Find Business Hotels in San Marco, FL from CA $117
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on San Marco Business Hotels
Top San Marco Business Hotels
Our top choices for San Marco business-friendly hotels

TownePlace Suites Jacksonville Airport
TownePlace Suites Jacksonville Airport
9.6 out of 10, Exceptional, (272)
The price is CA $164
CA $186 total
includes taxes & fees
Aug 31 - Sep 1

Holiday Inn Express Jacksonville - Blount Island by IHG
Holiday Inn Express Jacksonville - Blount Island by IHG
8.6 out of 10, Excellent, (1001)
The price is CA $142
CA $161 total
includes taxes & fees
Sep 7 - Sep 8

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
8.4 out of 10, Very good, (1009)
The price is CA $168
CA $190 total
includes taxes & fees
Sep 1 - Sep 2

Homewood Suites by Hilton Jacksonville Downtown-Southbank
Homewood Suites by Hilton Jacksonville Downtown-Southbank
8.6 out of 10, Excellent, (721)
The price is CA $176
CA $200 total
includes taxes & fees
Sep 14 - Sep 15

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
9.0 out of 10, Wonderful, (1007)
The price is CA $162
CA $184 total
includes taxes & fees
Sep 5 - Sep 6

Tru by Hilton Jacksonville West I 295
Tru by Hilton Jacksonville West I 295
9.0 out of 10, Wonderful, (162)
The price is CA $134
CA $153 total
includes taxes & fees
Sep 28 - Sep 29

Sheraton Jacksonville Hotel
Sheraton Jacksonville Hotel
9.2 out of 10, Wonderful, (1011)
The price is CA $164
CA $186 total
includes taxes & fees
Aug 31 - Sep 1

Holiday Inn Express & Suites Jacksonville W - I295 and I10 by IHG
Holiday Inn Express & Suites Jacksonville W - I295 and I10 by IHG
9.4 out of 10, Exceptional, (466)
The price is CA $168
CA $190 total
includes taxes & fees
Sep 7 - Sep 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top San Marco Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
More Hotel Options in San Marco
- Beach Hotel in San Marco
- Cheap Hotels in San Marco
- Family Hotels in San Marco
- Golf Hotels in San Marco
- Hotel Wedding Venues in San Marco
- Hotels & Resorts for Couples in San Marco
- Hotels with Balconies in San Marco
- Hotels with Bar in San Marco
- Hotels with Free Breakfast in San Marco
- Hotels with Hot Tubs in San Marco
- Hotels with Wifi in San Marco
- Hotels with a Pool in San Marco
- Hotels with smoking rooms in San Marco
- Pet-friendly Hotels in San Marco
- Shopping Hotels in San Marco
- Spa Hotels in San Marco
More Accommodation Types in San Marco
- Vacation Homes in Jacksonville
- Condo Rentals in Jacksonville
- Apartments in Jacksonville
- Cottages in Jacksonville
- Villas in Jacksonville
- Motels in Jacksonville
- Guest Houses in Jacksonville
- Aparthotels in Jacksonville
- B&B in Jacksonville
- Cabin Rentals in Jacksonville
- Resorts in Jacksonville
- Houseboats in Jacksonville
- Farmstay in Jacksonville
- RV Parks in Jacksonville
- Inns in Jacksonville
Hotels near popular Jacksonville Attractions
- Hotels near Theatre Jacksonville
- Hotels near San Marco Theatre
- Hotels near St. Johns Town Center
- Hotels near Mayo Clinic Florida
- Hotels near Jacksonville Naval Air Station
- Hotels near Jacksonville Cruise Terminal
- Hotels near EverBank Stadium
- Hotels near Jacksonville Zoo and Gardens
- Hotels near Mayport Naval Station
- Hotels near University of North Florida
San Marco Hotels by Star Rating
Explore more hotels
- DoubleTree by Hilton Hotel Jacksonville Riverfront
- Hampton Inn Jacksonville Beach/Oceanfront
- One Ocean Resort and Spa
- Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
- Courtyard by Marriott Jacksonville Beach Oceanfront
- Southbank Hotel by Marriott Jacksonville Riverwalk
- Holiday Inn Express & Suites Jacksonville Airport by IHG
- Weekly Inn
- Holiday Inn Express Jacksonville South Bartram Prk by IHG
- Springhill Suites By Marriott Jacksonville Beach Oceanfront
- Candlewood Suites Jacksonville Southpoint by IHG
- Comfort Suites Baymeadows Near Butler Blvd
- Windsor Inn of Jacksonville
- Hyatt Place Jacksonville / St. Johns Town Center
- WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk
- SpringHill Suites by Marriott Jacksonville Baymeadows
- Midtown Lodge
- Sheraton Jacksonville Hotel
- Best Western Oceanfront
- Delta Hotels by Marriott Jacksonville Deerwood
More ways to book
Expedia's Latest Trends
Hotels
- Hotels in Brickell
- Hotels in Downtown Tampa
- Hotels in Coconut Grove
- Hotels in Doral
- Hotels in Downtown Miami
- Hotels in Downtown Orlando
- Hotels in Wynwood Art District
- South Beach Cheap Hotels
- South Beach Boutique Hotels
- Hotels in Little Havana
- 5 Star Hotels in South Beach
- Hotels in South Beach
- South Beach Beach Hotel
- Hotels in Mid Beach
- South Beach Oceanfront Hotels
Packages