Title: The 10 Best Hotels Near Sanford USD Medical Center, Sioux Falls from CA $76 | Expedia.ca [Sioux Falls Travel Guide](https://expedia.ca/Sioux-Falls.dx6059512)[Vacation Rentals in Sioux Falls](https://expedia.ca/Sioux-Falls-Vacation-Rentals.d6059512.Travel-Guide-VacationRentals)[Flights to Sioux Falls](https://expedia.ca/Cheap-Flights-To-Sioux-Falls.d6059512.Travel-Guide-Flights)[Sanford USD Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Sanford-USD-Medical-Center.d553248621563219370.Car-Rental-Guide)[Sanford USD Medical Center Vacations](https://expedia.ca/Sanford-USD-Medical-Center-Sioux-Falls.d553248621563219370.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Sanford USD Medical Center, Sioux Falls from CA $76 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 26 - Nov 27](https://www.expedia.ca/Hotel-Search?regionId=553248621563219370&startDate=2025-11-26&endDate=2025-11-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 27 - Nov 28](https://www.expedia.ca/Hotel-Search?regionId=553248621563219370&startDate=2025-11-27&endDate=2025-11-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248621563219370&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248621563219370&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Sanford USD Medical Center ![Interior detail](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/edd573eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/31b10812.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/93b8eb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/831b0f67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel On Phillips Downtown Sioux Falls, 1.8 km from Sanford USD Medical Center 9.6/10 Exceptional (1285) "Very clean, beautiful hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlie [](https://www.expedia.ca/Sioux-Falls-Hotels-Hotel-On-Phillips.h36447711.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/4e13e753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/4e8d1af3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/d22edaaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/dfaa8fa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clubhouse Hotel Suites Sioux Falls Mall District, 2.9 km from Sanford USD Medical Center 9.6/10 Exceptional (1007) "Rooms were great!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $202 CA $242 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Sioux-Falls-Hotels-Clubhouse-Hotel-Suites-Sioux-Falls.h1100190.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9020000/9011900/9011875/10270e0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LCD TV](https://images.trvl-media.com/lodging/10000000/9020000/9011900/9011875/0da5ea75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/10000000/9020000/9011900/9011875/4fdf14cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/10000000/9020000/9011900/9011875/7ff68e14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Sioux Falls/Sanford Medical Center University Heights, 0.1 km from Sanford USD Medical Center 9.4/10 Exceptional (577) "Clean room, staff very helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacy CA $158 CA $176 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Sioux-Falls-Hotels-Home2-Suites-By-Hilton-Sioux-FallsSanford-Medical-Center.h9011875.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/4a36c889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/2f8dce6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/05f2adce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/bbd4aa0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Canopy By Hilton Sioux Falls Downtown Downtown Sioux Falls, 2.4 km from Sanford USD Medical Center 9.4/10 Exceptional (150) "The room was large with nice views and very clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorraine CA $195 CA $223 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Sioux-Falls-Hotels-Canopy-By-Hilton-Sioux-Falls-Downtown.h104094801.Hotel-Information) ![Presidential Suite, 1 King Bed, Jetted Tub (Balcony) | Living area](https://images.trvl-media.com/lodging/7000000/6410000/6404700/6404700/31e53656.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6410000/6404700/6404700/8fd379c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/7000000/6410000/6404700/6404700/515d74f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/7000000/6410000/6404700/6404700/43a47820.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Sioux Falls Downtown Downtown Sioux Falls, 2 km from Sanford USD Medical Center 9.0/10 Wonderful (878) "Under construction but staff adapted and accommodated very well. Room was clean and quiet. Perfect location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $148 CA $171 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Sioux-Falls-Hotels-Hilton-Garden-Inn-Sioux-Falls-Downtown.h6404700.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/46000000/45040000/45035200/45035119/e471ae53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45040000/45035200/45035119/2fcb2d1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shared fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/46000000/45040000/45035200/45035119/c2b6d037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/46000000/45040000/45035200/45035119/566cc0a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Victorian Inn Cathedral, 1.4 km from Sanford USD Medical Center 8.8/10 Excellent (56) "It was a great place to stay and super interesting." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy CA $199 CA $241 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Sioux-Falls-Hotels-Historic-Victorian-Inn.h45035119.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4800/4722/34cad0f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/4800/4722/1920c746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/4800/4722/a50b7486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4800/4722/2df9adda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Sioux Falls-City Centre by IHG Downtown Sioux Falls, 1.8 km from Sanford USD Medical Center 8.6/10 Excellent (1009) "Always a great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawn CA $140 CA $184 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Sioux-Falls-Hotels-Holiday-Inn-Sioux-Falls-City-Centre.h4722.