Title: Book the Best San Luis LUXURY Hotels - Upscale Hotels in San Luis, AZ | Expedia.ca

[Hotels in San Luis](https://expedia.ca/San-Luis-Hotels.d553248634983175106.Travel-Guide-Hotels)[Vacation Rentals in San Luis](https://expedia.ca/San-Luis-Vacation-Rentals.d553248634983175106.Travel-Guide-VacationRentals)[San Luis Car Rentals](https://expedia.ca/Car-Rentals-In-San-Luis.d553248634983175106.Car-Rental-Guide)[San Luis Vacation Packages](https://expedia.ca/San-Luis.d553248634983175106.Destination-Travel-Guides)

![Prehistoric cliffs in Sierra de las Quijadas National Park, San Luis, Argentina. Arid desert landscape. Red sandstone canyon and valley.](https://images.trvl-media.com/place/553248634983175106/8ba8511e-117f-4054-96ab-88b1bf1b4051.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find luxury hotels in San Luis, AZ

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## Check availability on San Luis Luxury Hotels

Tonight

[Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983175106&startDate=2025-12-27&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=553248634983175106&startDate=2025-12-28&endDate=2025-12-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248634983175106&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

In two weeks

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248634983175106&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Top San Luis Hotel Reviews

![Radisson Hotel Yuma](https://images.trvl-media.com/lodging/3000000/2410000/2410000/2409993/28b4bb48_y.jpg)

### Radisson Hotel Yuma

10/10 Excellent

"Staff was pleasant. Room was comfy. Will stay again. "

[](https://expedia.ca/Yuma-Hotels-Radisson-Hotel-Yuma.h2409993.Hotel-Information)

![La Fuente Inn & Suites](https://images.trvl-media.com/lodging/1000000/60000/50100/50057/c30df864_y.jpg)

### La Fuente Inn & Suites

10/10 Excellent

"Great place to stay. Loved everything from spacious rooms, great breakfast and swimming pool gardens area. "

[](https://expedia.ca/Yuma-Hotels-La-Fuente-Inn-Suites.h50057.Hotel-Information)

![Holiday Inn Express & Suites Yuma by IHG](https://images.trvl-media.com/lodging/2000000/1750000/1742900/1742824/ef77e1f1_y.jpg)

### Holiday Inn Express & Suites Yuma by IHG

10/10 Excellent

"The staff was amazing "

[](https://expedia.ca/Yuma-Hotels-Holiday-Inn-Express-Suites-Yuma.h1742824.Hotel-Information)

![Days Inn by Wyndham Yuma](https://images.trvl-media.com/lodging/1000000/20000/16900/16837/071aaafc_y.jpg)

### Days Inn by Wyndham Yuma

10/10 Excellent

"The room was great, bed was comfortable, and the bathroom spotless. One small suggestion, install a ceiling fan so that the AC air circulates better thru the room."

[](https://expedia.ca/Yuma-Hotels-Days-Inn-By-Wyndham-Yuma.h16837.Hotel-Information)

![Motel 6 Yuma, AZ - East](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037701/e9d2c60a_y.jpg)

### Motel 6 Yuma, AZ - East

10/10 Excellent

"Everything was good"

[](https://expedia.ca/Yuma-Hotels-Motel-6-Yuma.h1037701.Hotel-Information)

![Wingate by Wyndham Yuma](https://images.trvl-media.com/lodging/2000000/1830000/1820800/1820795/bb3f13a6_y.jpg)

### Wingate by Wyndham Yuma

10/10 Excellent

"Clean room, excellent staff, best breakfast i ever had. "

[](https://expedia.ca/Yuma-Hotels-Wingate-By-Wyndham-Yuma.h1820795.Hotel-Information)

![Shilo Inn Hotel & Suites - Yuma](https://images.trvl-media.com/lodging/1000000/10000/8500/8427/6bd48f33_y.jpg)

### Shilo Inn Hotel & Suites - Yuma

10/10 Excellent

"One of the nicest rooms I have ever stayed in. Very modern, clean. Felt luxurious. Large modern hotel. Even has a gym."

[](https://expedia.ca/Yuma-Hotels-Shilo-Inn-Hotel-Suites-Yuma.h8427.Hotel-Information)

![Historic Coronado Motor Hotel by OYO](https://images.trvl-media.com/lodging/1000000/10000/3200/3162/6f5fbbf5_y.jpg)

### Historic Coronado Motor Hotel by OYO

10/10 Excellent

"Room was clean, i know its an older hotel. I really enjoy staying there, yes my room had a smoke oder but was easily overlooked. I stay there twice a year Thanksgiving and new year's and will keep comjng back. The price is right. Thank your"

[](https://expedia.ca/Yuma-Hotels-Historic-Coronado-Motor-Hotel.h3162.Hotel-Information)

## Frequently asked questions

### Are you searching for the perfect hotel for your luxury trip to San Luis?

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