Title: Book the Best ADVENTURE Hotels in Sanctuary in 2026 | Expedia.ca [Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanctuary Car Rentals](https://expedia.ca/Car-Rentals-In-Sanctuary.d553248635976469368.Car-Rental-Guide)[Sanctuary Vacations](https://expedia.ca/Sanctuary.d553248635976469368.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sanctuary Hotels & Resorts for Couples Tonight [Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Sanctuary adventure hotels ![3 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/9bc89705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/6ac4649e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/3202bde7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/2e8856cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) Fort Myers Beach 9.0/10 Wonderful (1,194 reviews) "Clean room, great restaurants in site." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $224 CA $281 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/8dde6ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast (USD 15.95 per person)](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/fc5edcf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d3bc3b9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/dbfba1a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Ft Myers [](https://www.expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) Villas 8.8/10 Excellent (1,006 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica CA $273 CA $304 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/72000000/71520000/71510500/71510479/fd9f5b33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71520000/71510500/71510479/5ab84c15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/72000000/71520000/71510500/71510479/340533d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/72000000/71520000/71510500/71510479/9d47b344.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### RARE FIND COASTAL COZY BRIGHT 2BR 2BATH HOME! 10MINS AWAY TO THE BEACH! [](https://www.expedia.ca/Cape-Coral-Hotels-Cape-Coastal-Paradise-Apartment.h71510479.Hotel-Information) Hancock 10/10 Exceptional (13 reviews) "Really clean really nice, easy," ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin D. CA $160 CA $467 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Cape-Coral-Hotels-Cape-Coastal-Paradise-Apartment.h71510479.Hotel-Information) ![In-room safe, blackout drapes, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1070000/1060300/1060289/41623a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1070000/1060300/1060289/98f67c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1070000/1060300/1060289/60960cb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/2000000/1070000/1060300/1060289/e4d12663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Ybel Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Casa-Ybel-Resort.h1060289.Hotel-Information) Mid Island 8.6/10 Excellent (297 reviews) "Clean rooms, great staff, beautiful view " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julia CA $858 CA $957 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Fort-Myers-Hotels-Casa-Ybel-Resort.h1060289.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/101000000/100460000/100458000/100457957/4372bc89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100460000/100458000/100457957/24069f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100460000/100458000/100457957/6facf7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100460000/100458000/100457957/7b0b57a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cute Studio in Cape Coral [](https://www.expedia.ca/Cape-Coral-Hotels-Cute-Studio-In-Cape-Coral.h100457957.Hotel-Information) Hancock 9.8/10 Exceptional (11 reviews) "Had a great time everything was perfect" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Michael H. CA $143 CA $307 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Cape-Coral-Hotels-Cute-Studio-In-Cape-Coral.h100457957.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/35000000/34350000/34341900/34341890/c6cc95bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34350000/34341900/34341890/d635245e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34350000/34341900/34341890/cd14c2f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34350000/34341900/34341890/1481a347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Location!! Location!!! Gulf Access Villa in SE Area [](https://www.expedia.ca/Cape-Coral-Hotels-Location-Location-Gulf-Access-Villa-In-SE-Area.h34341890.Hotel-Information) Caloosahatchee 8.6/10 Excellent (14 reviews) "Very comfortable, nicely decorated. Felt like home." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon P. [](https://www.expedia.ca/Cape-Coral-Hotels-Location-Location-Gulf-Access-Villa-In-SE-Area.h34341890.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/fc4aab98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/c2f2df8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/f302f039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pink Shell Beach Resort and Marina [](https://www.expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) Fort Myers Beach 9.4/10 Exceptional (1,257 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robyn CA $565 CA $720 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/125000000/124220000/124211300/124211300/84639c01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books](https://images.trvl-media.com/lodging/125000000/124220000/124211300/124211300/76b6dc5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/125000000/124220000/124211300/124211300/d2813c6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/125000000/124220000/124211300/124211300/244a717a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Perfect 3-bedroom house with AC in soothing Fort Myers [](https://www.expedia.ca/Fort-Myers-Hotels-Perfect-3-Bedroom-House-With-AC-In-Soothing-Fort-Myers.h124211300.Hotel-Information) Cypress Lake CA $175 CA $442 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Fort-Myers-Hotels-Perfect-3-Bedroom-House-With-AC-In-Soothing-Fort-Myers.h124211300.Hotel-Information) ![On the