Title: Book the Best Sanctuary Adults Only Resorts & Hotels in 2026 from CA $144 | Expedia.ca [Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanctuary Car Rentals](https://expedia.ca/Car-Rentals-In-Sanctuary.d553248635976469368.Car-Rental-Guide)[Sanctuary Vacations](https://expedia.ca/Sanctuary.d553248635976469368.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/adultsonly.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/adultsonly.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sanctuary Adults Only Resorts & Hotels Tonight [Feb 2 - Feb 3](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2026-02-02&endDate=2026-02-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [Feb 3 - Feb 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2026-02-03&endDate=2026-02-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) No exact matches found, but these alternatives could be just right ## Recommended hotels in Sanctuary ![3 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/9bc89705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/bbf3ce91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/2e8856cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/3202bde7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) Fort Myers Beach 9.0/10 Wonderful (1,186 reviews) "Clean room, great restaurants in site." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $356 CA $428 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/0be36f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/98f0aac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/a9888e93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/a638e8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Allure Suites [](https://www.expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) McGregor 7.8/10 Good (1,004 reviews) "Good place to relax" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos rivera CA $129 CA $144 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/2c59b397.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/8bc2b39a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/3dc7bcd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Kayaking](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/94b7632c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Fort Myers Beach [](https://www.expedia.ca/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) Siesta Isle 8.8/10 Excellent (1,004 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea CA $361 CA $403 total includes taxes & fees Feb 28 - Mar 1 [](https://www.expedia.ca/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/c1a22212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/ead25301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 2 Bedrooms, Patio (waterview) | View from room](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/dcfa2de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 2 Bedrooms, Balcony (waterview) | Living area](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/8b91ec40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Matlacha on Shoreview [](https://www.expedia.ca/Cape-Coral-Hotels-Matlacha-At-Shoreview.h92421769.Hotel-Information) Cape Coral 9.6/10 Exceptional (227 reviews) "Very clean very nice staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward CA $61 CA $159 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/Cape-Coral-Hotels-Matlacha-At-Shoreview.h92421769.Hotel-Information) ![Signature Cottage](https://images.trvl-media.com/lodging/113000000/112650000/112646400/112646379/b1f43b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage | Private kitchen](https://images.trvl-media.com/lodging/113000000/112650000/112646400/112646379/015137d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Studio | Private kitchen](https://images.trvl-media.com/lodging/113000000/112650000/112646400/112646379/351017ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage](https://images.trvl-media.com/lodging/113000000/112650000/112646400/112646379/1e86e27c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Anchor Inn [](https://www.expedia.ca/Sanibel-Hotels-The-Anchor-Inn.h112646379.Hotel-Information) Mid Island CA $302 CA $358 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Sanibel-Hotels-The-Anchor-Inn.h112646379.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/a69cd385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/bd66e5bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/798de6a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible (Communications, Accessible Tub)](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/2f0290ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) Fort Myers Beach 9.4/10 Exceptional (1,002 reviews) "Nice place with friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott E. CA $244 CA $272 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) ![In-room safe, blackout drapes, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1070000/1060300/1060289/41623a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand, beach cabanas, sun loungers](https://images.trvl-media.com/lodging/2000000/1070000/1060300/1060289/e2a27b53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1070000/1060300/1060289/98f67c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1070000/1060300/1060289/60960cb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Ybel Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Casa-Ybel-Resort.h1060289.Hotel-Information) Mid Island 8.6/10 Excellent (297 reviews) "Clean rooms, great staff, beautiful view " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julia CA $856 CA $955 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Fort-Myers-Hotels-Casa-Ybel-Resort.h1060289.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/6f7b31fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/4358355b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/a68b2adb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/929af0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Fort Myers at Bell Tower Shops [](https://www.expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) Villas 8.8/10 Excellent (1,005 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandon CA $250 CA $279 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ![Floating Coconut Cottage Houseboat | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/1830d2aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Floating Coconut Cottage Houseboat | Living area](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/65803bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Floating Coconut Cottage Houseboat](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/0badd225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:30 AM to 9:30 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/bf04ece4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Resort & Marina [](https://www.expedia.ca/Fort-Myers-Hotels-Tip-Top-Isles-Waterfront-Resort-Marina.h5107225.Hotel-Information) Fort Myers Beach 8.6/10 Excellent (936 reviews) "Beautiful clean room friendly staff beautiful scenery" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cassie CA $191 CA $213 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Fort-Myers-Hotels-Tip-Top-Isles-Waterfront-Resort-Marina.h5107225.Hotel-Information) ![Outdoor pool, cabanas (surcharge), sun loungers](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/09777b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, beach bar](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/2c146761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/46216370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/6aafbca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Beach Resort Fort Myers [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) Fort Myers Beach 9.0/10 Wonderful (1,847 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaret CA $344 CA $452 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-16&endDate=2026-02-17®ionId=553248635976469368&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Sanctuary ### Discover top Sanctuary attractions Sanctuary neighbourhood offers a unique blend of tranquillity and adventure, perfect for families seeking quality experiences. Start your exploration at the stunning Sanctuary Woods Nature Preserve, where winding trails and serene woodlands allow for leisurely hikes and nature spotting, ideal for children to connect with the outdoors. For a bit of culture, the nearby Sanctuary Art Gallery showcases local artists, providing an engaging afternoon of creativity and inspiration. If your family enjoys interactive learning, the Sanctuary Science Centre offers hands-on exhibits that captivate both young minds and adults alike, making science fun and accessible. After a day of adventure, unwind at the local craft brewery, which features family-friendly spaces and a delightful menu showcasing regional flavours, perfect for a relaxed dinner. When it comes to accommodation, Sanctuary boasts several upscale hotels that cater to discerning travellers. Picture spacious suites equipped with modern amenities, attentive staff ready to accommodate your every need, and perhaps a pool where your children can splash about while you sip a cocktail by the poolside. Staying in Sanctuary means you can enjoy both high-quality lodgings and the convenience of nearby attractions, all while feeling pampered and taken care of. ## Top Sanctuary Hotel Reviews ## Explore a world of travel with Expedia - Lodging - Packages - More ways to book - [Hotels near Bowman's Beach ](https://www.expedia.ca/Bowmans-Beach-Hotels.0-l6296151-0.Travel-Guide-Filter-Hotels) - [Hotels near Captiva Beach ](https://www.expedia.ca/Captiva-Beach-Hotels.0-l6296288-0.Travel-Guide-Filter-Hotels) - [Cottages in Captiva ](https://www.expedia.ca/Captiva-Cottages.d86452-aaCottages.Travel-Guide-Accommodation) - [All Inclusive Resorts and in Captiva ](https://www.expedia.ca/Captiva-Hotels-All-Inclusive-Hotel.0-0-d86452-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Captiva ](https://www.expedia.ca/Captiva-Hotels-Beach-Hotel.0-0-d86452-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Captiva ](https://www.expedia.ca/Captiva-Hotels-Boutique-Hotel.0-0-d86452-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - 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