Title: The 10 Best Hotels Near Sanford USD Medical Center, Sioux Falls from CA $75 | Expedia.ca

[Sioux Falls Travel Guide](https://expedia.ca/Sioux-Falls.dx6059512)[Vacation Rentals in Sioux Falls](https://expedia.ca/Sioux-Falls-Vacation-Rentals.d6059512.Travel-Guide-VacationRentals)[Flights to Sioux Falls](https://expedia.ca/Cheap-Flights-To-Sioux-Falls.d6059512.Travel-Guide-Flights)[Sanford USD Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Sanford-USD-Medical-Center.d553248621563219370.Car-Rental-Guide)[Sanford USD Medical Center Vacations](https://expedia.ca/Sanford-USD-Medical-Center-Sioux-Falls.d553248621563219370.Vacation-Attraction)

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## Check prices for these dates

Tonight

[Jan 21 - Jan 22](https://www.expedia.ca/Hotel-Search?regionId=553248621563219370&startDate=2026-01-21&endDate=2026-01-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 22 - Jan 23](https://www.expedia.ca/Hotel-Search?regionId=553248621563219370&startDate=2026-01-22&endDate=2026-01-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248621563219370&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248621563219370&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Sanford USD Medical Center hotels

![Interior detail](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/edd573eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed, River View (Blarney Stone King)](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/19a1b775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/93b8eb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed, River View (Chimney King)](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/a347316a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel On Phillips

[](https://www.expedia.ca/Sioux-Falls-Hotels-Hotel-On-Phillips.h36447711.Hotel-Information)

Downtown Sioux Falls, 1.8 km from Sanford USD Medical Center

9.6/10

Exceptional

(1,336 reviews)

"Nice place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andy

CA $273

CA $302 total

includes taxes & fees

Feb 2 - Feb 3

[](https://www.expedia.ca/Sioux-Falls-Hotels-Hotel-On-Phillips.h36447711.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9020000/9011900/9011875/10270e0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/10000000/9020000/9011900/9011875/7ff68e14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/10000000/9020000/9011900/9011875/w3837h2557x3y3-a3ae36e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/10000000/9020000/9011900/9011875/f0fde50d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

[](https://www.expedia.ca/Sioux-Falls-Hotels-Home2-Suites-By-Hilton-Sioux-FallsSanford-Medical-Center.h9011875.Hotel-Information)

University Heights, 0.1 km from Sanford USD Medical Center

9.4/10

Exceptional

(599 reviews)

"Clean room | Breakfast Great | Wonderful and Helpful Staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Natalie

CA $162

CA $181 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Sioux-Falls-Hotels-Home2-Suites-By-Hilton-Sioux-FallsSanford-Medical-Center.h9011875.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/4f6166ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/e6f72405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/4e8d1af3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/e9a40e2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clubhouse Hotel Suites Sioux Falls

[](https://www.expedia.ca/Sioux-Falls-Hotels-Clubhouse-Hotel-Suites-Sioux-Falls.h1100190.Hotel-Information)

Mall District, 2.9 km from Sanford USD Medical Center

9.6/10

Exceptional

(1,005 reviews)

"The stay was fantastic!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cleo

CA $210

CA $252 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Sioux-Falls-Hotels-Clubhouse-Hotel-Suites-Sioux-Falls.h1100190.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/282817a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/2f8dce6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/a83b67b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 Bedroom | Private kitchen](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/cf8c60fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Canopy By Hilton Sioux Falls Downtown

[](https://www.expedia.ca/Sioux-Falls-Hotels-Canopy-By-Hilton-Sioux-Falls-Downtown.h104094801.Hotel-Information)

Downtown Sioux Falls, 2.4 km from Sanford USD Medical Center

9.4/10

Exceptional

(169 reviews)

"Room was clean and the beds were pretty comfortable. The hotel is in a great location. Only issue, it’s way to close to Smithfield pork processing plant."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brett

CA $187

CA $214 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Sioux-Falls-Hotels-Canopy-By-Hilton-Sioux-Falls-Downtown.h104094801.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/9ba9d9dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/59d8aa71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/96cc4a2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/553fc343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites by Radisson, Sioux Falls

[](https://www.expedia.ca/Sioux-Falls-Hotels-Country-Inn-Suites-By-Radisson.h34225.Hotel-Information)

Downtown Sioux Falls, 1.9 km from Sanford USD Medical Center

8.4/10

Very good

(1,181 reviews)

