Title: 10 Best Hotels in Santa Lucia, Syracuse for 2026 | Expedia.ca

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![The Sanctuary of the Madonna delle Lacrime was erected in memory of the miraculous lacrimation of the effigy depicting the Immaculate Heart of Mary, placed to the bedside of the spouses Lannuso at their humble home in Via degli Orti in Syracuse, in 1953.](https://images.trvl-media.com/place/4912/ebc9711a-483a-4c63-a902-49105c0eea54.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by William Keller

# Hotels in Santa Lucia, Syracuse 

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## Go beyond your typical stay in Santa Lucia

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&amenities=SPA_ON_SITE)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&travelerType=family_friendly)

Ocean view

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&amenities=OCEAN_VIEW)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&lodging=APARTMENT)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&amenities=HOT_TUB)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&amenities=POOL)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&amenities=WATER_PARK)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&amenities=PETS)

Farm

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&lodging=AGRITOURISM)

Villa

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Lucia%2C+Syracuse%2C+Sicily%2C+Italy&regionId=553248635213209885&latLong=37.071304%2C15.289151&adults=2&startDate=2025-12-22&d1=2025-12-22&endDate=2025-12-24&d2=2025-12-24&lodging=VILLA)

## Check prices for these dates

Tonight

[Dec 8 - Dec 9](https://www.expedia.ca/Hotel-Search?regionId=553248635213209885&startDate=2025-12-08&endDate=2025-12-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=553248635213209885&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635213209885&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635213209885&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Santa Lucia hotels and places to stay

![Suite](https://images.trvl-media.com/lodging/104000000/103530000/103523100/103523090/fbe2e278.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Triple Room](https://images.trvl-media.com/lodging/104000000/103530000/103523100/103523090/a8563377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite | Bathroom](https://images.trvl-media.com/lodging/104000000/103530000/103523100/103523090/cbd64090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite](https://images.trvl-media.com/lodging/104000000/103530000/103523100/103523090/4b17f7a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Palazzo Cavalieri

Santa Lucia

8.8/10

Excellent

(38)

"The location of this hotel is ideal! Directly between the train station and Ortigia. Easy walking to many different restaurants. We very much enjoyed our short stay here and the daily activities hosted by the Hotel. My only iffy thing was the tiles in the bathroom (the shower specifically) seemed a bit older and maybe not as cleanly as it could be, but all in all the room was quite nice. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Lindsay

CA $142

CA $162 total

includes taxes & fees

Dec 9 - Dec 10

[](https://www.expedia.ca/Syracuse-Hotels-Hotel-Cavalieri.h103523090.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/2465bcdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/8690ebba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/542cec6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/3000000/2980000/2974800/2974756/d745213b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grande Albergo Alfeo

Santa Lucia

8.6/10

Excellent

(651)

"The room was nice the location convenient. No view to speak of but centrally located"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Eric

[](https://www.expedia.ca/Syracuse-Hotels-Grande-Albergo-Alfeo.h2974756.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/f4662c00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor spa tub](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/f2d141d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Room](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/9785c0f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/1ee23ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Caportigia Boutique Hotel

Santa Lucia

9.4/10

Exceptional

(256)

"Fine quality hotel with exceptional service. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Peter

CA $168

CA $201 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Syracuse-Hotels-Caportigia-Boutique-Hotel.h17519019.Hotel-Information)

![Double Room, 1 King Bed, Sea View, Tower | Terrace/patio](https://images.trvl-media.com/lodging/118000000/117120000/117118700/117118661/28a61820.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, Sea View](https://images.trvl-media.com/lodging/118000000/117120000/117118700/117118661/2971ad68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/118000000/117120000/117118700/117118661/7c13b84e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/118000000/117120000/117118700/117118661/91ad9665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Miranda Boutique 

Santa Lucia

CA $263

CA $306 total

includes taxes & fees

Dec 18 - Dec 19

[](https://www.expedia.ca/Syracuse-Hotels-Casa-Miranda-Boutique.h117118661.Hotel-Information)

