Title: Santa Fe Island Vacation Home Rentals from CA $165: Search Top Private Vacation Homes for Rent | Expedia.ca [Santa Fe Island Travel Guide](https://expedia.ca/Santa-Fe-Island.dx6336630)[Hotels in Santa Fe Island](https://expedia.ca/Santa-Fe-Island-Hotels.d6336630.Travel-Guide-Hotels)[Vacation Rentals in Santa Fe Island](https://expedia.ca/Santa-Fe-Island-Vacation-Rentals.d6336630.Travel-Guide-VacationRentals)[Flights to Santa Fe Island](https://expedia.ca/Cheap-Flights-To-Santa-Fe-Island.d6336630.Travel-Guide-Flights)[Santa Fe Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Fe-Island.d6336630.Car-Rental-Guide)[Santa Fe Island Vacation Packages](https://expedia.ca/Santa-Fe-Island.d6336630.Destination-Travel-Guides) ![Seal lions 😍 #aquatrove](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Elizabeth Oates # Santa Fe Island Vacation Rentals - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6336630&startDate=2025-12-19&endDate=2025-12-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6336630&startDate=2025-12-26&endDate=2025-12-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6336630&startDate=2026-01-09&endDate=2026-01-11&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6336630&startDate=2026-02-06&endDate=2026-02-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Fe Island vacation homes ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f0249e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/5b0760b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/6f52aa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f1c0fb19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos [](https://www.expedia.ca/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information) Puerto Ayora 10/10 Exceptional (1) "Nice and beautiful house to stay very impressed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $138 CA $165 total Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/910a26ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/59b60aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/6cb34f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/e5fb900f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jardin de Galápagos. [](https://www.expedia.ca/Puerto-Ayora-Hotels-Jardin-De-Galapagos.h100640217.Hotel-Information) Galápagos Islands CA $93 CA $166 total Dec 15 - Dec 16 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Jardin-De-Galapagos.h100640217.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/ebf60a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/d7cc9d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/753f38a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/46b3f49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Two Bedroom house - The Galapagos Pearl Hotel [](https://www.expedia.ca/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information) Puerto Ayora 10/10 Exceptional (1) "We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura E. CA $276 CA $343 total Dec 21 - Dec 22 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/6e3cf51a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/f20e4de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/247eabf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, books](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/9f903199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Life Two-Bedroom Galapagos Casita [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information) Puerto Ayora 10/10 Exceptional (3) "We had a great time and are grateful to John and Donna for hosting us. The casita was very comfortable and quiet. Great wifi and air conditioning for when we needed to relax. Thank you again!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Victoria K. CA $214 CA $277 total Dec 14 - Dec 15 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/1f94b12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2ad1a614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/369f220c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome, 1 Bedroom, Non Smoking, City View](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2847ed9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Galapagos [](https://www.expedia.ca/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information) Puerto Ayora 6.0/10 (1) "着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。" ![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg) アオアシカツオドリ [](https://www.expedia.ca/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/937eb7c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/89f46e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/3ba85021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121720000/121711100/121711100/ff40a829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island life Duplex great for groups [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information) Puerto Ayora, Santa Cruz Island CA $386 CA $493 total Dec 14 - Dec 15 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Duplex-Great-For-Groups.h121711100.