"It was a great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Trinity

CA $115

CA $129 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Sioux-Falls-Hotels-Country-Inn-Suites-By-Radisson.h34225.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/7000000/6410000/6404700/6404700/w3837h2557x3y3-da1cbf43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6410000/6404700/6404700/8fd379c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/7000000/6410000/6404700/6404700/f7df70ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/7000000/6410000/6404700/6404700/w3836h2560x4y0-5db521c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Sioux Falls Downtown

[](https://www.expedia.ca/Sioux-Falls-Hotels-Hilton-Garden-Inn-Sioux-Falls-Downtown.h6404700.Hotel-Information)

Downtown Sioux Falls, 2 km from Sanford USD Medical Center

8.8/10

Excellent

(895 reviews)

"Friendly front desk staff, clean room, great location, safe "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hannah

CA $144

CA $166 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/Sioux-Falls-Hotels-Hilton-Garden-Inn-Sioux-Falls-Downtown.h6404700.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4800/4722/c76521c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/4800/4722/6ecf1dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed with Sofa bed, City View](https://images.trvl-media.com/lodging/1000000/10000/4800/4722/815973f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/4800/4722/a50b7486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Sioux Falls-City Centre by IHG

[](https://www.expedia.ca/Sioux-Falls-Hotels-Holiday-Inn-Sioux-Falls-City-Centre.h4722.Hotel-Information)

Downtown Sioux Falls, 1.8 km from Sanford USD Medical Center

8.6/10

Excellent

(1,003 reviews)

"staff was kind and helpful. the room was clean. The restaurant downstairs was handy and great food."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mia

CA $126

CA $141 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Sioux-Falls-Hotels-Holiday-Inn-Sioux-Falls-City-Centre.h4722.Hotel-Information)

![Porch](https://images.trvl-media.com/lodging/46000000/45040000/45035200/45035119/e471ae53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/46000000/45040000/45035200/45035119/2fcb2d1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shared fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/46000000/45040000/45035200/45035119/c2b6d037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/46000000/45040000/45035200/45035119/07efade6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Historic Victorian Inn

[](https://www.expedia.ca/Sioux-Falls-Hotels-Historic-Victorian-Inn.h45035119.Hotel-Information)

Cathedral, 1.4 km from Sanford USD Medical Center

8.8/10

Excellent

(56 reviews)

"It was a great place to stay and super interesting."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kathy

CA $168

CA $207 total

includes taxes & fees

Jan 26 - Jan 27

[](https://www.expedia.ca/Sioux-Falls-Hotels-Historic-Victorian-Inn.h45035119.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/120000/119000/118966/c06c9122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/120000/119000/118966/dd842284.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/119000/118966/bd8a3927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/120000/119000/118966/247f7239.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sheraton Sioux Falls Hotel & Convention Center

[](https://www.expedia.ca/Sioux-Falls-Hotels-Sheraton-Sioux-Falls-Convention-Center.h118966.Hotel-Information)

Northwest Sioux Falls, 2.8 km from Sanford USD Medical Center

8.6/10

Excellent

(1,000 reviews)

"Clean and friendly "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eddie

CA $146

CA $163 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Sioux-Falls-Hotels-Sheraton-Sioux-Falls-Convention-Center.h118966.Hotel-Information)

![Suite 2 Queens, Recliner, Pullout Sofa](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/ea709935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Handi 1 queen, MF, Recliner](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/3c5850aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/2e93ca6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/60000000/59830000/59829700/59829643/2f94c1d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Center Inn

[](https://www.expedia.ca/Sioux-Falls-Hotels-The-Center-Inn.h59829643.Hotel-Information)

All Saints, 2.3 km from Sanford USD Medical Center

8.4/10

Very good

(717 reviews)

"Room and staff were great. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Annette

[](https://www.expedia.ca/Sioux-Falls-Hotels-The-Center-Inn.h59829643.Hotel-Information)

![Basic Studio, 1 King Bed](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/38fc7edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/05067e34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/1c1d99e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/24e9ff66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Valley Inn

[](https://www.expedia.ca/Sioux-Falls-Hotels-Valley-Inn.h3886239.Hotel-Information)

University Heights, 0.1 km from Sanford USD Medical Center

7.8/10

Good

(1,000 reviews)

"Clean room Friendliness Great location for us "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rhonda or doug

[](https://www.expedia.ca/Sioux-Falls-Hotels-Valley-Inn.h3886239.Hotel-Information)

