Title: Book the Best Santa Cruz Southwest LUXURY Hotels - Upscale Hotels in Santa Cruz Southwest, Tucson | Expedia.ca [Santa Cruz Southwest Travel Guide](https://expedia.ca/Tucson-Santa-Cruz-Southwest.dx553248635976476534)[Vacation Rentals in Tucson](https://expedia.ca/Tucson-Vacation-Rentals.d602986.Travel-Guide-VacationRentals)[Flights to Tucson](https://expedia.ca/Cheap-Flights-To-Tucson.d602986.Travel-Guide-Flights)[Things to do in Tucson](https://expedia.ca/Things-To-Do-In-Tucson.d602986.Travel-Guide-Activities)[Santa Cruz Southwest Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz-Southwest.d553248635976476534.Car-Rental-Guide)[Santa Cruz Southwest Vacations](https://expedia.ca/Santa-Cruz-Southwest.d553248635976476534.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Santa Cruz Southwest, Tucson ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Southwest Luxury Hotels Tonight [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=553248635976476534&startDate=2025-10-13&endDate=2025-10-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976476534&startDate=2025-10-14&endDate=2025-10-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976476534&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976476534&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Cruz Southwest Luxury Hotels ## Top Santa Cruz Southwest Hotel Reviews ![Hilton Tucson East](//images.trvl-media.com/lodging/1000000/30000/24200/24200/051453d4_y.jpg) ### Hilton Tucson East 10/10 Excellent "Room was clean and comfortable. This was our first time staying at a Hilton and we were truly satisfied. We will surely stay here again when we visit Tucson." [](https://expedia.ca/Tucson-Hotels-Hilton-Tucson-East.h24200.Hotel-Information) ![3 Palms Tucson North Foothills](//images.trvl-media.com/lodging/1000000/20000/15800/15776/96d297e0_y.jpg) ### 3 Palms Tucson North Foothills 10/10 Excellent "The rooms are very spacious and the pool and spa are great. " [](https://expedia.ca/Tucson-Hotels-3-Palms-Tucson-North-Foothills.h15776.Hotel-Information) ![Sheraton Tucson Hotel and Suites](//images.trvl-media.com/lodging/1000000/10000/8800/8710/9842352c_y.jpg) ### Sheraton Tucson Hotel and Suites 10/10 Excellent "Great restaurant staff service " [](https://expedia.ca/Tucson-Hotels-Sheraton-Tucson-Hotel-And-Suites.h8710.Hotel-Information) ![Westward Look Wyndham Grand Resort and Spa](//images.trvl-media.com/lodging/1000000/30000/23100/23065/94279c3e_y.jpg) ### Westward Look Wyndham Grand Resort and Spa 10/10 Excellent "Breakfast was great as well as dinner " [](https://expedia.ca/Tucson-Hotels-Westward-Look-Wyndham-Grand-Resort-And-Spa.h23065.Hotel-Information) ![Desert Diamond Casino & Hotel](//images.trvl-media.com/lodging/2000000/1780000/1777700/1777624/b9366793_y.jpg) ### Desert Diamond Casino & Hotel 10/10 Excellent "I’ve stayed in many places in Tucson. I will definitely be coming back to this place. Great environment great staff. Everything was perfect." [](https://expedia.ca/Tucson-Hotels-Desert-Diamond-Casino-Hotel.h1777624.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Tucson Airport](//images.trvl-media.com/lodging/1000000/50000/41500/41411/a99345d6_y.jpg) ### La Quinta Inn & Suites by Wyndham Tucson Airport 10/10 Excellent "The staff was friendly and helpful. The rooms were nice. The beds were comfortable. The pool area was clean with comfortable seating. "Potatoes "with the eggs and sausage would be a nice addition for breakfast. " [](https://expedia.ca/Tucson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tucson-Airport.h41411.Hotel-Information) ![Lodge on the Desert](//images.trvl-media.com/lodging/1000000/20000/17300/17279/5dc25c26_y.jpg) ### Lodge on the Desert 10/10 Excellent "It is a beautiful property, with lovely grounds. There is a restaurant on sight that has decent food. There are lots of other restaurants close by. " [](https://expedia.ca/Tucson-Hotels-Lodge-On-The-Desert.h17279.Hotel-Information) ![Casino Del Sol Resort](//images.trvl-media.com/lodging/5000000/4440000/4432300/4432250/7c559143_y.jpg) ### Casino Del Sol Resort 10/10 Excellent "Clean room" [](https://expedia.ca/Tucson-Hotels-Casino-Del-Sol-Resort.h4432250.Hotel-Information) ![Loews Ventana Canyon Resort](//images.trvl-media.com/lodging/1000000/20000/11700/11605/adf141a3_y.jpg) ### Loews Ventana Canyon Resort 10/10 Excellent "Everything was good " [](https://expedia.ca/Tucson-Hotels-Loews-Ventana-Canyon-Resort.h11605.Hotel-Information) ## Frequently asked questions ### Are you looking for a luxury hotel for your stay in Santa Cruz Southwest? > Use Expedia to arrange your flight to Tucson International Airport (TUS) airport or Tucson, AZ (AVW-Marana Regional) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want a posh hotel that has fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Santa Cruz Southwest has to offer. ### What's there to see and do in Santa Cruz Southwest? > Take in the sights and attractions that Santa Cruz Southwest offers with a visit to Tuscon Spectrum, Tucson Museum of Art, and Fox Theatre. 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