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/119000/118966/c06c9122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/119000/118966/749ebeb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/119000/118966/bd8a3927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/119000/118966/d3008417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Sioux Falls Hotel & Convention Center Northwest Sioux Falls, 2.8 km from Sanford USD Medical Center 8.6/10 Excellent (1003) "Great hotel. Staff was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristina CA $149 CA $166 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Sioux-Falls-Hotels-Sheraton-Sioux-Falls-Convention-Center.h118966.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/9ba9d9dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/96cc4a2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/f9a72157.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/3f5c4ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Sioux Falls, SD Downtown Sioux Falls, 1.9 km from Sanford USD Medical Center 8.4/10 Very good (1146) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $143 CA $159 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Sioux-Falls-Hotels-Country-Inn-Suites-By-Radisson.h34225.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/cce804ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/e6d45314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite 1 King, MF, Recliner, Loveseat | Living area](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/e1654367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/2f94c1d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Center Inn All Saints, 2.3 km from Sanford USD Medical Center 8.4/10 Very good (693) "Clean room and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Betty [](https://www.expedia.ca/Sioux-Falls-Hotels-The-Center-Inn.h59829643.Hotel-Information) ![3 indoor pools, open 9:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/14200/14107/d8a57168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14200/14107/08b6bbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/14200/14107/00b636fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Arcade](https://images.trvl-media.com/lodging/1000000/20000/14200/14107/1c831ee9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr Northwest Sioux Falls, 2.9 km from Sanford USD Medical Center 7.8/10 Good (1452) "Everything was wonderful: Airport shuttle, room, breakfast, waterpark area, staff. What a great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine CA $82 CA $92 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Sioux-Falls-Hotels-Ramada-By-Wyndham-Sioux-Falls-Airport-Waterpark-Event-Ctr.h14107.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/1be1ec75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/05067e34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/1c1d99e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/92752fe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Valley Inn University Heights, 0.1 km from Sanford USD Medical Center 7.6/10 Good (1006) "Room was clean, staff was friendly, very convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa [](https://www.expedia.ca/Sioux-Falls-Hotels-Valley-Inn.h3886239.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40700/40621/f8bdcdf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40700/40621/76cea52f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/40700/40621/4ba92d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40700/40621/a1ad628e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Sioux Falls 2.7 km from Sanford USD Medical Center 5.6/10 (1004) "Clean room, great breakfast!, courteous staff....definately recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juliet CA $67 CA $76 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Sioux-Falls-Hotels-Ramada-By-Wyndham-Sioux-Falls.h40621.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058974/e8e2217c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058974/c9b97756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058974/51faf8ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058974/fda11aab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites Sioux Falls 2.9 km from Sanford USD Medical Center 5.2/10 (60) "The price was good, the cleanliness was better than other cheap hotels I've stayed in. My primary complaint was the slow internet speeds. There was also damage that had not been repaired from prior guests." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trent CA $97 CA $110 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Sioux-Falls-Hotels-WoodSpring-Suites-Sioux-Falls.h2058974.Hotel-Information) ![Dining room](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/8cefc211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/c8a90a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/630e0f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch flat-screen TV with cable channels, fireplace, Netflix](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/cc5b60f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Twin Tudors Inn 1.3 km from Sanford USD Medical Center 8.8/10 Excellent (3) "Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller CA $253 CA $291 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Sioux-Falls-Hotels-Historic-Twin-Tudors-Inn-Mc-Kennan-Park.h100455928.