![Superior Triple Room, Sea View](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/43120257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/f50d20c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Triple Room, Sea View | Terrace/patio](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/e0cdb4a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/25540a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fortaleza Charme House

Santa Lucia

10/10

Exceptional

(27)

"Great central location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig

CA $221

CA $252 total

includes taxes & fees

Dec 9 - Dec 10

[](https://www.expedia.ca/Syracuse-Hotels-Fortaleza-Charme-House.h105439006.Hotel-Information)

![Double or Twin Room, Balcony, Ocean View](https://images.trvl-media.com/lodging/9000000/8380000/8376700/8376633/08fa3443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, Balcony, Ocean View](https://images.trvl-media.com/lodging/9000000/8380000/8376700/8376633/da28e6b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Triple Room, Balcony | Balcony](https://images.trvl-media.com/lodging/9000000/8380000/8376700/8376633/a1e41084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8380000/8376700/8376633/dc86ccf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### B&B Nike

Santa Lucia

8.8/10

Excellent

(75)

"Clean, good location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Salvatore

[](https://www.expedia.ca/Syracuse-Hotels-BB-Nike.h8376633.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/4000000/3100000/3091700/3091630/4c69e8c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Double or Twin Room, 1 Bedroom, Balcony, Sea View](https://images.trvl-media.com/lodging/4000000/3100000/3091700/3091630/8656c81b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/4000000/3100000/3091700/3091630/76baf5d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/4000000/3100000/3091700/3091630/a2443701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Giuggiulena Villa

Santa Lucia

10/10

Exceptional

(126)

"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $272

CA $311 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Syracuse-Hotels-Giuggiulena-Villa.h3091630.Hotel-Information)

![Water view](https://images.trvl-media.com/lodging/36000000/35370000/35360800/35360799/b9e46e77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/36000000/35370000/35360800/35360799/ce81f99e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/36000000/35370000/35360800/35360799/8da26db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Sea View](https://images.trvl-media.com/lodging/36000000/35370000/35360800/35360799/aeabb122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Re Dionisio Luxury Suites

Santa Lucia

8.8/10

Excellent

(57)

"Spacious room, dated but comfortable."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kenneth

CA $569

CA $642 total

includes taxes & fees

Dec 31 - Jan 1, 2026

[](https://www.expedia.ca/Syracuse-Hotels-Re-Dionisio-Boutique-Hotel.h35360799.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2540000/2539600/2539517/70b64e81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/3000000/2540000/2539600/2539517/de127e9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2540000/2539600/2539517/bf750551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/3000000/2540000/2539600/2539517/00aaef6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel dei Coloniali

Santa Lucia

7.4/10

Good

(166)

"Convenient location for Syracuse town, but in a scruffy area and the whole property is looking tired. Breakfast was adequate. The owner was charming and happy to help."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Rod

CA $88

CA $100 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Syracuse-Hotels-Hotel-Dei-Coloniali.h2539517.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/2000000/1140000/1133800/1133702/95edfb40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Double Room, Balcony, Sea View](https://images.trvl-media.com/lodging/2000000/1140000/1133800/1133702/f95279e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Triple Room, Balcony, Ocean View | View from room](https://images.trvl-media.com/lodging/2000000/1140000/1133800/1133702/ec86de2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/2000000/1140000/1133800/1133702/2ca740bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Mediterraneo

Santa Lucia

7.8/10

Good

(122)

"Very friendly and helpful staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

[](https://www.expedia.ca/Syracuse-Hotels-Hotel-Mediterraneo.h1133702.Hotel-Information)

![Coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/9000000/8770000/8763800/8763735/a728c4b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/9000000/8770000/8763800/8763735/44d2e27e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exclusive Apartment | Living area](https://images.trvl-media.com/lodging/9000000/8770000/8763800/8763735/bcb94a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/9000000/8770000/8763800/8763735/c554e010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nostos rooms & Apartments

Santa Lucia

9.0/10

Wonderful

(273)

"On a main thoroughfare close to Isola di Ortigia. Friendly management and helpful to me."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $87

