Title: Book the Best BUSINESS Hotels in Sanford in 2026 | Expedia.ca

[Sanford Travel Guide](https://expedia.ca/Sanford.dx183296)[Hotels in Sanford](https://expedia.ca/Sanford-Hotels.d183296.Travel-Guide-Hotels)[Vacation Rentals in Sanford](https://expedia.ca/Sanford-Vacation-Rentals.d183296.Travel-Guide-VacationRentals)[Flights to Sanford](https://expedia.ca/Cheap-Flights-To-Sanford.d183296.Travel-Guide-Flights)[Sanford Car Rentals](https://expedia.ca/Car-Rentals-In-Sanford.d183296.Car-Rental-Guide)[Sanford Vacation Packages](https://expedia.ca/Sanford.d183296.Destination-Travel-Guides)

![Public park lake overlook at Alton Bay Boston and Maine railroad depot.](https://images.trvl-media.com/place/183296/a0fe745c-ca8c-4c39-816d-f2e62580c123.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/183296/a0fe745c-ca8c-4c39-816d-f2e62580c123.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Sanford Business Hotels

Tonight

[Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=183296&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=183296&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=183296&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=183296&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Our top choices for Sanford business-friendly hotels

![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1094500/1094420/579e0ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1100000/1094500/1094420/f443f84e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1100000/1094500/1094420/a926a7a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/2000000/1100000/1094500/1094420/1d56b8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Coachman Inn

[](https://www.expedia.ca/Kittery-Hotels-Coachman-Inn.h1094420.Hotel-Information)

Kittery

7.8/10

Good

(1,000 reviews)

"Great place to stay."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Linda

[](https://www.expedia.ca/Kittery-Hotels-Coachman-Inn.h1094420.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/e27257a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/w3837h2557x3y3-f8960a09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/w3840h2557x0y3-0e30d920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/w3837h2557x3y3-34dcadbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Portsmouth Downtown

[](https://www.expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information)

Downtown

8.4/10

Very good

(230 reviews)

"Great staff and great location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $131

CA $142 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information)

![Individually furnished, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/330000/327900/327816/fd0001fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327900/327816/edbf4380.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/330000/327900/327816/7ac77382.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327900/327816/0a4db340.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ramada by Wyndham Saco/Old Orchard Beach Area

[](https://www.expedia.ca/Portland-Hotels-Ramada-By-Wyndham-SacoOld-Orchard-Beach-Area.h327816.Hotel-Information)

Saco

7.4/10

Good

(1,030 reviews)

"Room was nice, breakfast was good, room was clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen

CA $92

CA $100 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Portland-Hotels-Ramada-By-Wyndham-SacoOld-Orchard-Beach-Area.h327816.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/920000/918600/918502/5b50b547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/920000/918600/918502/791acc52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/920000/918600/918502/bd239ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/920000/918600/918502/4c6f8155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Biddeford by IHG

[](https://www.expedia.ca/Portland-Hotels-Holiday-Inn-Express-Biddeford.h918502.Hotel-Information)

Biddeford

8.2/10

Very good

(1,001 reviews)

"Clean room and good customer service. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erika

CA $120

CA $131 total

includes taxes & fees

Mar 5 - Mar 6

[](https://www.expedia.ca/Portland-Hotels-Holiday-Inn-Express-Biddeford.h918502.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/6e1e8681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 9:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/43e2fe11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fireplace](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/69c87334.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/f3058983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Port Inn and Suites Portsmouth, an Ascend Collection Hotel

[](https://www.expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information)

Portsmouth

8.2/10

Very good

(1,001 reviews)

"Great stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Max

CA $128

CA $139 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/4b84503a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/20be97f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/eef7beed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/429c2f1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel

[](https://www.expedia.ca/Portsmouth-Hotels-The-Garrison-Hotel-Suites-Dover-Durham.h17924431.Hotel-Information)

Dover

9.2/10

Wonderful

(1,000 reviews)

"Friendly staff, clean comfy rooms. Overall fantastic stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica

CA $132

CA $144 total

includes taxes & fees

Feb 26 - Feb 27

[](https://www.expedia.ca/Portsmouth-Hotels-The-Garrison-Hotel-Suites-Dover-Durham.h17924431.Hotel-Information)

![Indoor spa tub](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/f668ac0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor spa tub](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/50bc7b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/dbf3df9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/7c3975cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Meadowmere Resort

[](https://www.expedia.ca/Ogunquit-Hotels-Meadowmere-Resort.h1385319.Hotel-Information)

Ogunquit

8.6/10

Excellent

(1,000 reviews)

"We loved our stay- 10/10 would go back again!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

George

CA $190

CA $251 total

includes taxes & fees

Feb 11 - Feb 12

[](https://www.expedia.ca/Ogunquit-Hotels-Meadowmere-Resort.h1385319.Hotel-Information)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1070000/1062700/1062637/de86afbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast served](https://images.trvl-media.com/lodging/2000000/1070000/1062700/1062637/a9fc6bb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/2000000/1070000/1062700/1062637/123c0243.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/2000000/1070000/1062700/1062637/d2f90beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gorges Grant Hotel

[](https://www.expedia.ca/Ogunquit-Hotels-Gorges-Grant-Hotel.h1062637.Hotel-Information)