beach](https://images.trvl-media.com/lodging/113000000/112120000/112111100/112111012/w2457h1202x0y0-f73aded8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/113000000/112120000/112111100/112111012/7f10c686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, internet, bed sheets](https://images.trvl-media.com/lodging/113000000/112120000/112111100/112111012/5fe177e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![A heated pool](https://images.trvl-media.com/lodging/113000000/112120000/112111100/112111012/f0b3dbc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Playa #704- Captain's Cabin [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Casa-Playa-704-Captains-Cabin.h112111012.Hotel-Information) Fort Myers Beach 10/10 Exceptional (2 reviews) "Great place for a quick weekend at the beach. Clean and comfortable with everything you need for a beach trip. It's right on the beach and close to restaurants, bars and shopping. And it was half the cost of the resorts. We'll definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly S. CA $248 CA $504 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Casa-Playa-704-Captains-Cabin.h112111012.Hotel-Information) ![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/75000000/74130000/74124100/74124095/aabb25db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/75000000/74130000/74124100/74124095/e06d4932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games](https://images.trvl-media.com/lodging/75000000/74130000/74124100/74124095/w2044h1361x0y0-dad87139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/75000000/74130000/74124100/74124095/20780cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WINTER SALE - 1 BLOCK FROM THE BEACH - SLEEPS 8 - FREE WINE! [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-SUMMER-SALE-1-BLOCK-FROM-THE-BEACH-SLEEPS-8-FREE-WINE.h74124095.Hotel-Information) Mid Island 8.8/10 Excellent (25 reviews) "Very cute beachy themed accommodations, in a quiet neighborhood, steps to the beach with easy beach access! My family and I have been staying on Fort Myers Beach for the past 15 years, and I think we found our forever rental! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dena O. CA $342 CA $731 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-SUMMER-SALE-1-BLOCK-FROM-THE-BEACH-SLEEPS-8-FREE-WINE.h74124095.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19®ionId=553248635976469368&adults=2&nearby_group=recreation&sort=RECOMMENDED&openPlayBack=true) ## Top Sanctuary Hotel Reviews ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "Clean and modern room. Great view of the beach!" [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Great location, just wishes the pools bar would have been opened " [](https://expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![The Westin Cape Coral Resort At Marina Village](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e_y.jpg) ### The Westin Cape Coral Resort At Marina Village 10/10 Excellent "This is quite the oasis! It is surrounded by water. Guests have access to one pool and two additional pools a short distance away at a health center. The food on site is good, with additional restaurants on the property (marina side). There is a free boat trip each day to look for dolphins and other marine life. The room had a balcony overlooking the calm marina, which made it just perfect. Parking is easy in a covered parking garage on the property. I liked it so much I booked an additional night. The staff was reasonably friendly but not outgoing. Also, no Starbucks on site or very nearby. Otherwise, great place. " [](https://expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Room was nice and the place is beautiful! Staff was really nice and extremely helpful. " [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Tween Waters Island Resort & Spa](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/a5c54d2c_y.jpg) ### Tween Waters Island Resort & Spa 10/10 Excellent "Staff is excellent. Helpful and courteous. " [](https://expedia.ca/Fort-Myers-Hotels-Tween-Waters-Island-Resort-Spa.h170769.Hotel-Information) ![Doubletree by Hilton Fort Myers at Bell Tower Shops](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/704cf90c_y.jpg) ### Doubletree by Hilton Fort Myers at Bell Tower Shops 10/10 Excellent "Clean and great beds" [](https://expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "Clean room friendly staff great food and drinks attentive service promptly delivered anything we requested " [](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![The Lighthouse Resort Inn & Suites](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3_y.jpg) ### The Lighthouse Resort Inn & Suites 10/10 Excellent "Great bar and location " [](https://expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Sundial Beach Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/5481c209_y.jpg) ### Sundial Beach Resort & Spa 10/10 Excellent "Very clean room, staff was very nice. All of the pools were clean and everything was very nice and well taken care of. " [](https://expedia.ca/Sanibel-Hotels-Sundial-Beach-Resort-Spa.h1939.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Packages - More ways to book - [Hotels near Bowman's Beach ](https://www.expedia.ca/Bowmans-Beach-Hotels.0-l6296151-0.Travel-Guide-Filter-Hotels) - [Hotels near Captiva Beach ](https://www.expedia.ca/Captiva-Beach-Hotels.0-l6296288-0.Travel-Guide-Filter-Hotels) - [Cottages in Captiva ](https://www.expedia.ca/Captiva-Cottages.d86452-aaCottages.Travel-Guide-Accommodation) - [All Inclusive Resorts and in Captiva ](https://www.expedia.ca/Captiva-Hotels-All-Inclusive-Hotel.0-0-d86452-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Captiva ](https://www.expedia.ca/Captiva-Hotels-Beach-Hotel.0-0-d86452-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Captiva ](https://www.expedia.ca/Captiva-Hotels-Boutique-Hotel.0-0-d86452-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Captiva ](https://www.expedia.ca/Captiva-Hotels-Hotels-With-A-Lazy-River.0-0-d86452-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - 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