Find Adults Only Resorts & Hotels in Santa Cruz from CA $56

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Top Adults only hotels in Santa Cruz

Swissôtel Santa Cruz De La Sierra
4.5 out of 5
5to anillo Avenida La Salle # 4500, Santa Cruz
The price is CA $181 per night from Aug 26 to Aug 27
CA $181
CA $181 total
Aug 26 - Aug 27
9.2/10 Wonderful! (77 reviews)
Great night at the Swissotel
"It was a great one-night stay at the Santa Cruz Swissôtel. The hotel was impecable, service excellent, and the staff very friendly and professional. We shall return to this hotel in the future."

Reviewed on Jul. 14, 2025

Swissôtel Santa Cruz De La Sierra
Novotel Santa Cruz De La Sierra
5 out of 5
AV ROCA CORONADO 901, ENTRE TERCER Y CUARTO ANILLO, Santa Cruz
The price is CA $175 per night from Aug 26 to Aug 27
CA $175
CA $175 total
Aug 26 - Aug 27
9/10 Wonderful! (95 reviews)
"The best place , best workers"

Reviewed on Apr. 20, 2025

Novotel Santa Cruz De La Sierra
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 out of 5
San Martin Avenue Esq Street E - E, Santa Cruz
The price is CA $130 per night from Aug 24 to Aug 25
CA $130
CA $130 total
Aug 24 - Aug 25
9/10 Wonderful! (248 reviews)
"Nice hotel"

Reviewed on Aug. 15, 2025

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hotel Cortez
3.5 out of 5
Av. Cristobal de Mendoza 280, Santa Cruz
The price is CA $140 per night from Aug 22 to Aug 23
CA $140
CA $140 total
Aug 22 - Aug 23
9/10 Wonderful! (111 reviews)
"The staff and property are second to none!"

Reviewed on Jun. 14, 2025

Hotel Cortez
Marriott Santa Cruz de la Sierra Hotel
5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is CA $165 per night from Aug 29 to Aug 30
CA $165
CA $165 total
Aug 29 - Aug 30
9/10 Wonderful! (191 reviews)
"all"

Reviewed on Jun. 5, 2025

Marriott Santa Cruz de la Sierra Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 out of 5
Ave. San Martin, #455, Santa Cruz
The price is CA $182 per night from Sep 11 to Sep 12
CA $182
CA $182 total
Sep 11 - Sep 12
8.8/10 Excellent! (322 reviews)
"Always an amazing hotel"

Reviewed on Jun. 21, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Camino Real Hotel
4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is CA $194 per night from Sep 15 to Sep 16
CA $194
CA $194 total
Sep 15 - Sep 16
8.8/10 Excellent! (396 reviews)
Best amenities
"Best amenities in a hotel , but need some upgrades"

Reviewed on Jul. 16, 2025

Camino Real Hotel
Sun Hotel
3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
The price is CA $135 per night from Aug 22 to Aug 23
CA $135
CA $135 total
Aug 22 - Aug 23
8.2/10 Very Good! (311 reviews)
"Staff are friendly and helpful! Great landing spot after a long flight (it’s just 5 mins from airport)."

Reviewed on Jul. 7, 2025

Sun Hotel
Hotel LP Santa Cruz Centro
3 out of 5
Av.Ejercito Nacional 290, (frente Stadium Tahuichi), Santa Cruz
The price is CA $56 per night from Aug 27 to Aug 28
CA $56
CA $56 total
Aug 27 - Aug 28
7.8/10 Good! (280 reviews)
"Clean, friendly staff"

Reviewed on Jun. 2, 2024

Hotel LP Santa Cruz Centro
Casa Vida
3.5 out of 5
Condominio Club Campestre, Kilometro 13 doble via La Guardia, Santa Cruz, Santa
The price is CA $131 per night from Aug 22 to Aug 23
CA $131
CA $131 total
Aug 22 - Aug 23
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

Reviewed on Sep. 28, 2017

Casa Vida
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How can I find the best adults only resorts in Santa Cruz?

Adults only resorts are easy to find by sorting your search results. Choose guest and star rating, add amenity filters, arrange by budget or price. In just a few clicks, you can explore fantastic Santa Cruz adults only resorts with the pools, hot tubs, spas, and the relaxation you crave.

How much does a Santa Cruz adults only hotel cost?

Santa Cruz adults only resorts start at just CA $56 per night. For luxury resorts, prices go up to . Prices and availability are subject to change. Additional terms may apply.

When is the best time to go to a Santa Cruz adults only hotel?

When you’re celebrating an anniversary, birthday, or good old St. Valentine, every time is a good time for a romantic retreat. If you’d like to avoid the crowds, book outside the popular months of .

How can I book an adults only all-inclusive resort in Santa Cruz?

After entering your travel dates, just select the all-inclusive filter and your search results deliver every tempting getaway and the best available accommodation. All you need to do is choose your favourite … which is less easy!

Can I book an adults only Santa Cruz all-inclusive resort with airfare?

Yes, you can book flights at the same time as your all-inclusive getaway! And when you bundle flights, accommodation, and even car rental, you often save even more money with Expedia.

What amenities can I expect from adults only Santa Cruz luxury resorts?

Adults only hotels in Santa Cruz speak your love language. Maybe you’re all about the spa life. Maybe holding hands and drinking cocktails by the pool is more your thing. Maybe a candlelit feast in the finest restaurant floats your boat. Use our amenity filters to find your perfect match.

What are some great things to do in Santa Cruz for adults only?

Make your adults only escape exactly what you want it to be. Hit the hiking and biking trails or mooch around the local attractions, join local excursions, or share evenings of cocktails, sunsets, and giggles. Sometimes the best thing to do is… nothing. Just find yourself a relaxing escape and embrace the peace and quiet.

How can I find the cheapest adults only resorts in Santa Cruz?

Sort your search results by price or filter by budget to find the best deals your wallet will love.

Do adults-only hotels in Santa Cruz offer free cancellation?

You can find flexible and free cancellation options as well as book now, pay later plans with Expedia. The details vary between resorts, so it’s always best to check before you book.

Why should I book my adults-only resort in Santa Cruz with Expedia?

At Expedia, we have incredible deals and the support to give you peace of mind in your booking. Our vast selection and simple search features make it easy to build and book your dream adults only vacation in minutes.

Top Santa Cruz Hotel Reviews