Ogunquit

9.6/10

Exceptional

(1,000 reviews)

"Very clean property close to the center of Ogunquit! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eileen

CA $190

CA $244 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Ogunquit-Hotels-Gorges-Grant-Hotel.h1062637.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/689b6164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/f64165b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/54cd3257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/a90c7ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Kittery-Portsmouth

[](https://www.expedia.ca/Kittery-Hotels-Hampton-Inn-Suites-Kittery.h29370772.Hotel-Information)

Kittery

9.2/10

Wonderful

(1,000 reviews)

"Excellent stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

angel

CA $139

CA $151 total

includes taxes & fees

Feb 26 - Feb 27

[](https://www.expedia.ca/Kittery-Hotels-Hampton-Inn-Suites-Kittery.h29370772.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w3840h2556x0y3-bb4935fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/fa2ba286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w1917h1279x0y1-7f4ff183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w3836h2558x4y4-d61330d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites By Hilton Kittery

[](https://www.expedia.ca/Kittery-Hotels-Home2-Suites-By-Hilton-Kittery.h118242928.Hotel-Information)

Kittery

9.4/10

Exceptional

(61 reviews)

"Room and hotel were super clean! Every staff member I encountered was friendly and professional- highly recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lisa

CA $150

CA $163 total

includes taxes & fees

Feb 11 - Feb 12

[](https://www.expedia.ca/Kittery-Hotels-Home2-Suites-By-Hilton-Kittery.h118242928.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20&regionId=183296&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Sanford Hotel Reviews

![Hampton Inn & Suites Portsmouth Downtown](https://images.trvl-media.com/lodging/9000000/8270000/8268900/8268861/b0df55fb_y.jpg)

### Hampton Inn & Suites Portsmouth Downtown

10/10 Excellent

"Friendly, helpful staff; very clean room."

[](https://expedia.ca/Portsmouth-Hotels-Hampton-Inn-Suites-Portsmouth-Downtown.h8268861.Hotel-Information)

![Meadowmere Resort](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/c1d22544_y.jpg)

### Meadowmere Resort

10/10 Excellent

"Beds were very comfortable. Front desk staff so nice"

[](https://expedia.ca/Ogunquit-Hotels-Meadowmere-Resort.h1385319.Hotel-Information)

![Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/429c2f1e_y.jpg)

### Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel

10/10 Excellent

"Great hotel except parking around is not convenient "

[](https://expedia.ca/Portsmouth-Hotels-The-Garrison-Hotel-Suites-Dover-Durham.h17924431.Hotel-Information)

![Anchorage Inn and Resort](https://images.trvl-media.com/lodging/10000000/9320000/9317700/9317652/68fa4886_y.jpg)

### Anchorage Inn and Resort

10/10 Excellent

"Check in was easy. Great parking! Love the indoor pool! Beautiful view! We have stayed here many times and love it!"

[](https://expedia.ca/York-Hotels-Anchorage-Inn-And-Resort.h9317652.Hotel-Information)

![The Hotel Portsmouth](https://images.trvl-media.com/lodging/1000000/20000/10300/10206/1247ecd5_y.jpg)

### The Hotel Portsmouth

10/10 Excellent

"Friendly welcoming staff, and on site breakfast was nice. room was nice."

[](https://expedia.ca/Portsmouth-Hotels-The-Hotel-Portsmouth.h10206.Hotel-Information)

![Anchorage by the Sea](https://images.trvl-media.com/lodging/13000000/12990000/12988900/12988895/a2365b37_y.jpg)

### Anchorage by the Sea

10/10 Excellent

"All of that! Food was great, loved having a gorgeous bathrobe to use, staff was so nice!"

[](https://expedia.ca/Ogunquit-Hotels-Anchorage-By-The-Sea.h12988895.Hotel-Information)

![Port Inn and Suites Portsmouth, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/6e1e8681_y.jpg)

### Port Inn and Suites Portsmouth, an Ascend Collection Hotel

10/10 Excellent

"Can't say enough positive things about Port Inn and Suites. This is not a luxurious place; however, it was quite clean. The towels were nice and white, and the bed was quite comfortable. It is also convenient to downtown and the hospital. The staff was also very nice and courteous. I would definitely stay there again. "

[](https://expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information)

![Cliff House Maine](https://images.trvl-media.com/lodging/4000000/3990000/3981200/3981160/eb122fc0_y.jpg)

### Cliff House Maine

10/10 Excellent

"The room was incredibly clean and beautiful. We loved our view from the balcony. The staff was l incredibly friendly. We enjoyed spending time at the fireplace each night."

[](https://expedia.ca/Cape-Neddick-Hotels-Cliff-House-Maine.h3981160.Hotel-Information)

![Hilton Garden Inn Portsmouth Downtown](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/7de77d01_y.jpg)

### Hilton Garden Inn Portsmouth Downtown

10/10 Excellent

"Quick one night getaway! Everything was perfect!"

[](https://expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information)

## Frequently asked questions

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- [Flights from Springvale ](https://www.expedia.ca/lp/flights/3000440318/flights-from-springvale)
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- [Visit York County ](https://www.expedia.ca/York-County.dx553248635976433774)

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