Title: Book the Best BUSINESS Hotels in Sanford in 2025 | Expedia.ca [Sanford Travel Guide](https://expedia.ca/Sanford.dx183296)[Hotels in Sanford](https://expedia.ca/Sanford-Hotels.d183296.Travel-Guide-Hotels)[Vacation Rentals in Sanford](https://expedia.ca/Sanford-Vacation-Rentals.d183296.Travel-Guide-VacationRentals)[Flights to Sanford](https://expedia.ca/Cheap-Flights-To-Sanford.d183296.Travel-Guide-Flights)[Things to do in Sanford](https://expedia.ca/Things-To-Do-In-Sanford.d183296.Travel-Guide-Activities)[Sanford Car Rentals](https://expedia.ca/Car-Rentals-In-Sanford.d183296.Car-Rental-Guide)[Sanford Vacation Packages](https://expedia.ca/Sanford.d183296.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Sanford, ME from CA $182 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sanford Business Hotels Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=183296&startDate=2025-09-27&endDate=2025-09-28&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=183296&startDate=2025-09-28&endDate=2025-09-29&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=183296&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=183296&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sanford Business Hotels ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/180000/179400/179323/2e5b10f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/179400/179323/15028876.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/179400/179323/94d8519e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/180000/179400/179323/d57a6dc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Sanford 7.8/10 Good (642) "Clean and quiet with a walmart walking distance." CA $167 CA $182 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Sanford-Hotels-Quality-Inn.h179323.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-12&endDate=2025-10-13®ionId=183296&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Sanford Hotel Reviews ![Port Inn and Suites Portsmouth, an Ascend Collection Hotel](//images.trvl-media.com/lodging/1000000/900000/894200/894133/c1712c91_y.jpg) ### Port Inn and Suites Portsmouth, an Ascend Collection Hotel 10/10 Excellent "Amazing " [](https://expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information) ![The Colony Hotel](//images.trvl-media.com/lodging/1000000/30000/26500/26416/7cbf624a_y.jpg) ### The Colony Hotel 10/10 Excellent "Very cozy historic hotel!" [](https://expedia.ca/Portland-Hotels-The-Colony-Hotel.h26416.Hotel-Information) ![Hampton Inn & Suites Portsmouth Downtown](//images.trvl-media.com/lodging/9000000/8270000/8268900/8268861/b0df55fb_y.jpg) ### Hampton Inn & Suites Portsmouth Downtown 10/10 Excellent "No" [](https://expedia.ca/Portsmouth-Hotels-Hampton-Inn-Suites-Portsmouth-Downtown.h8268861.Hotel-Information) ![Anchorage Inn and Resort](//images.trvl-media.com/lodging/10000000/9320000/9317700/9317652/68fa4886_y.jpg) ### Anchorage Inn and Resort 10/10 Excellent "Great resort, excellent location, you can hear the waves At your door. Friendly staff, pool areas are inviting. Stayed many times and will return. " [](https://expedia.ca/York-Hotels-Anchorage-Inn-And-Resort.h9317652.Hotel-Information) ![Ogunquit - The Milestone](//images.trvl-media.com/lodging/2000000/1070000/1060100/1060087/00a445d7_y.jpg) ### Ogunquit - The Milestone 10/10 Excellent "Clean room, affordable." [](https://expedia.ca/Ogunquit-Hotels-The-Milestone.h1060087.Hotel-Information) ![Motel 6 Portsmouth, NH](//images.trvl-media.com/lodging/1000000/1000000/996300/996239/10ee4974_y.jpg) ### Motel 6 Portsmouth, NH 10/10 Excellent "NA" [](https://expedia.ca/Portsmouth-Hotels-Motel-6-Portsmouth.h996239.Hotel-Information) ![Anchor Inn and Cottages Wells-Ogunquit](//images.trvl-media.com/lodging/6000000/5990000/5983100/5983030/f55e30b7_y.jpg) ### Anchor Inn and Cottages Wells-Ogunquit 10/10 Excellent "It was very well kept. The only problem finger prints on the ceiling lol. I will be staying there with family in the future." [](https://expedia.ca/Wells-Hotels-Americas-Best-Value-Inn-Cottages-Wells-Ogunquit.h5983030.Hotel-Information) ![Ramada by Wyndham Saco/Old Orchard Beach Area](//images.trvl-media.com/lodging/1000000/330000/327900/327816/fd0001fb_y.jpg) ### Ramada by Wyndham Saco/Old Orchard Beach Area 10/10 Excellent "The staff were very great with our late arrival and letting us know we could check out later if needed. They got us checked in very fast. It was quiet and breakfast was not bad either. Not to mention we booked same day and paid a good price for the room! Will absolutely go here again if I get the chance too! " [](https://expedia.ca/Portland-Hotels-Ramada-By-Wyndham-SacoOld-Orchard-Beach-Area.h327816.Hotel-Information) ![Meadowmere Resort](//images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/c1d22544_y.jpg) ### Meadowmere Resort 10/10 Excellent "Outdoor pool and hot tub " [](https://expedia.ca/Ogunquit-Hotels-Meadowmere-Resort.h1385319.