CA $100 total

includes taxes & fees

Jan 8 - Jan 9, 2026

[](https://www.expedia.ca/Syracuse-Hotels-BB-Nostos.h8763735.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2020000/2010100/2010088/f70e005a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/3000000/2020000/2010100/2010088/e87add85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Porch](https://images.trvl-media.com/lodging/3000000/2020000/2010100/2010088/e4ffb628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2020000/2010100/2010088/327c106f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Piccolo Hotel Casa Mia

Santa Lucia

8.6/10

Excellent

(373)

"The staff is extremely nice and friendly and you feel welcome. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Florentina

[](https://www.expedia.ca/Syracuse-Hotels-Piccolo-Hotel-Casa-Mia.h2010088.Hotel-Information)

![Suite, Balcony, Sea View](https://images.trvl-media.com/lodging/3000000/2530000/2522400/2522354/c6129591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2530000/2522400/2522354/971ae922.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2530000/2522400/2522354/3adf887e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room Sea View | Terrace/patio](https://images.trvl-media.com/lodging/3000000/2530000/2522400/2522354/08289cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakkios

Santa Lucia

9.0/10

Wonderful

(62)

"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"

![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg)

Jon-Kåre

[](https://www.expedia.ca/Syracuse-Hotels-Lakkios.h2522354.Hotel-Information)

![Triple Room, Housekeeping, City View](https://images.trvl-media.com/lodging/117000000/116080000/116074600/116074546/df13dfdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double or Twin Room, Housekeeping, City View | View from room](https://images.trvl-media.com/lodging/117000000/116080000/116074600/116074546/4a43860f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/117000000/116080000/116074600/116074546/12c7eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Triple Room, Housekeeping, City View](https://images.trvl-media.com/lodging/117000000/116080000/116074600/116074546/d441e12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Agorà

Santa Lucia

10/10

Exceptional

(1)

"Carlo was great. He wanted to help in any way. The room was excellent except for Friday night music and traffic. You want to party it is near there. Would stay there again. Walkable to most places. Good restaurants near by."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bryce

CA $112

CA $128 total

includes taxes & fees

Dec 13 - Dec 14

[](https://www.expedia.ca/Syracuse-Hotels-Agora.h116074546.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8350000/8343300/8343269/328c4e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/9000000/8350000/8343300/8343269/ee712d79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Single Room | Terrace/patio](https://images.trvl-media.com/lodging/9000000/8350000/8343300/8343269/53fa88c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8350000/8343300/8343269/027f65cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Le Muse

Santa Lucia

7.4/10

Good

(71)

"The room was great and the staff was exceptionally helpful"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Henry

CA $170

CA $194 total

includes taxes & fees

Dec 19 - Dec 20

[](https://www.expedia.ca/Syracuse-Hotels-Hotel-Le-Muse.h8343269.Hotel-Information)

![Full-size fridge, oven, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/34000000/33450000/33444500/33444412/625bbc70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33450000/33444500/33444412/9d0b7c7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Room | View from room](https://images.trvl-media.com/lodging/34000000/33450000/33444500/33444412/cda7c0a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/34000000/33450000/33444500/33444412/47e24f8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gymnasium

Santa Lucia

8.8/10

Excellent

(40)

"Nice kitchen area, centrally located."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

[](https://www.expedia.ca/Syracuse-Hotels-BB-Gymnasium.h33444412.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/90000000/89290000/89289100/89289079/c137218d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/90000000/89290000/89289100/89289079/74ad7518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/90000000/89290000/89289100/89289079/ffb2814f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/90000000/89290000/89289100/89289079/3f94f6c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Calafatari B&B

Santa Lucia

10/10

Exceptional

(11)

"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carl and Lina

[](https://www.expedia.ca/Syracuse-Hotels-Calafatari.h89289079.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5030000/5020800/5020784/976bca6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5030000/5020800/5020784/392f1075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Single Room](https://images.trvl-media.com/lodging/6000000/5030000/5020800/5020784/56ed95ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/6000000/5030000/5020800/5020784/ac480855.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Populus

Santa Lucia

7.8/10

Good

(74)

"Just stay somewhere else, plain and simple."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

CA $109

CA $125 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Syracuse-Hotels-Populus.h5020784.Hotel-Information)

