information) ![At Last ADA Compliant](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/869d446f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/4a105f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Country Roads](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/12da2465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![At Last ADA Compliant | Terrace/patio](https://images.trvl-media.com/lodging/54000000/53980000/53975600/53975592/3062deb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Geneseo Inn Paso Robles 10/10 Exceptional (68) "This place was amazing! The rooms are beautiful and the complimentary breakfast they offer is very tasty and filling. The property has many amenities. The cafe offers many delectable foods and the wine tasting is amazing." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorena CA $400 CA $494 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-GENESEO-INN.h53975592.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/09f8fafa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/af3dfd64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/4adefcff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room, 2 Queen Beds | Exterior](https://images.trvl-media.com/lodging/2000000/1840000/1839900/1839838/6a62dfc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Pines Resort Los Osos 8.2/10 Very good (406) "wonderful peaceful getaway in beautiful Los Osos, CA" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia CA $223 CA $282 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Sea-Pines-Resort.h1839838.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/46c8343c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/10b1b07e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/d2bd3038.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite, 1 King Bed, Non Smoking, Ocean View](https://images.trvl-media.com/lodging/36000000/35830000/35826200/35826166/8e1a2a5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cayucos Sunset Inn B&B Cayucos 9.8/10 Exceptional (192) "Fantastic location, beautiful rooms, absolutely incredible breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dianne CA $243 CA $274 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Cayucos-Sunset-Inn-Bed-And-Breakfast.h35826166.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/42ac20df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/18ffa136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/41f2d375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48257700/48257614/dd32277b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CERRO, Autograph Collection Downtown San Luis Obispo 9.2/10 Wonderful (461) "Best hotel in SLO. Great location to walk to anywhere downtown. Beautiful rooms. Bathroom could have used a second sink, but overall top notch. Loved the rooftop pool with bar. Very friendly staff. Will be back. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Helmut CA $283 CA $370 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-Cerro.h48257614.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/c2c4905d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Room, 1 King Bed (Spa Room) | Library](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/2d3891c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/cd3bd54d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Double Room (Great Room) | Room amenity](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/5728603e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila La Fonda Hotel Avila Beach 9.6/10 Exceptional (1002) "Our Stay at the hotel was 10/10 Thank you for making us feel welcome and spoiled! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Manuel CA $254 CA $286 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) ![Morro Suite | Living area](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Tolosa Terrace King](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/cdd4facb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Paseo King Room](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/0c2ec67b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/b4e2ccc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Luis Obispo Downtown San Luis Obispo 9.4/10 Exceptional (539) "Beautiful design, so lovely. Ended up staying on property. Great staff:)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kelly CA $415 CA $471 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18®ionId=6150927&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Margarita Hotel Reviews ![Madonna Inn](//images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "Great room - Merry. 20 foot ceiling with pink glittery wall paper and a large gold and crystal light fixtures and giant chandelier. Quirky hotel (as expected) but well maintained. Nice pool area. Signature pink cloud cocktail was very . . . pink (and tasted fine)! Wonderful meal at the steak house. Pink champagne cake was pretty amazing and lived up to the hype. Waterfall urinal in men's room near the restaurant was over the top! Would stay here again. Should have broken up the long drive from LA to the Bay Area with a stay here long ago. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Historic Santa Maria Inn](//images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c_y.jpg) ### Historic Santa Maria Inn 10/10 Excellent "The staff was AMAZING! Everyone was soo nice. We stayed in the original wing of the hotel and our room was decent. We had breakfast at their restaurant down stairs and it was delicious." [](https://expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Allegretto Vineyard Resort Paso Robles](//images.trvl-media.com/lodging/8000000/7720000/7714700/7714654/28305f83_y.jpg) ### Allegretto Vineyard Resort Paso Robles 10/10 Excellent "We had a very nice suite on the backside overlooking the hill and vineyard. Very quiet. Two parts to the suite, where the separate part was the lounge area. Grounds are wonderful with many art objects. Breakfast is very good with a nice selection. Will definitely be back again. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Allegretto-Vineyard-Resort-Paso-Robles.h7714654.Hotel-Information) ![Oxford Suites Pismo Beach](//images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "Great breakfast!" [](https://expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Paso Robles](//images.trvl-media.com/lodging/2000000/1580000/1572400/1572314/7df8871e_y.jpg) ### La Quinta Inn & Suites by Wyndham Paso Robles 10/10 Excellent "The hotel was clean and updated. We stayed to attend a wedding nearby, and it was perfect. They were even able to accommodate our early check-in request." [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Paso-Robles.h1572314.Hotel-Information) ![Embassy Suites by Hilton San Luis Obispo](//images.trvl-media.com/lodging/1000000/20000/15500/15406/48c2929b_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 10/10 Excellent "Nice breakfast clean room very helpful staff" [](https://expedia.ca/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Shore Cliff Hotel](//images.trvl-media.com/lodging/1000000/10000/9800/9742/ff9d613b_y.jpg) ### Shore Cliff Hotel 10/10 Excellent "Staff, view, amenities." [](https://expedia.ca/San-Luis-Obispo-Hotels-Shore-Cliff-Hotel.h9742.Hotel-Information) ![Edgewater Inn And Suites](//images.trvl-media.com/lodging/1000000/900000/894000/893902/3d1c5694_y.jpg) ### Edgewater Inn And Suites 10/10 Excellent "Room was very clean, staff friendly, extras like snacks and grab and go breakfast. Will stay here again." [](https://expedia.ca/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![Cottage Inn By The Sea](//images.trvl-media.com/lodging/1000000/160000/151000/150921/c54d7346_y.jpg) ### Cottage Inn By The Sea 10/10 Excellent "Beautiful views and it is a very clean hotel" [](https://expedia.ca/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) ## Frequently asked questions ### How much does a spa hotel in Santa Margarita cost? > Enjoy staying in a spa hotel in Santa Margarita, with plenty of hotels from CA $222 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays. ### Is it cheaper to book a spa hotel in Santa Margarita with flights as part of a package deal? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package. ### Are there any unique spa experiences available in Santa Margarita? > Yes, the Rancho Santa Margarita area, adjacent to Santa Margarita, offers several unique spa experiences that blend traditional and modern wellness practices. > > > > Spa Gregorie's Day Spa & Salon in Rancho Santa Margarita provides a range of specialty massages, facials, and body treatments. This establishment also incorporates modern wellness techniques such as integrative wellness coaching and biohacking treatments like red light therapy and EMS Wave Mats. > > > > Hand & Stone Spa in Rancho Santa Margarita offers professional spa services, including heated stone massages, designed to promote deep relaxation and improved circulation. > > > > For a more immersive wellness experience, Sagrada Wellness in the broader Santa Margarita region offers yoga and hiking retreats. ### How can I save on a spa hotel in Santa Margarita with Expedia? > Members always get our best prices. Find our best Santa Margarita spa hotel deals by joining Expedia's free travel rewards program—[One Key™](https://www.expedia.ca/welcome-one-key). As a member, you can unlock instant savings and member perks when you're logged in to your account. For a spontaneous weekend retreat, discover last-minute offers. ### Can I cancel my spa hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Santa Margarita for you. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [3 Star Hotels in Edna Valley](https://www.expedia.ca/3Star-Edna-Valley-Hotels.s30-0-d553248621593965859.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Edna Valley](https://www.expedia.ca/4Star-Edna-Valley-Hotels.s40-0-d553248621593965859.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Central Coast California](https://www.expedia.ca/5Star-Central-Coast-California-Hotels.s50-0-d6055477.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Edna Valley](https://www.expedia.ca/5Star-Edna-Valley-Hotels.s50-0-d553248621593965859.Travel-Guide-Filter-Hotels) - [Hotels near Carrizo Plain National Monument](https://www.expedia.ca/Carrizo-Plain-National-Monument-Hotels.0-l553248635976370558-0.Travel-Guide-Filter-Hotels) - [Aparthotels in Central Coast California](https://www.expedia.ca/Central-Coast-California-Apart-Hotels.d6055477-aaApartHotels.Travel-Guide-Accommodation) - 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