Title: Hotels by Independent in Sanibel Isles from CA $134 | Expedia.ca [Sanibel Isles Travel Guide](https://expedia.ca/Sanibel-Sanibel-Isles.dx553248635976477245)[Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanibel Isles Car Rentals](https://expedia.ca/Car-Rentals-In-Sanibel-Isles.d553248635976477245.Car-Rental-Guide)[Sanibel Isles Vacations](https://expedia.ca/Sanibel-Isles.d553248635976477245.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/6748f9f3d5a0dfbe5d878db6bfe88052.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Independent in Sanibel Isles from CA $134 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=553248635976477245&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976477245&startDate=2025-11-03&endDate=2025-11-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976477245&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976477245&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sanibel Isles Independent Hotels ![Suite with King Bed, Beachfront, Balcony | Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/767ba460.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/2e8856cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/1808ce0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort Fort Myers Beach 8.8/10 Excellent (1027) "All around great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $240 CA $299 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/1051a5d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/0153ec95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/b4312f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Beach Resort Fort Myers Fort Myers Beach 9.0/10 Wonderful (1588) "Beautiful property, excellent food and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $203 CA $297 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/7c494168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/10e34bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach volleyball](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/01798210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch TV with cable channels, DVD player, MP3 dock](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/92868fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Vacation Club at Coconut Cove, Bonita Springs Bonita Springs 9.2/10 Wonderful (685) "great trip and great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annamarie CA $172 CA $247 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Bonita-Springs-Hotels-Hyatt-Vacation-Club-At-Coconut-Cove.h991114.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/167b1a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 Bedroom Captiva Villa,1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/435d58a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/82b672d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pink Shell Beach Resort and Marina Fort Myers Beach 9.4/10 Exceptional (1135) "Great breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Betty CA $286 CA $412 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/a9620a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/7d170878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/bb6d486e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/50000/40900/40858/a0f722c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Trianon Bonita Bay Bonita Bay 9.2/10 Wonderful (1714) "Great location , very nice place , good restaurants" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JOSE R CA $145 CA $162 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Naples-Hotels-Trianon-Bonita-Bay.h40858.Hotel-Information) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/35893057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 Bedroom | Private kitchen](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/4ab0ecca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Junior Suite | Private kitchen](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/42fc8cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lighthouse Resort Inn & Suites Fort Myers Beach 8.6/10 Excellent (1522) "Their tiky bard is the best " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra CA $140 CA $184 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Apartment, Multiple Beds, Partial Ocean View | Beach/ocean view](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/fb0b7d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 Queen Bed, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/96081da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/ee4ac5cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/b348cef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Edison Beach House Fort Myers Beach 9.4/10 Exceptional (1544) "All around great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $269 CA $342 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Fort-Myers-Hotels-Edison-Beach-House.h11753200.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/faba246e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/23e15eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/cda8d432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/1b9c29fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dolphin Key Resort Caloosahatchee 8.8/10 Excellent (1188) "We have stayed here a few times and they never disappoint. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $140 CA $156 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Fort-Myers-Hotels-Dolphin-Key-Resort.h1632691.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/0be36f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/a06607fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/a638e8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/98f0aac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Allure Suites McGregor 7.6/10 Good (1005) "Was clean staff was very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard J CA $120 CA $134 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/55e96d4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/09cc3103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/0f55ab5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 2 Bedrooms, Balcony, Partial Ocean View | Private kitchen](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/7fccca0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Inn East End 9.0/10 Wonderful (1004) "The reception was welcoming and the room we stayed in was excellent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $394 CA $521 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Inn.h40711.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=553248635976477245&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanibel-Isles-Sanibel-Hotels-Independent.0-n553248635976477245-0--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanibel-Isles-Sanibel-Hotels-Independent.0-n553248635976477245-0--bIndependent.Travel-Guide-Filter-Hotels) ## Top Sanibel Isles Hotel Reviews ![Lani Kai Beachfront Resort](//images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "Nice remodeled room." [](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Pink Shell Beach Resort and Marina](//images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "I comeback next year" [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Trianon Bonita Bay](//images.trvl-media.com/lodging/1000000/50000/40900/40858/a9620a82_y.jpg) ### Trianon Bonita Bay 10/10 Excellent "Just a very nice place." [](https://expedia.ca/Naples-Hotels-Trianon-Bonita-Bay.h40858.Hotel-Information) ![DiamondHead Beach Resort](//images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "Easy check in , clean and beautiful view. " [](https://expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park](//images.trvl-media.com/lodging/1000000/800000/798500/798422/16c0566c_y.jpg) ### Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park 10/10 Excellent "Marie was a sweetheart. She took care of breakfast but so much more. She was willing to help with whatever and so kind and friendly. The front desk was mostly virtual but Marie was always available it seemed" [](https://expedia.ca/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) ![Sanibel Island Beach Resort](//images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "The property was clean and well maintained. The staff was all very friendly and helpful. The restaurant and tiki bar food and drinks were good. " [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Doubletree by Hilton Fort Myers at Bell Tower Shops](//images.trvl-media.com/lodging/1000000/20000/12400/12375/704cf90c_y.jpg) ### Doubletree by Hilton Fort Myers at Bell Tower Shops 10/10 Excellent "Excellent all around " [](https://expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ![Hyatt Vacation Club at Coconut Cove, Bonita Springs](//images.trvl-media.com/lodging/1000000/1000000/991200/991114/7c494168_y.jpg) ### Hyatt Vacation Club at Coconut Cove, Bonita Springs 10/10 Excellent "Beautiful….but too much construction going on around the area." [](https://expedia.ca/Bonita-Springs-Hotels-Hyatt-Vacation-Club-At-Coconut-Cove.h991114.Hotel-Information) ![Embassy Suites by Hilton Fort Myers Estero](//images.trvl-media.com/lodging/2000000/1320000/1312700/1312669/40e94d44_y.jpg) ### Embassy Suites by Hilton Fort Myers Estero 10/10 Excellent "The room was nice and clean, the happy hour was great, and the breakfast was awesome. All the staff were great and friendly." [](https://expedia.ca/Fort-Myers-Hotels-Embassy-Suites-By-Hilton-Fort-Myers-Estero.h1312669.Hotel-Information) ## Find out more about Sanibel Isles ## Sanibel Isles Hotels Guide Expedia.ca offers a selection of 15060 hotels in Sanibel Isles. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Sanibel Isles. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Sanibel Isles neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Sanibel Isles, Sanibel now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [5 Star Hotels in Sanibel](https://www.expedia.ca/5Star-Sanibel-Hotels.s50-0-d9791.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Bonita Bay](https://www.expedia.ca/Bonita-Bay-Bonita-Springs-Hotels-La-Quinta-Inn-Suites.0-n553248635976470574-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Bonita Shores](https://www.expedia.ca/Bonita-Shores-Bonita-Springs-Hotels-La-Quinta-Inn-Suites.0-n553248635976474586-0--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Bonita Springs](https://www.expedia.ca/Bonita-Springs-Hotels-Best-Western.0-0-d6403--bBestWestern.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Bonita Springs](https://www.expedia.ca/Bonita-Springs-Hotels-Hilton-Hotels.0-0-d6403--bHiltonHotels.Travel-Guide-Filter-Hotels) - 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