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27®ionId=6336630&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-Island-Private-Vacation-Homes.d6336630-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-Island-Private-Vacation-Homes.d6336630-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Santa Fe Island Hotel Reviews ![Capitan Max B&B](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48_y.jpg) ### Capitan Max B&B 10/10 Excellent "Great!" [](https://expedia.ca/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Maidith Galapagos Inn](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/1dd0538f_y.jpg) ### Maidith Galapagos Inn 10/10 Excellent "This was a great stay! The hotel is so cute and the staff is top notch! The rooms were spacious, had plenty of shelving, and the bed was comfortable. The hotel is convenient, located near stores, Darwin Ave, restaurants, and bars. It is about a 10 minute walk to the pier, but they will coordinate taxis if you need it. They give you a discount to a local tour agency and restaurant. The staff is very helpful and accommodating. I skipped breakfast and told them I was going to Isabela Island and they made a to-go bag for lunch for me. Highly recommend this place!" [](https://expedia.ca/Puerto-Ayora-Hotels-Maidith-Galapagos-Inn.h88474681.Hotel-Information) ![Hotel Palace Galapagos](https://images.trvl-media.com/lodging/12000000/11060000/11050700/11050675/48760e17_y.jpg) ### Hotel Palace Galapagos 10/10 Excellent "Absolutely happy with everything!!!! My room was cleaned before I back from my day out!!! Great service! Recommend to everyone!!! Close to everything !! Loved it " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Palace-Galapagos.h11050675.Hotel-Information) ![Hotel Fiesta](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/b440b32f_y.jpg) ### Hotel Fiesta 10/10 Excellent "Clean large bright nice rooms and bathrooms with hot water. Basic breakfast is excellent. Clean towels and rooms are cleaned everyday with new fresh towels. Staff is extremely knowledgeable and helpful. 5 min walk from the main pier and downtown restaurant. Good value for price and location." [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information) ![El Barranco Galapagos](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/910f927d_y.jpg) ### El Barranco Galapagos 10/10 Excellent "This place is amazing!!! The staff was great and the amenities are top! The hot tub is open all day! Breakfast was the best I’ve had in a hotel. We will definitely recommend it to friends. We stayed at the dock house and it was unbelievable, just make sure the propane tank for the hot tub is connected when you are checking in so when you are ready to use it, you can get it going no problem … otherwise dock house is the best " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information) ![Hotel Cucuve](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/733c9cb5_y.jpg) ### Hotel Cucuve 10/10 Excellent "Best place we stayed at in Ecuador. Clean, friendly and affordable. " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) ![Hotel Ninfa](https://images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e_y.jpg) ### Hotel Ninfa 10/10 Excellent "Great, clean, and convenient place. Good location close to docks. Walkable to the Main Street. Hotel rooms clean with good service and breakfast. We stayed here two seperate times during Galapagos and would stay again. " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) ![Angermeyer Waterfront Inn](https://images.trvl-media.com/lodging/5000000/4890000/4884900/4884897/9d038793_y.jpg) ### Angermeyer Waterfront Inn 10/10 Excellent "Wonderful establishment overall. Great made to order breakfast, good service and friendly staff. The requirement of a water taxi to get to the hotel while daunting at first, is not an issue at all as they are cheap and plentiful. Our room had a great ocean view. The housekeeping and Turndown services were perfectly timed." [](https://expedia.ca/Puerto-Ayora-Hotels-Angermeyer-Waterfront-Inn.h4884897.Hotel-Information) ![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b6171efd_y.jpg) ### Hotel el descanso del Guia 10/10 Excellent "What really stood out was the exceptional customer service. Everyone was friendly, professional, and always willing to help with anything I needed. The location was perfect, and the atmosphere made my stay Monica" [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information) ## Find out more about Santa Fe Island ## Santa Fe Island Vacation Homes information | Number of reviews | 4 | | ----------------- | ----------------- | | Accommodation | 19 Vacation Homes | | Lowest Price | CA $165 | | Highest Price | CA $493 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [Baltra Hotels ](https://www.expedia.ca/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Bellavista ](https://www.expedia.ca/Bellavista-Hotels-LGBT-Friendly-Hotel.0-0-d6342722-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bellavista Hotels ](https://www.expedia.ca/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - [Apartments in Daphne Islands ](https://www.expedia.ca/Daphne-Islands-Apartments.d6336492-aaApartments.Travel-Guide-Accommodation) - [All Inclusive Resorts and in Galápagos ](https://www.expedia.ca/Destinations-In-Galapagos-All-Inclusive-Hotel.0-0-d1371-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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