Title: Book the Best BUSINESS Hotels in Santa Clara in 2025 | Expedia.ca [Vacation Rentals in Oakland](https://expedia.ca/Oakland-Vacation-Rentals.d601762.Travel-Guide-VacationRentals)[Flights to Oakland](https://expedia.ca/Cheap-Flights-To-Oakland.d601762.Travel-Guide-Flights)[Things to do in Oakland](https://expedia.ca/Things-To-Do-In-Oakland.d601762.Travel-Guide-Activities)[Santa Clara Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Clara.d553248635976469165.Car-Rental-Guide)[Santa Clara Vacations](https://expedia.ca/Santa-Clara.d553248635976469165.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Santa Clara, CA ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Clara Business Hotels Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976469165&startDate=2025-10-18&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=553248635976469165&startDate=2025-10-19&endDate=2025-10-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976469165&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976469165&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Santa Clara Business Hotels ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/23200/23140/b8dc6d3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/30000/23200/23140/2ebabf1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23200/23140/980d7efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/30000/23200/23140/a6cb4dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Inn of Hayward Santa Clara 7.8/10 Good (1018) "The beds were very comfortable sleeping. Would stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $121 CA $138 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Oakland-Hotels-Best-Western-Plus-Inn-Of-Hayward.h23140.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14500/14451/42c7dbc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/14500/14451/7e37f2cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/20000/14500/14451/13b65c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Elevator](https://images.trvl-media.com/lodging/1000000/20000/14500/14451/a77f1744.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### King George Hotel Union Square 8.6/10 Excellent (2082) "Great staff, great location, comfortable room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $112 CA $153 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Francisco-Hotels-King-George-Hotel.h14451.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/49e7095c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/17458474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/588fe135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chancellor Hotel on Union Square Union Square 9.4/10 Exceptional (2987) "Great Location!!, clean rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vahe CA $142 CA $167 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/060ec935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/d655bded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/1ac737fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/1000000/20000/11800/11793/3960290f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pickwick Hotel Downtown San Francisco 7.8/10 Good (1009) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Orlando CA $122 CA $144 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/San-Francisco-Hotels-The-Pickwick-Hotel.h11793.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/74bf4ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/51c31a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/48e843dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed with Sofa bed | Living room](https://images.trvl-media.com/lodging/1000000/10000/4800/4705/a9e1104a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Francisco Airport Millbrae 8.8/10 Excellent (2064) "Easy to stay here, great staff, always helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald CA $168 CA $234 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/San-Francisco-Hotels-The-Westin-San-Francisco-Airport.h4705.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/500/491/5e565895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/500/491/76fc74a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/500/491/fd911583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with cable channels, TV, pay movies](https://images.trvl-media.com/lodging/1000000/10000/500/491/73838018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Francisco Downtown SOMA Downtown San Francisco 9.4/10 Exceptional (1307) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eliran CA $220 CA $315 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Francisco-Hotels-The-Park-Central-San-Francisco-Hyatt-Affiliated-Hotel.h491.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/71a1e5ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/b9652b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/cbb2553d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/910000/902100/902027/5d60bf4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Aluxor SFO San Bruno 8.6/10 Excellent (2398) "Good location, comfortable stay, nice staff, we will choose this hotel again" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sharon CA $114 CA $139 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Aluxor-SFO.h902027.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/7d695984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed, Kitchenette (with Terrace)](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/acf84b9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/4c4de4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel in San Francisco Downtown San Francisco 8.8/10 Excellent (2674) "Great location clean room super nice staff ☺️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Prakash CA $146 CA $172 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Outdoor pool, cabanas (surcharge), sun loungers](https://images.trvl-media.com/lodging/1000000/10000/4400/4313/d40e00b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Balcony](https://images.trvl-media.com/lodging/1000000/10000/4400/4313/03d356b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4400/4313/60348175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/4400/4313/7ee63554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Santa Clara Santa Clara 9.0/10 Wonderful (1019) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ethel CA $195 CA $230 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Santa-Clara-Hotels-Hyatt-Regency-Santa-Clara.h4313.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7635/062e9dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7635/6553e455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/7700/7635/76976cda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/10000/7700/7635/2ef696cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Grosvenor Airport Hotel South San Francisco 8.4/10 Very good (1643) "Good for a short stay. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Joennie Catrine Hutchins CA $128 CA $151 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Francisco-Hotels-Best-Western-Plus-Grosvenor-Airport-Hotel.h7635.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02®ionId=553248635976469165&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Clara Hotel Reviews ## Explore a world of travel with Expedia - Lodging - More ways to book - [Hotels with Kitchenettes in Ashland](https://www.expedia.ca/Ashland-Oakland-Hotels-Hotels-With-Kitchenettes.0-n177699-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Ashland](https://www.expedia.ca/Ashland-Oakland-Hotels-Pet-Friendly-Hotel.0-n177699-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Green Hotels in Bay Area](https://www.expedia.ca/Bay-Area-Hotels-Green-Sustainable.0-0-d6056043-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Historic Hotels in Bay Area](https://www.expedia.ca/Bay-Area-Hotels-Historic-Hotel.0-0-d6056043-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Bay Area](https://www.expedia.ca/Bay-Area-Hotels-Mountain-Hotels.0-0-d6056043-tMountainHotels.Travel-Guide-Filter-Hotels) - 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[Hotels & Resorts for Couples in Hayward](https://www.expedia.ca/Hayward-Hotels-Couples-Resorts-Hotels.0-0-d7766-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Hayward](https://www.expedia.ca/Hayward-Hotels-Hotel-With-Early-Check-In.0-0-d7766-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Balconies in Hayward](https://www.expedia.ca/Hayward-Hotels-Hotels-With-Balconies.0-0-d7766-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Hayward](https://www.expedia.ca/Hayward-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d7766-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Hayward](https://www.expedia.ca/Hayward-Hotels-Hotels-With-Hot-Tubs.0-0-d7766-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Hayward](https://www.expedia.ca/Hayward-Hotels-Hotels-With-Kitchenettes.0-0-d7766-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Hayward](https://www.expedia.ca/Hayward-Hotels-Hotels-With-Smoking-Rooms.0-0-d7766-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - 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[Family Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Family-Hotel.0-0-d506142-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Historic-Hotel.0-0-d506142-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Hotel-With-Pool.0-0-d506142-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-LGBT-Friendly-Hotel.0-0-d506142-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Luxury-Hotel.0-0-d506142-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Pet-Friendly-Hotel.0-0-d506142-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Treasure Island](https://www.expedia.ca/Treasure-Island-Hotels-Ski-Hotel.0-0-d506142-tSkiHotel.Travel-Guide-Filter-Hotels) - 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