Title: Book the Best HISTORIC Hotels in Santa Cruz Island in 2025 | Expedia.ca [Santa Cruz Island Travel Guide](https://expedia.ca/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Vacation-Rentals.d6053670.Travel-Guide-VacationRentals)[Flights to Santa Cruz Island](https://expedia.ca/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.ca/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz-Island.d6053670.Car-Rental-Guide)[Santa Cruz Island Vacation Packages](https://expedia.ca/Santa-Cruz-Island.d6053670.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/04d5e478ee175ffd174b1e23d51916f4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Historic Hotels in Santa Cruz Island ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Island Historic Hotels Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-18&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-19&endDate=2025-10-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Cruz Island Historic Hotels ![Exterior](https://images.trvl-media.com/lodging/67000000/66200000/66195500/66195420/e4439d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66200000/66195500/66195420/d53c3e4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/67000000/66200000/66195500/66195420/1c80b434.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/67000000/66200000/66195500/66195420/4b08bbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lonesome George Ecolodge 2 Puerto Ayora 10/10 Exceptional (1) "Aaron and Victor were fantastic hosts! Victor even went to the store to make tea for two of our group who were ill. Staying at the Lonesome George is like living in a beautiful treehouse. Photos truly don't do it justice! We would definitely go back! " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Casandra F. CA $140 CA $293 total Oct 28 - Oct 29 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Lonesome-George-Ecolodge-2.h66195420.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/6e3cf51a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/247eabf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/84bd8893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, books](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/9f903199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Life Two-Bedroom Galapagos Casita Puerto Ayora 10/10 Exceptional (3) "We had a great time and are grateful to John and Donna for hosting us. The casita was very comfortable and quiet. Great wifi and air conditioning for when we needed to relax. Thank you again!" ![](https://a.travel-assets.com/egds/marks/flags/ca.svg) Victoria K. CA $217 CA $278 total Oct 25 - Oct 26 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/40000000/39890000/39885000/39884978/7afe4884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39890000/39885000/39884978/d2dc07c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39890000/39885000/39884978/8c8ed24d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39890000/39885000/39884978/c5071fc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The lonely George Ecolodge Puerto Ayora 10/10 Exceptional (1) "We all (group of 8) LOVED this place! Super fun atmosphere and furnishings, very nice rooms, great location. Victor and Aaron were super helpful with rides for our big group and info about the area. Wish we had more time to hang out here - excellent vibe." ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly T. CA $701 CA $892 total Oct 20 - Oct 21 [](https://www.expedia.ca/Puerto-Ayora-Hotels-The-Lonely-George-Ecolodge.h39884978.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02®ionId=6053670&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Cruz Island Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Santa Fe Island](https://www.expedia.ca/5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels) - [Baltra Hotels](https://www.expedia.ca/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Bellavista](https://www.expedia.ca/Bellavista-Hotels-LGBT-Friendly-Hotel.0-0-d6342722-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bellavista Hotels](https://www.expedia.ca/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - [Apartments in Daphne Islands](https://www.expedia.ca/Daphne-Islands-Apartments.d6336492-aaApartments.Travel-Guide-Accommodation) - [All Inclusive Resorts and in Galápagos](https://www.expedia.ca/Destinations-In-Galapagos-All-Inclusive-Hotel.0-0-d1371-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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