![Double Room](https://images.trvl-media.com/lodging/15000000/14740000/14739300/14739278/8803eb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/15000000/14740000/14739300/14739278/363b82ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Triple Room](https://images.trvl-media.com/lodging/15000000/14740000/14739300/14739278/a67f7eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Triple Room](https://images.trvl-media.com/lodging/15000000/14740000/14739300/14739278/4a9342dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### B&B Siracusa

Santa Lucia

9.0/10

Wonderful

(59)

"Good location, very modern clean accommodation."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Malcolm

CA $105

CA $120 total

includes taxes & fees

Dec 11 - Dec 12

[](https://www.expedia.ca/Syracuse-Hotels-BB-Siracusa.h14739278.Hotel-Information)

![Exclusive Room](https://images.trvl-media.com/lodging/96000000/95140000/95131100/95131096/a175585e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shared fridge](https://images.trvl-media.com/lodging/96000000/95140000/95131100/95131096/79bfc58e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room | Wardrobe](https://images.trvl-media.com/lodging/96000000/95140000/95131100/95131096/c28bdab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exclusive Room](https://images.trvl-media.com/lodging/96000000/95140000/95131100/95131096/d63eb22a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Isonzo Suites

Santa Lucia

8.4/10

Very good

(5)

"."

![Italy](https://a.travel-assets.com/egds/marks/flags/it.svg)

Gianluca

CA $103

CA $165 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/Syracuse-Hotels-Isonzo-Suites.h95131096.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-22&endDate=2025-12-23&regionId=553248635213209885&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. 

- Ortigia
- Tiche
- Neapolis
- Acradina
- Grottasanta

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87667-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Temple of Apollo showing heritage elements and building ruins](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87666-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Temple of Apollo featuring street scenes and heritage elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87663-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Temple of Apollo which includes building ruins and heritage elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87670-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Temple of Apollo featuring a ruin, street scenes and heritage elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87673-Temple-Of-Apollo.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635213212045)

![Ortigia map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:uzeaFygi%7CAwHsJ%7DG%60%40EZkEDrAuGG_AO%5Co%40e%40Pk%40%7DC_%40Qi%40TQlBd%40Z%5B%7CFgKcByCuEyDT_AXCpHfHfCCnCuANf%40%7EDPlCeCl%40qCtEyDjDl%40rDqAItCdCB%5E%60Al%40E%5Ef%40%5CjAWhBPn%40%7E%40S%3FvDv%40tBlBBpKeE%7EC%60CxDkCbAwBf%40Nq%40pDsBfEgB%7E%40cBCsDp%40%7BIxEyAtCgB%60%40%5CtEm%40iDo%40LGe%40qRjDVjC%7B%40Z%7B%40wCgEdG&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=pmNCAHUleb6hkejMUM2kmj7vEZ4=)

### Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635213212045)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635213213825)

![Tiche map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_bmaFiza%7CAm%40_%40U%7DDvAOBsEj%40sC%40kTi%40Pq%40i%40BsHgID%3FcFfEJJkLkGNA_Ag%40%40Ao%40h%40OiAcKiAq%40aVbAkBuKlBjAfAQ%5C%7D%40Us%40T%7DBs%40qA%5EKoBmCUyDaB_CgDoMp%40yCUyD%60EaC%7C%40oGjD%5BrENnC%7DAZ%5CKrBf%40%5CzMvBhKnDlLe%40xHuF%7CCN%7DBgQ%7CAKWcCbLqAHoCdBeBhVc%40nGqBnChOTjFvPkGjGp%5ClF%7ETmA%60D%7BAzIyEfC%7DDxHgJ%7EKuP%60YkWb%5CyJfKqPxJyKlAeCt%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=RYEHG0yi0IG66-wUmqK_UXNjSTQ=)

### Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635213213825)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=952515174506594304)

![Neapolis map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:e%7ChaF_ne%7CAq%40y%40QPsKkM%5DnCMLKUsDcQm%40eBQ_BsFoYzBoArBiAxAYvS%7DACuHGmSWwDbAaCvI%60B%7CGv%40I%60O%7EKt%40h%40RZpKeDdBr%40bC%60E%7ETyCjGiElCkB%60DmA%7EH%7BEhKqLlD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=etuAtkTmH-Na-zOlR4CLnA9CYgY=)

### Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=952515174506594304)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635213214634)

![Acradina map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:isnaFklf%7CAAyApAkFM%7BCVc%40r%40%5Ed%40i%40P%60%40jB%40JoCu%40Ac%40b%40k%40E%3F%5Ba%40VHkAgAYoC%60%40%7B%40gBuCaBIuA%7BAgAVoBs%40%7BAaAYNwAi%40K%3Fe%40pF%7CD%7EK%7CDxBqBxDU%60D%7D%40tCLbKnHhCH_%40_D%60%40uClDo%40%7EAfAbBmCm%40kI%60L%7BPy%40eGyDjBuCiO_FGpCoCdEqACo%40%7EAq%40p%40%7EC%60AIjCgCDRpAu%40t%40p%40%60EU%60%40eA%7E%40ItBoA%7EPbKvGiFbCvF%60D%60CtG%3F%7EAlG%7CTkJx%40iBlB%7B%40bG%7B%40kCmHrMiFZj%40hDtAShA%60A%60%40yCbRv%40zFt%40f%40_AfCLdJ%7B%40%5EQz%40%5CxAWvBzArD%3FpH_VlBqEfCkRbHUkFoCiOoGpB%7DU%5EiBzAQ%7CCcLpAVbC%7DAJ%7CBfQ%7DCOyHtFmLd%40iKoD%7BMwBg%40%5DJsB%5B%5DoC%7CAsEOkDZ%7D%40nGaE%60C&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=eCMT0Ns9gsxOpEYlI-9q1Q5b4I8=)

### Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635213214634)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635213213857)

![Grottasanta map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ejmaFmhg%7CAiCIcKoHuCMaD%7C%40yDTyBpB_L%7DDmF%7DD%5EEGi%40f%40_%40KgBd%40FRgBm%40AAeAv%40TtAiC%5EiFk%40yDlAgDUe%40%5E%5DK%7D%40d%40s%40VqDjADBoAv%40CCu%40%5EGOaA%60A%7D%40u%40uIn%40_C%7D%40sBvCwAfAgBBu%40%5CCOyBl%40uBvGwCCz%40n%40AClApAh%40rEy%40dA%7DA%60FqALcCPSNf%40LOb%40cBrAj%40LaB%60Ic%40Ba%40hCm%40dAiAt%40MbBHd%40%5D%7C%40%60%40hIwBnDRpE%7B%40dC%40%5DgDdB%5BxBb%40HvBz%40i%40Xb%40%7CDaArA%3FlEfFfIp%40fJuEBiA%5Cr%40ZG%60EkCtBMs%40x%40bBr%40%7ECgB%7EDLDXnAi%40vALnCk%40BpAc%40%5C%5C%5Ee%40PXPfBe%40KnAq%40r%40dASr%40lA%5CGI%7ECZ%3FNjCh%40Vr%40nCYlBf%40%60%40xByAGaAXNQxBh%40vCaArBf%40%7C%40IdFoBpHaAa%40RiAiDuA%5Bk%40sMhFjClHcGz%40mBz%40y%40hB%7DTjJ_BmGuG%3FaDaCcCwFwGhF_QcKuBnA_AHa%40dAaETu%40q%40qAt%40ESkCfCaAHq%40_D_Bp%40Bn%40eEpAqCnC%7EEFtChOxDkBx%40dGaLzPl%40jIcBlC_BgAmDn%40a%40tC%5E%7EC&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=JWhQvZH-Tc8NoYmsBpvws_O2oWs=)

### Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635213213857)

## Top Santa Lucia Hotel Reviews

![Algila' Ortigia Charme Hotel](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9_y.jpg)

### Algila' Ortigia Charme Hotel

10/10 Excellent

"Great location. Great service. Enjoy Ortigia!"

