Title: Book the Best San Ysidro LUXURY Hotels - Upscale Hotels in San Ysidro, CA | Expedia.ca [San Ysidro Travel Guide](https://expedia.ca/San-Ysidro.dx8380)[Hotels in San Ysidro](https://expedia.ca/San-Ysidro-Hotels.d8380.Travel-Guide-Hotels)[Vacation Rentals in San Ysidro](https://expedia.ca/San-Ysidro-Vacation-Rentals.d8380.Travel-Guide-VacationRentals)[Flights to San Ysidro](https://expedia.ca/Cheap-Flights-To-San-Ysidro.d8380.Travel-Guide-Flights)[Things to do in San Ysidro](https://expedia.ca/Things-To-Do-In-San-Ysidro.d8380.Travel-Guide-Activities)[San Ysidro Car Rentals](https://expedia.ca/Car-Rentals-In-San-Ysidro.d8380.Car-Rental-Guide)[San Ysidro Vacation Packages](https://expedia.ca/San-Ysidro.d8380.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/1641e603bba22aeb090af9b9cb277d0e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Mona Zambrano # Find luxury hotels in San Ysidro, CA - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Ysidro Luxury Hotels Tonight [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-11-04&endDate=2025-11-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-11-05&endDate=2025-11-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top San Ysidro Luxury Hotels ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/9aa59122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 9:30 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/4b05f608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/2ba90811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/18c3e6b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Americana Inn San Ysidro 9.0/10 Wonderful (1178) "Staff was friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $147 CA $167 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/San-Ysidro-Hotels-Best-Western-Americana-Inn.h806327.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/490000/482200/482151/a5007327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/490000/482200/482151/1d2f5387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Triple Room](https://images.trvl-media.com/lodging/1000000/490000/482200/482151/927f9d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/490000/482200/482151/d5a59c6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Baja San Diego - A Boutique Hotel San Ysidro 7.4/10 Good (1002) "Super cute cultural ambiance. Very friendly staff, nice sized room, and a lovely pool area. Room floor needed mopping and breakfast was limited, but overall I completely enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan [](https://www.expedia.ca/San-Ysidro-Hotels-Hotel-Baja-San-Diego.h482151.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/57300/57235/79d129c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/57300/57235/3345797f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57300/57235/59ede676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/60000/57300/57235/19df6caa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Ysidro, CA - San Diego - Border San Ysidro 7.0/10 Good (1450) "Check in was quick, room was clean , Danny's restaurant right behind." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danny CA $89 CA $101 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/San-Ysidro-Hotels-Motel-6-San-Ysidro.h57235.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1200200/1200130/df5d1152.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Designer store](https://images.trvl-media.com/lodging/2000000/1210000/1200200/1200130/19b4bc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1200200/1200130/fcd2681d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/2000000/1210000/1200200/1200130/c0d74f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Primera San Ysidro 3.4/10 (607) "It needs to be demolish and rebuild it is dirty." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) fernando [](https://www.expedia.ca/San-Ysidro-Hotels-Hotel-Primera.h1200130.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/a90f2d6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/14f93e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/d8ecd896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/58b6effd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Suites San Ysidro, CA -San Diego South Bay San Ysidro 7.8/10 Good (1333) "Excelente hotel " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Adrian Andrés CA $97 CA $111 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/San-Ysidro-Hotels-Studio-6-Suites-San-Ysidro.h1798071.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-19&endDate=2025-11-20®ionId=8380&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top San Ysidro Hotel Reviews ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Amazing! " [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "The room and service was excellent. " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Handlery Hotel](//images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Clean room, friendly staff, and great service." [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Sheraton Mission Valley San Diego Hotel](//images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "Everything was great!!" [](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![Comfort Inn Sea World Area](//images.trvl-media.com/lodging/1000000/550000/544700/544662/44f458a2_y.jpg) ### Comfort Inn Sea World Area 10/10 Excellent "Very clean rooms and very accessible. Loved it." [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-Sea-World-Area.h544662.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Airport shuttle was the best. Rooms are ok with nice views. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Beautiful location and loved the pools." [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Pendry San Diego](//images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Great room and great staff! They really made our stay with their hospitality and efficiency. " [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![Loews Coronado Bay Resort](//images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864_y.jpg) ### Loews Coronado Bay Resort 10/10 Excellent "Beautiful hotel. The room was clean, quiet, and had a great view. The staff was excellent. The only complaint was the price of parking. 50 a day. We would definitely stay there again. " [](https://expedia.ca/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ## Frequently asked questions ### Which area of San Ysidro is best to stay in for luxury hotels? > The best area to stay in San Ysidro for luxury hotels is the vicinity of the Las Americas Premium Outlets, particularly along Camino de la Plaza. > > > > This area is the primary commercial hub of San Ysidro, offering modern facilities and direct access to high-end shopping. It's a convenient location for those looking for a comfortable stay with amenities close at hand. > > > > For travellers looking for a convenient stopover before or after crossing the border, this area is ideal. It provides easy access to the border crossing while offering a range of upscale accommodation options. ### How much does a luxury hotel in San Ysidro cost? > Luxury hotel prices in San Ysidro vary, but you can find a great deal from CA $101 on Expedia. To find the best prices on luxury stays, be flexible with your dates—typically, off-peak and mid-week stays are cheaper. Sort your search results by "Price: low to high" to see our lowest rates. ### How can I save on a luxury hotel in San Ysidro with Expedia? > There are plenty of ways to save on a luxury hotel in San Ysidro. Unlock our lowest prices by joining [One Key™](https://www.expedia.ca/welcome-one-key), Expedia's travel rewards program. It's free and easy to sign up, and you can access member perks too. Typically, booking in advance will help you save on your luxury hotel booking. If you're feeling spontaneous, be sure to check for last-minute deals. ### Is it cheaper to book a luxury San Ysidro hotel and flights as a package? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect [travel package](https://www.expedia.ca/San-Ysidro.d8380.Destination-Travel-Guides). ### Can I cancel my luxury hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. 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