![50-inch flat-screen TV with cable channels, fireplace, Netflix](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/cc5b60f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/77757565.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining room](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/5fb9fa52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/c8a90a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Historic Twin Tudors Inn

[](https://www.expedia.ca/Sioux-Falls-Hotels-Historic-Twin-Tudors-Inn-Mc-Kennan-Park.h100455928.Hotel-Information)

1.3 km from Sanford USD Medical Center

8.8/10

Excellent

(3 reviews)

"Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

CA $372

CA $422 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Sioux-Falls-Hotels-Historic-Twin-Tudors-Inn-Mc-Kennan-Park.h100455928.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40700/40621/f8bdcdf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, Non Smoking (3 Queen Beds)](https://images.trvl-media.com/lodging/1000000/50000/40700/40621/3c7f8030.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/40700/40621/4ba92d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40700/40621/a1ad628e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ramada by Wyndham Sioux Falls

[](https://www.expedia.ca/Sioux-Falls-Hotels-Ramada-By-Wyndham-Sioux-Falls.h40621.Hotel-Information)

2.7 km from Sanford USD Medical Center

5.6/10

(1,001 reviews)

"Good room for the price."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

CA $66

CA $75 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Sioux-Falls-Hotels-Ramada-By-Wyndham-Sioux-Falls.h40621.Hotel-Information)

![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/121000000/120710000/120706800/120706759/24bd8fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio Suite, 1 King Bed](https://images.trvl-media.com/lodging/121000000/120710000/120706800/120706759/82416cbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/121000000/120710000/120706800/120706759/821a6546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/121000000/120710000/120706800/120706759/41b578f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Highpoint Hotel

[](https://www.expedia.ca/Sioux-Falls-Hotels-Highpoint-Hotel.h120706759.Hotel-Information)

University Heights, 0.3 km from Sanford USD Medical Center

CA $163

CA $182 total

includes taxes & fees

Feb 4 - Feb 5

[](https://www.expedia.ca/Sioux-Falls-Hotels-Highpoint-Hotel.h120706759.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/4accd249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/89ab6f8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/7e85057e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/54000000/54000000/53992100/53992029/03970b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place Sioux Falls South

[](https://www.expedia.ca/Sioux-Falls-Hotels-Hyatt-Place-Sioux-Falls-South.h53992029.Hotel-Information)

Mall District, 3.8 km from Sanford USD Medical Center

9.4/10

Exceptional

(1,000 reviews)

"Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nick

CA $162

CA $180 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/Sioux-Falls-Hotels-Hyatt-Place-Sioux-Falls-South.h53992029.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/8000000/7730000/7726800/7726793/b4415201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/8000000/7730000/7726800/7726793/4f3ca8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/8000000/7730000/7726800/7726793/0ab0f218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/8000000/7730000/7726800/7726793/e8087923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Sioux Falls

[](https://www.expedia.ca/Sioux-Falls-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Sioux-Falls.h7726793.Hotel-Information)

Mall District, 4.1 km from Sanford USD Medical Center

9.2/10

Wonderful

(1,560 reviews)

"The room was very clean, the staff was very friendly and professional, and the breakfast had a very nice variety of items."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Theresa

CA $119

CA $133 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Sioux-Falls-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Sioux-Falls.h7726793.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74429/5eaeb99e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/80000/74500/74429/1421b1c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74500/74429/9beb2ccd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Two Queens Study Sofabed Nonsmoking](https://images.trvl-media.com/lodging/1000000/80000/74500/74429/ff09a66b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sioux Falls

[](https://www.expedia.ca/Sioux-Falls-Hotels-Hampton-Inn-Sioux-Falls.h74429.Hotel-Information)

Mall District, 3.2 km from Sanford USD Medical Center

9.2/10

Wonderful

(1,001 reviews)

"It was a very nice stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lenore

CA $151

CA $168 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/Sioux-Falls-Hotels-Hampton-Inn-Sioux-Falls.h74429.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/251a34e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/1ad86be8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/4faa9df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/101000000/100320000/100310800/100310778/6ce38635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites at Sanford Sports Complex

[](https://www.expedia.ca/Sioux-Falls-Hotels-Comfort-Inn-Suites-At-Sanford-Sports-Complex.h100310778.Hotel-Information)

Northwest Sioux Falls, 6 km from Sanford USD Medical Center

9.6/10

Exceptional

(931 reviews)

"Very friendly staff and accommodating. Rooms were clean, quiet and beds were great. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erin