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Sanford cost? > You'll pay between CA $182 and CA $182 per night for business-friendly hotels in Sanford. Awesome deals on stays that cater to people travelling for work as just a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### Why book your business-friendly hotel in Sanford with Expedia? > With handy amenities like conference rooms, laundry facilities and free parking, our business-friendly properties come with everything you'll need to get the job done — and then kick back! Enter your preferred travel dates and destination and we'll help you plan the rest. ### How can I find cheap business-friendly hotels in Sanford? > When work takes you to Sanford, our "business friendly" filter will help you find the perfect hotel. From WiFi to meeting rooms and work desks, they come with the amenities you need for a productive and comfortable stay. Another handy tip? Narrow your search by your budget and preferred star rating to see the most affordable stays. ### What is there to do in Sanford near my business-friendly hotel? > Sanford has enough sights and activities to keep you busy for weeks, starting with [Bowl A Rama](https://www.expedia.ca/Bowl-A-Rama-Sanford.d553248621532667579.Vacation-Attraction). [Mousam Lake](https://www.expedia.ca/Mousam-Lake-Shapleigh.d553248635976194435.Vacation-Attraction), [Kennebunk Pond](https://www.expedia.ca/Kennebunk-Pond-Lyman.d553248635975748929.Vacation-Attraction) and [Blueberry Hill](https://www.expedia.ca/Blueberry-Hill-Acton.d553248621532667578.Vacation-Attraction) are other well-known attractions. If your business trip gives you time to spare, [Swan Pond](https://www.expedia.ca/Swan-Pond-Lyman.d553248635975749293.Vacation-Attraction) and [Pine Hollow Little Par Three Golf Course](https://www.expedia.ca/Pine-Hollow-Little-Par-Three-Golf-Course-Sanford.d553248621532667577.Vacation-Attraction) are great additions to your itinerary. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Other - More ways to book - [Cheap Hotels in Acton](https://www.expedia.ca/Acton-Hotels-Cheap-Hotels.0-0-d3000421200-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Acton](https://www.expedia.ca/Acton-Hotels-Hotel-With-Pool.0-0-d3000421200-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Acton](https://www.expedia.ca/Acton-Hotels-Luxury-Hotel.0-0-d3000421200-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Farmstay in Alfred](https://www.expedia.ca/Alfred-Agritourism.d3000421204-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Alfred](https://www.expedia.ca/Alfred-Apart-Hotels.d3000421204-aaApartHotels.Travel-Guide-Accommodation) - 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[Flights from Niagara Falls (IAG) to Sanford (SFM)](https://www.expedia.ca/lp/flights/iag/sfm/niagara-falls-to-sanford) - [Flights from Islip (ISP) to Sanford (SFM)](https://www.expedia.ca/lp/flights/isp/sfm/islip-to-sanford) - [Flights from Lome (LFW) to Sanford (SFM)](https://www.expedia.ca/lp/flights/lfw/sfm/lome-to-sanford) - [Flights from Miami (MIA) to Sanford (SFM)](https://www.expedia.ca/lp/flights/mia/sfm/miami-to-sanford) - [Flights from Ogdensburg (OGS) to Sanford (SFM)](https://www.expedia.ca/lp/flights/ogs/sfm/ogdensburg-to-sanford) - [Flights from Ontario (ONT) to Sanford (SFM)](https://www.expedia.ca/lp/flights/ont/sfm/ontario-to-sanford) - [Flights from Plattsburgh (PBG) to Sanford (SFM)](https://www.expedia.ca/lp/flights/pbg/sfm/plattsburgh-to-sanford) - [Flights from Portsmouth (PSM) to Sanford (SFM)](https://www.expedia.ca/lp/flights/psm/sfm/portsmouth-to-sanford) - [Flights from South Bend (SBN) to Sanford (SFM)](https://www.expedia.ca/lp/flights/sbn/sfm/south-bend-to-sanford) - [Flights from Orange County (SNA) to Sanford (SFM)](https://www.expedia.ca/lp/flights/sna/sfm/orange-county-to-sanford) - [Flights from Syracuse (SYR) to Sanford (SFM)](https://www.expedia.ca/lp/flights/syr/sfm/syracuse-to-sanford) - [Flights from Windsor (YQG) to Sanford (SFM)](https://www.expedia.ca/lp/flights/yqg/sfm/windsor-to-sanford) - [Flights from Montreal (YUL) to Sanford (SFM)](https://www.expedia.ca/lp/flights/yul/sfm/montreal-to-sanford) - [Flights from Vancouver (YVR) to Sanford (SFM)](https://www.expedia.ca/lp/flights/yvr/sfm/vancouver-to-sanford) - [Flights from Toronto (YYZ) to Sanford (SFM)](https://www.expedia.ca/lp/flights/yyz/sfm/toronto-to-sanford) - [Visit York County](https://www.expedia.ca/York-County.dx553248635976433774) - [Things to do in Alfred](https://www.expedia.ca/Things-To-Do-In-Alfred.d3000421204.Travel-Guide-Activities) - [Book Business Hotels in Sanford on Expedia.com](https://www.expedia.com/Sanford-Hotels-Business-Hotel.0-0-d183296-tBusinessHotel.Travel-Guide-Filter-Hotels)