[](https://expedia.ca/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information)

![Palazzo Artemide - VRetreats](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/5db9500b_y.jpg)

### Palazzo Artemide - VRetreats

10/10 Excellent

"Great service……………"

[](https://expedia.ca/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information)

![Mercure Siracusa Prometeo](https://images.trvl-media.com/lodging/2000000/1540000/1538700/1538612/b09648f6_y.jpg)

### Mercure Siracusa Prometeo

10/10 Excellent

"Excellent central location. Comfortable rooms with safe and walk in shower. Great staff helpful, polite, professional and friendly. Had a very relaxing time."

[](https://expedia.ca/Syracuse-Hotels-Mercure-Siracusa-Prometeo.h1538612.Hotel-Information)

![Lanterne Magiche Ortigia](https://images.trvl-media.com/lodging/19000000/18710000/18704100/18704044/266affcc_y.jpg)

### Lanterne Magiche Ortigia

10/10 Excellent

"Wonderful room. Spacious, good amenities, comfortable bed."

[](https://expedia.ca/Syracuse-Hotels-Lanterne-Magiche-Ortigia.h18704044.Hotel-Information)

![Grand Hotel Villa Politi](https://images.trvl-media.com/lodging/2000000/1230000/1220700/1220650/73408607_y.jpg)

### Grand Hotel Villa Politi

10/10 Excellent

"Great old “grand hotel”. Beautiful property. "

[](https://expedia.ca/Syracuse-Hotels-Grand-Hotel-Villa-Politi.h1220650.Hotel-Information)

![Grand Hotel Ortigia Siracusa](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/206c3f7f_y.jpg)

### Grand Hotel Ortigia Siracusa

10/10 Excellent

"breakfast was good"

[](https://expedia.ca/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information)

![Fortaleza Charme House](https://images.trvl-media.com/lodging/106000000/105440000/105439100/105439006/43120257_y.jpg)

### Fortaleza Charme House

10/10 Excellent

"Cute hotel close to everything we wanted to see! Would definitely recommend!!"

[](https://expedia.ca/Syracuse-Hotels-Fortaleza-Charme-House.h105439006.Hotel-Information)

![Caportigia Boutique Hotel](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/f4662c00_y.jpg)

### Caportigia Boutique Hotel

10/10 Excellent

"Fine quality hotel with exceptional service. "

[](https://expedia.ca/Syracuse-Hotels-Caportigia-Boutique-Hotel.h17519019.Hotel-Information)

![Mangia's Brucoli, Sicily, Autograph Collection](https://images.trvl-media.com/lodging/2000000/1620000/1619900/1619803/93e12b57_y.jpg)

### Mangia's Brucoli, Sicily, Autograph Collection

10/10 Excellent

"Gorgeous setting, relaxing vibe, beautiful pool, great service"

[](https://expedia.ca/Augusta-Hotels-Brucoli-Village.h1619803.Hotel-Information)

## Frequently asked questions

### What is Santa Lucia like?

### Where is the best place to stay in Santa Lucia?

### How many hotels can I expect to find in Santa Lucia?

### If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

### What are the top things to see and do in Santa Lucia?

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- [Flights to Syracuse ](https://www.expedia.ca/Cheap-Flights-To-Syracuse.d4912.Travel-Guide-Flights)
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- [Lungomare di Ortigia ](https://www.expedia.ca/Lungomare-Di-Ortigia-Ortigia.d6284111.Vacation-Attraction)
- [Visit Province of Syracuse ](https://www.expedia.ca/Province-Of-Syracuse.dx6052967)
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- [Alamo Rent A Car Rental Cars in Syracuse ](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Syracuse.d4912-c6.Car-Rental-Guide-Suppliers)
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- [Syracuse Vacation Rentals ](https://www.expedia.ca/Syracuse-Vacation-Rentals.d4912.Travel-Guide-VacationRentals)

- [Things to do in Syracuse ](https://www.expedia.ca/Things-To-Do-In-Syracuse.d4912.Travel-Guide-Activities)

- [Book Hotels in Santa Lucia on Expedia.it ](https://www.expedia.it/Santa-Lucia-Siracusa-Hotel.0-n553248635213209885-0.Guida-Viaggi-Filtro-Hotel)