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/58000000/57890000/57889400/57889349/a24c12e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, alarm clocks](https://images.trvl-media.com/lodging/58000000/57890000/57889400/57889349/7011e938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, alarm clocks](https://images.trvl-media.com/lodging/58000000/57890000/57889400/57889349/f3e9512a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, alarm clocks](https://images.trvl-media.com/lodging/58000000/57890000/57889400/57889349/f6f21d78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Sioux Falls Arpt & Suites Northwest Sioux Falls, 2.9 km from Sanford USD Medical Center 7.0/10 Good (50) "Great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge [](https://www.expedia.ca/Sioux-Falls-Hotels-Ramada-By-Sioux-Falls-Airport-Hotel-Suites.h57889349.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/4accd249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/fdb6b2e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/89ab6f8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/03970b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Sioux Falls South Mall District, 3.8 km from Sanford USD Medical Center 9.4/10 Exceptional (1012) "Comfortable bed after a long trip, breakfast is good, I like the location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dulce ann CA $170 CA $189 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Sioux-Falls-Hotels-Hyatt-Place-Sioux-Falls-South.h53992029.Hotel-Information) ![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/49000000/48320000/48314600/48314557/a8b68d2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Kitchen](https://images.trvl-media.com/lodging/49000000/48320000/48314600/48314557/5faf8edb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/49000000/48320000/48314600/48314557/ef4e0bb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/49000000/48320000/48314600/48314557/1be86a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Sioux Falls Southwest by IHG South Sioux Falls, 5.3 km from Sanford USD Medical Center 9.6/10 Exceptional (451) "Always love staying here" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $134 CA $150 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Sioux-Falls-Hotels-Staybridge-Suites-Sioux-Falls-Southwest.h48314557.Hotel-Information) ![Room, Multiple Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/d6d757bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/21ef5a30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/d64e90ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/6cb8ef4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites at Sanford Sports Complex Northwest Sioux Falls, 6 km from Sanford USD Medical Center 9.6/10 Exceptional (875) "We had a quick overnight as part of a longer trip but the hotel was very clean, rooms were comfortable and breakfast got us on the road. Would stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris CA $140 CA $157 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Sioux-Falls-Hotels-Comfort-Inn-Suites-At-Sanford-Sports-Complex.h100310778.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7350000/7348000/7347907/a8e2f549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7350000/7348000/7347907/b6a49c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/8000000/7350000/7348000/7347907/64e37689.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/8000000/7350000/7348000/7347907/13a6006e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Avera Southwest South Sioux Falls, 5.6 km from Sanford USD Medical Center 9.4/10 Exceptional (1009) "The room was very clean, the beds were comfortable..enjoyed our stay:)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Valarie CA $143 CA $159 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Sioux-Falls-Hotels-Comfort-Inn-Suites-Avera-Southwest.h7347907.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11®ionId=553248621563219370&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Sanford USD Medical Center Hotel Reviews ![Hyatt Place Sioux Falls South](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/4accd249_y.jpg) ### Hyatt Place Sioux Falls South 10/10 Excellent "Longer drive to get to than we thought. Lake was small, but still nice." [](https://expedia.ca/Sioux-Falls-Hotels-Hyatt-Place-Sioux-Falls-South.h53992029.Hotel-Information) ![Hotel On Phillips](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/edd573eb_y.jpg) ### Hotel On Phillips 10/10 Excellent "Had hangers in room but no place to hang up clothes 704 and 604 . Otherwise great !" [](https://expedia.ca/Sioux-Falls-Hotels-Hotel-On-Phillips.h36447711.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Sioux Falls](https://images.trvl-media.com/lodging/8000000/7730000/7726800/7726793/b4415201_y.jpg) ### La Quinta Inn & Suites by Wyndham Sioux Falls 10/10 Excellent "The room was great. Beds were extra comfortable pool and the hot tub was not crowded all night overall just a very great experience." [](https://expedia.ca/Sioux-Falls-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Sioux-Falls.h7726793.Hotel-Information) ![Comfort Inn & Suites at Sanford Sports Complex](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/d6d757bd_y.jpg) ### Comfort Inn & Suites at Sanford Sports Complex 10/10 Excellent "Clean rooms, perfect temperature, pool was a little cold tho!" [](https://expedia.ca/Sioux-Falls-Hotels-Comfort-Inn-Suites-At-Sanford-Sports-Complex.h100310778.Hotel-Information) ![Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr](https://images.trvl-media.com/lodging/1000000/20000/14200/14107/d8a57168_y.jpg) ### Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr 10/10 Excellent "Pretty much except there was fake eyelashes in the shower! I almost had a heart attack!!" [](https://expedia.ca/Sioux-Falls-Hotels-Ramada-By-Wyndham-Sioux-Falls-Airport-Waterpark-Event-Ctr.h14107.Hotel-Information) ![Days Inn by Wyndham Sioux Falls Empire](https://images.trvl-media.com/lodging/1000000/10000/8300/8283/f89bacde_y.jpg) ### Days Inn by Wyndham Sioux Falls Empire 10/10 Excellent "Clea courteous pleasant hotel " [](https://expedia.ca/Sioux-Falls-Hotels-Days-Inn-By-Wyndham-Sioux-Falls-Empire.h8283.Hotel-Information) ![Country Inn & Suites by Radisson, Sioux Falls, SD](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/9ba9d9dd_y.jpg) ### Country Inn & Suites by Radisson, Sioux Falls, SD 10/10 Excellent "Great place" [](https://expedia.ca/Sioux-Falls-Hotels-Country-Inn-Suites-By-Radisson.h34225.Hotel-Information) ![Sleep Inn Sioux Falls Airport](https://images.trvl-media.com/lodging/1000000/10000/5800/5743/90b977df_y.jpg) ### Sleep Inn Sioux Falls Airport 10/10 Excellent "Every thing was great " [](https://expedia.ca/Sioux-Falls-Hotels-Sleep-Inn-Airport.h5743.Hotel-Information) ![The Center Inn](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/cce804ea_y.jpg) ### The Center Inn 10/10 Excellent "Room was clean like that its close to the hospital " [](https://expedia.ca/Sioux-Falls-Hotels-The-Center-Inn.h59829643.Hotel-Information) ## Hotels near other Sanford USD Medical Center attractions [](https://www.expedia.ca/Sioux-Empire-Medical-Museum-Hotels.0-l553248621532648850-0.Travel-Guide-Filter-Hotels) ### Sioux Empire Medical Museum You can spend time studying the exhibits at Sioux Empire Medical Museum in Sioux Falls. In the area, take in the entertainment choices and beautiful waterfalls. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532648850) [](https://www.expedia.ca/University-Of-Sioux-Falls-Hotels.0-l6090979-0.Travel-Guide-Filter-Hotels) ### University of Sioux Falls 4.1/5 (170 reviews) Take a campus tour or just explore the area of University of Sioux Falls, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6090979) [](https://www.expedia.ca/Augustana-College-Hotels.0-l6150272-0.Travel-Guide-Filter-Hotels) ### Augustana College 4.0/5 (188 reviews) Take a campus tour or just explore the area of Augustana College, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6150272) [](https://www.expedia.ca/Washington-Pavilion-Of-Arts-And-Science-Hotels.0-l6090975-0.Travel-Guide-Filter-Hotels) ### Washington Pavilion of Arts and Science 4.7/5 (63 reviews) You can enjoy a show at Washington Pavilion of Arts and Science on your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6090975) [](https://www.expedia.ca/Center-For-Western-Studies-Hotels.0-l553248621532648851-0.Travel-Guide-Filter-Hotels) ### Center for Western Studies You can spend time browsing the exhibits at Center for Western Studies in Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532648851) [](https://www.expedia.ca/Pettigrew-Home-And-Museum-Hotels.0-l553248621532648852-0.Travel-Guide-Filter-Hotels) ### Pettigrew Home and Museum You can spend time browsing the exhibits at Pettigrew Home and Museum during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532648852) [](https://www.expedia.ca/Delbridge-Museum-Of-Natural-History-Hotels.0-l6090987-0.Travel-Guide-Filter-Hotels) ### Delbridge Museum of Natural History You can spend time exploring the galleries in Delbridge Museum of Natural History during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6090987) [](https://www.expedia.ca/USS-South-Dakota-Battleship-Memorial-Hotels.0-l6091005-0.Travel-Guide-Filter-Hotels) ### USS South Dakota Battleship Memorial Find out about the history of Sioux Falls with a stop at USS South Dakota Battleship Memorial. Attend a sporting event or discover the area's beautiful waterfalls. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6091005) ## Frequently asked questions ### What's the area like around Sanford USD Medical Center? > Sanford USD Medical Center is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, check out the 111 hotels and other accommodations you'll find within a mile. ### Where is the best place to stay close to Sanford USD Medical Center? > Adjacent to Sanford USD Medical Center, [Valley Inn](https://www.expedia.ca/Sioux-Falls-Hotels-Valley-Inn.h3886239.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers free parking and free WiFi. Another good choice is [Home2 Suites By Hilton Sioux Falls/Sanford Medical Center](https://www.expedia.ca/Sioux-Falls-Hotels-Home2-Suites-By-Hilton-Sioux-FallsSanford-Medical-Center.h9011875.Hotel-Information), located just 0.1 mi (0.1 km) away. ### How many hotels should I expect to find close to Sanford USD Medical Center? > Expedia has 111 hotels and other accommodations within a mile from Sanford USD Medical Center. ### If I need to cancel the hotel reservation for my stay near Sanford USD Medical Center, will I receive a refund? > Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get the best deals available near Sanford USD Medical Center. ### What can I see and do near Sanford USD Medical Center? > Study the collections at Washington Pavilion of Arts and Science, Center for Western Studies, or Delbridge Museum of Natural History. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. Local parks like Falls Park, Sherman Park, and Veterans' Memorial Park are peaceful spots to stop and take in some fresh air. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [3 Star Hotels in Sioux Falls](https://www.expedia.ca/3Star-Sioux-Falls-Hotels.s30-0-d6059512.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Sioux Falls](https://www.expedia.ca/5Star-Sioux-Falls-Hotels.s50-0-d6059512.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in All Saints](https://www.expedia.ca/All-Saints-Sioux-Falls-Hotels-Pet-Friendly-Hotel.0-n897425033811746816-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels near Augustana College](https://www.expedia.ca/Augustana-College-Hotels.0-l6150272-0.Travel-Guide-Filter-Hotels) - [Baltic Hotels](https://www.expedia.ca/Baltic-Hotels.d553248634983447400.Travel-Guide-Hotels) - [Brandon Hotels](https://www.expedia.ca/Brandon-Hotels.d55065.Travel-Guide-Hotels) - [Pet-Friendly Hotels in Cathedral](https://www.expedia.ca/Cathedral-Sioux-Falls-Hotels-Pet-Friendly-Hotel.0-n897422941770502144-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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