Title: Book the Best BUSINESS Hotels in Santa Cruz Island in 2025 | Expedia.ca [Santa Cruz Island Travel Guide](https://expedia.ca/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Vacation-Rentals.d6053670.Travel-Guide-VacationRentals)[Flights to Santa Cruz Island](https://expedia.ca/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.ca/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz-Island.d6053670.Car-Rental-Guide)[Santa Cruz Island Vacation Packages](https://expedia.ca/Santa-Cruz-Island.d6053670.Destination-Travel-Guides) ![Galapagos Marine Iguana walking and swimming on Tortuga bay. Marine iguanas on beach on Santa Cruz Island, Galapagos Islands. Animals, wildlife and amazing nature in Ecuador, South America](https://images.trvl-media.com/place/6053670/54bcca80-11e8-424a-9353-2c1a8014c5d5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Santa Cruz Island - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Island Business Hotels Tonight [Nov 25 - Nov 26](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-11-25&endDate=2025-11-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Nov 26 - Nov 27](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-11-26&endDate=2025-11-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Santa Cruz Island Business Hotels ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/215f955b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Villa, 1 King Bed | View from room](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/dd75115c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/67b1e811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/w3839h2147x0y4-4f4fb150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Palm Galapagos, Curio Collection Hotel by Hilton Santa Rosa 9.2/10 Wonderful (52) "The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat. The facilities were very nice, and cleaned by friendly staff. The property grounds were serene and lovely. We thoroughly enjoyed our visit and would definitely choose the Royal Palms again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laureen CA $346 CA $381 total Dec 20 - Dec 21 [](https://www.expedia.ca/Santa-Rosa-Hotels-The-Royal-Palm-Hotel.h12535025.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/b5627025.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Bathroom](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/e94fe441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/64e7ee10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capitan Max B&B Puerto Ayora 9.8/10 Exceptional (191) "Max is the owner, he is a great host!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wenhaw CA $109 CA $109 total Nov 29 - Nov 30 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information) ![Family Room, 2 Bedrooms](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b6171efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/35a5af80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/62a8d5b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/5d600382.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel el descanso del Guia Puerto Ayora 8.8/10 Excellent (172) "Beautiful and spacious family room. Good breakfast and the staff is courteous. I highly recommend this hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susanna CA $78 CA $78 total Dec 2 - Dec 3 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/a7defe75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | Bathroom](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/09b4fe48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine, ocean views ](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/4a332d25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blu Galapagos Sustainable Waterfront Lodge Puerto Ayora 8.8/10 Excellent (121) "We had a great stay at Blu Galapagos. Loved the location and our room was perfect - Great view, well maintained and had a king bed. Even if the description says queen bed and the picture looks like a king, you can trust the picture. Morning breakfast with iguanas and seals, and all day Galapagos coffee availability made this stay special. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doreen CA $248 CA $273 total Dec 7 - Dec 8 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/15773cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/7411fddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/a0cfc072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, free minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4470000/4460600/4460518/777e735d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Solymar Puerto Ayora 7.8/10 Good (59) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) VISHAL CA $296 CA $326 total Dec 2 - Dec 3 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Hotel-Solymar.h4460518.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/3eff65ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/f3ace51e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden view](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/6c9aea3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/15000000/14740000/14734400/14734307/27568355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suymar Ecolodge Galapagos Bella Vista 9.0/10 Wonderful (14) "Incredible stay - would highly recommend this to anyone looking to stay a little out of the port area but not too far" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Porcia CA $102 CA $137 total Nov 28 - Nov 29 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Suymar-Ecolodge-Galapagos.h14734307.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/ecbf00ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Duplex](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/11c8c7ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Duplex | View from room](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/5dea777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/2f16a828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ikala Galapagos Hotel Puerto Ayora 9.6/10 Exceptional (126) "Nice clean hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marco CA $310 CA $341 total Dec 14 - Dec 15 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/2e4ce3f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/2a617ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/27cdb9cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, Ensuite](https://images.trvl-media.com/lodging/17000000/16770000/16761000/16760931/243ac55e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Deja Vu Puerto Ayora 7.6/10 Good (28) "excellent service, the staff is very friendly 🙂 good location, you can walk to the main street" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Danaee [](https://www.expedia.ca/Puerto-Ayora-Hotels-HOTEL-DEJA-VU.h16760931.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/b6818c91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 2 Bedrooms, Garden View | Private kitchen](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/a94dbde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 2 Bedrooms, Garden View](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/460a2fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17520000/17516800/17516766/b42c7514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lava House Hostal Puerto Ayora 9.4/10 Exceptional (51) "Friendly, quiet, excellent service and accommodations. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane [](https://www.expedia.ca/Puerto-Ayora-Hotels-Lava-House-Hostal.h17516766.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/6a115ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/c6bdf659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/1f7f739a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/ec05e137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galapagos Verde Azul Puerto Ayora 8.4/10 Very good (46) "The staff were very friendly. The pool and hammocks were an added bonus, it was so nice to spend an afternoon or evening relaxing by the pool. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anita [](https://www.expedia.ca/Puerto-Ayora-Hotels-Galapagos-Verde-Azul.h9577577.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11®ionId=6053670&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_6053670) ## Top Santa Cruz Island Hotel Reviews ![Hotel el descanso del Guia](https://images.trvl-media.com/lodging/18000000/17530000/17525300/17525206/b6171efd_y.jpg) ### Hotel el descanso del Guia 10/10 Excellent "What really stood out was the exceptional customer service. Everyone was friendly, professional, and always willing to help with anything I needed. The location was perfect, and the atmosphere made my stay Monica" [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-El-Descanso-Del-Guia.h17525206.Hotel-Information) ![Royal Palm Galapagos, Curio Collection Hotel by Hilton](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/215f955b_y.jpg) ### Royal Palm Galapagos, Curio Collection Hotel by Hilton 10/10 Excellent "The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat. The facilities were very nice, and cleaned by friendly staff. The property grounds were serene and lovely. We thoroughly enjoyed our visit and would definitely choose the Royal Palms again." [](https://expedia.ca/Santa-Rosa-Hotels-The-Royal-Palm-Hotel.h12535025.Hotel-Information) ![Finch Bay Galapagos Hotel](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762_y.jpg) ### Finch Bay Galapagos Hotel 10/10 Excellent "Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!" 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