CA $131

CA $146 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Sioux-Falls-Hotels-Comfort-Inn-Suites-At-Sanford-Sports-Complex.h100310778.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1260000/1252800/1252731/49f47bbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1260000/1252800/1252731/821e93d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1260000/1252800/1252731/a1d70b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1260000/1252800/1252731/546d8b44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Staybridge Suites Sioux Falls by IHG

[](https://www.expedia.ca/Sioux-Falls-Hotels-Staybridge-Suites-Sioux-Falls.h1252731.Hotel-Information)

Mall District, 3.3 km from Sanford USD Medical Center

9.2/10

Wonderful

(1,001 reviews)

"Room was so nice we decided to stay an extra day and the lady at the front desk was super helpful with that! Would definitely stay here again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Victoria

CA $134

CA $150 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Sioux-Falls-Hotels-Staybridge-Suites-Sioux-Falls.h1252731.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/21000000/20160000/20154600/20154580/c0f8d747.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/21000000/20160000/20154600/20154580/c191214f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/21000000/20160000/20154600/20154580/1c571094.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/21000000/20160000/20154600/20154580/43b129df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn & Suites Sioux Falls - Airport by IHG

[](https://www.expedia.ca/Sioux-Falls-Hotels-Holiday-Inn-Hotel-Suites-Sioux-Falls-Airport.h20154580.Hotel-Information)

Northwest Sioux Falls, 3.3 km from Sanford USD Medical Center

9.2/10

Wonderful

(851 reviews)

"Clean Room. Beautiful pool and hot tub area. Great location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carissa

CA $148

CA $165 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Sioux-Falls-Hotels-Holiday-Inn-Hotel-Suites-Sioux-Falls-Airport.h20154580.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-05&endDate=2026-02-06&regionId=553248621563219370&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Sanford USD Medical Center Hotel Reviews

![Canopy By Hilton Sioux Falls Downtown](https://images.trvl-media.com/lodging/105000000/104100000/104094900/104094801/4a36c889_y.jpg)

### Canopy By Hilton Sioux Falls Downtown

10/10 Excellent

"Every nice amenities in a new, vibrant location in Sioux Falls. Room was very nice and the staff was very nice."

[](https://expedia.ca/Sioux-Falls-Hotels-Canopy-By-Hilton-Sioux-Falls-Downtown.h104094801.Hotel-Information)

![Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr](https://images.trvl-media.com/lodging/1000000/20000/14200/14107/d8a57168_y.jpg)

### Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

10/10 Excellent

"Great pool! And lifeguards that let your kids be kids!"

[](https://expedia.ca/Sioux-Falls-Hotels-Ramada-By-Wyndham-Sioux-Falls-Airport-Waterpark-Event-Ctr.h14107.Hotel-Information)

![Hampton Inn Sioux Falls](https://images.trvl-media.com/lodging/1000000/80000/74500/74429/ceab3d5c_y.jpg)

### Hampton Inn Sioux Falls

10/10 Excellent

"Clean room, breakfast area clean and well maintained."

[](https://expedia.ca/Sioux-Falls-Hotels-Hampton-Inn-Sioux-Falls.h74429.Hotel-Information)

![Country Inn & Suites by Radisson, Sioux Falls, SD](https://images.trvl-media.com/lodging/1000000/40000/34300/34225/9ba9d9dd_y.jpg)

### Country Inn & Suites by Radisson, Sioux Falls, SD

10/10 Excellent

"Clean room. Walking distance to shopping and places to eat. The water view is pretty and another nice area to walk around. "

[](https://expedia.ca/Sioux-Falls-Hotels-Country-Inn-Suites-By-Radisson.h34225.Hotel-Information)

![AeroStay Hotel](https://images.trvl-media.com/lodging/12000000/11270000/11268300/11268258/32d35456_y.jpg)

### AeroStay Hotel

10/10 Excellent

"Was nice and convenient"

[](https://expedia.ca/Sioux-Falls-Hotels-AeroStay-Hotel.h11268258.Hotel-Information)

![Hotel On Phillips](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/edd573eb_y.jpg)

### Hotel On Phillips

10/10 Excellent

"Parking was difficult but everything else was great"

[](https://expedia.ca/Sioux-Falls-Hotels-Hotel-On-Phillips.h36447711.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Sioux Falls](https://images.trvl-media.com/lodging/8000000/7730000/7726800/7726793/b4415201_y.jpg)

### La Quinta Inn & Suites by Wyndham Sioux Falls

10/10 Excellent

"The room was very clean, the staff was very friendly and professional, and the breakfast had a very nice variety of items."

[](https://expedia.ca/Sioux-Falls-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Sioux-Falls.h7726793.Hotel-Information)

![Baymont by Wyndham Sioux Falls](https://images.trvl-media.com/lodging/1000000/60000/50200/50114/ff2f8bab_y.jpg)

### Baymont by Wyndham Sioux Falls

10/10 Excellent

"Nice and clean!"

[](https://expedia.ca/Sioux-Falls-Hotels-Baymont-By-Wyndham-Sioux-Falls.h50114.Hotel-Information)

![Clubhouse Hotel Suites Sioux Falls](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/4e13e753_y.jpg)

### Clubhouse Hotel Suites Sioux Falls

10/10 Excellent

"The stay was fantastic!"

[](https://expedia.ca/Sioux-Falls-Hotels-Clubhouse-Hotel-Suites-Sioux-Falls.h1100190.Hotel-Information)

## Hotels near other Sanford USD Medical Center attractions

### Sioux Empire Medical Museum

You can spend time studying the exhibits at Sioux Empire Medical Museum in Sioux Falls. In the area, take in the entertainment choices and beautiful waterfalls. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648850)

### University of Sioux Falls

4.1/5 (170 reviews)

Take a campus tour or just explore the area of University of Sioux Falls, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6090979)

### Augustana College

4.0/5 (188 reviews)

Take a campus tour or just explore the area of Augustana College, during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6150272)

### Washington Pavilion of Arts and Science

4.7/5 (63 reviews)

You can enjoy a show at Washington Pavilion of Arts and Science on your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6090975)

### Center for Western Studies

You can spend time browsing the exhibits at Center for Western Studies in Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648851)

### Pettigrew Home and Museum

You can spend time browsing the exhibits at Pettigrew Home and Museum during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532648852)

### Delbridge Museum of Natural History

You can spend time exploring the galleries in Delbridge Museum of Natural History during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6090987)

### USS South Dakota Battleship Memorial

Find out about the history of Sioux Falls with a stop at USS South Dakota Battleship Memorial. Attend a sporting event or discover the area's beautiful waterfalls. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6091005)

## Frequently asked questions

### What's the area like around Sanford USD Medical Center?

### Where is the best place to stay close to Sanford USD Medical Center?

### How many hotels should I expect to find close to Sanford USD Medical Center?

### If I need to cancel the hotel reservation for my stay near Sanford USD Medical Center, will I receive a refund?

### What can I see and do near Sanford USD Medical Center?

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- [Tea Hotels ](https://www.expedia.ca/Tea-Hotels.d6346936.Travel-Guide-Hotels)
- [Hotels near University of Sioux Falls ](https://www.expedia.ca/University-Of-Sioux-Falls-Hotels.0-l6090979-0.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in West 10th Street ](https://www.expedia.ca/West-10th-Street-Sioux-Falls-Hotels-Pet-Friendly-Hotel.0-n897425306103865344-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
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- [Flights to Sioux Falls ](https://www.expedia.ca/Cheap-Flights-To-Sioux-Falls.d6059512.Travel-Guide-Flights)
- [Flights from Minnehaha County ](https://www.expedia.ca/lp/flights/553248635976433608/flights-from-minnehaha-county)
- [Flights from Sioux Falls ](https://www.expedia.ca/lp/flights/6059512/flights-from-sioux-falls)

- [Delbridge Museum of Natural History ](https://www.expedia.ca/Delbridge-Museum-Of-Natural-History-Sioux-Falls.d6090987.Vacation-Attraction)
- [Visit Folsom's Addition ](https://www.expedia.ca/Sioux-Falls-Folsoms-Addition.dx553248635976473553)
- [Visit McKennan Park ](https://www.expedia.ca/Sioux-Falls-McKennan-Park.dx897425214072446976)
- [Visit Pettigrew Heights ](https://www.expedia.ca/Sioux-Falls-Pettigrew-Heights.dx897423859844915200)
- [Sioux Falls Vacations ](https://www.expedia.ca/Sioux-Falls.d6059512.Destination-Travel-Guides)
- [Visit Sioux Falls ](https://www.expedia.ca/Sioux-Falls.dx6059512)

- [Car rental Sioux Falls ](https://www.expedia.ca/Car-Rentals-In-Sioux-Falls.d6059512.Car-Rental-Guide)